Lytic switch protein (ORF50) response element in the Kaposi's sarcoma-associated herpesvirus K8 promoter is located within but does not require a palindromic structure

Virology

Volumn 310, Issue 1, 2003, Pages 72-84

  Seaman, William T ^a   Quinlivan, E Byrd ^a,b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

DNA binding protein; Gene expression regulation; K8 promoter; Kaposi's sarcoma associated herpesvirus; Lytic switch protein; ORF50; Palindrome; Response element; Viral transcription activator; Virus replication

Indexed keywords

LYTIC SWITCH PROTEIN; PALINDROMIC DNA; PHORBOL 13 ACETATE 12 MYRISTATE; UNCLASSIFIED DRUG; VIRUS PROTEIN; IMMEDIATE EARLY PROTEIN; RTA PROTEIN, HUMAN HERPESVIRUS 8; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; DNA RESPONSIVE ELEMENT; GENE IDENTIFICATION; GENE LOCATION; GENE STRUCTURE; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; LYMPHOID CELL; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE HOMOLOGY; TRANSCRIPTION INITIATION SITE; VIRUS TRANSCRIPTION; ANIMAL; CELL LINE; CHEMISTRY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

HERPESVIRIDAE;

ANIMALS; BASE SEQUENCE; CELL LINE; HERPESVIRUS 8, HUMAN; HUMANS; IMMEDIATE-EARLY PROTEINS; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RESPONSE ELEMENTS; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSFECTION; VIRAL PROTEINS;

EID: 0038544285     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0042-6822(03)00095-3     Document Type: Article

References (54)

1. Adamson A.L., Darr D., Holley-Guthrie E., Johnson R.A., Mauser A., Swenson J., Kenney S. Epstein-Barr virus immediate-early prteoins BZLF1 and BRLF1 activate the ATF2 transcription factor by increasing the levels of phosphorylated p38 and c-Jun N-terminal kinases. J. Virol. 74:2000;1224-1233.
2. Adamson A.L., Kenney S. Rescue of the Epstein-Barr virus BZLF1 mutant, Z(S186A), early gene activation defect by the BRLF1 gene product. Virology. 251:1998;187-197.
3. Arias J., Alberts A.S., Brindle P., Claret F.X., Smeal T., Karin M., Feramisco J., Montiminy M. Activation of cAMP and mitogen responsive genese relies on a common nuclear factor. Nature. 370:1994;226-229.
4. Bannister A.J., Kouzarides T. The CBP co-activator is a histone acetyltransferase. Nature. 384:1996;641-643.
5. Carey M., Kolmann J., Katz D.A., Gradovill L., Barbeis L., Miller G. Transcriptional synergy by the Epstein-Barr virus transactivator ZEBRA. J. Virol. 66:1992;4805-4813.
6. Cesarman E., Chang Y., Moore P.S., Said J.W., Knowles D.M. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas. New Engl. J. Med. 332:1995;1186-1191.
7. Chang Y., Cesarman E., Pessin M.S., Lee F., Culpepper J., Knowles D.M., Moore P.S. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science. 266:1994;1865-1869.
8. Chrivia J.C., Kwok R.P., Lamb N., Hagiwara M., Montminy M., Goodman R.h. Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature. 365:1993;855-859.
9. Duan W., Wang S., Liu S., Wood C. Characterization of Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8 ORF57 promoter. Arch. Virol. 146:2001;403-413.
10. Flemington E., Speck S.H. Autoregulation of Epstein-Barr virus putative lytic switch gene BZLF1. J. Virol. 64:1990;1227-1232.
11. Flemington E.K. Herpesvirus lytic replication and the cell cycle arresting new developments. J. Virol. 75:2001;4475-4481.
12. Gessain, A., Sudaka, A., Briere, J., Fouchard, N., Nicola, M.A., Rio, B., Arborio, M., Troussard, X., Audouin, J., Diebold, J., de The, G., 1996. Kaposi's sarcoma-associated herpes-like virus (human herpesvirus 8) DNA sequences in multicentric Castlemans's disease: is there any relevant association in non-human immunodeficiency virus-infected patients? Blood 87, 414-416.
13. Gradoville L., Gerlach J., Grogan E., Shedd D., Nikiforow S., Metroka C., Miller G. Kaposi's sarcoma-associated herpesvirus open reading frame 50/Rta protein activates the entire viral lytic cycle in the HH-B2 primary effusion lymphoma cell line. J. Virol. 74:2000;6207-6212.
14. Gruffat H., Duran N., Buisson M., Wild F., Buckland R., Sergeant A. Characterization of an R-binding site mediating the R-induced activation of the Epstein-Barr virus BMLF1 promotor. J. Virol. 661:1992;46-52.
15. Gwack Y., Byun H., Hwang S., Lim C., Choe J. CREB-binding protein and histone deacetylase regulate the transcriptional activity of Kaposi's sarcoma-associated herpesvirus open reading frame 50. J. Virol. 75:2001;1909-1917.
16. Hall K.T., Whitehouse A. The activation domain of herpesvirus samiri R protein interacts with the TATA-binding protein. J. Virol. 73:1999;9756-9763.
17. Hardwick J.M., Lieberman P.M., Hayward S.D. A new Epstein-Barr virus transactivator, R, induces expression of a cytoplasmic early antigen. J. Virol. 62:1988;2274-2284.
18. Ho S.N., Hunt H.D., Horton R.M., Pullen J.K., Pease L.R. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene. 77:1989;51-59.
19. Holley-Guthrie E.A., Quinlivan E.B., Kenney S. The Epstein-Barr virus (EBV) BMRF1 promoter for early antigen (EA-D) is regulated by the EBV transactivators, BRLF1 and BZLF1, in a cell-specific manner. J. Virol. 64:1990;3753-3759.
20. Horton R.M., Hunt H.D., Ho S.N., Pullen J.K., Pease L.R. Engineering hybrid genes without the use of restriction enzymes gene splicing by overlap extension. Gene. 77:1989;61-68.
21. Jenkins P.J., Binne U.K., Farrell P.J. Histone acetylation and reactivation of Epstein-Barr virus from latency. J. Virol. 74:2000;710-720.
22. Kamei Y., Xu L., Heinzel T., Torchia J., Kurokawa R., Gloss B., Lin S.C., Heyman R.A., Rose D.W., Glass C.K., Rosenfeld M.G. A CBP integrator complex mediates transcriptional activation and AP-1 inhibiiton by nuclar receptors. Cell. 85:1996;403-414.
23. Kenney S., Holley-Guthrie E., Mar E.C., Smith M. The Epstein-Barr virus BMLF1 promoter contains an enhancer element that is responsive to the BZLF1 and BRLF1 transactivators. J. Virol. 63:1989;3878-3883.
24. Klinge C.M. Estrogen receptor interaction with estrogen response elements. Nucleic Acids Res. 29:2001;2905-2919.
25. Liang Y., Chang J., Lynch S.J., Lukac D.M., Ganem D. The lytic switch protein of KSHV activates gene expression via functional interaction with RBP-Jkappa (CSL), the target of the Notch signaling pathway. Genes Dev. 16:2002;1977-1989.
26. Lin S.F., Robinson D.R., Miller G., Kung H.J. Kaposi's sarcoma-associated herpesvirus encodes a bZIP protein with homology to BZLF1 of Epstein-Barr virus. J. Virol. 73:1999;1909-1917.
27. Liu S., Liu P., Borras A., Chatila T., Speck S.H. Cyclosporin-A sensitive induction of the Epstein-Barr virus lytic switch is mediated via a novel pathway involving a MEF2 family member. EMBO J. 16:1997;143-153.
28. Lukac D.M., Garibyan L., Kirshner J.R., Palmeri D., Ganem D. DNA binding by Kaposi's sarcoma-associated herpesvirus lytic switch protein is necessary for transcriptional activation of two viral delayed early promoters. J. Virol. 75:2001;6786-6799.
29. Lukac D.M., Kirshner J.R., Ganem D. Transcriptional activation by the product of open reading frame 50 of Kaposi's sarcoma-associated herpesvirus is required for lytic viral reactivation in B cells. J. Virol. 73:1999;9348-9361.
30. Lukac D.M., Renne R., Kirshner J.R., Ganem D. Reactivation of Kaposi's sarcoma-associated herpesvirus infection from latency by expression of the ORF 50 transactivator, a homolog of the EBV R protein. Virology. 252:1998;304-312.
31. Manet E., Allera C., Gruffat H., Mikaelian I., Rigolet A., Sergeant A. The acidic activation domain of the Epstein-Barr virus transcription factor R interacts in vitro with both TBP and TFIIB and is cell-specifically potentiated by a proline-rich region. Gene Exp. 3:1993;49-59.
32. Martin K.J., Lillie J.W., Green M.R. Evidence for interaction of different eukaryotic transcriptional activators with distinct cellular targets. Nature. 346:1990;147-152.
33. Miller G. The switch betwen EBV latency and replication. Yale J. Biol. Med. 62:1989;205-213.
34. Miller G., Heston L., Grogan E., Gradoville L., Rigsby M., Sun R., Shedd D., Kushnaryov V.M., Grossberg S., Chang Y. Selective switch between latency and lytic replication of Kaposi's sarcoma herpesvirus and Epstein Barr virus in dually infected body cavity lymphoma cells. J. Virol. 71:1997;314-324.
35. Nelson, C.C., Hendy, S.C., Shukin, R.J., Cheng, H., Bruchovsky, N., Koop, B.F., 1999. Determinants of DNA sequence specificity of the androgen, progesterone and glucocorticoid receptors: evidence for differential steroid receptor response elements. Mol. Endocrinol. 13, 2090-2107.
36. Ogryzko V.V., Schiltz R.L., Russanova V., Howard B.H., Nakatani Y. The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell. 87:1996;953-959.
37. Petz I.N., Nardulli A.M. Sp1 binding sites and an estrogen response element half-site are involved in regulation of the human progesterone receptor A promoter. Mol. Endocrinol. 14:2000;972-985.
38. Quinlivan E.B., Holley-Guthrie E., Mar E.C., Smith M.S., Kenney S. The Epstein-Barr virus BRLF1 immediate-early gene product transactivates the human immunodeficiency virus type 1 long terminal repeat by a mechanism which is enhancer independent. J. Virol. 64:1990;1817-1820.
39. Quinlivan E.B., Holley-Guthrie E.A., Morris M., Gutsch D., Bachenheimer S., Kenney S.C. Direct BRLF1 binding is required for cooperative BZLF1/BRLF1 activation of the Epstein-Barr virus early promoter, BMRF1. Nucleic Acids Res. 21:1993;1999-2007. [published erratum appears in Nucleic Acids Res. 21(8), 1999-2007 (1993)].
40. Ragoczy T., Miller G. Role of the Epstein-Barr virus Rta protein in activation of distinct classes of viral lytic cycle genes. J. Virol. 73:1999;9858-9866.
41. Renne R., Zhong W., Herndier B., McGrath M., Abbey N., Kedes D., Ganem D. Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture. Nat. Med. 2:1996;342-346.
42. Rooney C.M., Rowe D.T., Ragot T., Farrell P.J. The spliced BZLF1 gene of Epstein-Barr virus (EBV) transactivates an early EBV promoter and induces the virus productive cycle. J. Virol. 63:1989;3109-3116.
43. Russo J.J., Bohensky R.A., Chien M.-C., Chen J., Yan M., Maddelena D., Parry J.P., Peruzzi D., Edelman I.S., Chang Y., Moore P.S. Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8). Proc. Nat. Acad. Sci. USA. 93:1996;14862-14867.
44. Sakakibara S., Ueda K., Chen J., Okuno T., Yamanishi K. Octamer-binding sequence is a key element for the autoregulation of Kaposi's sarcoma-associated herpesvirus ORF50/Lyta gene expression. J. Virol. 75:2001;6894-6900.
45. Seaman W.T., Ye D., Wang R.X., Hale E.E., Weisse M., Quinlivan E.B. Gene expression from the ORF50/K8 region of Kaposi's sarcoma-associated herpesvirus. Virology. 263:1999;436-449.
46. Segouffin C., Gruffat H., Sergeant A. Repression by RAZ of Epstein-Barr virus bZIP transcription factor EB1 is dimerization independent. J. Gen. Virol. 77:1996;1529-1536.
47. Sinclair A.J., Brimmell M., Shanahan F., Farrell P.J. Pathways of activation of the Epstein-Barr virus productive cycle. J. Virol. 65:1991;2237-2244.
48. Song M.J., Brown H.J., Wu T.T., Sun R. Transcription activation of polyadenylated nuclear RNA by Rta in human herpesvirus 8/Kaposi's sarcoma-associated herpesvirus. J. Virol. 75:2001;3129-3140.
49. Soulier J., Grollet L., Oksenhendler E., Cacoub P., Cazals-Hatem D., Babinet P., d'Agay M.F., Clauvel J.P., Raphael M., Degos L., et al. Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease. Blood. 86:1995;1276-1280.
50. Wang S., Liu S., Wu M., Geng Y., Wood C. Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8 ORF50 gene product contains a potent C-terminal activation domain which activates gene expression via a specific target sequence. Arch. Virol. 146:2001;1415-1426.
51. Wang S., Liu S., Wu M.H., Geng Y., Wood C. Identification of a cellular protein that interacts and synergizes with the RTA (ORF50) protein of Kaposi's sarcoma-associated herpesvirus in transcriptional activation. J. Virol. 75:2001;11961-11997.
52. Zalani S., Holley-Guthrie E., Kenney S. Epstein-Barr viral latency is disrupted by the immediate-early BRLF1 protein through a cell-specific mechanism. Proc. Nat. Acad. Sci. USA. 93:1996;9194-9199.
53. Zhang L., Chiu J.L., Lin J.C. Activation of human herpesvirus 8 (HHV-8) thymidine kinase (TK) tataa-less promoter by HHV-8 ORF50 gene product is SP1 dependent. DNA Cell Biol. 17:1998;735-742.
54. Zhong W., Wang H., Herndier B., Ganem D. Restricted expression of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) genes in Kaposi's sarcoma. Proc. Nat. Acad. Sci. USA. 93:1996;6641-6646.