Activin B in patients with granulosa cell tumors: Serum levels in comparison to inhibin

Acta Obstetricia et Gynecologica Scandinavica

Volumn 82, Issue 6, 2003, Pages 570-574

  Vihko, Kimmo K ^a   Bläuer, Merja ^b   Puistola, Ulla ^c   Tuohimaa, Pentti ^b  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^c OULU UNIVERSITY HOSPITAL   (Finland)

Author keywords

Activin; Granulosa cell tumors; Inhibin; Tumor marker

Indexed keywords

INHIBIN; MYELOPID;

ADOLESCENT; ADULT; ARTICLE; BLOOD SAMPLING; CASE REPORT; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE MARKER; FEMALE; FOLLOW UP; GRANULOSA CELL TUMOR; HORMONE BLOOD LEVEL; HUMAN; HUMAN TISSUE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; TUMOR GROWTH;

ACTIVINS; ADOLESCENT; BIOLOGICAL ASSAY; DISEASE PROGRESSION; FEMALE; GRANULOSA CELL TUMOR; HUMANS; INHIBINS; MIDDLE AGED; NEOPLASM, RESIDUAL; OVARIAN NEOPLASMS;

EID: 0038541935     PISSN: 00016349     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0412.2003.00146.x     Document Type: Article

References (17)

1. Hoskins WJ, Rubin C. Malignant gonadal stromal tumors of ovary: clinical features and Management. In: Coppleson M (ed) Gynologic Oncology. Fundamental Principals and Clinical Practice, Vol. 2. Churchill Livingstone, Edinburgh, 1992: 961-970.
2. Gerhenson D. Management of early ovarian cancer: germ cell and sex-cord stromal tumors. Gynecol Oncol 1994; 55: 262-72.
3. Hines J, Mahmoud A, Moore JL, Fine KP, Lage JM, Barnes WA. Recurrent granulosa-cell tumor of the ovary 37 years after initial diagnosis: a case report and review of the literature. Gynecol Oncol 1996; 60: 484-8.
4. Lappöhn RE, Burger H, Bouma J, Bangah M, Krans M, de Bruijn HW. Inhibin as a marker for granulosa cell tumors. New Engl J Med 1989; 321: 790-3.
5. Vihko KK, Bläuer M, Kujansuu E, Vilska S, Albäck T, Tuimala R et al. Activin B. detection by an immunoradiometric assay in human serum during ovarian stimulation and late pregnancy. Hum Reprod 1998; 13: 841-6.
6. Burger HG. Clinical utility of inhibin measurements. J Clin Endocrinol Metab 1993; 76: 1391-5.
7. Healy DL, Mamers P, Bangah M, Burger HG. Clinical and pathophysiological aspects of inhibin. Hum Reprod; xx (Suppl. 8): 138-40.
8. Slujimer AV, Heineman MJ, Evers JH, de Jong FH. Peripheral vein, ovarian vein and ovarian tissue levels of inhibin in a postmenopausal patient with a granulosa cell tumor. Acta Endocrinol 1993; 129: 311-4.
9. Jobling T, Burger HG, Mamers P, MacLachlan V, Burger HG, Quinn M et al. A prospective study of inhibin in granulosa cell tumors of the ovary. Gynecol Oncol, 1994; 55: 285-9.
10. Cooke I, O'Brien M, Charnock FM, Groome N, Ganesan TS. Inhibin as a marker for ovarian cancer. Br J Cancer 1995; 71: 1046-50.
11. Fuller PJ, Chu S, Jobling T, Mamers P, Healy DL, Burger HG. Inhibin subunit gene expression in ovarian canver. Gynecol Oncol 1999; 73: 273-9.
12. Robertson DM, Cahir N, Burger HG, Mamers P, Groome N. Inhibin forms in serum from postmenopausal women with ovarian cancer. Clin Endocrinol 1999; 50: 381-6.
13. Kingsley DM. The TGF-β superfamily: new members, new receptors, and new genetic tests of function in different organ systems. Genes Dev 1994; 8: 133-46.
14. Vihko KK, Piquette G, Hsueh AJW. Intraovarian signalling mechanisms and control. In: Grave GD, Gordon BC Jr (eds) Sexual Precocity: Etiology Diagnosis and Treatment. Raven Press, 1993: 253-61.
15. Bläuer M, Wichmann L, Punnonen R, Tuohimaa P. Measurement of activin B in human saliva and localization of activin subunits in rat salivary glands. Biochem Biophys Res Commun 1996; 222: 230-5.
16. Yamashita K, Yamato M, Shikone T, Minami S, Imai M, Nishimori K et al. Production of inhibin A and inhibin B in human ovarian sex cord tumors. Am J Obstet Gynecol 1997; 177: 1450-7.
17. Petraglia F, Luisi S, Pautier P, Sabourin JC, Rey R, Lhomme C et al. Inhibin B is the major form of inhibin/activin family secreted by granulosa cell tumors. J Clin Endocrinol Metab 1998; 83: 1029-32.