Synthesis of 4-(5-iodo-3-methylpyrazolyl) phenylsulfonamide and its elaboration to a COX II inhibitor library by solution-phase Suzuki coupling using Pd/C as a solid-supported catalyst

Journal of Combinatorial Chemistry

Volumn 5, Issue 2, 2003, Pages 118-124

  Organ, Michael G ^a   Mayer, Stanislas ^a  

^a YORK UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 (5 IODO 3 METHYLPYRAZOLYL)PHENYLSULFONAMIDE; CARBON; CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; IODINE DERIVATIVE; PALLADIUM; UNCLASSIFIED DRUG; 4-(5-IODO-3-METHYLPYRAZOLYL)PHENYLSULFONAMIDE; CYCLOOXYGENASE 2; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; IODIDE; ISOENZYME; PROSTAGLANDIN SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; PYRAZOLE DERIVATIVE; SULFONAMIDE;

ARTICLE; CATALYST; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; OXIDATION; SOLID; SUZUKI COUPLING REACTION; CATALYSIS; CHEMISTRY; DRUG EFFECT; ELECTROSPRAY MASS SPECTROMETRY; OXIDATION REDUCTION REACTION; SYNTHESIS;

CATALYSIS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; INDICATORS AND REAGENTS; IODIDES; ISOENZYMES; OXIDATION-REDUCTION; PALLADIUM; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PYRAZOLES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SULFONAMIDES;

EID: 0038700568     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc020045r     Document Type: Article

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