Fragile X premutation is a significant risk factor for premature ovarian failure: The international collaborative POF in fragile X study - Preliminary data

American Journal of Medical Genetics

Volumn 83, Issue 4, 1999, Pages 322-325

  Allingham Hawkins, Diane J ^a   Babul Hirji, Riyana ^b   Chitayat, David ^b   Holden, Jeanette J A ^b   Yang, Kathy T ^b   Lee, C ^b   Hudson, R ^b   Gorwill, H ^b   Nolin, Sarah L ^b   Glicksman, Anne ^b   Jenkins, Edmund C ^b   Brown, W Ted ^b   Howard Peebles, Patricia N ^b   Becchi, Cindy ^b   Cummings, Emilie ^b   Fallon, Lee ^b   Seitz, Suzanne ^b   Black, Susan H ^b   Vianna Morgante, Angela M ^b   Costa, Silvia S ^b   Otto, Paulo A ^b   Mingroni Netto, Regina C ^b   Murray, Anna ^b   Webb, J ^b   MacSwinney, F ^b   Dennis, N ^b   Jacobs, Patricia A ^b   Syrrou, Maria ^b   Georgiou, Ioannis ^b   Patsalis, Phillipos C ^b   Giovannucci Uzielli, Maria L ^b   Guarducci, S ^b   Lapi, E ^b   Cecconi, A ^b   Ricci, U ^b   Ricotti, G ^b   Biondi, C ^b   Scarselli, B ^b   Vieri, F ^b   more..

^a NORTH YORK GENERAL HOSPITAL   (Canada)

^b NONE

Author keywords

Fragile X premutation; Fragile X syndrome; Premature menopause; Premature ovarian failure

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; EARLY MENOPAUSE; FEMALE; FRAGILE X SYNDROME; GENETIC RISK; GENETIC VARIABILITY; HETEROZYGOTE DETECTION; HIGH RISK POPULATION; HUMAN; MAJOR CLINICAL STUDY; ONSET AGE; OVARY INSUFFICIENCY; PRIORITY JOURNAL; SCREENING TEST;

FALLOPIA;

EID: 0033515496     PISSN: 01487299     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19990402)83:4<322::AID-AJMG17>3.0.CO;2-B     Document Type: Article

References (6)

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2. Cronister A, Schreiner R, Wittenberger M, Amiri K, Harris K, Hagerman RJ. 1991. Heterozygous fragile X females: historical, physical, cognitive, and cytogenetic features. Am J Med Genet 38:269-274.
3. Feng Y, Lakkis L, Devys D, Warren ST. 1995. Quantitative comparison of FMR1 gene expression in normal and premutation alleles. Am J Hum Genet 56:106-113.
4. Partington MW, Moore DY, Turner GM. 1996. Confirmation of early menopause in fragile X carriers. Am J Med Genet 64:370-372.
5. Schwartz CE, Dean J, Howard-Peebles PN, Bugge M, Mikkelsen M, Tommerup N, Hull C, Hagerman R, Holden JJA, Stevenson RE. 1994. Obstetrical and gynecological complications in fragile X carriers: a multicenter study. Am J Med Genet 51:400-402.
6. Vianna-Morgante AM, Costa SS, Pares AS. Verreschi ITN. 1996. FRAXA premutation associated with premature ovarian failure. Am J Med Genet 64:373-375.