The development of a new bioartificial liver and its application in 12 acute liver failure patients

World Journal of Gastroenterology

Volumn 9, Issue 4, 2003, Pages 829-832

  Ding, Yi Tao ^a   Qiu, Yu Dong ^a   Chen, Zhong ^a   Xu, Qing Xiang ^a   Zhang, He Yuan ^a   Tang, Qing ^a   Yu, De Cai ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; AMMONIA; BILIRUBIN; POLYSULFONE;

ADOLESCENT; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; AMMONIA BLOOD LEVEL; ANIMAL CELL; ARTICLE; ARTIFICIAL LIVER; BILIRUBIN BLOOD LEVEL; BIOARTIFICIAL ORGAN; BIOCHEMISTRY; BIOCOMPATIBILITY; BIOMEDICAL TECHNOLOGY ASSESSMENT; BIOREACTOR; CLINICAL ARTICLE; CLINICAL TRIAL; FEMALE; HEMOFILTRATION; HUMAN; LIVER CELL; LIVER FAILURE; LIVER FUNCTION; MALE; MORTALITY; NONHUMAN; PLASMAPHERESIS; PROTHROMBIN TIME; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; SWINE;

EID: 0038638955     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v9.i4.829     Document Type: Article

References (16)

1. Emond JC, Whitington PF, Thistlethwaite JR, Cherqui D, Alonso EA, Woodle IS, Vogelbach P, Busse-Henry SM, Zucker AR, Broelsch CE. Transplantation of two patients with one liver. Ann Surg 1990; 212: 14-22
2. Shaw BW. More questions than answers. Liver Transplant Surg 1995; 1: 404-407
3. Everhart JE, Lombardero M, Detre KM, Zetterman RK, Wiesner RH, Lake JR, Hoffnagle JH. Increased waiting time for liver transplantation results in higher mortality. Transplantation 1997; 64: 1300-1306
4. Bilsuttil W, Klintmalm B. Transplantation of the Liver. Philadelphia. W. B. Saunders Company 1996; 861
5. Emond JC, Whitington PF, Thistlethwaite JR, Alonso EM, Broelsch CE. Reduced-size orthotopic liver transplantation: Use in the management of children with chronic liver disease. Hepatology 1989; 10: 867-872
6. Friedman AL. Why bioartificial liver support remains the holy grail. ASAIO 1998; 44: 241-243
7. Kamihira M, Yamada K, Hamamoto R, Iijima S. Speroid formation of hepatocytes using synthetic polymer. Ann NY Acad Sci 1997; 831: 398-407
8. Sussman NL, Gislason GT, Conlin CA, Kelly JH. The hepatic extracorporeal liver assist device: Initial clinical experience. Artif Organs 1994; 18: 390-396
9. Dixit V. Development of a bioartificial liver using isolated hepatocytes. Artif Organs 1994; 18: 371-384
10. Hui T, Rozga J, Demetriou AA. Bioartificial liver support. J Hepatobiliary Surg 2001; 8: 1-15
11. Suh KS, Lilja H, Kamohara Y, Eguchi S, Arkadopoulos N, Neuman T, Demetriou AA, Rozga J. Bioartificial liver treatment in rats with fulminant hepatic failure: Effect on DNA-binding activity of liver-enriched and growth-associated transcription factors. J Surg Res 1999; 85: 243-250
12. Seglen PO. Preparation of isolated rat liver cells. Methods Cell Biol 1976; 13: 23-28
13. Rozga J, Williams F, Ro MS, Neuzil DF, Giorgio TD, Backfisch G, Moscioni AD, Hakim R, Demetriou AA. Development of a bioartificial liver: Properties and function of a hollow fiber module inoculated with liver cells. Hepatology 1993; 17: 258-265
14. Cuervas-Mons V, Colas A, Rivera JA, Prados E. In vivo efficacy of a bioartificial liver in improving spontaneous recovery from fulminant hepatic failure: A controlled study in pigs. Transplantation 2000; 69: 337-344
15. Flendrig LM, La-Soe JW, Jorning GGA, Steenbeek A, Karlsen OT, Bovee WMM, Ladiges NC, Te Velde AA, Chamuleau RA. In vitro evaluation of a novel bioreactor based on an integral oxygenator and spirally wound nonwoven polyester matrix for hepatocyte culture as small aggregates. J Hepatol 1997; 26: 1379-1392
16. Chen Z, Ding Y, Zhang H. Cryopreservation of suckling pig hepatocytes. Ann Clin Lab Sci 2001; 31: 391-398