Mutual interference of adenovirus infection and myc expression

Journal of Virology

Volumn 77, Issue 14, 2003, Pages 7936-7944

  Löhr, Kristina ^a   Hartmann, Oliver ^a   Schäfer, Helmut ^a   Dobbelstein, Matthias ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; VIRUS DNA;

ADENOVIRUS; ARTICLE; DNA MICROARRAY; EXPRESSED SEQUENCE TAG; GENETIC SCREENING; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; ONCOGENE MYC; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN STABILITY; STRAIN DIFFERENCE; TRANSCRIPTION REGULATION; VIRUS EXPRESSION; VIRUS INFECTION; VIRUS REPLICATION;

ADENOVIRUS E1A PROTEINS; ADENOVIRUSES, HUMAN; CELL LINE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENES, MYC; HELA CELLS; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEINS; PROTO-ONCOGENE PROTEINS C-MYC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VIRUS REPLICATION;

EID: 0038758942     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.14.7936-7944.2003     Document Type: Article

References (48)

1. Amati, B., S. R. Frank, D. Donjerkovic, and S. Taubert. 2001. Function of the c-Myc oncoprotein in chromatin remodeling and transcription. Biochim. Biophys. Acta 1471:M135-M145.
2. Babiss, L. E., H. S. Ginsberg, and J. E. Darnell, Jr. 1985. Adenovirus E1B proteins are required for accumulation of late viral mRNA and for effects on cellular mRNA translation and transport. Mol. Cell. Biol. 5:2552-2558.
3. Beltz, G. A., and S. J. Flint. 1979. Inhibition of HeLa cell protein synthesis during adenovirus infection. Restriction of cellular messenger RNA sequences to the nucleus. J. Mol. Biol. 131:353-373.
4. Brazma, A., P. Hingamp, J. Quackenbush, G. Sherlock, P. Spellman, C. Stoeckert, J. Aach, W. Ansorge, C. A. Ball, H. C. Causton, T. Gaasterland, P. Glenisson, F. C. Holstege, I. F. Kim, V. Markowitz, J. C. Matese, H. Parkinson, A. Robinson, U. Sarkans, S. Schulze-Kremer, J. Stewart, R. Taylor, J. Vilo, and M. Vingron. 2001. Minimum information about a microarray experiment (MIAME) - toward standards for microarray data. Nat. Genet. 29:365-371.
5. Breckenridge, D. G., and G. C. Shore. 2000. Regulation of apoptosis by E1A and Myc oncoproteins. Crit. Rev. Eukaryot. Gene Expr. 10:273-280.
6. Classon, M., M. Henriksson, J. Sumegi, G. Klein, M. L. Hammarskjold, and M. L. Hammaskjold. 1987. Elevated c-myc expression facilitates the replication of SV40 DNA in human lymphoma cells. Nature 330:272-274.
7. Contente, A., A. Dittmer, M. C. Koch, J. Roth, and M. Dobbelstein. 2002. A polymorphic microsatellite that mediates induction of PIG3 by p53. Nat. Genet. 30:315-320.
8. de Stanchina, E., M. E. McCurrach, F. Zindy, S. Y. Shieh, G. Ferbeyre, A. V. Samuelson, C. Prives, M. F. Roussel, C. J. Sherr, and S. W. Lowe. 1998. E1A signaling to p53 involves the p19(ARF) tumor suppressor. Genes Dev. 12:2434-2442.
9. Dion, P. A., J. Fleurent, D. Roberge, and J. M. Weber. 1992. Reduction of c-myc expression correlated with E1a expression but not with the transformed phenotype. Virus Res. 26:231-240.
10. Eisenman, R. N. 2001. Deconstructing myc. Genes Dev. 15:2023-2030.
11. Fessler, S. P., and C. S. Young. 1998. Control of adenovirus early gene expression during the late phase of infection. J. Virol. 72:4049-4056.
12. Fuchs, M., J. Gerber, R. Drapkin, S. Sif, T. Ikura, V. Ogryzko, W. S. Lane, Y. Nakatani, and D. M. Livingston. 2001. The p400 complex is an essential E1A transformation target. Cell 106:297-307.
13. Gallimore, P. H., and A. S. Turnell. 2001. Adenovirus E1A: remodelling the host cell, a life or death experience. Oncogene 20:7824-7835.
14. Haberberger, T. C., K. Kupfer, and J. E. Murphy. 2000. Profiling of genes which are differentially expressed in mouse liver in response to adenoviral vectors and delivered genes. Gene Ther. 7:903-909.
15. Halbert, D. N., J. R. Cutt, and T. Shenk. 1985. Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff. J. Virol. 56:250-257.
16. Hiebert, S. W., M. Lipp, and J. R. Nevins. 1989. E1A-dependent transactivation of the human MYC promoter is mediated by the E2F factor. Proc. Natl. Acad. Sci. USA 86:3594-3598.
17. Huang, M. M., and P. Hearing. 1989. Adenovirus early region 4 encodes two gene products with redundant effects in lytic infection. J. Virol. 63:2605-2615.
18. Jones, N., and T. Shenk. 1979. Isolation of adenovirus type 5 host range deletion mutants defective for transformation of rat embryo cells. Cell 17:683-689.
19. Kitaura, H., M. Shinshi, Y. Uchikoshi, T. Ono, S. M. Iguchi-Ariga, and H. Ariga. 2000. Reciprocal regulation via protein-protein interaction between c-Myc and p21(cip1/waf1/sdi1) in DNA replication and transcription. J. Biol. Chem. 275:10477-10483.
20. Koch, P., J. Gatfield, C. Löber, U. Hobom, C. Lenz-Stöppler, J. Roth, and M. Dobbelstein. 2001. Efficient replication of adenovirus despite the overexpression of active and non-degradable p53. Cancer Res. 61:5941-5947.
21. 1 exit and up-regulation of c-MYC. Proc. Natl. Acad. Sci. USA 98:4646-4651.
22. Leppard, K. N., and T. Shenk. 1989. The adenovirus E1B 55 kd protein influences mRNA transport via an intranuclear effect on RNA metabolism. EMBO J. 8:2329-2336.
23. Lipp, M., R. Schilling, and G. Bernhardt. 1989. Trans-activation of human MYC: the second promoter is target for the stimulation by adenovirus E1a proteins. Oncogene 4:535-541.
24. Liu, H. T., R. Baserga, and W. E. Mercer. 1985. Adenovirus type 2 activates cell cycle-dependent genes that are a subset of those activated by serum. Mol. Cell. Biol. 5:2936-2942.
25. Lutz, P., and C. Kedinger. 1996. Properties of the adenovirus IVa2 gene product, an effector of late-phase-dependent activation of the major late promoter. J. Virol. 70:1396-1405.
26. Lutz, W., J. Leon, and M. Eilers. 2002. Contributions of Myc to tumorigenesis. Biochim. Biophys. Acta 1602:61-71.
27. Matsuda, S., J. Rouault, J. Magaud, and C. Berthet. 2001. In search of a function for the TIS21/PC3/BTG1/TOB family. FEBS Lett. 497:67-72.
28. McMahon, S. B., H. A. Van Buskirk, K. A. Dugan, T. D. Copeland, and M. D. Cole. 1998. The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins. Cell 94:363-374.
29. Menssen, A., and H. Hermeking. 2002. Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes. Proc. Natl. Acad. Sci. USA 99:6274-6279.
30. Ornelles, D. A., and T. Shenk. 1991. Localization of the adenovirus early region 1B 55-kilodalton protein during lytic infection: association with nuclear viral inclusions requires the early region 4 34-kilodalton protein. J. Virol. 65:424-429.
31. Pilder, S., M. Moore, J. Logan, and T. Shenk. 1986. The adenovirus E1B-55K transforming polypeptide modulates transport or cytoplasmic stabilization of viral and host cell mRNAs. Mol. Cell. Biol. 6:470-476.
32. Rosahl, T., and W. Doerfler. 1992. Alterations in the levels of expression of specific cellular genes in adenovirus-infected and -transformed cells. Virus Res. 26:71-90.
33. Shenk, T. 1996. Adenoviridae: the viruses and their replication, p. 2111-2148. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Fields virology, 3rd ed., vol. 2. Lippincott-Raven Publishers, Philadelphia, Pa.
34. Smith, R. R., R. J. Huebner, W. P. Rowe, W. E. Schatten, and L. B. Thomas. 1956. Studies on the use of viruses in the treatment of carcinoma of the cervix. Cancer 9;1211-1218.
35. Smith-Mungo, L. I., and H. M. Kagan. 1998. Lysyl oxidase: properties, regulation and multiple functions in biology. Matrix Biol. 16:387-398.
36. Studzinski, G. P., U. T. Shankavaram, D. C. Moore, and P. V. Reddy. 1991. Association of c-myc protein with enzymes of DNA replication in high molecular weight fractions from mammalian cells. J. Cell. Physiol. 147:412-419.
37. Tauber, B., and T. Dobner. 2001. Adenovirus early E4 genes in viral oncogenesis. Oncogene 20:7847-7854.
38. Tauber, B., and T. Dobner. 2001. Molecular regulation and biological function of adenovirus early genes: the E4 ORFS. Gene 278:1-23.
39. Thalmeier, K., H. Synovzik, R. Mertz, E. L. Winnacker, and M. Lipp. 1989. Nuclear factor E2F mediates basic transcription and trans-activation by E1a of the human MYC promoter. Genes Dev. 3:527-536.
40. Tribouley, C., P. Lutz, A. Staub, and C. Kedinger. 1994. The product of the adenovirus intermediate gene IVa2 is a transcriptional activator of the major late promoter. J. Virol. 68:4450-4457.
41. Tusher, V. G., R. Tibshirani, and G. Chu. 2001. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. USA 98:5116-5121.
42. van Dam, H., R. Offringa, A. M. Smits, J. L. Bos, N. C. Jones, and A. J. van der Eb. 1989. The repression of the growth factor-inducible genes JE, c-myc and stromelysin by adenovirus E1A is mediated by conserved region 1. Oncogene 4:1207-1212.
43. Weigel, S., and M. Dobbelstein. 2000. The nuclear export signal within the E4orf6 protein of adenovirus type 5 supports virus replication and cytoplasmic accumulation of viral mRNA. J. Virol. 74:764-772.
44. Wienzek, S., and M. Dobbelstein. 2001. Viral and cellular factors that target the promyelocytic leukemia oncogenic domains strongly activate a glucocorticoid-responsive promoter. J. Virol. 75:5391-5397.
45. Yang, U. C., W. Huang, and S. J. Flint. 1996. mRNA export correlates with activation of transcription in human subgroup C adenovirus-infected cells. J. Virol. 70:4071-4080.
46. Yang, Y. H., S. Dudoit, P. Luu, D. M. Lin, V. Peng, J. Ngai, and T. P. Speed. 2002. Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res. 30:e15. [Online.] http://nar.oupjournals.org/cgi/content/full/30/4/e15.
47. Zaika, A., M. Irwin, C. Sansome, and U. M. Moll. 2001. Oncogenes induce and activate endogenous p73 protein. J. Biol. Chem. 276:11310-11316.
48. Zantema, A., and A. J. van der Eb. 1995. Modulation of gene expression by adenovirus transformation. Curr. Top. Microbiol. Immunol. 199:1-23.