A Leu-Lys-rich antimicrobial peptide: Activity and mechanism

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1645, Issue 2, 2003, Pages 172-182

  Park, Yoonkyung ^a   Lee, Dong Gun ^a   Jang, Seung Hwan ^a   Woo, Eun Rhan ^a   Jeong, Hye Gwang ^a   Choi, Cheol Hee ^a   Hahm, Kyung Soo ^a  

^a Chosun University   (South Korea)

Author keywords

CA MA analogue P5 (P5); Cecropin A (1 8) magainin 2 (1 12) hybrid peptide (CA MA); Lys and Leu substitution

Indexed keywords

1,6 DIPHENYL 1,3,5 HEXATRIENE; CHOLESTEROL; LEUCINE; LIPOSOME; LYSINE; LYSYLLYSYLLYSYLLYSYLTRYPTOPHYLLYSYLLEUCYLPHENYLALANYLLYSYLLYSYLISOLEUCYLGLY CYLISOLEUCYLGLYCYLLYSYLPHENYLALANYLLEUCINAMIDE; LYSYLTRYPTOPHYLLYSYLLEUCYLPHENYLALANYLLYSYLLYSYLISOLEUCYLGLYCYLISOLEUCYLGLY CYLLYSYLPHENYLALANYLLEUCINAMIDE; LYSYLTRYPTOPHYLLYSYLLEUCYLPHENYLALANYLLYSYLLYSYLISOLEUCYLGLYCYLISOLEUCYLGLY CYLLYSYLPHENYLALANYLLEUCYLHISTIDYLSERYLALANYLLYSYLLYSYLPHENYLALANINAMIDE; LYSYLTRYPTOPHYLLYSYLLEUCYLPHENYLALANYLLYSYLLYSYLISOLEUCYLGLYCYLISOLEUCYLGLY CYLLYSYLPHENYLALANYLLEUCYLLYSYLLYSYLLYSINAMIDE; LYSYLTRYPTOPHYLLYSYLLYSYLLEUCYLLEUCYLLYSYLLYSYLPROLYLLEUCYLLEUCYLLYSYLLYSYL LEUCYLLEUCYLLYSYLLYSYLLEUCINAMIDE; LYSYLTRYPTOPHYLLYSYLLYSYLLYSYLLYSYLLYSYLLYSYLPROLYLLYSYLPHENYLALANYLLEUCINA MIDE; PEPTIDE; PHOSPHATIDYLCHOLINE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; ANTINEOPLASTIC AGENT; CECROPIN A(1 8)MAGAININ 2(1 12); CECROPIN A(1-8)MAGAININ 2(1-12); FLUORESCEIN ISOTHIOCYANATE; SODIUM AZIDE;

AMINO ACID SUBSTITUTION; ANTIBACTERIAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL MEMBRANE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; FLOW CYTOMETRY; HEMOLYSIS; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; SCANNING ELECTRON MICROSCOPY; AMINO ACID SEQUENCE; CANDIDA ALBICANS; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; COMPARATIVE STUDY; DRUG DESIGN; DRUG EFFECT; MICROBIOLOGICAL EXAMINATION; MOLECULAR GENETICS; SYNTHESIS;

BACTERIA (MICROORGANISMS);

AMINO ACID SEQUENCE; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; ANTINEOPLASTIC AGENTS; CANDIDA ALBICANS; CELL SURVIVAL; DIPHENYLHEXATRIENE; DRUG DESIGN; FLOW CYTOMETRY; FLUORESCEIN-5-ISOTHIOCYANATE; LEUCINE; LYSINE; MICROBIAL SENSITIVITY TESTS; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; SODIUM AZIDE; TUMOR CELLS, CULTURED;

EID: 0038690584     PISSN: 15709639     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1570-9639(02)00541-1     Document Type: Article

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