Structural basis for catalysis and substrate specificity of Agrobacterium radiobacter N-carbamoyl-D-amino acid amidohydrolase

Journal of Biological Chemistry

Volumn 278, Issue 28, 2003, Pages 26194-26201

  Chen, Cheng Yu ^a   Chiu, Wei Chun ^a   Liu, Jai Shin ^a   Hsu, Wen Hwei ^b   Wang, Wen Ching ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CONFORMATIONS; CRYSTAL STRUCTURE; ENZYMES; MUTAGENESIS; SPECTRUM ANALYSIS; SUBSTRATES;

MUTANTS;

CATALYSIS;

AMIDASE; ARGININE; ASPARAGINE; CARBOXYL GROUP; CYSTEINE; GLUTAMIC ACID; LYSINE; N CARBAMOYL DEXTRO AMINO ACID AMIDOHYDROLASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ENZYME BINDING; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; GENE CONSTRUCT; HYDROLYSIS; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHIZOBIUM RADIOBACTER; STRUCTURE ANALYSIS;

AMIDOHYDROLASES; BINDING SITES; CATALYSIS; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; ELECTRONS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; KINETICS; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RHIZOBIUM; SUBSTRATE SPECIFICITY;

AGROBACTERIUM; AGROBACTERIUM TUMEFACIENS; BACTERIA (MICROORGANISMS); NEGIBACTERIA;

EID: 0038506716     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M302384200     Document Type: Article

References (30)

1. Syldatk, C., Läufer, A., Müller, R., and Höke, H. (1990) Adv. Biochem. Eng. Biotechnol. 41, 30-75
2. Olivieri, R., Fascetti, E., Angelini, L., and Degen, L. (1981) Biotechnol. Bioeng. 23, 2173-2183
3. Runser, S., Chinski, N., and Ohleyer, E. (1990) Appl. Microbiol. Biotechnol. 33, 382-388
4. Nanba, H., Ikenaka, Y., Yamada, Y., Yajima, K., Takano, M., and Takahashi, S. (1998) Biosci. Biotechnol. Biochem. 62, 875-881
5. Moller, A., Syldatk, C., Schulze, M., and Wagner, F. (1988) Enzyme Microb. Technol. 10, 618-625
6. Ogawa, J., Shimizu, S., and Yamada, H. (1993)Eur. J. Biochem. 212, 685-691
7. Ogawa, J., Chung, M. C.-M., Hida, S., Yamada, H., and Shimizu, S. (1994) J. Biotechnol. 38, 11-19
8. Ikenaka, Y., Nanba, H., Yamada, Y., Yajima, K., Takano, M., and Takahashi, S. (1998) Biosci. Biotechnol. Biochem. 62, 882-886
9. Takahashi, S., Ohashi, T., Kii, Y., Kumagai, H., and Yamada, H. (1979) J. Ferment. Technol. 57, 328-332
10. Nakai, T., Hasegawa, T., Yamashita, E., Yamamoto, M., Kumasaka, T., Ueki, T., Nanba, H., Ikinaka, Y., Takahashi, S., Sato, M., and Tsukihara, T. (2000) Structure 8, 729-739
11. Wang, W. C., Hsu, W. H., Chien, F. T., and Chen, C. Y. (2001) J. Mol. Biol. 306, 251-261
12. Grifantini, R., Pratesi, C., Galli, G., and Grandi, G. (1996) J. Biol. Chem. 271, 9326-9331
13. Pace, H. C., Hodawadekar, S. C., Draganescu, A., Huang, J., Bieganowski, P., Pekarsky, Y., Croce, C. M., and Brenner, C. (2000) Curr. Biol. 10, 907-917
14. Pace, H. C., and Brenner, C. (2001) Genome Biology http://genomebiology.com/2001/2/1/reviews/0001
15. Hsu, W. H., Chien, F. T., Hsu, C. L., Wang, T. C., Yuan, H. S., and Wang, W. C. (1999) Acta Crystallogr. Sect. D Biol. Crystallogr. 55, 694-695
16. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
17. Gordon, S. A., Fleck, A., and Bell, J. (1978) Ann. Clin. Biochem. 15, 270-275
18. Leslie, A. G. (1999) Acta Crystallogr. Sect. D Biol. Crystallogr. 55, 1696-1702
19. Collaborative (1994) Acta Crystallogr. Sect. D Biol. Crystallogr. 50, 760-763
20. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
21. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. Sect. A 47, 110-119
22. Murshudov, G. N., Vagin, A. A., and Dodson, E. J. (1997) Acta Crystallogr. Sect. D Biol. Crystallogr. 53, 240-255
23. Perrakis, A., Morris, R., and Lamzin, V. S. (1999) Nat. Struct. Biol. 6, 458-463
24. Winn, M. D., Isupov, M. N., and Murshudov, G. N. (2001) Acta Crystallogr. Sect. D Biol. Crystallogr. 57, 122-133
25. Laskowski, R. A., MacArthur, M. W., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291
26. Read, R. J. (1986) Acta Crystallogr. Sect. A 42, 140-149
27. Kleywegt, G. J., and Jones, T. A. (1997) Methods Enzymol. 277, 525-545
28. Kraulis, P. J. (1991) J. Appl. Crystallogr. 24, 946-950
29. Merrit, E. A., and Murphy, M. E. P. (1994) Acta Crystallogr. Sect. D Biol. Crystallogr. 50, 869-873
30. Romao, M. J., Turk, D., Gomis-Rüth, F.-X., and Huber, R. (1992) J. Mol. Biol. 226, 1111-1130