Population and family studies of dihydropyrimidinuria: Prevalence, inheritance mode, and risk of fluorouracil toxicity

American Journal of Medical Genetics

Volumn 78, Issue 4, 1998, Pages 336-340

  Sumi, Satoshi ^a   Imaeda, Masayuki ^a   Kidouchi, Kiyoshi ^b   Ohba, Satoru ^a   Hamajima, Naoki ^a   Kodama, Kyoko ^c   Togari, Hajime ^a   Wada, Yoshiro ^a  

^a NAGOYA CITY UNIV MEDICAL SCHOOL   (Japan)

^b Nagoya City Higashi General Hospital   (Japan)

^c NAGOYA CITY PUBLIC HEALTH RESEARCH INSTITUTE   (Japan)

Author keywords

5 fluorouracil; Autosomal recessive mode of inheritance; Dihydrothymine; Dihydrouracil; Prevalence of dihydropyrimidinuria

Indexed keywords

5,6 DIHYDROTHYMINE; CREATININE; DIHYDROPYRIMIDINASE; DIHYDROURACIL; FLUOROURACIL; PYRIMIDINE DERIVATIVE; THYMINE; UNCLASSIFIED DRUG; URACIL;

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CHILD; CONTROLLED STUDY; FAMILIAL DISEASE; FEMALE; HETEROZYGOTE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMOZYGOTE; HUMAN; INBORN ERROR OF METABOLISM; INFANT; JAPAN; MAJOR CLINICAL STUDY; MALE; POPULATION GENETICS; PREVALENCE; PRIORITY JOURNAL; PYRIMIDINE METABOLISM; URINALYSIS;

ADULT; AMIDOHYDROLASES; CHILD; CHILD, PRESCHOOL; FEMALE; FLUOROURACIL; GENES, RECESSIVE; HOMOZYGOTE; HUMANS; INFANT; JAPAN; MALE; METABOLISM, INBORN ERRORS; NUCLEAR FAMILY; PREVALENCE; PYRIMIDINES; RISK; THYMINE; URACIL;

EID: 0031928495     PISSN: 15524825     EISSN: 15524833     Source Type: Journal    
DOI: 10.1002/(sici)1096-8628(19980724)78:4<336::aid-ajmg6>3.0.co;2-j     Document Type: Article

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