Influence of process parameters of high-pressure emulsification method on the properties of pilocarpine-loaded nanoparticles

Journal of Microencapsulation

Volumn 20, Issue 4, 2003, Pages 449-458

  Yoncheva, K ^a,b   Vandervoort, J ^b   Ludwig, A ^b  

^a MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

^b UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

High pressure emulsification; Nanoparticle; Ocular; Pilocarpine; Poly(lactide co glycolide)

Indexed keywords

CARBOMER; NANOPARTICLE; PILOCARPINE; POLOXAMER; POLYGLACTIN; SOLVENT; STABILIZING AGENT; WATER;

ARTICLE; ATMOSPHERIC PRESSURE; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG RELEASE; EMULSION; EVAPORATION; PARTICLE SIZE;

ACRYLIC RESINS; DRUG CARRIERS; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; EMULSIONS; EXCIPIENTS; HUMANS; MICROSPHERES; MIOTICS; NANOTECHNOLOGY; OPHTHALMIC SOLUTIONS; PARTICLE SIZE; PILOCARPINE; POLOXAMER; POLYGLACTIN 910; POLYVINYL ALCOHOL; PRESSURE;

EID: 0038496899     PISSN: 02652048     EISSN: None     Source Type: Journal    
DOI: 10.1080/0265204021000058429     Document Type: Article

References (19)

1. Bachmann, D., Brandl, M. and Gregoriadis, G., 1993, Preparation of liposomes using a Mini-Lab 8.30 H high-pressure homogenizer. International Journal of Pharmaceutics, 91, 69-74.
2. Bodmeier, R. and McGinity, J. W., 1987, The preparation and evaluation of drug-containing poly(DL-lactide) microspheres formed by the solvent evaporation method. Pharmaceutical Research, 4, 465-471.
3. Calvo, P., Alonso, M. J., Vita-Jato, J. L. and Robinson, J. R., 1996, Improved ocular bioavailability of indomethacin by novel ocular drug carriers. Journal of Pharmacy and Pharmacology, 48, 1147-1152.
4. Chen, R. H., Win, H. P. and Fang, H. J., 2001, Vesicle size, size distribution, stability, and rheological properties of liposomes coated with water-soluble chitosans of different molecular weights and concentrations. Journal of liposome research, 11, 211-228.
5. Conti, B., Genta, I., Modena, T. and Pavanetto, F., 1995, Investigation on process parameters involved in polylactic-co-glycolic microspheres preparation. Drug Development and Industrial Pharmacy, 21, 615-622.
6. Coombes, A. G. A., Rafati, H., Adler, J., Holland, J. and Davis, S. S., 1997, Protein-loaded poly(D,L-lactide-co-glycolide) microparticles for oral administration: formulation, structural and release characteristics. Journal of Controlled Release, 43, 89-102.
7. Gurny, R., Ibrahim, H., Aebi, A., Buri, P., Wilson, C. G., Washington, N., Edman, P. and Camber, O., 1987, Design and evaluation of controlled release system for the eye. Journal of Controlled Release, 6, 367-373.
8. Jalil, R. and Nixon, J. R., 1990, Biodegradable poly(lactic acid) and poly(lactide-coglycolide) microcapsules: problems associated with preparative techniques and release properties. Journal of Microencapsulation, 7, 297-325.
9. Jumaa, M. and Muller, B. W., 1998, The effect of oil components and homogenization conditions on the physicochemical properties and stability of parenteral fat emulsions. International Journal of Pharmaceutics, 163, 81-89.
10. Lamprecht, A., Ubrich, N., Hombreiro Perez, M., Lehr, C.M., Hoffman, M. and Maincent, P., 2000, Influences of process parameters on nanoparticle preparation performed by a double emulsion pressure homogenization technique. International Journal of Pharmaceutics, 196, 177-182.
11. Ogawa, Y., Yamamoto, M., Okada, H., Yashiki, T. and Shimamoto, T., 1988, A new technique to efficiently entrap leuprolide acetate into microcapsules of polylactic acid or copoly(lactic/glycolic) acid. Chemical and Pharmaceutical Bulletin, 36, 1095-1103.
12. Schwarz, C., Mehnert, W., Lucks, J. S. and Muller, R. H., 1994, Solid lipid nanoparticles (SLN) for controlled drug delivery. I. Production, characterization and sterilization. Journal of Controlled Release, 30, 83-96.
13. Soriano, I., Delgado, A., Diaz, R. V. and Evora, C., 1995, Use of surfactants in polylactic acid protein microspheres. Drug Development and Industrial Pharmacy, 21, 549-558.
14. Teixeira, H., Dubernet, C., Puisieux, F., Benita, S. and Couvreur, P., 1999, Submicron cationic emulsions as a new delivery system for oligonucleotides. Pharmaceutical Research, 16, 30-36.
15. Tice, T. R., Mason, D. W. and Gilley, R. M., 1989, Clinical use and future of parenteral microsphere delivery systems. In Novel Drug Delivery, edited by G. F. Prescott and W. S. Nimmo (Chichester: Wiley), pp. 223-235.
16. Ueda, M. and Kreuter, J., 1997, Optimization of the preparation of loperamide-loaded poly(L-lactide) nanoparticles by high pressure emulsification-solvent evaporation. Journal of Microencapsulation, 14, 593-605.
17. Washington, C. and Davis, S. S., 1988, The production of parenteral feeding emulsions by Microfluidizer. International Journal of Pharmaceutics, 44, 169-176.
18. Zimmer, A. and Kreuter, J., 1995, Microspheres and nanoparticles used in ocular delivery systems. Advanced Drug Delivery Reviews, 16, 61-73.
19. Zimmer, A., Chetoni, P., Saettone, M., Zerbe, H. and Kreuter, J., 1995, Evaluation of pilocarpine-loaded albumin particles as controlled drug delivery systems for the eye. II. Co-administration with bioadhesive and viscous polymers. Journal of Controlled Release, 33, 31-46.