Aspects of the immunopharmacology of thymosin α1

Clinical and Applied Immunology Reviews

Volumn 1, Issue 3-4, 2001, Pages 187-191

  Hadden, John W ^a,b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b NONE   (United States)

Author keywords

Immunopharmacology; IRX 2; IRX 3; Thymosin

Indexed keywords

ALPHA INTERFERON; ANTINEOPLASTIC AGENT; CYTOKINE; GAMMA INTERFERON; IRX 2; IRX 3; RECOMBINANT INTERLEUKIN 1; RECOMBINANT INTERLEUKIN 2; THYMOSIN ALPHA1; UNCLASSIFIED DRUG;

CANCER; CELL PROLIFERATION; CLINICAL TRIAL; DISEASE MODEL; DRUG EFFICACY; HUMAN; IMMUNE DEFICIENCY; IMMUNOPHARMACOLOGY; IN VIVO STUDY; INFECTION; LYMPHOCYTOPENIA; MONOTHERAPY; NONHUMAN; PRIORITY JOURNAL; REVIEW; SPLEEN CELL; T LYMPHOCYTE; THYMOCYTE; THYMUS;

EID: 0038662069     PISSN: 15291049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1529-1049(01)00012-5     Document Type: Review

References (15)

1. J.A. Coto E.M. Hadden M. Sauro N. Zorn J.W. Hadden Interleukin 1 regulates secretion of zinc-thymulin by thymic epithelial cells and its action on T lymphocyte proliferation and nuclear protein kinase C Proc Natl Acad Sci USA 89 1992 7752-7756
2. A. Goldstein E. Garaci Combination therapies 1993 Plenum Press New York
3. 1 chemistry, mechanisms of action and clinical applications A. Goldstein E. Garaci Combination Therapies 1993 Plenum Press New York 39-48
4. A. Gramenzi C. Cursaro P. Andrione M. Bernardi Thymalfason clinical pharmacology and antiviral applications BioDrugs 9 1998 477-486
5. J.W. Hadden J. Endicott P. Baekey P. Skipper E.M. Hadden Interleukins and contrasuppression induce immune regression of head and neck cancer Arch Otolaryngol Head Neck Surg 120 1994 395-403
6. J.W. Hadden Treatment of zinc deficiency is an immunotherapy Int J Immunopharmacol 17 1995 697-701
7. 1 potently augments T lymphocyte responses of hydrocortisone-treated aged mice Int J Immunopharmacol 17 1995 821-828
8. J.W. Hadden Thymic hormones and interleukins in T cell development and reconstitution Int J Immunorehab 5 1997 3-8
9. Hadden J.W. Method for treating immunodeficiency. U.S. Patent #5632983 (U.S. Patent Office) 1997.
10. J.W. Hadden Thymic involution Ann NY Acad Sci 830 1998 352-359
11. L. Matera Endocrine, paracrine, and autocrine actions of prolactin on immune cells Life Sci 59 1996 599-614
12. 1 on interleukin 2 production and receptor expression in normal human lymphocytes Int J Immunopharmacol 11 1989 789-800
13. S. Shu P. Naylor J.-L. Touraine J.W. Hadden IL-1, ICAM, LFA-3, and hydrocortison differentially regulate cytokine secretions by human fetal thymic epithelial cells Thymus 24 1996 89-99
14. J.E. Talmadge E.S. Reed A. Kessinger C.A. Koszynski G.A. Perry C.I. Gordy C. Millak M.L. Thomas S.J. Pirruccello B.A. Lotheby M.A. Arnson J.D. Jackson Immunologic attributes of cytokine mobilized peripheral blood stem cells and recovery following transplantation Bone Marrow Transp 17 1996 101-109
15. E. Verastegui E.M. Hadden J. Barrera A. Meneses J.W. Hadden A natural cytokine mixture (IRX-2) and interference with immune suppression induce immune regression and improved survival in head and neck cancer Int J Immunorehab 12 Suppl 1999 5-11