Spontaneous aggregation and cytotoxicity of the β-amyloid Aβ1-40: A kinetic model

Journal of Protein Chemistry

Volumn 22, Issue 1, 2003, Pages 31-40

  Taylor, Bruce M ^a   Sarver, Ronald W ^a   Fici, Gregory ^a   Poorman, Roger A ^a   Lutzke, Barry S ^a   Molinari, Antonio ^a   Kawabe, Thomas ^a   Kappenman, Karl ^a   Buhl, Allen E ^a   Epps, Dennis E ^a  

^a PFIZER INC   (United States)

Author keywords

Aggregation; Alzheimer's; Amyloid peptide; Kinetics; Toxicity

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN [1-40]; ANTIBODY; CASPASE; GREEN FLUORESCENT PROTEIN; LACTATE DEHYDROGENASE; MONOMER; PEPTIDE; TETRAMER; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CELL DAMAGE; CIRCULAR DICHROISM; CYTOTOXICITY; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; KINETICS; OLIGOMERIZATION; POLARIZATION; PROTEIN AGGREGATION; TIME; TURBIDITY;

AMYLOID BETA-PROTEIN; ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; FLUORESCENCE POLARIZATION; HIPPOCAMPUS; HUMANS; KINETICS; NEURONS; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0038754071     PISSN: 02778033     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1023063626770     Document Type: Article

References (28)

1. Anderton, B. H., Callahan, L., Coleman, P., Davies, P., Flood, D., Jicha, G. A., et al. (1998). Prog. Neurobiol. 55: 595-609.
2. Ainsztein, A. M., and Purich, D. L. (1994). J. Biol. Chem. 269: 28465-28471.
3. Brewer, G. J., and Price, P. J. (1996). Neuroreport 7: 1509-1512.
4. Brewer, G. J., Torricelli, J. R., Evege, E. K., and Price, P. J. (1993). J. Neurosci. Res. 35: 567-576.
5. Cooper, J. A., Buhle, E. L., Jr., Walker, S. B., Tsong, T. Y., and Pollard, T. D. (1983). Biochemistry 22: 2193-2202.
6. Cummings, J. L., White, G. L., Jones, M. W., Cooper-Blacketer, D., Marshall, V. J., Irizarry, M., et al. (1999). Nat. Neurosci. 2: 271-276.
7. DeGrado, W. F., Musso, G. F., Lieber, M., Kaiser, E. T., and Kézdy, F. J. (1982). Biophys. J. 37: 329-338.
8. Findeis, M. A., Musso, G. M., Arico-Muendel, C. C., Benjamin, H. W., Hundal, A. M., Lee, J.-J., et al. (1999). Biochemistry 38: 6791-6800.
9. Ghanta, J., Shen, C.-L., Kiessling, L. L., and Murphy, R. M. (1996). J. Biol. Chem. 271: 29525-29528.
10. Hardy, J. (1997). Trends Neurosci. 20: 154-159.
11. Harper, J. D., and Lansbury, P. T., Jr. (1997). Annu. Rev. Biochem. 66: 385-407.
12. Hartley, D. M., Walsh, D. M., Ye, C. P., Diehl, T., Vasquez, S., Vassilev, P. M., et al. (1999). J. Neurosci. 19: 8876-8884.
13. Holmes, D. F., Chapman, J. A., Prockop, D. J., and Kadler, K. E. (1992). Proc. Natl. Acad. Sci. USA 89: 9855-9859.
14. Hsia, A. Y., Masliah, E., McConologue, G., Yu, G.-Q., Tatsuno, G., Hu, K., et al. (1999). Proc. Natl. Acad. Sci. USA 96: 3228-3233.
15. Jarrett, J. T., Berger, E. P., and Lansbury, P. T., Jr. (1993). Biochemistry 32: 4693-4697.
16. Kaiser, E. T., and Kézdy, F. J. (1984). Science 223: 249-255.
17. Kayed, R., Bernhagen, J., Greenfield, N., Sweimeh, K., Brunner, H., Voelter, W., et al. (1999). J. Mol. Biol. 287: 781-796.
18. Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., et al. (1998). Proc. Natl. Acad. Sci. USA 95: 6448-6453.
19. Lomakin, A., Chung, D. S., Benedek, G. B., Kirschner, D. A., and Teplow, D. B. (1996). Proc. Natl. Acad. Sci. USA 93: 1125-1129.
20. Naiki, H., and Nakakuki, K. (1996). Lab. Invest. 74: 374-382.
21. Pallitto, M. M., Ghanta, J., Heinzelman, P., Kiessling, L. L., and Murphy, R. M. (1999). Biochemistry 38: 3570-3578.
22. Pallitto, M. M., and Murphy, R. M. (2001). Biophys. J. 81: 1805-1822.
23. Pike, C. J., Burdick, D., Walencewicz, A. J., Glabe, C. G., and Cotman, C. W. (1993). J. Neurosci. 13: 1676-1687.
24. Pillot, T., Drouet, B., Quielle, S., Labeur, C., Vandekerckhove, J., Rosseneu, M., et al. (1999). J. Neurochem. 73: 1626-1639.
25. Tobacman, L. S., and Korn, E. D. (1983). J. Biol. Chem. 258: 3207-3214.
26. Voter, W. A., and Erickson, H. P. (1984). J. Biol. Chem. 259: 10430-10438.
27. Walsh, D. M., Hartley, D. M., Kusumoto, Y., Fezoui, Y., Condron, M. M., Lomakin, A., et al. (1999). J. Biol. Chem. 274: 25945-25952.
28. Zhu, Y. J., Lin, H., and Ratneshwar, L. (2000). FASEB J. 14: 1244-1254.