Human-derived vascular smooth muscle cells produce angiotensin II by changing to the synthetic phenotype

Journal of Cellular Physiology

Volumn 196, Issue 2, 2003, Pages 284-292

  Hu, Wen Yang ^a   Fukuda, Noboru ^a   Ikeda, Yukihiro ^a   Suzuki, Ryo ^a   Tahira, Yosiko ^a   Takagi, Hiroto ^a   Matsumoto, Koichi ^a   Kanmatsuse, Katsuo ^a   Mugishima, Hideo ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ANGIOTENSIN; ANTISENSE OLIGODEOXYNUCLEOTIDE; CANDESARTAN; CATHEPSIN D; CATHEPSIN G; CHYMASE; CHYMOSTATIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FIBRONECTIN; OSTEOCALCIN; OSTEOPONTIN; TEMOCAPRIL;

ARTICLE; CONTROLLED STUDY; DNA HYBRIDIZATION; HORMONE DETERMINATION; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; RADIOIMMUNOASSAY; VASCULAR DISEASE; VASCULAR SMOOTH MUSCLE;

ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CATHEPSIN D; CATHEPSINS; CELL DIVISION; CELLS, CULTURED; FIBRONECTINS; HUMANS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; OLIGONUCLEOTIDES, ANTISENSE; OLIGOPEPTIDES; PHENOTYPE; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; THIAZEPINES;

EID: 0038798710     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.10299     Document Type: Article

References (33)

1. Berk BC, Vekshtein V, Gordon HM, Tsuda T. 1989. Angiotensin-stimulated protein synthesis in cultured smooth muscle cells. Hypertension 13:305-314.
2. Bohnemeier H, Pinto YM, Horkay F, Toth M, Juhasz-Nagy A, Orzechowski HD, Bohm M, Paul M. 1998. Endothelin converting-enzyme-1 mRNA expression in human cardiovascular disease. Clin Exp Hypertens 20:417-437.
3. Bottger BA, Hedin U, Johansson S, Thyberg J. 1989. Integrin-type fibronectin receptors of rat arterial smooth muscle cells: Isolation, partial characterization, and role in cytoskeletal organization and control of differentiated properties. Differentiation 41:158-167.
4. Campbell DJ, Habener JF. 1986. Angiotensinogen gene is expressed and differentially regulated in multiple tissues of the rat. J Clin Invest 78:31-39.
5. Dzau VJ. 1984. Vascular renin-angiotensin: A possible autocrine or paracrine system in control of vascular function. J Cardiovasc Pharmacol 6:377-382.
6. Dzau VJ. 1986. Significance of the vascular renin-angiotensin pathway. Hypertension 8:553-559.
7. Dzau VJ. 1994. Cell biology and genetics of angiotensin in cardiovascular disease. J Hypertens Suppl 12:S3-S10.
8. Dzau VJ, Brody T, Ellison KE, Pratt RE, Ingelfinger JR. 1987. Tissue-specific regulation of renin expression in the mouse. Hypertension 9:11136-11141.
9. Faust PL, Kornfeld S, Chirgwin JM. 1985. Cloning and sequence analysis of cDNA for human cathepsin D. Proc Natl Acad Sci USA 82:4910-4914.
10. Frank DJ, Plamondon J, Hamet P. 1984. An increase in adenylate cyclase activity precedes DNA synthesis in cultured vascular smooth muscle cells. J Cell Physiol 119:41-45.
11. Fukami H, Okunishi H, Miyazaki M. 1998. Chymase: Its pathophysiological roles and inhibitors. Curr Pharm Des 4:439-453.
12. Fukuda N, Satoh C, Hu W-Y, Soma M, Kubo A, Kishioka H, Watanabe Y, Izumi Y, Kanmatsuse K. 1999a. Production of angiotensin II by homogeneous cultures of vascular smooth muscle cells from spontaneously hypertensive rats. Arterioscler Thromb Vasc Biol 19:1210-1217.
13. Fukuda N, Hu W-Y, Satoh C, Nakayama M, Kishioka H, Kubo A, Kanmatsuse K. 1999b. Contribution of synthetic phenotype on the enhanced angiotensin II-generating system in vascular smooth muscle cells from spontaneously hypertensive rats. J Hypertens 17:1099-1107.
14. Glukhova MA, Frid MG, Kotelainski VE. 1990. Developmental changes in expression of contractile and cytoskeletal proteins in human aortic smooth muscle. J Biol Chem 265:13042-13046.
15. Gohlke P, Bunning P, Unger T. 1992. Distribution and metabolism of angiotensin I and II in the blood vessel wall. Hypertension 20:151-157.
16. Hedin U, Bottger BA, Forsberg E, Johansson S, Thyberg J. 1989. A substrate of the cell-attachment sequence of fibronectin (Arg-Gly-Asp-Ser) is sufficient to promote transition of arterial smooth muscle cells from a contractile to a synthetic phenotype. Dev Biol 133:489-501.
17. Holycross JH, Saye J, Harrison JK, Peach MJ. 1992. Polymerase chain reaction analysis of renin in rat aortic smooth muscle. Hypertension 19:697-701.
18. Hoof T, Riordan JR, Tummler B. 1991. Quantitation of mRNA by the kinetic polymerase chain reaction assay: A tool for monitoring P-glycoprotein expression. Anal Biochem 196:161-169.
19. Hu WY, Fukuda N, Satoh C, Jian T, Kubo A, Nakayama M, Kishioka H, Kanmatsuse K. 2000. Phenotypic modulation by fibronectin enhances the angiotensin II-generating system in cultured vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 20:1500-1505.
20. Hu WY, Fukuda N, Nakayama M, Kishioka H, Kanmatsuse K. 2001. Development of ribozyme to rat PDGF A-chain mRNA as a gene therapy for arterial proliferation in hypertension. J Hypertens 19:203-212.
21. Kiefer MC, Bauer DM, Young D, Hermsen KM, Masiarz FR, Barr PJ. 1988. The cDNA and derived amino acid sequences for human and bovine matrix Gla protein. Nucleic Acids Res 16:5213.
22. Lowry OH, Rosebrough NJ, Farr AL, Randall J. 1951. Protein measurement with the folin phenol reagent. J Biol Chem 193:265-275.
23. Mocharla H, Mocharla R, Hocks ME. 1990. Coupled reverse transcription-polymerase chain reaction (RT-PCR) as a sensitive and rapid method for isozyme genotyping. Gene 93:271-275.
24. Morla AO, Mogford JE. 2000. Control of smooth muscle cell proliferation and phenotype by integrin signaling through focal adhesion kinase. Biochem Biophys Res Commun 272:298-302.
25. Mosse PRL, Campbell GR, Wang ZL, Campbell JH. 1985. Smooth muscle phenotypic expression in human carotid arteries. I: Comparison of cells from diffuse intimal thickening adjacent to atheromatous plaques with those of the media. Lab Invest 53:556-562.
26. Mott RF, Kirkwood TB, Curnow RN. 1990. Tests for the statistical significance of protein sequence similarities in data-bank seardres. Protein Eng 4:149-154.
27. Nakamura M, Edwin KJ, Inagami T. 1986. β-Adrenoceptor-mediated release of angiotensin II from mesenteric arteries. Am J Physiol 250:H144-H148.
28. Proudfoot D, Skepper JN, Shanahan CM, Weissberg PL. 1998. Calcification of Human vascular cells in vitro is correlated with high levels of matrix Gla protein and low levels of osteopontin expression. Arterioscler Thromb Vasc Biol 18:379-388.
29. Ruoslahti E. 1988. Fibronectin and its receptors. Annu Rev Biochem 57:375-413.
30. Salvesen G, Farley D, Shuman J, Przybyla A, Reilly C, Travis J. 1987. Molecular cloning of human cathepsin G: Structural similarity to mast cell and cytotoxic T lymphocyte proteinases. Biochemistry 26:2289-2293.
31. Thyberg J, Blomgren K, Roy J, Tran PK, Hedin U. 1997. Phenotypic modulation of smooth muscle cells after arterial injury is associated with changes in the distribution of laminin and fibronectin. J Histochem Cytochem 45:837-846.
32. Tonnesen MG, Klempner MS, Austen KF, Wintroub BU. 1982. Identification of a human neutrophil angiotension II-generating protease as cathepsin G. J Clin Invest 69:25-30.
33. Weissberg PL, Cary NR, Shanahan CM. 1995. Gene expression and vascular smooth muscle cell phenotype. Blood Press Suppl 2:68-73.