Clinical review 89: Small as fetus and short as child - From endogenous to exogenous growth hormone

Journal of Clinical Endocrinology and Metabolism

Volumn 82, Issue 7, 1997, Pages 2021-2026

  De Zegher, Francis ^a,b   Francois, Inge ^a   Van Helvoirt, Monique ^a   Van Den Berghe, Greet ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE;

BODY HEIGHT; CHILD; CHILD GROWTH; FETUS; FETUS GROWTH; GIGANTISM; GROWTH HORMONE DEFICIENCY; GROWTH HORMONE RELEASE; GROWTH RETARDATION; HORMONE RESISTANCE; HUMAN; INFANT; PRIORITY JOURNAL; REVIEW; SHORT STATURE;

BODY HEIGHT; CHILD; GROWTH; GROWTH HORMONE; HUMANS; SOMATOMEDINS;

EID: 0030853989     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.82.7.2021     Document Type: Review

References (87)

1. Gluckman PD. 1989 Fetal growth: an endocrine perspective. Acta Paediatr Scand. 349(Suppl):21-24.
2. de Zegher F, Kaplan SL, Grumbach MM, et al. 1995 The foetal pituitary, postmaturity and breech presentation. Acta Paediatr. 83:1100-1102.
3. Tanner JM. 1994 Growth from birth to two: a critical review. Acta Med Auxol. 26:7-45.
4. Fitzhardinge PM, Steven EM. 1972 The small-for-date infant. II. Neurologic and intellectual sequelae. Pediatrics. 50:50-57.
5. Barker DJP, Osmond C, Golding J, Kuh D, Wadsworth MEJ. 1989 Growth in utero. Blood pressure in childhood and adult life, and mortality from cardiovascular disease. Br Med J. 298:564-567.
6. Phillips DIW, Barker DJP, Hales CN, Hirst S, Osmond C. 1994 Thinness at birth and insulin resistance in adult life. Diabetologia. 37:150-154.
7. Fitzhardinge PM, Steven EM. 1972 The small-for-date infant. I. Later growth patterns. Pediatrics. 49:671-681.
8. Karlberg J, Albertsson-Wikland K. 1995 Growth in full-term small-for-gestational-age infants: from birth to final height. Pediatr Res. 38:733-739.
9. Dunn PM. 1985 The search for perinatal definitions and standards. Acta Paediatr Scand. 319(Suppl):7-16.
10. Ingraham HA, Albert VR, Chen R, et al. 1990 A family of POU-domain and Pit-1 tissue-specific transcription factors in pituitary and neuroendocrine development. Annu Rev Physiol. 52:773-782.
11. Castrillo JL, Theill LE, Karin M. 1991 Function of the homeodomain protein GHF1 in pituitary cell proliferation. Science. 253:197-199.
12. Voss JW, Rosenfeld MG. 1992 Anterior pituitary development: short tales from dwarf mice. Cell. 70:527-529.
13. Kaplan SL, Grumbach MM, Shepard TH. 1972 The ontogenesis of human fetal hormones. I. Growth hormone and insulin. J Clin Invest. 51:3080-3093.
14. Frankenne F, Closset J, Gomez F, Scippo ML, Smal J, Hennen G. 1988 The physiology of growth hormones (GHs) in pregnant women and partial characterization of the placental GH variant. J Clin Endocrinol Metab. 66:1171-1180.
15. de Zegher F, Vanderschueren-Lodeweyckx M, Spitz B, et al. 1990 Perinatal growth hormone (GH) physiology: effect of GH-releasing factor on maternal and fetal secretion of pituitary and placental GH. J Clin Endocrinol Metab. 77:520-522.
16. Heinrichs C, de Zegher F, Vansnick F, Vokaer A, Christophe C, Frankenne F. 1994 Fetal hypopituitarism: perinatal endocrine and morphological studies in two cases. Acta Paediatr. 83:448-451.
17. Hindmarsch P. 1987 Hormonal levels in the human fetus between 14 and 22 weeks gestation. Early Hum Dev. 15:253-258.
18. de Zegher F, Kimpen J, Raus J, Vanderschueren-Lodeweyckx M. 1990 Hypersomatotropism in the dysmature infant at term and preterm birth. Biol Neonate. 58:188-191.
19. Bassett NS, Gluckman PD. 1986 Pulsatile growth hormone secretion in the ovine fetus and neonatal lamb. J Endocrinol. 109:307-312.
20. Gluckman PD, Parsons Y. 1985 Growth hormone secretion in the fetal sheep following stereotaxic electrolytic lesioning of the fetal hypothalamus. J Dev Physiol. 7:25-36.
21. Grumbach MM, Gluckman PD. 1994 The human fetal hypothalamus and pituitary gland: the maturation of neuroendocrine mechanisms controlling the secretion of fetal pituitary growth hormone, prolactin, gonadotropins, adrenocorticotropin-related peptides and thyrotropin. In: Tulchinsky D, Little AB, eds. Maternal and fetal endocrinology, 2nd ed. Philadelphia: Saunders; 193-261.
22. Gluckman PD, Mueller PL, Kaplan SL, Rudolph AM, Grumbach MM. 1979 Hormone ontogeny in the ovine fetus. I. Ovine growth hormone in mid and late gestation. Endocrinology. 104:162-168.
23. de Zegher F, Daaboul J, Grumbach MM, Kaplan SL. 1989 Hormone ontogeny in the ovine fetus and neonatal lamb. XXII. Effect of somatostatin on the growth hormone (GH) response to GH-releasing factor. Endocrinology. 124:1114-1117.
24. de Zegher F, Bettendorf M, Grumbach MM, Kaplan SL. 1990 Hormone ontogeny in the ovine fetus. XXV. Somatotrope desensitization to growth hormone (GH)-releasing factor independent of short-latency, ultrashortloop GH feedback. Neuroendocrinology. 52:429-433.
25. Lassare C, Hardouin S, Daffos F, Forestier F, Frankenne F, Binoux M. 1991 Serum insulin-like growth factors and insulin-like growth factor binding proteins in the human fetus: relationships with growth in normal subjects and in subjects with intrauterine growth retardation. Pediatr Res. 29:219-225.
26. Giudice LC, de Zegher F, Gargosky SE, et al. 1995 Insulin-like growth factors and their binding proteins in the term and preterm human fetus and neonate with normal and extremes of intrauterine growth. J Clin Endocrinol Metab. 80:1548-1555.
27. de Zegher F, Bettendorf M, Kaplan SL, Grumbach MM. 1988 Hormone ontogeny in the ovine fetus and neonatal lamb. XXI. Effect of exogenous insulin-like growth factor-1 on plasma growth hormone, insulin and glucose concentrations. Endocrinology. 123:658-660.
28. Hill DJ, Riley SC, Bassett NS, Waters MJ. 1992 Localization of the growth hormone receptor, identified by immunocytochemistry, in second trimester human fetal tissues and in placenta throughout gestation. J Clin Endocrinol Metab. 75:646-652.
29. Massa G, de Zegher F, Vanderschueren-Lodeweyckx M. 1992 Serum growth hormone-binding protein in the human fetus and infant. Pediatr Res. 32:69-72.
30. de Zegher F, Pernasetti F, Vanhole C, Devlieger H, Van den Berghe G, Martial JA. 1995 The prenatal role of thyroid hormone evidenced by fetomaternal pit-1 deficiency. J Clin Endocrinol Metab. 80:3127-3130.
31. Gluckman PD, Gunn AJ, Wray A, et al. 1992 Congenital idiopathic growth hormone deficiency is associated with prenatal and early postnatal growth failure. J Pediatr. 121:920-925.
32. Wit JM, van Unen H. 1992 Growth of infants with neonatal growth hormone deficiency. Arch Dis Child. 67:920-924.
33. Laron Z, Lilos P, Klinger B. 1993 Growth curves for Laron svndrome Arch Dis Child. 68:768-772.
34. DeLuca F, Bermasconi S, Blandino A, Cavallo L, Cistermino M. 1995 Auxological, clinical and neuroradiological findings in infants with early onset growth hormone deficiency. Acta Paediatr. 84:561-565.
35. Parkes MJ, Bassett JM. 1985 Antagonism by growth hormone of insulin action in fetal sheep. J Endocrinol. 105:379-382.
36. Stevens D, Alexander G. 1986 Lipid deposition after hypophysectomy and growth hormone treatment in the sheep fetus. J Dev Physiol. 8:139-145.
37. Werther GA, Haynes KM, Barnard R, Waters MJ. 1990 Visual demonstration of growth hormone receptors on human growth plate chondrocytes. J Clin Endocrinol Metab. 70:1725-1730.
38. Werther GA, Haynes K, Waters MJ. 1993 Growth hormone (GH) receptors are expressed on human mesenchymal tissue: identification of messenger ribonucleic acid and GH-binding protein. J Clin Endocrinol Metab. 76:1638-1644.
39. Gluckman PD, Cutfield W, Harding JE, et al. 1996 Metabolic consequences of intrauterine growth retardation. Acta Paediatr. 417(Suppl):3-6.
40. de Zegher F, Styne DM, Daaboul J, Bettendorf M, Kaplan SL, Grumbach MM. 1989 Hormone ontogeny in the ovine fetus and neonatal lamb. XX. Effect of age, breeding season and twinning on the growth hormone (GH) response to GH-releasing factor: evidence for a homeostatic role of fetal GH. Endocrinology. 124:124-128.
41. Bauer MK, Breier BH, Harding JE, Veldhuis JD, Gluckman PD. 1995 The fetal somatotropic axis during long-term maternal undernutrition in sheep: evidence for nutritional regulation in utero. Endocrinology. 136:1250-1257.
42. Gluckman PD. 1986 The role of pituitary hormones, growth factors and insulin in the regulation of fetal growth. In: Clarke JR, ed. Oxford reviews of reproductive biology, 8th ed. London: Oxford University Press; 2.
43. Woods KA, Camacho-Hubner C, Savage MO, Clark AJL. 1996 Intrauterine growth retardation and postnatal growth failure associated with deletion of the igf-1 gene. N Engl J Med. 335:1363-1367.
44. Deiber M, Chatelain P, Naville D, Putet G, Salle B. 1989 Functional hypersomatotropism in small for gestational age (SGA) newborn infants. J Clin Endocrinol Metab. 68:232-234.
45. Cornblath M, Parker ML, Reisner SH, Forbes AE, Daughaday WH. 1965 Secretion and metabolism of growth hormone in premature and full term infants. J Clin Endocrinol Metab. 25:209-218.
46. Adrian TE, Lucas A, Bloom SR, Aynsley-Green A. 1983 Growth hormone response to feeding in term and preterm neonates. Acta Paediatr Scand. 72:251-254.
47. Westphal O. 1968 Human growth hormone: a methodological and clinical study. Acta Paediatr Scand. 57(Suppl 182):1-81.
48. Miller JD, Esparza A, Wright NM, et al. 1993 Spontaneous growth hormone release in term infants: changes during the first four days of life. J Clin Endocrinol Metab. 76:1058-1062.
49. de Zegher F, Devlieger H, Veldhuis JD. 1993 Properties of growth hormone and prolactin hypersecretion by the human newborn on the clay of birth. J Clin Endocrinol Metab. 76:1177-1181.
50. de Zegher F, Van den Berghe G, Devlieger H, Eggermont E, Veldhuis JD. 1993 Dopamine inhibits neonatal growth hormone and prolactin hypersecretion. Pediatr Res. 34:642-645.
51. Ducharme JR, Grumbach MM. 1961 Studies on the effects of human growth hormone in premature infants. J Clin Invest. 40:243-247.
52. van Toledo-Eppinga L. 1995 Growth promoting interventions in preterm infants. PhD Thesis. Amsterdam: Free University Amsterdam.
53. Albertsson-Wikland K, Karlberg J. 1994 Natural growth in children born small for gestational age with and without catch-up growth. Acta Paediatr Scand. 399(Suppl):64-70.
54. Hokken-Koelega ACS, De Ridder MAJ, Lemmen RJ, et al. 1995 Children born small for gestational age: do they catch up? Pediatr Res. 38:267-271.
55. Fitzhardinge PM, Inwood S. 1989 Long-term growth in small-for-date children. Acta Paediatr Scand. 349(Suppl):27-33.
56. Ravelli GP, Stein ZA, Susser MW. 1976 Obesity in young men after famine exposure in utero and early infancy. N Engl J Med. 295:349-353.
57. Dietz WH. 1994 Critical periods in childhood for the development of obesity. Am J Clin Nutr. 59:955-959.
58. Colle E, Schiff D, Andrew G, Bauer CB, Fitzhardinge P. 1976 Insulin responses during catch-up growth of infants who were small for gestational age. Pediatrics. 57:63-71.
59. Leger J, Noel M, Limal JM, Czernichow P. 1996 Growth factors and intrauterine growth retardation: serum GH, IGF, and IGFBP-3 levels in children with intrauterine growth retardation as compared with normal control subjects: prospective study from birth to 2 years of age. Pediatr Res. 40:101-107.
60. Francois I, de Zegher F. 1997 Adrenarche and fetal growth. Pediatr Res. 41:440-442.
61. de Zegher F, Albertsson-Wikland K, Wilton P, et al. 1996 Growth hormone treatment of short children born small for gestational age: a metanalysis of four independent, randomized, controlled, multicentre studies. Acta Paediatr. 417(Suppl):27-31.
62. Tanner JM, Leijarraga H, Cameron N. 1975 The natural history of the Silver-Russell syndrome: a longitudinal study of thirty-nine cases. Pediatr Res. 9:611-623.
63. Davies PSW, Valley R, Preece MA. 1988 Adolescent growth and pubertal progression in the Silver-Russell syndrome. Arch Dis Child. 63:130-135.
64. Stanhope R, Preece MA, Hamill G. 1991 Does growth hormone treatment improve final height attainment of children with intrauterine growth retardation? Arch Dis Child. 66:1180-1183.
65. Chatelain P, Job JC, Blanchard J, et al. 1994 Dose-dependent catch-up growth after 2 years of growth hormone treatment in intrauterine growth-retarded children. J Clin Endocrinol Metab. 78:1454-1460.
66. Ranke MB, Lindberg A. 1496 Growth hormone treatment of short children born small for gestational age or with Silver-Russell syndrome: results from KIGS, including the first report on final height. Acta Paediatr Suppl. 417:18-26.
67. Ackland FM, Stanhope R, Eyre C, Hamill G, Jones J, Preece MA. 1988 Physiological growth hormone secretion in children with short stature and intra-uterine growth retardation. Horm Res. 30:241-245.
68. Rochiccioli P, Tauber M, Moisan V, Pienkowski C. 1989 Investigation of growth hormone secretion in patients with intrauterine growth retardation. Acta Paediatr Scand. 349(Suppl):42-46.
69. Albertsson-Wikland K. 1989 Growth hormone secretion and growth hormone treatment in children with intrauterine growth retardation. Acta Paediatr Scand. 349(Suppl):35-41.
70. de Waal WJ, Hokken-Koelega ACS, Stijnen T, de Muinck Keizer-Schrama SMPF, Drop SLS. 1994 Endogenous and stimulated GH secretion, urinary GH excretion and plasma IGF-I and IGF-II levels in prepubertal children with short stature after intrauterine growth retardation. Clin Endocrinol (Oxf). 41:621-630.
71. Boguszewski M, Rosberg S, Albertsson-Wikland K. 1995 Spontaneous 24-hour growth hormone profiles in prepubertal small for gestational age children. J Clin Endocrinol Metab. 80:2599-2606.
72. Van den Berghe G, de Zegher F, Lauwers P, Veldhuis JD. 1994 Growth hormone secretion in critical illness: effect of clopamine. J Clin Endocrinol Metab. 79:1141-1146.
73. Van den Berghe G, de Zegher F. 1996 Anterior pituitary function during critical illness and dopamine treatment. Crit Care Med. 24:1580-1590.
74. Job JC, Chatelain P, Rochiccioli P, Ponte C, Olivier M, Sagnard L. 1990 Growth hormone response to a bolus injection of 1-44 growth hormone-releasing hormone in very short children with intrauterine onset of growth failure. Florm Res. 33:161-165.
75. de Zegher F, Maes M, Gargosky SE, et al. 1996 High-dose growth hormone treatment of short children born small for gestational age. J Clin Endocrinol Metab. 81:1887-1892.
76. Boguszewski M, Jansson C, Rosberg S, Albertsson-Wikland K. 1996 Changes in serum IGF-1 and IGFBP-3 levels during growth hormone treatment in prepubertal short children born small for gestational age. J Clin Endocrinol Metab. 81:3902-3908.
77. Balsamo A, Tassoni P, Cassio A, et al. 1995 Response to growth hormone therapy in patients with growth hormone deficiency who at birth were small or appropriate in size for gestational age. J Pediatr. 126:474-477.
78. Chatelain PG, Cauderay MC, de Zegher F, et al. 1996 Growth hormone secretion and sensitivity in children born small for gestational age. Acta Paediatr. 417(Suppl):15-16.
79. Tanner JM, Whitehouse RH, Hughes PCR, Vince FP. 1971 Effect of human growth hormone for one to seven years on growth of 100 children, with growth hormone deficiency, low birth weight, inherited smallness, Turner's syndrome and other complaints. Arch Dis Child. 46:745-782.
80. Grunt JA, Enriquez AR, Daughaday WH, Budd S. 1972 Acute and long-term responses to hGH in children with idiopathic small-for-dates dwarfism. J Clin Endocrinol Metab. 35:157-168.
81. Foley Jr TP, Thompson RG, Shaw M, Baghdassavian A, Nissley SP, Blizzard RM. 1974 Growth responses to human growth hormone in patients with intra-uterine growth retardation. J Pediatr. 84:635-641.
82. Lanes R, Plotnick LP, Lee PA. 1979 Sustained effect of human growth hormone therapy on children with intra-uterine growth retardation. Pediatrics. 63:731-735.
83. Job JC, Chaussain JL, Job B, et al. 1996 Follow-up of three years of treatment with growth hormone and of one post-treatment year in children with severe growth retardation of intrauterine onset. Pediatr Res. 39:354-359.
84. Van Erum R, Mulier M, Carels C, Verbeke G, de Zegher F. Craniofacial growth in short children born small for gestational age: effect of growth hormone treatment. J Dent Res. In press.
85. Job JC, Rolland A. 1986 Histoire naturelle des retards de croissance debut intra-uterin. Arch Fr Pediatr. 43:301-306.
86. Westwood M, Kramer MS, Nunz D, Lovett JM, Watters GV. 1983 Growth and development of full term nonasphyxiated small-for-gestational age newborns: follow-up through adolescence. Pediatrics. 71:376-382.
87. deZegher F, Devlieger H, Veldhuis JD. 1992 Pulsatile and sexually dimorphic secretion of luteinizing hormone in the human infant on the day of birth. Pediatr Res. 32:605-607.