Bootstrap confidence intervals for relative risk parameters in affected- sib-pair data

Genetic Epidemiology

Volumn 18, Issue 2, 2000, Pages 157-172

  Cordell, Heather J ^a,c   Carpenter, James R ^b  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c METROHEALTH MEDICAL CENTER   (United States)

Author keywords

Diabetes; IDDM; Lod score; Model free; Resampling

Indexed keywords

ARTICLE; CONTROLLED STUDY; GENETIC SUSCEPTIBILITY; INTERMETHOD COMPARISON; RELIABILITY; RISK ASSESSMENT; SAMPLE; SIBLING; SIMULATION; STATISTICAL ANALYSIS;

CONFIDENCE INTERVALS; DIABETES MELLITUS, TYPE 1; DISEASE SUSCEPTIBILITY; GENETIC DISEASES, INBORN; HUMANS; LIKELIHOOD FUNCTIONS; MODELS, GENETIC; RISK;

EID: 0033951876     PISSN: 07410395     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2272(200002)18:2<157::AID-GEPI5>3.0.CO;2-W     Document Type: Article

References (19)

1. Carpenter JR. 1998. Bootstrap likelihood ratio confidence intervals. J Appl Stat 25:647-57.
2. Carpenter JR. 1999. Test-inversion bootstrap confidence intervals. J R Stat Soc Series B 61:159-72.
3. Carpenter JR, Bithell J. Bootstrap confidence intervals: When? Which? What? A practical guide for medical statisticians. Stat Med (in press).
4. Cordell HJ, Olson JM. 1997. Confidence intervals for relative risk estimates from affected sib pair data. Genet Epidemiol 14:593-8.
5. Cordell HJ, Olson JM. Correcting for ascertainment bias of relative risk estimates obtained using affected-sib-pair linkage data. Genet Epidemiol (in press).
6. Davies JL, Kawaguchi Y, Bennett ST, Copeman JB, Cordell HJ, Pritchard LE, Reed PW, et al. 1994. A genome-wide search for human type 1 diabetes susceptibility genes. Nature 371:130-6.
7. Davison AC, Hinkley DV. Bootstrap methods and their applications. Cambridge: Cambridge University Press; 1997.
8. Efron B. 1981. Nonparametric standard errors and confidence intervals (with discussion). Cam J Statis 9:139-72.
9. Efron B. The jackknife, the bootstrap and other resampling plans. Philadelphia: Society for Industrial and Applied Mathematics; 1982.
10. Efron B. 1987. Better bootstrap confidence intervals. J Am Statist Assoc 82:171-200.
11. Efron B, Tibshirani R. An introduction to the bootstrap. New York: Chapman and Hall; 1993.
12. Haseman JK, Elston RC. 1972. The investigation of linkage between a quantitative trait and a marker locus. Behav Genet 2:3-19.
13. Holmans P. 1993. Asymptotic properties of affected-sib-pair linkage analysis. Am J Hum Genet 52:362-74.
14. Hugot J-P, Laurent-Puig P, Gower-Rousseau C, Olson JM, Lee JC, Beaugerie L, Naom I et al. 1996. Mapping of a susceptibility locus for Crohn's disease on chromosome 16 by a genome-wide non-parametric linkage analysis. Nature 379:821-3.
15. Lange K, Weeks DE, Boehnke M. 1988. Programs for Pedigree Analysis: MENDEL, FISHER, and dGENE. Genet Epidemiol 5:471-72.
16. Mein CA, Esposito L, Dunn MG, Johnson GCL, Timms AE, Goy JV, Smith AN, Sebag-Montefiore L, Merriman ME, Wilson AJ, Pritchard LE, Cucca F, Barnett AH, Bain SC, Todd JA. 1998. A search for type 1 diabetes susceptibility genes in families from the United Kingdom. Nature Genet 19:297-300.
17. Olson JM, Cordell HJ. Ascertainment bias in the estimation of sibling genetic risk parameters. Genet Epidemiol (in press).
18. Risch N. 1990. Linkage strategies for genetically complex traits. II. The power of affected relative pairs. Am J Hum Genet 46:229-41.
19. Tibshirani R. 1988. Variance stabilisation and the bootstrap. Biometrika 75:433-44.