Inhibin B is the major form of inhibin/activin family secreted by granulosa cell tumors

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 3, 1998, Pages 1029-1032

  Petraglia, Felice ^a   Luisi, Stefano ^a   Pautier, Patricia ^b   Sabourin, Jean Christophe ^b   Rey, Rodolfo ^c   Lhomme, Catherine ^b   Bidart, Jean Michel ^b  

^a UNIVERSITY OF UDINE   (Italy)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c ECOLE NORMALE SUPÉRIEURE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; INHIBIN; INHIBIN A;

ARTICLE; CANCER REGRESSION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; EPITHELIUM TUMOR; FEMALE; GRANULOSA CELL TUMOR; HUMAN; HUMAN TISSUE; OVARY CANCER; PRIORITY JOURNAL; PROTEIN SECRETION;

FALLOPIA;

EID: 0031733509     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.83.3.4800     Document Type: Article

References (22)

1. Young RH, Scully RE. 1992 Endocrine tumors of the ovary. Current Topics in Pathology, N Sasano, ed. Springer-Verlag, Berlin, pp 114-164
2. Amsterdam A, Selvaraj N. 1997 Control of differenciation, transformation, and apopotosis in granulosa cells by oncogenes, oncoviruses, and tumor suppressor genes. Endocrine Rev. 18 :435-461.
3. Burger HG, Fuller PJ. 1996 The inhibin/activin family in ovarian cancer. Trends Endocrinol. Metab. 7 :197-202.
4. Kumar TR, Wang Y, Matzuk MM 1996 Gonadotropins are essential modifier factors for gonadal rumor development in inhibin-deficient mice, Endocrinology 137:4210-4216.
5. Ying SY. 1988 Inhibins, activins, and follistatins : gonadal proteins modulating the secretion of follicle-stimulating hormone. Endocr. Rev. 9 :267-293.
6. Lappöhn RE, Burger HG, Bouma J, Bangah M, Krans M, deBruijn WA. 1989 Inhibin as a marker for granulosa-cell tumors. N Engl J Med. 321:790-793.
7. McConnell DS, Padmanabhan V, Pollak TB, Groome N, Ireland JJ, Midgley AR Jr. 1996 Develoment of a two-site solid-phase immunochemiluminescent assay for measurement of dimeric inhibin-A in human serum and other biological fluids. Clin. Chem. 42 :1159-1167.
8. Rey R, Lhommé C, Marcillac I, et al. 1996 Antimüllerian hormone as a serum marker of granulosa cell tumors of the ovary: comparative study with serum α-inhibin and estradiol. Am. J. Obstet. Gynecol. 174:958-965.
9. Silverman LA, Gitelman SE. 1996 Immunoreactive inhibin, müllerian inhibitory substance, and activin as biochemical markers for juvenile granulosa cell tumors. J. Pediatrics 129 :918-921.
10. Petraglia F, Luisi S, Benedetto C, et al. 1997 Changes of dimeric inhibin B levels throughout healthy gestation and in women with gestational diseases. J. Clin. Endocrinol. Metab. 82 :2991-2995.
11. Di Simone N, Crowley WF, Wang Q-F, Sluss PM, Schneyer AL. 1996 Characterization of inhibin/activin subunit, follistatin and activin type II receptors in human ovarian cancer cell lines: a potential role in autocrine growth regulation. Endocrinology 137 :486-494.
12. Gurunsinghe CJ, Healy DL, Joblings T, Mamers P, Burger HG. 1995 Inhibin and activin are demonstrable by immunohistochemistry in ovarian tumor tissue. Gynecol. Oncol. 57 :27-32.
13. Arora DS, Cooke IE, Ganesan TS, et al. 1997 Immunohistochemical expression of inhibin/activin subunits in epithelial and granulosa cell tumours of the ovary. J. Pathol. 181:413-418.
14. th Annual Meeting of the Endocrine Society, Minneapolis, June 11-14, 1997. absrr. P1-501.
15. Harada K, Shintani Y, Sakamoto Y, Wakatsuki M, Shitsukawa K, Saito S. 1996 Serum immunoreactive activin A levels in normal subjects and patients with various diseases. J. Clin. Endocrinol. Metab. 81 :2125-2130.
16. Cooke I, O'Brien MO, Charnock FM, Groome N, Gamesan TS. 1995 Inhibin as a marker for ovarian cancer. Br. J. Cancer 71 :1046-1050.
17. Burger HG, Robertson DM, Cahir N, et al. 1996 Characterization of inhibin immunoreactivity in post-menopausal women with ovarian tumors. Clin. Endocrinol. 44:413-418.
18. Lambert-Messerlian G, Steinhoff M, Zheng W, et al. 1997 Multiple immunoreactive inhibin proteins in serum from postmenopausal women with epithelial ovarian cancer. Gynecol. Oncol. 65 :512-516.
19. Groome NP, Illingwoth PJ, O'Brien M, et al. 1996 Measurement of dimeric inhibin B throughout the human menstrual cycle. J . Clin. Endocrinol. Metab ; 81 :1401-1405.
20. Kotlar TJ, Young RH, Albanese C, Crowley WF, Scully RE, Jameson JL. 1997 A mutation in the follicle-stimulating hormone receptor occurs frequently in human ovarian sex cord tumors. J. Clin. Endocrinol. Metab. 82 :1020-1026.
21. Sicinski P, Donaher JL, Geng Y, et al. 1996 Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis. Nature, 384 :470-474.
22. Matzuk MM, Finegold MJ, Mishina Y, Bradley A, Behringer RR. 1995 Synergistic effects of inhibins and mullerian-inhibiting substance on testicular tumorigenesis. Mol. Endocrinol. 9 :1337-1345.