Cryo-thawed embryos obtained from conception cycles have double the implantation and pregnancy potential of those from unsucessful cycles

Human Reproduction

Volumn 18, Issue 6, 2003, Pages 1313-1318

  El Toukhy, T ^a   Khalaf, Y ^a   Al Darazi, K ^a   O'Mahony, F ^a   Wharf, E ^a   Taylor, A ^a   Braude, P ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

Cryo thawed cycle prognosis; Embryo cryopreservation; IVF outcome

Indexed keywords

BUSERELIN; CHORIONIC GONADOTROPIN; ESTRADIOL VALERATE; ESTROGEN; GONADOTROPIN; PROGESTERONE; RECOMBINANT FOLLITROPIN; UROFOLLITROPIN;

ADULT; ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONCEPTION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRYOPRESERVATION; EMBRYO; EMBRYO DEVELOPMENT; EMBRYO TRANSFER; FEMALE; FERTILIZATION; FERTILIZATION IN VITRO; FROZEN SECTION; HUMAN; INFERTILITY; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; MALE; NIDATION; OOCYTE; OVARY HYPERSTIMULATION; PREGNANCY; PREGNANCY RATE; PROGNOSIS; THAWING; TREATMENT OUTCOME;

EID: 0038745726     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/deg235     Document Type: Article

References (36)

1. Acosta, A., Oehninger, S., Hammer, J., Muasher, S.J., Liang, H.M. and Jones, D.L. (1990) Preclinical abortions: Incidence and significance in the Norfolk in vitro fertilization program. Fertil. Steril., 53, 673-676.
2. Barlow, P., Lejeune, B., Puissant, F., Englert, Y., Van Rysselberge, M., Degueldre, M., Vekemans, M. and Leroy, F. (1988) Early pregnancy loss and obstetric risk after in-vitro fertilization and embryo replacement. Hum. Reprod., 3, 671-675.
3. Bates, G.W. and Ginsburg, E.S. (2002) Early pregnancy loss in in vitro fertilization (IVF) is a positive predictor of subsequent IVF success. Fertil. Steril., 77, 337-341.
4. Campbell, M.J., Julious, S.A. and Altman, D.G. (1995) Estimating sample sizes for binary, ordered categorical, and continuous outcomes in two group comparisons. Br. Med. J., 311, 1145-1148.
5. Croucher, C.A., Lass, A., Margara, R. and Winston, R.M. (1998) Predictive value of the results of a first in-vitro fertilization cycle on the outcome of subsequent cycles. Hum. Reprod., 13, 403-408.
6. Edgar, D.H., Bourne, H., Speirs, A.L. and McBain, J.C. (2000) A quantitative analysis of the impact of cryopreservation on the implantation potential of human early cleavage stage embryos. Hum. Reprod., 15, 175-179.
7. Fisch, J.D., Milki, A.A. and Behr, B. (1999) Sibling embryo blastocyst development correlates with the in vitro fertilization day 3 embryo transfer pregnancy rate in patients under age 40. Fertil. Steril., 4, 750-752.
8. Fugger, E.F., Bustillo, M., Katz, L.P., Dorfmann, A.D., Bender, S.D. and Schulman, J.D. (1988) Embryonic development and pregnancy from fresh and cryopreserved sibling pronucleate human zygotes. Fertil. Steril., 50, 273-278.
9. Gerris, J., De Neubourg, D., Mangelschots, K., Van Royen, E., Van De Meerssche, M. and Valkenburg, M. (1999) Prevention of twin pregnancy after in-vitro fertilization or intracytoplasmic sperm injection based on strict embryo criteria: A prospective randomized clinical trial. Hum. Reprod., 14, 2581-2587.
10. Guerif, F., Bidault, R., Cadoret, V., Couet, M., Lansac, J. and Royere, D. (2002) Parameters guiding selection of best embryos for transfer after cryopreservation: A reappraisal. Hum. Reprod., 17, 1321-1326.
11. Karlstrom, P.O., Bergh, T., Forsberg, A.S., Sandkvist, U. and Wikland, M. (1997) Prognostic factors for the success rate of embryo freezing. Hum. Reprod., 12, 1263-1266.
12. Kondo, I., Suganuma, N., Ando, T., Asada, Y., Furuhashi, M. and Tomoda, Y. (1996) Clinical factors for successful cryopreserved-thawed embryo transfer. J. Assist. Reprod. Genet., 13, 201-206.
13. Lassalle, B., Testart, J. and Renard, J.P. (1985) Human embryo features that influence the success of cryopreservation with the use of 1,2-propanediol. Fertil. Steril., 44, 645-651.
14. Laverge, H., Van Der Elst, J., De Sutter, P., Verschraegen-Spae, M.R., De Paepe, A. and Dhont, M. (1998) Fluorescent in-situ hybridization on human embryos showing cleavage arrest after freezing and thawing. Hum. Reprod., 13, 425-429.
15. Levy, T., Dicker, D., Ashkenazi, J., Feldberg, D., Shelef, M. and Goldman, J.A. (1991) The prognostic value and significance of pre-clinical abortions in in-vitro fertilization-embryo transfer programs. Fertil. Steril., 56, 71-74.
16. Lightman, A., Kol, S., Wayner, V., Vertman, D., Manor, D. and Itskovitz-Eldor, T. (1997) The presence of a sponsoring embryo in a batch of poor quality thawed embryos significantly increases pregnancy and implantation rate. Fertil. Steril., 67, 711-716.
17. Lin, Y.P., Cassidenti, D.L., Chacon, R.R., Soubra, S.S., Rosen, G.F. and Yee, B. (1995) Successful implantation of frozen sibling embryos is influenced by the outcome of the cycle from which they were derived. Fertil. Steril., 63, 262-267.
18. Mandelbaum, J., Junca, A.M., Plachot, M., Alnot, M.O., Salat-Baroux, J., Alvarez, S., Tibi, C., Cohen, J., Debache, C. and Tesquier, L. (1988) Cryopreservation of human embryos and oocytes. Hum. Reprod., 3, 117-119.
19. Martikainen, H., Tiitinen, A., Tomas, C., Tapanainen, J., Orava, M., Tuomivaara, L., Vilska, S., Hyden-Granskog, C., Hovatta, O. and the Finnish ET Study Group. (2001) One versus two embryo transfer after IVF and ICSI: A randomized study. Hum. Reprod., 16, 1900-1903.
20. Molloy, D., Doody, M.L. and Breen, T. (1995) Second time around: A study of patients seeking second assisted reproduction pregnancies. Fertil. Steril., 64, 546-551.
21. Oehninger, S., Mayer, J. and Muasher, S. (2000) Impact of different clinical variables on pregnancy outcome following embryo cryopreservation. Mol. Cell. Endocrinol., 169, 73-77.
22. Schalkoff, M.E., Oskowitz, S.P. and Powers, R.D. (1993) A multifactorial analysis of the pregnancy outcome in a successful embryo cryopreservation program. Fertil. Steril., 59, 1070-1074.
23. Selick, C.E., Hofmann, G.E., Albano, C., Horowitz, G.M., Copperman, A.B., Garrisi, G.J. and Navot, D. (1995) Embryo quality and pregnancy potential of fresh compared with frozen embryos - Is freezing detrimental to high quality embryos? Hum. Reprod., 10, 392-395.
24. Simon, A., Ronit, C., Lewin, A., Mordel, N., Zajicek, G. and Laufer, N. (1993) Conception rate after in vitro fertilization in patients who conceived in a previous cycle. Fertil. Steril., 59, 343-347.
25. Staessen, C., Camus, M., Bollen, N., Devroey, P. and Van Steirteghem, A.C. (1992) The relationship between embryo quality and the occurrence of multiple pregnancies. Fertil. Steril., 57, 626-630.
26. Steer, C.V., Mills, C.L., Tan, S.L., Campbell, S. and Edwards, R.G. (1992) The cumulative embryo score: A predictive embryo scoring technique to select the optimal number of embryos to transfer in an in-vitro fertilization and embryo transfer programme. Hum. Reprod., 7, 117-119.
27. Tan, S.L., Doyle, P., Maconochie, N., Edwards, R.G., Balen, A., Bekir, J., Brindsen, P. and Campbell, S. (1994) Pregnancy and birth rates of live infants after in vitro fertilization in women with an without previous in vitro fertilization pregnancies: A study of eight thousand cycles at one center. Am. J. Obstet. Gynecol., 170, 34-40.
28. Templeton, A. and Morris, J.K. (1998) Reducing the risk of multiple births by transfer of two embryos after in vitro fertilization. N. Engl. J. Med., 339, 573-577.
29. Templeton, A., Morris, J.K. and Parslow, W. (1996) Factors that affect outcome of in-vitro fertilisation treatment. Lancet, 348, 1402-1406.
30. Tiitinen, A., Halttunen, M., Harkki, P., Vuoristo, P. and Hyden-Granskog, C. (2001) Elective single embryo transfer: The value of cryopreservation. Hum. Reprod., 16, 1140-1144.
31. Toner, J.P., Veeck, L.L., Acosta, A.A. and Muasher, S.J. (1991) Predictive value of pregnancy during original in vitro fertilization cycle on implantation and pregnancy in subsequent cryothaw cycles. Fertil. Steril., 56, 505-508.
32. Trounson, A. (1986) Preservation of human eggs and embryos. Fertil. Steril., 46, 1-12.
33. Van Der Elst, J., Van Den Abbeel, E., Vitrier, S., Camus, M., Devroey, P. and Van Steirteghem, A.C. (1997) Selective transfer of cryopreserved human embryos with further cleavage after thawing increases delivery and implantation rates. Hum. Reprod., 12, 1513-1521.
34. Van Royen, E., Mangelschots, K., De Neubourg, D., Valkenburg, M., Vander Meerssche, M., Ryckaert, G., Eestermans, W. and Gerris, J. (1999) Characterization of a top quality embryo, a step towards single-embryo transfer. Hum. Reprod., 14, 2345-2349.
35. Wang, J.X., Yap, Y.Y. and Matthews, C.D. (2001) Frozen - Thawed embryo transfer: Influence of clinical factors on implantation rate and risk of multiple conception. Hum. Reprod., 16, 2316-2319.
36. Ziebe, S., Bech, B., Petersen, K., Mikkelsen, A.L., Gabrielsen, A. and Nyboe Andersen, A. (1998) Resumption of mitosis during post-thaw culture: A key parameter in selecting the right embryos for transfer. Hum. Reprod., 13, 178-181.