Construction and in vivo infection of a new simian/human immunodeficiency virus chimera containing the reverse transcriptase gene and the 3′ half of the genomic region of human immunodeficiency virus type 1

Journal of General Virology

Volumn 84, Issue 7, 2003, Pages 1663-1669

  Akiyama, Hisashi ^a   Ido, Eiji ^a   Akahata, Wataru ^a   Kuwata, Takeo ^a   Miura, Tomoyuki ^a   Hayami, Masanori ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; EMIVIRINE; NEF PROTEIN; POL PROTEIN; REV PROTEIN; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; TRANSACTIVATOR PROTEIN; VIRUS ANTIBODY; VIRUS DNA; VIRUS ENVELOPE PROTEIN; VPR PROTEIN; VPU PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; CHIMERA; CONTROLLED STUDY; DNA DETERMINATION; GENE CONSTRUCT; GENE STRUCTURE; GENETIC CODE; GENETIC LINE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VIVO STUDY; INOCULATION; LYMPHOID CELL LINE; MACACA; NONHUMAN; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROVIRUS; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS; T LYMPHOCYTE; VIRUS GENOME; VIRUS INFECTION; VIRUS ISOLATION; VIRUS LOAD; VIRUS REPLICATION;

3' UNTRANSLATED REGIONS; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; DISEASE MODELS, ANIMAL; GENOME, VIRAL; HIV INFECTIONS; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; LEUKOCYTES, MONONUCLEAR; MACACA MULATTA; RECOMBINANT FUSION PROTEINS; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; VIRAL ENVELOPE PROTEINS; VIRUS REPLICATION;

ANIMALIA; DNA VIRUSES; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA; MACACA MULATTA; RNA VIRUSES; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS; SIMIAN-HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0038496858     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.18843-0     Document Type: Article

References (29)

1. Adachi, A., Gendelman, H. E., Koenig, S., Folks, T., Willey, R., Rabson, A.&Martin, M. A. (1986). Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J Virol 59, 284-291.
2. Akari, H., Mori, K., Terao, K., Otani, I., Fukasawa, M., Mukai, R.&Yoshikawa, Y. (1996). In vitro immortalization of Old World monkey T lymphocytes with herpesvirus saimiri: susceptibility to infection with simian immunodeficiency viruses. Virology 218, 382-388.
3. Baba, M., Shigeta, S., Yuasa, S.&7 other authors (1994). Preclinical evaluation of MKC-442, a highly potent and specific inhibitor of human immunodeficiency virus type 1 in vitro. Antimicrob Agents Chemother 38, 688-692.
4. Bogers, W. M., Dubbes, R., ten Haaft, P.&12 other authors (1997). Comparison of in vitro and in vivo infectivity of different clade B HIV-1 envelope chimeric simian/human immunodeficiency viruses in Macaca mulatta. Virology 236, 110-117.
5. Clapham, P. R., Weiss, R. A., Dalgleish, A. G., Exley, M., Whitby, D.&Hogg, N. (1987). Human immunodeficiency virus infection of monocytic and T-lymphocytic cells: receptor modulation and differentiation induced by phorbol ester. Virology 158, 44-51.
6. Daniel, M. D., Kirchhoff, F., Czajak, S. C., Sehgal, P. K. & Desrosiers, R. C. (1992). Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. Science 258, 1938-1941.
7. Fultz, P. N., McClure, H. M., Daugharty, H., Brodie, A., McGrath, C. R., Swenson, B.&Francis, D. P. (1986). Vaginal transmission of human immunodeficiency virus (HIV) to a chimpanzee. J Infect Dis 154, 896-900.
8. Gajdusek, D. C., Amyx, H. L., Gibbs, C. J., Jr&7 other authors (1985). Infection of chimpanzees by human T-lymphotropic retroviruses in brain and other tissues from AIDS patients. Lancet i, 55-56.
9. Harouse, J. M., Gettie, A., Tan, R. C., Blanchard, J. & Cheng-Mayer, C. (1999). Distinct pathogenic sequela in rhesus macaques infected with CCR5 or CXCR4 utilizing SHIVs. Science 284, 816-819.
10. Hayami, M., Igarashi, T., Kuwata, T., Ui, M., Haga, T., Ami, Y., Shinohara, K.&Honda, M. (1999). Gene-mutated HIV-1/SIV chimeric viruses as AIDS live attenuated vaccines for potential human use. Leukemia 13 (Suppl. 1), S42-S47.
11. mac chimeric virus having tat, rev, vpu, env and nef of HIV type 1 in macaque monkeys. AIDS Res Hum Retroviruses 10, 1021-1029.
12. Igarashi, T., Kuwata, T., Takehisa, J.&7 other authors (1996). Genomic and biological alteration of a human immunodeficiency virus type 1 (HIV-1)-simian immunodeficiency virus strain mac chimera, with HIV-1 Env, recovered from a long-term carrier monkey. J Gen Virol 77, 1649-1658.
13. + T cells and AIDS in pig-tailed macaques. J Virol 70, 3189-3197.
14. Joag, S. V., Li, Z., Foresman, L.&10 other authors (1997). Characterization of the pathogenic KU-SHIV model of acquired immunodeficiency syndrome in macaques. AIDS Res Hum Retroviruses 13, 635-645.
15. Kestler, H. W. D., III, Ringler, D. J., Mori, K., Panicali, D. L., Sehgal, P. K., Daniel, M. D.&Desrosiers, R. C. (1991). Importance of the nef gene for maintenance of high virus loads and for development of AIDS. Cell 65, 651-662.
16. Kozyrev, I. L., Miura, T., Takemura, T., Kuwata, T., Ui, M., Ibuki, K., Iida, T.&Hayami, M. (2002). Co-expression of interleukin-5 influences replication of simian/human immunodeficiency viruses in vivo. J Gen Virol 83, 1183-1188.
17. Kuwata, T., Igarashi, T., Ido, E., Jin, M., Mizuno, A., Chen, J.&Hayami, M. (1995). Construction of human immunodeficiency virus 1/simian immunodeficiency virus strain mac chimeric viruses having vpr and/or nef of different parental origins and their in vitro and in vivo replication. J Gen Virol 76, 2181-2191.
18. Letvin, N. L., Daniel, M. D., Sehgal, P. K.&7 other authors (1985). Induction of AIDS-like disease in macaque monkeys with T-cell tropic retrovirus STLV-III. Science 230, 71-73.
19. mac virus that expresses the HIV-1 envelope glycoproteins. J Acquir Immune Defic Syndr 5, 639-646.
20. mac. J Virol 62, 4691-4696.
21. Novembre, F. J., Saucier, M., Anderson, D. C.&7 other authors (1997). Development of AIDS in a chimpanzee infected with human immunodeficiency virus type 1. J Virol 71, 4086-4091.
22. Pauwels, R., Balzarini, J., Baba, M., Snoeck, R., Schols, D., Herdewijn, P., Desmyter, J.&De Clercq, E. (1988). Rapid and automated tetrazolium-based colorimetric assay for the detection of anti-HIV compounds. J Virol Methods 20, 309-321.
23. Reimann, K. A., Li, J. T., Veazey, R., Halloran, M., Park, I. W., Karlsson, G. B., Sodroski, J.&Letvin, N. L. (1996). A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys. J Virol 70, 6922-6928.
24. Shibata, R., Kawamura, M., Sakai, H., Hayami, M., Ishimoto, A.&Adachi, A. (1991). Generation of a chimeric human and simian immunodeficiency virus infectious to monkey peripheral blood mononuclear cells. J Virol 65, 3514-3520.
25. Überla, K., Stahl-Hennig, C., Bottiger, D.&7 other authors (1995). Animal model for the therapy of acquired immunodeficiency syndrome with reverse transcriptase inhibitors. Proc Natl Acad Sci U S A 92, 8210-8214.
26. Ui, M., Kuwata, T., Igarashi, T.&9 other authors (1999). Protection of macaques against a SHIV with a homologous HIV-1 Env and a pathogenic SHIV-89.6P with a heterologous Env by vaccination with multiple gene-deleted SHIVs. Virology 265, 252-263.
27. + T cell depletion and viral replication in SIV infection. Science 280, 427-431.
28. Willey, R. L., Smith, D. H., Lasky, L. A., Theodore, T. S., Earl, P. L., Moss, B., Capon, D. J.&Martin, M. A. (1988). In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity. J Virol 62, 139-147.
29. Yuasa, S., Sadakata, Y., Takashima, H., Sekiya, K., Inouye, N., Ubasawa, M.&Baba, M. (1993). Selective and synergistic inhibition of human immunodeficiency virus type 1 reverse transcriptase by a non-nucleoside inhibitor, MKC-442. Mol Pharmacol 44, 895-900.