Selective activation of thrombin is a critical determinant for vertebrate lens regeneration

Current Biology

Volumn 13, Issue 10, 2003, Pages 877-881

  Imokawa, Yutaka ^a,b   Brockes, Jeremy P ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b RIKEN   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMBYSTOMA; AMBYSTOMA MEXICANUM; ANIMALIA; SALAMANDRIDAE; VERTEBRATA;

EID: 0038523738     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(03)00294-X     Document Type: Article

References (22)

1. Brockes, J.P., Kumar, A., and Velloso, C.P. (2001). Regeneration as an evolutionary variable. J. Anat. 199, 3-11.
2. Eguchi, G., and Shingai, R. (1971 ). Cellular analysis on localization of lens forming potency in the newt iris epithelium. Dev. Growth Differ. 13, 337-349.
3. Eguchi, G. (1998). Transdifferentiation as the basis of eye lens regeneration. In Cellular and Molecular Basis of Regeneration, P. Ferretti and J. Geraudie, eds. (Chichester: John Wiley & Sons), pp. 207-228.
4. Okada, T.S. (1991). Transdifferentiation: Flexibility in Cell Differentiation (New York: Oxford University Press).
5. Del Rio-Tsonis, K., and Tsonis, P.A. (2003). Eye regeneration at the molecular age. Dev. Dyn. 226, 211-224.
6. Stone, L.S. (1967). An investigation recording all salamanders which can and cannot regenerate a lens from the dorsal iris. J. Exp. Zool. 164, 87-103.
7. Reyer, R.W, (1954). Regeneration of the lens in the amphibian eye. Quart. Rev. Biol. 29, 1-46.
8. Eguchi, G., Abe, S.I., and Watanabe, K. (1974). Differentiation of lens-like structures from newt iris epithelial cells in vitro. Proc. Natl. Acad. Sci. USA 71, 5052-5056.
9. Eguchi, G., and Okada, T.S. (1973). Differentiation of lens tissue from the progeny of chick retinal pigment cells cultured in vitro: a demonstration of a switch of cell types in clonal cell culture. Proc. Natl. Acad. Sci. USA 70, 1495-1499.
10. Yasuda, K., Okada, T.S., Eguchi, G., and Hayashi, M. (1978). A demonstration of a switch of cell type in human fetal eye tissues in vitro: pigmented cells of the iris or the retina can transdifferentiate into lens. Exp. Eye Res. 26, 591-595.
11. Tanaka, E.M., Gann, A.A., Gates, P.B., and Brockes, J.P. (1997). Newt myotubes reenter the cell cycle by phosphorylation of the retinoblastoma protein. J. Cell Biol. 136, 155-165.
12. Tanaka, E.M., Drechsel, D.N., and Brockes, J.P. (1999). Thrombin regulates S-phase re-entry by cultured newt myotubes. Curr. Biol. 9, 792-799.
13. Brockes, J.P., and Kumar, A. (2002). Plasticity and reprogramming of differentiated cells in amphibian regeneration. Nat. Rev. Mol. Cell Biol. 3, 566-574.
14. Velloso, C.P., Simon, A., and Brockes, J.P. (2001). Mammalian postmitotic nuclei reenter the cell cycle after serum stimulation in newt/mouse hybrid myotubes. Curr. Biol. 11, 855-858.
15. Simon, A., and Brockes, J.P. (2002). Thrombin activation of S-phase reentry by cultured pigmented epithelial cells of adult newt iris. Exp. Cell Res. 281, 101-106.
16. Kumar, A., Velloso, C.P., Imokawa, Y., and Brockes, J.P. (2000). Plasticity of retrovirus-labelled myotubes in the newt limb regeneration blastema. Dev. Biol. 218, 125-136.
17. Bode, W., Mayr, I., Baumann, U., Huber, R., Stone, S.R., and Hofsteenge, J. (1989). The refined 1.9 Å crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment. EMBO J. 8, 3467-3475.
18. Hutton, R.A., Laffan, M.A., and Tuddenham, E.G.D. (1999). Normal haemostasis. In Postgraduate Haematology, Fourth Edition, A.V. Hoffbrand, S.M. Lewis, and E.G.D. Tuddenham, eds. (Oxford: Butterworth-Heinemann), pp. 550-580.
19. Tsiang, M., Jain, A.K., and Gibbs, C.S. (1997). Functional requirements for inhibition of thrombin by antithrombin III in the presence and absence of heparin. J. Biol. Chem. 272, 12024-12029.
20. Bron, A.J., Tripathi, R.C., and Tripathi, B.J. (1997). Wolff's Anatomy of the Eye and Orbit, Eighth Edition (London: Chapman & Hall Medical).
21. Ramalho-Santos, M., Yoon, S., Matsuzaki, Y., Mulligan, R.C., and Melton, D.A. (2002). 'Sternness': transcriptional profiling of embryonic and adult stem cells. Science 298, 597-600.
22. Day, F.A., and Neufeld, D.A. (1997). Use of enzyme overlay membranes to survey proteinase activity in frozen sections: cathepsin-like and plasmin-like activity in regenerating newt limbs. J. Histochem. Cytochem. 45, 779-783.