Identification of the residues in the helix F/G loop important to catalytic function of membrane-bound prostacyclin synthase

Biochemistry

Volumn 42, Issue 19, 2003, Pages 5609-5617

  Deng, Hui ^a   Wu, Jiaxin ^a   So, Shui Ping ^a   Ruan, Ke He ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HOMOLOGY MODELING;

ANTIBODIES; CONFORMATIONS; ENZYMES; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SUBSTRATES;

BIOCHEMISTRY;

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; PROSTACYCLIN SYNTHASE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SUBSTRATE; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN INTERACTION;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CATALYTIC DOMAIN; COS CELLS; CYTOCHROME P-450 ENZYME SYSTEM; DNA; ENDOPLASMIC RETICULUM; HUMANS; INTRACELLULAR MEMBRANES; INTRAMOLECULAR OXIDOREDUCTASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SOLUTIONS; SUBSTRATE SPECIFICITY;

EID: 0038629254     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi026749z     Document Type: Article

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