Ischemic preconditioning and nicotinamide in spinal cord protection in an experimental model of transient aortic occlusion

European Journal of Cardio-thoracic Surgery

Volumn 23, Issue 6, 2003, Pages 1028-1033

  Isbir, C Selim ^a,d   Ak, Koray ^a   Kurtkaya, Ozlem ^a   Zeybek, Ümit ^b   Akgün, Serdar ^a   Scheitauer, Bernd W ^c   Sav, Aydin ^a   Cobanoglu, Adnan ^a  

^a MARMARA UNIVERSITY   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

^c MAYO CLINIC   (United States)

^d NONE   (Turkey)

Author keywords

Aortic injury; Apoptosis; Spinal cord

Indexed keywords

NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ANIMAL MODEL; ANIMAL TISSUE; AORTA CLAMPING; AORTA OCCLUSION; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; GENERAL ANESTHESIA; HEART INFARCTION PREVENTION; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MORTALITY; NERVE CELL NECROSIS; NEUROLOGIC EXAMINATION; NONHUMAN; PARAPLEGIA; PRIORITY JOURNAL; RAT; SCORING SYSTEM; SPINAL CORD ATROPHY;

ANIMALS; AORTIC ANEURYSM; APOPTOSIS; ENERGY METABOLISM; INFUSIONS, INTRA-ARTERIAL; ISCHEMIC PRECONDITIONING; MODELS, ANIMAL; NIACINAMIDE; PARAPLEGIA; POSTOPERATIVE COMPLICATIONS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SPINAL CORD;

EID: 0038724551     PISSN: 10107940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1010-7940(03)00110-6     Document Type: Article

References (22)

1. Svensson L.G., Crawford E.S., Hess K.R., Coselli J.S., Safi H.J. Experience with 1509 patients undergoing thoracoabdominal aortic operations. J Vasc Surg. 17:1993;350-370.
2. Wadouh F., Arndt C.F., Metzger H., Hartmann M., Wadouh R., Borst H.G. Direct measurements of oxygen tension on the spinal cord surface of pigs after occlusion of the descending aorta. J Thorac Cardiovasc Surg. 89:1985;787-794.
3. Barone G.W., Joob A.W., Flanagan T.L., Dunn C.E., Kron I.L. The effect of hyperemia on spinal cord function after temporary thoracic aortic occlusion. J Vasc Surg. 8:1998;535-540.
4. Lim K.H., Connolly M., Rose D., Siegman F., Jacobowitz I., Acinapura A., Cunningham J.N. Jr. Prevention of reperfusion injury of the spinal cord: use of recombinant superoxide dismutase. Ann Thorac Surg. 42:1986;282-286.
5. Salzano R.P., Ellison L.H., Altonji P.F., Richter J., Deckers P.J. Regional deep hypothermia of the spinal cord protects against ischemic injury during thoracic aortic cross-clamping. Ann Thorac Surg. 57:1994;65-71.
6. Svensson L.G., Von Ritter C.M., Groeneveld H.T., Rickards E.S., Hunter S.J., Robinson M.F., Hinder R.A. Cross-clamping of the thoracic aorta: influence of aortic shunts, papaverine, calcium channel blocker, allopurinol, and superoxide dismutase on spinal cord blood flow and paraplegia in baboons. Ann Thorac Surg. 204:1986;38-47.
7. Matsuyama K., Chiba Y., Ihaya A., Kimura T., Tanigawa N., Muraoka R. Effect of spinal cord preconditioning on paraplegia during cross-clamping of the thoracic aorta. Ann Thorac Surg. 63:1997;1315-1320.
8. Zvara D.A., Colonna D.M., Deal D.D., Vernon J.C., Gowda M., Lundnell J.C. Ischemic preconditioning reduces neurologic injury in a rat model of spinal cord ischemia. Ann Thorac Surg. 68:1999;874-880.
9. Abraham S.V., Swain J.A., Forgash A.J., Williams B.L., Musulin M.M. Ischemic preconditioning protects against paraplegia after transient aortic occlusion in the rat. Ann Thorac Surg. 69:2000;475-479.
10. Rokkas C.K., Helfrich L.R., Lobner D.C., Choi D.W., Kouchoukos N.T. Dextrorphan inhibits the release of excitatory amino acids during spinal cord ischemia. Ann Thorac Surg. 58:1994;312-319.
11. Lang-Ladzunski L., Heurteaux C., Mignon A., Mantz J., Widmann C., Desmonts J.M., Ladzunski M. Ischemic spinal cord injury induced by aortic cross-clamping: prevention by riluzole. Eur J Cardiothorac Surg. 18:2000;174-181.
12. Lang-Ladzunski L., Bachet J. Pharmacological spinal cord protection with magnesium during replacement of the thoracic and thoracoabdominal aorta. Ann Thorac Surg. 72:2003? 2180-2181.
13. Ayoub I.A., Lee J.E., Ogilvy C.S., Beal F.M., Maynard K.I. Nicotinamide reduces infarction up to 2 h after the onset of permanent focal cerebral ischemia in Wistar rats. Neurosci Lett. 259:1999;21-24.
14. Tarlov I.M. Spinal cord compression: mechanism of paralysis and treatment. 1957;Charles C.Thomas, Springfield, IL.
15. Garcia J.H., Kamijyo Y. Cerebral infarct evaluation of histopathological changes after occlusion of a middle cerebral artery in primates. J Neuropathol Exp Neurol. 33:1974;408-421.
16. Rexed B. The cytoorchitectonic organisation of the spinal cord in the cat. J Comp Neurol. 96:1952;415-485.
17. Kroll K., Schrader J., Piper H.M., Henrich M. Release of adenosine and cyclic AMP from coronary endothelium in isolated guinea pig hearts: relation to coronary flow. Circ Res. 60:1987;659-665.
18. Kato H., Kanellopoulos G.K., Matsuo S., Wu Y.J., Jacquin M.F., Hsu C.Y., Choi D.W., Kouchoukos N.T. Protection of rat spinal cord from ischemia with dextrorphan and cyclohexemide: effects on necrosis and apoptosis. J Thorac Cardiovasc Surg. 114:1997;609.
19. Zhou Y., Zhao Y.N., Yang E.B., Ling E.A., Wang Y., Hassouna M.M., Mack P. Induction of neuronal and inducible nitric oxide synthase in the motoneurons of spinal cord following transient abdominal aorta occlusion in rats. J Surg Res. 87:(2):1999;185-193.
20. Lang-Ladzunski L., Matsushita K., Hirt L., Waeber C., Vonsattel J.P.G., Moskowitz M.A. Spinal cord ischemia development of a model in the mouse. Stroke. 31:2000;208-213.
21. Van Winkle D.M., Thornton J.D., Downey D.M., Downey J.M. The natural history of preconditioning: cardioprotection depends on duration of transient ischemia and time to subsequent ischemia. Coron Artery Dis. 2:1991;613-619.
22. Fan T., Wang C.C., Wang F.M., Cheng F., Qiao H., Liu S.L., Guo W., Xiang F.Y. Experimental study of ischemic preconditioning to spinal cord ischemia. Surg Neurol. 52:(3):1999;299-305.