메뉴 건너뛰기




Volumn 35, Issue 2, 2003, Pages 133-139

The antioxidant status during maturation of reticulocytes to erythrocytes in type 2 diabetics

Author keywords

Antioxidants; Diabetes mellitus; Erythrocytes; Free radicals; Maturation; Oxidative stress; Reticulocytes

Indexed keywords

ANTIOXIDANT; CATALASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE;

EID: 0038499446     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(03)00071-6     Document Type: Article
Times cited : (76)

References (61)
  • 1
    • 0036667555 scopus 로고    scopus 로고
    • Superoxide dismutase multigene family: A comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression
    • Zelko I.N., Mariani T.J., Folz R.J. Superoxide dismutase multigene family a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression . Free Radic. Biol. Med. 33:2002;337-349.
    • (2002) Free Radic. Biol. Med. , vol.33 , pp. 337-349
    • Zelko, I.N.1    Mariani, T.J.2    Folz, R.J.3
  • 2
    • 0001822282 scopus 로고    scopus 로고
    • Oxygen is a toxic gas: An introduction to oxygen toxicity and reactive oxygen species
    • B. Halliwell, & J.M.C. Gutteridge. New York: Oxford University Press
    • Halliwell B., Gutteridge J.M.C. Oxygen is a toxic gas an introduction to oxygen toxicity and reactive oxygen species . Halliwell B., Gutteridge J.M.C. Free radicals in biology and medicine. 1999;7-17 Oxford University Press, New York.
    • (1999) Free radicals in biology and medicine , pp. 7-17
    • Halliwell, B.1    Gutteridge, J.M.C.2
  • 3
    • 0032756392 scopus 로고    scopus 로고
    • The susceptibility of red blood cells to autoxidation in type 2 diabetic patients with angiopathy
    • Konukoglu D., Akcay T., Dincer Y., Hatemi H. The susceptibility of red blood cells to autoxidation in type 2 diabetic patients with angiopathy. Metabolism. 48:1999;1481-1484.
    • (1999) Metabolism , vol.48 , pp. 1481-1484
    • Konukoglu, D.1    Akcay, T.2    Dincer, Y.3    Hatemi, H.4
  • 4
    • 0012311303 scopus 로고    scopus 로고
    • Biochemistry of redox signalling in the activation of oxidative stress genes
    • D.L. Gilbert, & C.A. Colton. New York: Kluwer Academic/Plenum Publishers
    • Gonzalez-Flecha B., Demple B. Biochemistry of redox signalling in the activation of oxidative stress genes. Gilbert D.L., Colton C.A. Reactive oxygen species in biological systems. 1999;133-154 Kluwer Academic/Plenum Publishers, New York.
    • (1999) Reactive oxygen species in biological systems , pp. 133-154
    • Gonzalez-Flecha, B.1    Demple, B.2
  • 5
    • 0013579140 scopus 로고
    • Shortened red cell life span in diabetes. Mechanism of hemolysis
    • G. Fiorelli. New York: Raven
    • Percasmona G.R., Bosia A., Ghigo D. Shortened red cell life span in diabetes. Mechanism of hemolysis. Fiorelli G. Advances in red cell biology. 1982;391-397 Raven, New York.
    • (1982) Advances in red cell biology , pp. 391-397
    • Percasmona, G.R.1    Bosia, A.2    Ghigo, D.3
  • 6
    • 0038050207 scopus 로고
    • Reversibile hematologic sequelae of diabetes mellitus A
    • Lahrman M.C. Reversibile hematologic sequelae of diabetes mellitus A. Intern. Med. 8:1977;425-429.
    • (1977) Intern. Med. , vol.8 , pp. 425-429
    • Lahrman, M.C.1
  • 7
    • 0024408737 scopus 로고
    • Erythrocyte membrane lipid peroxidation and glycosylated hemoglobin in diabetes
    • Jain S.K., McVie R., Duett J., Herbst J.J. Erythrocyte membrane lipid peroxidation and glycosylated hemoglobin in diabetes. Diabetes. 38:1989;1539-1543.
    • (1989) Diabetes , vol.38 , pp. 1539-1543
    • Jain, S.K.1    McVie, R.2    Duett, J.3    Herbst, J.J.4
  • 8
    • 0035992597 scopus 로고    scopus 로고
    • Susceptibility of glutathione and glutathione-related antioxidant activity to hydrogen peroxide in patients with type 2 diabetes: Effect of glycemic control
    • Yildiz D., Zeynep A., Hasan I., Tulay A. Susceptibility of glutathione and glutathione-related antioxidant activity to hydrogen peroxide in patients with type 2 diabetes effect of glycemic control . Clin. Biochem. 35:2002;297-301.
    • (2002) Clin. Biochem. , vol.35 , pp. 297-301
    • Yildiz, D.1    Zeynep, A.2    Hasan, I.3    Tulay, A.4
  • 11
    • 0019126972 scopus 로고
    • Biochemical changes during reticulocyte maturation in culture. A comparison of genetically different sheep erythrocytes
    • Tucker E.M., Young J.D. Biochemical changes during reticulocyte maturation in culture. A comparison of genetically different sheep erythrocytes. Biochem. J. 192:1980;33-39.
    • (1980) Biochem. J. , vol.192 , pp. 33-39
    • Tucker, E.M.1    Young, J.D.2
  • 12
    • 85031146396 scopus 로고    scopus 로고
    • Lamberg, S. L.; Rothstein, R., eds. Hematology and urinalysis: functional medical laboratory manual. Westport, CT: Avi Pub Co; 1980
    • Lamberg, S. L.; Rothstein, R., eds. Hematology and urinalysis: functional medical laboratory manual. Westport, CT: Avi Pub Co; 1980.
  • 13
    • 85031152827 scopus 로고    scopus 로고
    • Todd, S. Clinical diagnosis by laboratory methods. In: Davidson, I.; Wells, B. B., eds. The blood. Philadelphia: W. B. Saunders Co.; 1963:83
    • Todd, S. Clinical diagnosis by laboratory methods. In: Davidson, I.; Wells, B. B., eds. The blood. Philadelphia: W. B. Saunders Co.; 1963:83.
  • 14
    • 0017872475 scopus 로고    scopus 로고
    • Buege, J. A.; Aust, S. D. Microsomal lipid peroxidation. In: Fleischer, S.; Parker, S., eds. Methods in enzymology. New York: Academic Press; 1978:52;302-310
    • Buege, J. A.; Aust, S. D. Microsomal lipid peroxidation. In: Fleischer, S.; Parker, S., eds. Methods in enzymology. New York: Academic Press; 1978:52;302-310.
  • 15
    • 0000470054 scopus 로고
    • Spectrophotometric studies, spectrophotometric constants for common hemoglobin derivatives in human, dog, and rabbit blood
    • Drabkin D.L., Austin J.M. Spectrophotometric studies, spectrophotometric constants for common hemoglobin derivatives in human, dog, and rabbit blood. J. Biol. Chem. 98:1932;719-733.
    • (1932) J. Biol. Chem. , vol.98 , pp. 719-733
    • Drabkin, D.L.1    Austin, J.M.2
  • 17
    • 0024803840 scopus 로고
    • Hyperglycemia can cause membrane lipid peroxidation and osmotic fragility in human red blood cells
    • Jain S.K. Hyperglycemia can cause membrane lipid peroxidation and osmotic fragility in human red blood cells. J. Biol. Chem. 264:(35):1989;21340-21345.
    • (1989) J. Biol. Chem. , vol.264 , Issue.35 , pp. 21340-21345
    • Jain, S.K.1
  • 18
    • 0021258409 scopus 로고
    • Lipid peroxidation, oxygen radicals, cell damage, and antioxidant therapy
    • Halliwell B., Gutteridge J.M.C. Lipid peroxidation, oxygen radicals, cell damage, and antioxidant therapy. Lancet. 1:1984;1396-1397.
    • (1984) Lancet , vol.1 , pp. 1396-1397
    • Halliwell, B.1    Gutteridge, J.M.C.2
  • 19
    • 0021250242 scopus 로고
    • Plasma ascorbate concentrations and red blood cell dehydroascorbate transport in patients with diabetes mellitus
    • Stankora L., Riddle M., Larned J. Plasma ascorbate concentrations and red blood cell dehydroascorbate transport in patients with diabetes mellitus. Metabolism. 33:1984;347-353.
    • (1984) Metabolism , vol.33 , pp. 347-353
    • Stankora, L.1    Riddle, M.2    Larned, J.3
  • 20
    • 0015910804 scopus 로고
    • Lipid peroxidation damage to cell components
    • Tappel A.L. Lipid peroxidation damage to cell components. Fed. Proc. 32:(8):1973;1870-1874.
    • (1973) Fed. Proc. , vol.32 , Issue.8 , pp. 1870-1874
    • Tappel, A.L.1
  • 21
    • 0031907677 scopus 로고    scopus 로고
    • Analytical aspects of antioxidants and free radical activity in clinical biochemistry
    • Rumley A.G., Paterson J.R. Analytical aspects of antioxidants and free radical activity in clinical biochemistry. Ann. Clin. Biochem. 35:1998;181-200.
    • (1998) Ann. Clin. Biochem. , vol.35 , pp. 181-200
    • Rumley, A.G.1    Paterson, J.R.2
  • 22
    • 0014060809 scopus 로고
    • Peroxidative hemolysis of red blood cells from patients with abetalipoproteinemia
    • Dodge J.R., Cohen G., Kayden H.J., Phillips G.B. Peroxidative hemolysis of red blood cells from patients with abetalipoproteinemia. J. Clin. Invest. 46:1967;357-368.
    • (1967) J. Clin. Invest. , vol.46 , pp. 357-368
    • Dodge, J.R.1    Cohen, G.2    Kayden, H.J.3    Phillips, G.B.4
  • 23
  • 24
    • 0023146553 scopus 로고
    • Mechanism of the cyanide-catalyzed oxidation of α-ketoalcohols
    • Mashino T., Fridovich I. Mechanism of the cyanide-catalyzed oxidation of α-ketoalcohols. Arch. Biochem. Biophys. 252:1987;163-170.
    • (1987) Arch. Biochem. Biophys. , vol.252 , pp. 163-170
    • Mashino, T.1    Fridovich, I.2
  • 25
    • 0023708392 scopus 로고
    • Hydroxyl radical production and autoxidative glycosylation. Glucose autoxidation as the cause of protein damage in the experimental glycation model of diabetes mellitus and ageing
    • Hunt J.V., Dean R.T., Wolff S.P. Hydroxyl radical production and autoxidative glycosylation. Glucose autoxidation as the cause of protein damage in the experimental glycation model of diabetes mellitus and ageing. Biochem. J. 15:1988;205-212.
    • (1988) Biochem. J. , vol.15 , pp. 205-212
    • Hunt, J.V.1    Dean, R.T.2    Wolff, S.P.3
  • 26
    • 0025021123 scopus 로고
    • Occurrence of lipoxygenase products in membranes of rabbit reticulocytes. Evidence for a role of the reticulocyte lipoxygenase in the maturation of red cells
    • Kuhn H., Brash A.R. Occurrence of lipoxygenase products in membranes of rabbit reticulocytes. Evidence for a role of the reticulocyte lipoxygenase in the maturation of red cells. J. Biol. Chem. 265:(3):1990;1454-1458.
    • (1990) J. Biol. Chem. , vol.265 , Issue.3 , pp. 1454-1458
    • Kuhn, H.1    Brash, A.R.2
  • 27
    • 0032563812 scopus 로고    scopus 로고
    • A function for lipoxygenase in programmed organelle degradation
    • van Leyen K., Duvoisin R.M., Engelhardt H., Wiedmann M. A function for lipoxygenase in programmed organelle degradation. Nature. 395:1998;392-395.
    • (1998) Nature , vol.395 , pp. 392-395
    • Van Leyen, K.1    Duvoisin, R.M.2    Engelhardt, H.3    Wiedmann, M.4
  • 28
    • 0034955787 scopus 로고    scopus 로고
    • Novel roles for glutathione in gene expression, cell death, and membrane transport of organic solutes
    • Hammond C.L., Lee T.K., Ballatori N. Novel roles for glutathione in gene expression, cell death, and membrane transport of organic solutes. J. Hepatol. 34:2001;946-954.
    • (2001) J. Hepatol. , vol.34 , pp. 946-954
    • Hammond, C.L.1    Lee, T.K.2    Ballatori, N.3
  • 29
    • 0033230043 scopus 로고    scopus 로고
    • Glutathione and its role in cellular functions
    • Sies H. Glutathione and its role in cellular functions. Free Radic. Biol. Med. 27:1999;916-921.
    • (1999) Free Radic. Biol. Med. , vol.27 , pp. 916-921
    • Sies, H.1
  • 31
    • 0024311551 scopus 로고
    • Impairment of glutathione metabolism in erythrocytes from patients with diabetes mellitus
    • Murakami K., Konda T., Ohtsuku Y., Fujwara Y., Shimada M., Kawakami R. Impairment of glutathione metabolism in erythrocytes from patients with diabetes mellitus. Metabolism. 38:1989;753-758.
    • (1989) Metabolism , vol.38 , pp. 753-758
    • Murakami, K.1    Konda, T.2    Ohtsuku, Y.3    Fujwara, Y.4    Shimada, M.5    Kawakami, R.6
  • 32
    • 0025612955 scopus 로고
    • Excessive excretion of 5-oxo proline and decreased levels of blood glutathione in type 2 diabetes mellitus
    • Forrerter T.F., Badaloo V., Bennett F.L., Jackson A.A. Excessive excretion of 5-oxo proline and decreased levels of blood glutathione in type 2 diabetes mellitus. Eur. J. Clin. Nutr. 44:1990;847-850.
    • (1990) Eur. J. Clin. Nutr. , vol.44 , pp. 847-850
    • Forrerter, T.F.1    Badaloo, V.2    Bennett, F.L.3    Jackson, A.A.4
  • 34
    • 0025077481 scopus 로고
    • Redox regulation of fos and jun DNA binding activity in vitro
    • Abate C., Patel L., Rauscher F.J., Curran T. Redox regulation of fos and jun DNA binding activity in vitro. Science. 249:1990;1157-1161.
    • (1990) Science , vol.249 , pp. 1157-1161
    • Abate, C.1    Patel, L.2    Rauscher, F.J.3    Curran, T.4
  • 35
    • 85031157770 scopus 로고    scopus 로고
    • Hwang, C.; Sinskey, A. J. The role of oxidation reduction potential in monitoring growth of cultured mammalian cells. In: Spier, R. E., ed. Production of biologicals from animals cells in culture. European society of animal cell technology. Burlington, MA: Butterworth-Heinemann; 1991:548-567
    • Hwang, C.; Sinskey, A. J. The role of oxidation reduction potential in monitoring growth of cultured mammalian cells. In: Spier, R. E., ed. Production of biologicals from animals cells in culture. European society of animal cell technology. Burlington, MA: Butterworth-Heinemann; 1991:548-567.
  • 37
    • 0027321246 scopus 로고
    • N-acetyl-cysteine inhibits apoptosis and decreases vital particles in HIV chronically infected U937 cells
    • Malorni W., Rivabene R., Santine M.T., Donelli G.N. N-acetyl-cysteine inhibits apoptosis and decreases vital particles in HIV chronically infected U937 cells. FEBS Lett. 327:1993;75-78.
    • (1993) FEBS Lett. , vol.327 , pp. 75-78
    • Malorni, W.1    Rivabene, R.2    Santine, M.T.3    Donelli, G.N.4
  • 39
    • 0037098867 scopus 로고    scopus 로고
    • Regulation of enzymatic lipid peroxidation: The interplay of peroxidizing and peroxide-reducing enzymes
    • Hartmut K., Astrid B. Regulation of enzymatic lipid peroxidation the interplay of peroxidizing and peroxide-reducing enzymes . Free Radic. Biol. Med. 33:2002;154-172.
    • (2002) Free Radic. Biol. Med. , vol.33 , pp. 154-172
    • Hartmut, K.1    Astrid, B.2
  • 40
    • 0034534421 scopus 로고    scopus 로고
    • Glutathione conjugation as bioactivation reaction
    • Van Bladeren P.J. Glutathione conjugation as bioactivation reaction. Chem. Biol. Interact. 129:2000;61-76.
    • (2000) Chem. Biol. Interact. , vol.129 , pp. 61-76
    • Van Bladeren, P.J.1
  • 42
    • 0029561598 scopus 로고
    • The Glutathione-S-transferase supergene family: Regulation of glutathione and the contribution of the isoenzymes to cancer chemoprotection and drug resistance
    • Hayes J.D., Pulford D.J. The Glutathione-S-transferase supergene family regulation of glutathione and the contribution of the isoenzymes to cancer chemoprotection and drug resistance . Crit. Rev. Biochem. Mol. Biol. 30:1995;445-600.
    • (1995) Crit. Rev. Biochem. Mol. Biol. , vol.30 , pp. 445-600
    • Hayes, J.D.1    Pulford, D.J.2
  • 43
    • 0030577732 scopus 로고    scopus 로고
    • Erythrocyte and plasma antioxidant activity in diabetes mellitus type 1
    • Ndahinana J., Dorchy H., Vertongen F. Erythrocyte and plasma antioxidant activity in diabetes mellitus type 1. Presse Med. 25:1996;188-192.
    • (1996) Presse Med. , vol.25 , pp. 188-192
    • Ndahinana, J.1    Dorchy, H.2    Vertongen, F.3
  • 44
    • 0023141806 scopus 로고
    • Erythrocyte lipid peroxidation and glutathione peroxidase in patients with diabetes mellitus
    • Uzel N., Sivas A., Uysal M. Erythrocyte lipid peroxidation and glutathione peroxidase in patients with diabetes mellitus. Horm. Metab. Res. 19:1987;89-90.
    • (1987) Horm. Metab. Res. , vol.19 , pp. 89-90
    • Uzel, N.1    Sivas, A.2    Uysal, M.3
  • 45
    • 0028930275 scopus 로고
    • Lipid peroxidation in insulin-dependent diabetic patients with early retina degenerative lesions: Effects of an oral zinc supplementation
    • Faure P., Benhamou P.Y., Perard A., Halimi S., Roussel A.M. Lipid peroxidation in insulin-dependent diabetic patients with early retina degenerative lesions effects of an oral zinc supplementation . Eur. J. Clin. Nutr. 49:1995;282-288.
    • (1995) Eur. J. Clin. Nutr. , vol.49 , pp. 282-288
    • Faure, P.1    Benhamou, P.Y.2    Perard, A.3    Halimi, S.4    Roussel, A.M.5
  • 46
    • 0025073714 scopus 로고
    • Changes in erythrocyte glutathione reductase in alloxan diabetes
    • Gupta B.L., Azam M., Baquer N.Z. Changes in erythrocyte glutathione reductase in alloxan diabetes. Biochem. Intern. 21:1990;725-731.
    • (1990) Biochem. Intern. , vol.21 , pp. 725-731
    • Gupta, B.L.1    Azam, M.2    Baquer, N.Z.3
  • 47
    • 0027714623 scopus 로고
    • Glutathione-related detoxification functions in streptozotocin-induced diabetic rats
    • Saito-Yamanaka N., Yamanaka H., Nagasawa S. Glutathione-related detoxification functions in streptozotocin-induced diabetic rats. J. Vet. Med. Sci. 55:1993;991-994.
    • (1993) J. Vet. Med. Sci. , vol.55 , pp. 991-994
    • Saito-Yamanaka, N.1    Yamanaka, H.2    Nagasawa, S.3
  • 48
    • 0020427486 scopus 로고
    • Biology of disease: Free radicals and tissue injury
    • Freeman B.A., Crapo J.D. Biology of disease free radicals and tissue injury . Lab. Invest. 47:1982;412-426.
    • (1982) Lab. Invest. , vol.47 , pp. 412-426
    • Freeman, B.A.1    Crapo, J.D.2
  • 50
    • 0347391694 scopus 로고    scopus 로고
    • Effect of alloxan-induced mild insulin-dependent diabetic mellitus on rat erythrocyte cytosolic dehydrogenases
    • Gupta D.K., Ahmed F., Suhail M. Effect of alloxan-induced mild insulin-dependent diabetic mellitus on rat erythrocyte cytosolic dehydrogenases. Ind. J. Exp. Biol. 34:1996;262-263.
    • (1996) Ind. J. Exp. Biol. , vol.34 , pp. 262-263
    • Gupta, D.K.1    Ahmed, F.2    Suhail, M.3
  • 51
    • 0036596625 scopus 로고    scopus 로고
    • Endogenous oxidative stress: Relationship to aging, longevity, and caloric restriction
    • Barja G. Endogenous oxidative stress relationship to aging, longevity, and caloric restriction . Ageing Res. Rev. 1:2002;397-411.
    • (2002) Ageing Res. Rev. , vol.1 , pp. 397-411
    • Barja, G.1
  • 52
    • 0031973526 scopus 로고    scopus 로고
    • Glutathione and glucose-6-phosphate dehydrogenase deficiency can increase protein glycosylation
    • Jain S.K. Glutathione and glucose-6-phosphate dehydrogenase deficiency can increase protein glycosylation. Free Radic Biol. Med. 24:1998;197-201.
    • (1998) Free Radic Biol. Med. , vol.24 , pp. 197-201
    • Jain, S.K.1
  • 53
    • 0025055081 scopus 로고
    • Identification of fructose-3-phosphate in the lens of diabetic rats
    • Szwergold B.S., Kappler F., Brown T.R. Identification of fructose-3-phosphate in the lens of diabetic rats. Science. 247:1990;451-454.
    • (1990) Science , vol.247 , pp. 451-454
    • Szwergold, B.S.1    Kappler, F.2    Brown, T.R.3
  • 54
    • 0025006127 scopus 로고    scopus 로고
    • Peteson, A.; Szwergold, B. S.; Kappler, F.; Weingarten, M.; Brown, T. R. Identification of Sorbitol-3-phosphate and Fructose-3-phosphate in normal and diabetic human erythrocytes. J. Biol. Chem. 265(29):17424-17427; 1990
    • Peteson, A.; Szwergold, B. S.; Kappler, F.; Weingarten, M.; Brown, T. R. Identification of Sorbitol-3-phosphate and Fructose-3-phosphate in normal and diabetic human erythrocytes. J. Biol. Chem. 265(29):17424-17427; 1990.
  • 55
    • 0026482539 scopus 로고
    • Glycation (nonenzymatic glycosylation) inactivates glutathione reductase
    • Blakytny R., Harding J.J. Glycation (nonenzymatic glycosylation) inactivates glutathione reductase. Biochem. J. 288:1972;303-307.
    • (1972) Biochem. J. , vol.288 , pp. 303-307
    • Blakytny, R.1    Harding, J.J.2
  • 57
    • 0020674495 scopus 로고
    • Effect of experimental anaemia on red cell GSH and enzyme activities in guinea pig and rabbit
    • Suzuki M., Kataoka T. Effect of experimental anaemia on red cell GSH and enzyme activities in guinea pig and rabbit. Comp. Biochem. Physiol. B. 75:(1):1983;5-8.
    • (1983) Comp. Biochem. Physiol. B , vol.75 , Issue.1 , pp. 5-8
    • Suzuki, M.1    Kataoka, T.2
  • 58
    • 0003319715 scopus 로고
    • Effect of plant and animal tissue lesions on superoxide dismutase activities
    • A.M. Michelson, J.M. McCord, & I. Fridovich. New York: Academic Press
    • Matkovics B. Effect of plant and animal tissue lesions on superoxide dismutase activities. Michelson A.M., McCord J.M., Fridovich I. Superoxide and superoxide dismutases. 1977;501-515 Academic Press, New York.
    • (1977) Superoxide and superoxide dismutases , pp. 501-515
    • Matkovics, B.1
  • 61
    • 0024951642 scopus 로고
    • Antioxidant enzyme status and lipid peroxidation in various tissues of diabetic and starved rats
    • Asayama K., Hayashibe H., Dobashi K., Niitsu T., Miyao A., Kato K. Antioxidant enzyme status and lipid peroxidation in various tissues of diabetic and starved rats. Diabetes Res. 12:1989;85-91.
    • (1989) Diabetes Res. , vol.12 , pp. 85-91
    • Asayama, K.1    Hayashibe, H.2    Dobashi, K.3    Niitsu, T.4    Miyao, A.5    Kato, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.