Tremor/ataxia syndrome in fragile X carrier males

Movement Disorders

Volumn 17, Issue 4, 2002, Pages 744-745

  Leehey, Maureen A ^a,e   Hagerman, Randi J ^b   Landau, William M ^c   Grigsby, Jim ^a   Tassone, Flora ^d   Hagerman, Paul J ^d  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FRAGILE X MENTAL RETARDATION PROTEIN;

ADULT; ARTICLE; ATAXIA; BRAIN ATROPHY; CEREBELLAR ATAXIA; CLINICAL ARTICLE; FRAGILE X SYNDROME; GENE MUTATION; HUMAN; MALE; MENTAL DEFICIENCY; OLIVOPONTOCEREBELLAR ATROPHY; PARKINSONISM; PRIORITY JOURNAL; TREMOR; VIDEOTAPE;

EID: 0038521838     PISSN: 08853185     EISSN: None     Source Type: Journal    
DOI: 10.1002/mds.10208     Document Type: Article

References (8)

1. Hagerman RJ, Leehey M, Heinrichs W, et al. Intention tremor, Parkinsonism, and generalized brain atrophy in older male carriers of fragile X. Neurology 2001;57:127-130.
2. Rousseau F, Rouillard P, Morel ML, Khandjian EW, Morgan K. Prevalence of carriers of premutation-size alleles of the FMR1 gene and implications for the population genetics of the fragile X syndrome. Am J Hum Genet 1995;57:1006-1018.
3. Franke P, Leboyer M, Gansicke M, et al. Genotype-phenotype relationship in female carriers of the premutation and full mutation of FMR-1. Psychiatry Res 1998;80:113-127.
4. Tassone F, Hagerman RJ, Taylor AK, et al. Clinical involvement and protein expression in individuals with the FMR1 premutation. Am J Med Genet 2000;91:144-152.
5. Hagerman RJ, Staley LW, O'Connor R, et al. Learning-disabled males with a fragile X CGG expansion in the upper premutation size range. Pediatrics 1996;97:122-126.
6. Allingham-Hawkins DJ, Babul-Hirji R, Chitayat D, et al. Fragile X premutation is a significant risk factor for premature ovarian failure: the international collaborative POF in fragile X study - preliminary data. Am J Med Genet 1999;83:322-325.
7. Hagerman RJ. Fragile X syndrome. In: Neurodevelopmental disorders: diagnosis and treatment. New York: Oxford University Press; 1999. p 61-132.
8. Tassone F, Hagerman RJ, Taylor AK, Gane LW, Godfrey TE, Hagerman PJ. Elevated levels of FMR1 mRNA in carrier males: a new mechanism of involvement in fragile X syndrome. Am J Hum Genet 2000;66:6-15.