Estimation of linkage and association from Allele transmission data

Biometrical Journal

Volumn 45, Issue 3, 2003, Pages 349-366

  Malley, James D ^c   Redner, Richard A ^a   Severini, Thomas A ^c   Badner, Judith A ^b   Pajevic, Sinisa ^c   Bailey Wilson, Joan E ^c  

^a UNIVERSITY OF TULSA   (United States)

^b The University of Chicago   (United States)

^c NONE

Author keywords

Association; Integrated likelihood; Linkage; Parameter estimation; TDT

Indexed keywords

GENES; MEAN SQUARE ERROR; STATISTICAL TESTS;

CONFIDENCE INTERVAL; HYPOTHESIS TESTS; INTEGRATED LIKELIHOOD; LINKAGE; LINKAGE DISEQUILIBRIUM; PARAMETERS ESTIMATION; PARAMETRIC MODELS; TDT; TEST STATISTICS; TRANSMISSION DATA;

PARAMETER ESTIMATION;

EID: 0038739448     PISSN: 03233847     EISSN: None     Source Type: Journal    
DOI: 10.1002/bimj.200390017     Document Type: Article

References (20)

1. ABEL, L. and MÜLLER-MYHSOK, B., 1998: Maximum-likelihood expression for the transmission/disequilibrium test and power considerations. American Journal of Human Genetics, 63, 664-667.
2. BERGER, J., LISEO, B., and WOLPERT, R., 1999: Integrated likelihood methods for eliminating nuisance parameters. Statistical Science, 14, 1-28.
3. CARLIN, B. and LOUIS, T., 2000: Bayes and Empirical Bayes Methods for Data Analysis. 2nd Edition. Chapman & Hall.
4. CORDELL, H. and CARPENTER, J., 2000: Bootstrap confidence intervals for relative risk parameters in affected-sib-pair data. Genetic Epidemiology, 18, 157-172.
5. CORDELL, H., ELSTON, R., 1999: Fieller's theorem and linkage disequilibrium mapping. Genetic Epidemiology, 17, 237-252.
6. GELMAN, A., CARLIN, J., STERN, and H., RUBIN, D., 1995: Bayesian Data Analysis. Chapman & Hall.
7. GOLDSTEIN, D., 1995: Asymptotic distributions of polylocus test statistics. Genetic Epidemiology, 12, 195-202.
8. KNAPP, M., 1999: The transmission/disequilibrium test and parental-genotype reconstruction: the reconstruction-combined transmission/disequilibrium test. American Journal of Human Genetics, 64, 861-870.
9. POST, S. and WHITEHOUSE, P. (editors), 1998. Genetic Testing for Alzheimer Disease; Ethical and Clinical Issues. Johns Hopkins Press.
10. SCHAID, D., 1996: General score tests for associations of genetic markers with disease using cases and their parents. Genetic Epidemiology, 13, 423-449.
11. SCHAID, D., 1998: Transmission disequilibrium, family controls, and great expectations. American Journal of Human Genetics, 63, 935-941.
12. SCHAID, D., 1999: Case-Parent design for gene-environment interaction. Genetic Epidemiology, 16, 261-273.
13. SELF, S. and LIANG, K., 1987: Asymptotic properties of maximum likelihood estimators and likelihood ratio tests under nonstandard conditions. Journal of the American Statistical Association, 82, 605-610.
14. SEVERINI, T., 2000: Likelihood Methods in Statistics. Oxford University Press.
15. SHAM, P., 1998: Statistics in Human Genetics. Wiley & Sons.
16. SHAM, P. and CURTIS, D., 1995: An extended transmission/disequilibrium test (TDT) for multi-allele marker loci. Annals of Human Genetics, 59, 323-336.
17. SPIELMAN, R., McGINNIS, R., and EWENS, W., 1993: Transmission test for diabetes mellitus (IDDM). American Journal of Human Genetics, 52, 506-516.
18. SPIELMAN, R., McGINNIS, R., and EWENS, W., 1994: The transmission/disequilibrium test detects cosegregation and linkage. American Journal of Human Genetics, 54, 559-560.
19. WHITTAKER, J., DENHAM, M., and MORRIS, A., 2000: The problems of using the transmission/disequilibrium test to infer tight linkage. American Journal of Human Genetics, 67, 523-526.
20. WILSON, S., 1997: On extending the transmission/disequilibrium test (TDT). Annals of Human Genetics, 61, 151-161.