Tissue-engineered versus native cartilage: Linkage between cellular mechano-transduction and biomechanical properties

Novartis Foundation Symposium

Volumn 249, Issue , 2003, Pages 52-69

  Lee, Jennifer H ^a   Kisiday, John ^a   Grodzinsky, Alan J ^a,b,c   Goldstein, ^d   Caplan, ^d   Kafienah, ^d  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b USA   (United States)

^c Massachusetts Institute of Technology Cambridge   (United States)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOMATERIAL; BONE MORPHOGENETIC PROTEIN; COLLAGEN; GLYCOSAMINOGLYCAN;

ANIMAL; ARTICULAR CARTILAGE; BIOLOGICAL MODEL; BIOMECHANICS; BIOSYNTHESIS; CARTILAGE CELL; CATTLE; CELL CULTURE; COMPARATIVE STUDY; CULTURE MEDIUM; CYTOLOGY; DRUG EFFECT; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; HUMAN; HYDROGEL; HYDROPHOBICITY; INSTRUMENTATION; MECHANICAL STRESS; METABOLISM; PHYSIOLOGY; PROTEIN SECONDARY STRUCTURE; REVIEW; TISSUE ENGINEERING; WEIGHT BEARING;

ANIMALS; BIOCOMPATIBLE MATERIALS; BIOMECHANICS; BONE MORPHOGENETIC PROTEINS; CARTILAGE, ARTICULAR; CATTLE; CELLS, CULTURED; CHONDROCYTES; COLLAGEN; CULTURE MEDIA; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; GLYCOSAMINOGLYCANS; HUMANS; HYDROGELS; HYDROPHOBICITY; MODELS, BIOLOGICAL; PROTEIN STRUCTURE, SECONDARY; STRESS, MECHANICAL; TISSUE ENGINEERING; WEIGHT-BEARING;

EID: 0038619072     PISSN: None     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (33)

1. Bonassar LJ, Grodzinsky AJ, Frank EH, Davila SG, Bhaktav NR, Trippel SB 2001 The effect of dynamic compression on the response of articular cartilage to insulin-like growth factor-I. J Orthop Res 19:11-17
2. Buschmann MD, Gluzband YA, Grodzinsky AJ, Hunziker EB 1995 Mechanical compression modulates matrix biosynthesis in chondrocyte/agarose culture. J Cell Sci 108:1497-1508
3. Butler DL, Goldstein SA, Guilak F 2000 Functional tissue engineering: the role of biomechanics. J Biomech Eng 122:570-575
4. Chen AC, Bae WC, Schinagl RM, Sah RL 2001 Depth- and strain-dependent mechanical and electromechanical properties of full-thickness bovine articular cartilage in confined compression. J Biomech 34:1-12
5. Davisson T, Kunig S, Chen A, Sah R, Ratcliffe A 2002 Static and dynamic compression modulate matrix metabolism in tissue engineered cartilage. J Orthop Res 20:842-848
6. De Witt MT, Handley CJ, Oakes BW, Lowther DA 1984 In vitro response of chondrocytes to mechanical loading. The effect of short term mechanical tension. Connect Tissue Res 12:97-109
7. DiMicco MA, Waters SN, Akeson WH, Sah RL 2002 Integrative articular cartilage repair: dependence on developmental stage and collagen metabolism. Osteoarthritis Cartilage 10:218-225
8. Fujisawa T, Hattori T, Takahashi K, Kuboki T, Yamashita A, Takigawa M 1999 Cyclic mechanical stress induces extracellular matrix degradation in cultured chondrocytes via gene expression of matrix metalloproteinases and interleukin-1. J Biochem (Tokyo) 125:966-975
9. Grimshaw MJ, Mason RM 2000 Bovine articular chondrocyte function in vitro depends upon oxygen tension. Osteoarthritis Cartilage 8:386-392
10. Herberhold C, Faber S, Stammberger T et al 1999 In situ measurement of articular cartilage deformation in intact femoropatellar joints under static loading. J Biomech 32:1287-1295
11. Hodge WA, Fijan RS, Carlson KL, Burgess RG, Harris WH, Mann RW 1986 Contact pressures in the human hip joint measured in vivo. Proc Natl Acad Sci USA 83:2879-2883
12. Hunter CJ, Imler SM, Malaviya P, Nerem RM, Levenston ME 2002 Mechanical compression alters gene expression and extracellular matrix synthesis by chondrocytes cultured in collagen I gels. Biomaterials 23:1249-1259
13. Jin M, Frank EH, Quinn TM, Hunziker EB, Grodzinsky AJ 2001 Tissue shear deformation stimulates proteoglycan and protein biosynthesis in bovine cartilage explants. Arch Biochem Biophys 395:41-48
14. Kaarniranta K, Elo M, Sironen R et al 1998 Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation. Proc Natl Acad Sci USA 95:2319-2324
15. Kaarniranta K, Holmberg CI, Lammi MJ, Eriksson JE, Sistonen L, Helminen HJ 2001 Primary chondrocytes resist hydrostatic pressure-induced stress while primary synovial cells and fibroblasts show modified Hsp70 response. Osteoarthritis Cartilage 9:7-13
16. Kaps C, Bramlage C, Smolian H et al 2002 Bone morphogenetic proteins promote cartilage differentiation and protect engineered artificial cartilage from fibroblast invasion and destruction. Arthritis Rheum 46:149-162
17. Kisiday J, Jin M, Kurz B et al 2002 Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair. Proc Natl Acad Sci USA 99:9996-10001
18. Lee RB, Wilkins RJ, Razaq S, Urban JP 2002a The effect of mechanical stress on cartilage energy metabolism. Biorheology 39:133-143
19. Lee JW, Qi WN, Scully SP 2002b The involvement of betal integrin in the modulation by collagen of chondrocyte-response to transforming growth factor-beta1. J Orthop Res 20:66-75
20. Li KW, Falcovitz YH, Nagrampa JP et al 2000 Mechanical compression modulates proliferation of transplanted chondrocytes. J Orthop Res 18:374-382
21. Maroudas A 1979 Physicochemical properties of articular cartilage. In: Freeman MAR (ed) Adult articular cartilage, 2nd edn, Tunbridge Wells, England, p 215-290
22. Mauck RL, Soltz MA, Wang CC et al 2000 Functional tissue engineering of articular cartilage through dynamic loading of chondrocyte-seeded agarose gels. J Biomech Eng 122:252-260
23. Mizuno S, Allemann F, Glowacki J 2001 Effects of medium perfusion on matrix production by bovine chondrocytes in three-dimensional collagen sponges. J Biomed Mater Res 56:368-375
24. Ragan PM, Badger AM, Cook M et al 1999 Down-regulation of chondrocyte aggrecan and type-II collagen gene expression correlates with increases in static compression magnitude and duration. J Orthop Res 17:836-842
25. Sah RL, Kim YJ, Doong JY, Grodzinsky AJ, Plaas AH, Sandy JD 1989 Biosynthetic response of cartilage explants to dynamic compression. J Orthop Res 7:619-636
26. Sironen RK, Karjalainen HM, Torronen K et al 2002 High pressure effects on cellular expression profile and mRNA stability. A cDNA array analysis. Biorheology 39:111-117
27. Smith RL, Rusk SF, Ellison BE et al 1996 In vitro stimulation of articular chondrocyte mRNA and extracellular matrix synthesis by hydrostatic pressure. J Orthop Res 14:53-60
28. Takahashi K, Kubo T, Kobayashi K et al 1997 Hydrostatic pressure influences mRNA expression of transforming growth factor-beta 1 and heat shock protein 70 in chondrocyte-like cell line. J Orthop Res 15:150-158
29. Takahashi I, Nuckolls GH, Takahashi K et al 1998 Compressive force promotes sox9, type II collagen and aggrecan and inhibits IL-1beta expression resulting in chondrogenesis in mouse embryonic limb bud mesenchymal cells. J Cell Sci 111:2067-2076
30. 2+/calmodulin-dependent factors mediate transduction of compression-induced signals in bovine articular chondrocytes. Biochem J 361:689-696
31. Valhmu WB, Stazzone EJ, Bachrach NM et al 1998 Load-controlled compression of articular cartilage induces a transient stimulation of aggrecan gene expression. Arch Biochem Biophys 353:29-36
32. Vincent T, Hermansson M, Bolton M, Wait R, Saklatvala J 2002 Basic FGF mediates an immediate response of articular cartilage to mechanical injury. Proc Natl Acad Sci USA 99:8259-8564
33. Wang CC, Guo XE, Sun D, Mow VC, Ateshian GA, Hung CT 2002 The functional environment of chondrocytes within cartilage subjected to compressive loading: a theoretical and experimental approach. Biorheology 39:11-25