Assessment of upper airway stabilizing forces with the use of phrenic nerve stimulation in conscious humans

Journal of Applied Physiology

Volumn 94, Issue 6, 2003, Pages 2289-2295

  Sériès, Frédéric ^a   Éthier, Germain ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Airway closure; Upper airway dilator muscles; Upper airway stability

Indexed keywords

ADULT; AIRWAY PRESSURE; AIRWAY RESISTANCE; ARTICLE; BREATHING; CONTROLLED STUDY; CORRELATION ANALYSIS; DYNAMICS; EXPIRATORY FLOW; HUMAN; HUMAN EXPERIMENT; INSPIRATORY CAPACITY; MALE; MUSCLE TWITCH; NERVE STIMULATION; NORMAL HUMAN; PHRENIC NERVE; PRIORITY JOURNAL; WAKEFULNESS;

EID: 0038701951     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00924.2002     Document Type: Article

References (41)

1. Brancatisano TP, Collett PW, and Engel LA. Factors influencing glottic dimensions during forced expiration. J Appl Physiol 55: 1825-1829, 1983.
2. Brennick MJ, Parisi RA, and England SJ. Influence of preload and afterload on genioglossus muscle length in awake goats. Am J Respir Crit Care Med 155: 2010-2017, 1997.
3. Brennick MJ, Parisi RA, and England SJ. Genioglossal length and EMG responses to static upper airway pressures during hypercapnia in goats. Respir Physiol 127: 227-239, 2001.
4. Burnham KP and Anderson RD. Model Selection and Inference. A Practical Information -Theoretic Approach. New York: Springer-Verlag, 1998, chapts. 22 and 24, p. 43-48, 51-54.
5. Goh AS, Issa FG, and Sullivan CE. Upper airway dilating forces during wakefulness and sleep in dogs. J Appl Physiol 61: 2148-2155, 1986.
6. Gottfried SB, Strohl KP, Van De Graaff W, Fouke JM, and Dimarco AF. Effects of phrenic nerve stimulation on upper airway resistance in anesthetized dogs. J Appl Physiol 55: 419-426, 1983.
7. Hudgel DW and Harasick T. Fluctuation in timing of upper airway and chest wall inspiratory muscle activity in obstructive sleep apnea. J Appl Physiol 69: 443-450, 1990.
8. Hudgel DW and Hendricks C. Palate and hypopharynx sites of inspiratory narrowing of upper airway during sleep. Am Rev Respir Dis 138: 1542-1547, 1988.
9. Kuna S and Brennick MJ. Effects of pharyngeal muscle activation on airway pressure-area relationships. Am J Respir Crit Care Med 166: 972-977, 2002.
10. Kuna S and Remmers JE. Neural and anatomic factors related to upper airway occlusion during sleep. Med Clin North Am 69: 1221-1242, 1985.
11. Kuna ST and Smickley JS. Superior pharyngeal constrictor activation in obstructive sleep apnea. Am J Respir Crit Care Med 156: 874-880, 1997.
12. Kuna ST and Vanoye CR. Mechanical effects of pharyngeal constrictor activation on pharyngeal airway function. J Appl Physiol 86: 411-417, 1999.
13. Leiter JC. Upper airway shape. Is it important in the pathogenesis of obstructive sleep apnea? Am J Respir Crit Care Med 153: 894-898, 1996.
14. Mador MJ, Rodis A, Magalang UJ, and Ameen K. Comparison of cervical magnetic and transcutaneous phrenic nerve stimulation before and after threshold loading. Am J Respir Crit Care Med 154: 448-453, 1996.
15. Mardia KV. Applications of some measures of multivariate skewness and kurtosis in testing normality and robustness studies. Sankhya B 36: 115-128, 1974.
16. Meurice JC, Marc I, Carrier G, and Sériès F. Effects of mouth opening on upper airway collapsibility in normal sleeping subjects. Am J Respir Crit Care Med 153: 255-259, 1996.
17. Mezzanotte WS, Tangel DJ, and White DP. Influence of sleep onset on upper airway muscle activity in apnea aptients versus normal controls. Am J Respir Crit Care Med 153: 1880-1887, 1996.
18. Mills GH, Kyroussis D, Hamnegard CH, Polkey MI, Green M, and Moxham J. Bilateral magnetic stimulation of the phrenic nerves from an anterolateral approach. Am J Respir Crit Care Med 154: 1099-1105, 1996.
19. 2 rebreathing in humans. J Appl Physiol 50: 1052-1055, 1981.
20. Remmers JE, Degroot WJ, Sauerland EK, and Anch AM. Pathogenesis of upper airway occlusion during sleep. J Appl Physiol 44: 931-938, 1978.
21. Sanfaçon C, Marc I, and Sériès F. Usefulness of phrenic nerve stimulation to measure upper airway collapsibility in normal awake subjects. Respir Physiol 130: 57-67, 2002.
22. Schwab RJ, Gefter WB, Hoffman EA, Gupta KB, and Pack AR. Dynamic upper airway imaging during awake respiration in normal subjects and patients with sleep disordered breathing. Am Rev Respir Dis 148: 1385-1400, 1993.
23. Schwartz AR, O'Donnell CP, Baron J, Schubert N, Alam D, Samadi SD, and Smith PL. The hypotonic upper airway in obstructive sleep apnea. Am J Respir Crit Care Med 157: 1051-1057, 1998.
24. Sériès F, Coté C, Simoneau JA, Gélinas Y, St Pierre S, Leclerc J, Ferland R, and Marc I. Physiologic and metabolic profile of musculus uvulae in sleep apnea syndrome and in snorers. J Clin Invest 95: 20-25, 1995.
25. Sériès F, Côté C, and St. Pierre S. Dysfunctional mechanical coupling of upper airway tissues in sleep apnea syndrome. Am J Respir Crit Care Med 159: 1551-1555, 1999.
26. Sériès F, Demoule A, Marc I, Sanfagon C, Derenne JP, and Similowski T. Inspiratory flow dynamics during phrenic nerve stimulation in awake normals. Am J Respir Crit Care Med 160: 614-620, 1999.
27. Sériès F and Ethier G. Site of phrenic nerve stimulation-upper airway collapse: influence of expiratory time. J Appl Physiol 92: 665-671, 2002.
28. Sériès F and Marc I. Effects of lung volume on upper airway collapsibility in normal awake subjects. J Appl Physiol 75: 1222-1225, 1993.
29. Sériès F and Marc I. Influence of genioglossus tonic activity on upper airway dynamics assessed by phrenic nerve stimulation. J Appl Physiol 92: 418-423, 2002.
30. Sériès F, Straus C, Demoule A, Attali V, Arnulf I, Derenne JP, and Similowski T. Assessment of upper airway dynamics in awake sleep apnea patients with phrenic nerve stimulation. Am J Respir Crit Care Med 162: 795-800, 2000.
31. Similowski T, Fleury B, Launois S, Cathala HP, Bouche P, and Derenne JP. Cervical magnetic stimulation: a new painless method for bilateral phrenic nerve stimulation in conscious humans. J Appl Physiol 67: 1311-1318, 1989.
32. Smith J and Bellemare F. Effect of lung volume on in vivo contraction characteristics of human diaphragm. J Appl Physiol 62: 1893-1900, 1987.
33. Strohl KP, Hensley MJ, Hallett M, Saunders NA, and Ingram RH. Activation of upper airway muscles before onset of inspiration in normal humans. J Appl Physiol 49: 638-642, 1980.
34. Strohl KP, Wolin AD, Van Lunteren E, and Fouke JM. Assessment of muscle action on upper airway stability in anesthetized dogs. J Lab Clin Med 110: 221-230, 1987.
35. Thut DC, Schwartz AR, Roach D, Wise RA, Permutt S, and Smith PL. Tracheal and neck position influence upper airway airflow dynamics by altering airway length. J Appl Physiol 75: 2084-2090, 1993.
36. Van De Graaff WB. Thoracic influence of upper airway patency. J Appl Physiol 65: 2124-2131, 1988.
37. Van Der Touw T, O'Neill N, Amis T, Wheatley J, and Brancatisano A. Soft palate muscle activity in response to hypoxic hypercapnia. J Appl Physiol 77: 2600-2605, 1994.
38. Van Lunteren E, Haxiu MA, and Cherniack NS. Respiratory changes in nasal muscle length. J Appl Physiol 59: 453-458, 1985.
39. Van Lunteren E, Van de Graaff W, Parker DM, Strohl KP, Mitra J, Salomone J, and Cherniack NS. Activity of upper airway muscles during augmented breaths. Respir Physiol 53: 87-98, 1983.
40. Vérin E, Sériès F, Locher CF, Straus C, Zelter M, Derenne JP, and Similowski T. Effects of neck flexion and mouth opening on inspiratory flow dynamics in awake man. J Appl Physiol 92: 84-92, 2002.
41. Woodall DL, Horanson JA, and Mathew OP. Time of application of negative pressure pulses and upper airway muscle activity. J Appl Physiol 67: 366-370, 1998.