Targeting of mitogen-activated protein kinases and phosphatidylinositol 3 kinase inhibits hepatocyte growth factor/scatter factor - Induced angiogenesis

Circulation

Volumn 107, Issue 23, 2003, Pages 2955-2961

  Sengupta, Shiladitya ^a,b   Sellers, Lynda A ^a   Li, Rung Chi ^a   Gherardi, Ermanno ^a   Zhao, Ganlin ^b   Watson, Nicki ^c   Sasisekharan, Ram ^d   Fan, Tai Ping D ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^d Massachusetts Inst of Technology ^*

Author keywords

Angiogenesis; Endothelium; Growth substances; Signal transduction

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; GROWTH PROMOTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; SCATTER FACTOR; WORTMANNIN; XENON 133;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; DRUG EFFECT; ENDOTHELIUM; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMALS; BIOLOGICAL ASSAY; CELL DIVISION; CELLS, CULTURED; CHROMONES; COLLAGEN; DRUG COMBINATIONS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; FLAVONOIDS; HEPATOCYTE GROWTH FACTOR; HUMANS; LAMININ; MALE; MICE; MICE, INBRED BALB C; MITOGEN-ACTIVATED PROTEIN KINASES; MORPHOLINES; NEOVASCULARIZATION, PHYSIOLOGIC; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEOGLYCANS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 0038649977     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000077501.19266.E5     Document Type: Article

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