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Volumn 29, Issue 2, 2003, Pages 409-426

Update on disease-modifying antirheumatic drugs in the treatment of systemic sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ACETYLSALICYLIC ACID; ALPHA INTERFERON; AMINOBENZOIC ACID; ANTIRHEUMATIC AGENT; BOSENTAN; BOVINE COLLAGEN TYPE 1; CAPTOPRIL; CHLORAMBUCIL; COLLAGEN TYPE 1; CYCLOFENIL; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; CYTOKINE ANTIBODY; DIMETHYL SULFOXIDE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIPYRIDAMOLE; FLUOROURACIL; GAMMA INTERFERON; KETOTIFEN; METHOTREXATE; PENICILLAMINE; PREDNISOLONE; PREDNISONE; PROSTACYCLIN; RELAXIN; THYMOCYTE ANTIBODY; TRANSFORMING GROWTH FACTOR BETA ANTIBODY; UNCLASSIFIED DRUG; UNIPROST;

EID: 0038461984     PISSN: 0889857X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0889-857X(03)00026-7     Document Type: Review
Times cited : (26)

References (51)
  • 1
    • 0028920576 scopus 로고
    • Guidelines for clinical trials in systemic sclerosis (scleroderma). I. Disease-modifying interventions
    • White B, Bauer EA, Goldsmith LA, et al. Guidelines for clinical trials in systemic sclerosis (scleroderma). I. Disease-modifying interventions. Arthritis Rheum 1995;38(3):351-60.
    • (1995) Arthritis Rheum , vol.38 , Issue.3 , pp. 351-360
    • White, B.1    Bauer, E.A.2    Goldsmith, L.A.3
  • 2
    • 0033758222 scopus 로고    scopus 로고
    • Skin thickness score as a predictor and correlate of outcome in systemic sclerosis: High-dose versus low-dose penicillamine trial
    • Clements PJ, Hurwitz EL, Wong WK, et al. Skin thickness score as a predictor and correlate of outcome in systemic sclerosis: high-dose versus low-dose penicillamine trial. Arthritis Rheum 2000;43(11):2445-54.
    • (2000) Arthritis Rheum , vol.43 , Issue.11 , pp. 2445-2454
    • Clements, P.J.1    Hurwitz, E.L.2    Wong, W.K.3
  • 3
    • 0020382052 scopus 로고
    • D-penicillamine therapy in progressive systemic sclerosis (scleroderma)
    • Steen VD, Medsger Jr TA, Rodnan GP, D-penicillamine therapy in progressive systemic sclerosis (scleroderma). Ann Intern Med 1982;97:652-9.
    • (1982) Ann Intern Med , vol.97 , pp. 652-659
    • Steen, V.D.1    Medsger T.A., Jr.2    Rodnan, G.P.3
  • 4
    • 0024405579 scopus 로고
    • Immunosuppression with chlorambucil, versus placebo, for scleroderma
    • Furst DE, Clements PJ, Hillis S, et al. Immunosuppression with chlorambucil, versus placebo, for scleroderma. Arthritis Rheum 1989;32:584-93.
    • (1989) Arthritis Rheum , vol.32 , pp. 584-593
    • Furst, D.E.1    Clements, P.J.2    Hillis, S.3
  • 5
    • 0033064099 scopus 로고    scopus 로고
    • High-dose versus low-dose D-penicillamine in early diffuse systemic sclerosis: Analysis of a two year, double-blind, randomized, controlled clinical trial
    • Clements PJ, Furst DE, Wong WK, et al. High-dose versus low-dose D-penicillamine in early diffuse systemic sclerosis: analysis of a two year, double-blind, randomized, controlled clinical trial. Arthritis Rheum 1999;42(6):1194-203.
    • (1999) Arthritis Rheum , vol.42 , Issue.6 , pp. 1194-1203
    • Clements, P.J.1    Furst, D.E.2    Wong, W.K.3
  • 6
    • 0026601642 scopus 로고
    • Treatment of systemic sclerosis with extracorporeal photochemistherapy
    • Rook AH, Freundlich B, Jegasothy BV, et al. Treatment of systemic sclerosis with extracorporeal photochemistherapy. Arch Dermatol 1992;128:337-46.
    • (1992) Arch Dermatol , vol.128 , pp. 337-346
    • Rook, A.H.1    Freundlich, B.2    Jegasothy, B.V.3
  • 7
    • 19244381445 scopus 로고    scopus 로고
    • Correlates of the disability index of the Health Assessment Questionnaire. A measure of functional impairment in systemic sclerosis (SSc)
    • Clements PJ, Wong WK, Hurwitz EL, et al. Correlates of the disability index of the Health Assessment Questionnaire. A measure of functional impairment in systemic sclerosis (SSc). Arthritis Rheum 1999;42:2372-80.
    • (1999) Arthritis Rheum , vol.42 , pp. 2372-2380
    • Clements, P.J.1    Wong, W.K.2    Hurwitz, E.L.3
  • 8
    • 0035080134 scopus 로고    scopus 로고
    • The disability index of the Health Assessment Questionnaire is a predictor and correlate of outcome in the high-dose vs low-dose penicillamine in systemic sclerosis trial
    • Clements PJ, Wong WK, Hurwitz EL, et al. The disability index of the Health Assessment Questionnaire is a predictor and correlate of outcome in the high-dose vs low-dose penicillamine in systemic sclerosis trial. Arthritis Rheum 2001;44:653-61.
    • (2001) Arthritis Rheum , vol.44 , pp. 653-661
    • Clements, P.J.1    Wong, W.K.2    Hurwitz, E.L.3
  • 10
    • 0034808135 scopus 로고    scopus 로고
    • Reliability, validity, and responsiveness of the six-minute walk test in patients with heart failure
    • Demers C, McKelvie RS, Negassa A. Reliability, validity, and responsiveness of the six-minute walk test in patients with heart failure. Am Heart J 2001;142(4):698-703.
    • (2001) Am Heart J , vol.142 , Issue.4 , pp. 698-703
    • Demers, C.1    McKelvie, R.S.2    Negassa, A.3
  • 11
    • 0033753670 scopus 로고    scopus 로고
    • Rational therapy in the treatment of systemic sclerosis
    • Furst DE. Rational therapy in the treatment of systemic sclerosis. Curr Opin Rheumatol 2000;12(6):540-4.
    • (2000) Curr Opin Rheumatol , vol.12 , Issue.6 , pp. 540-544
    • Furst, D.E.1
  • 12
    • 0035171979 scopus 로고    scopus 로고
    • Big endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension
    • Rubens C, Ewert R, Halank M, et al. Big endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension. Chest 2001;120(5):1562-9.
    • (2001) Chest , vol.120 , Issue.5 , pp. 1562-1569
    • Rubens, C.1    Ewert, R.2    Halank, M.3
  • 13
    • 0024794487 scopus 로고
    • Decreased arterial wall prostaglandin production in neonatal calves with severe chronic pulmonary hypertension
    • Badesch DB, Orton EC, Zapp LM, et al. Decreased arterial wall prostaglandin production in neonatal calves with severe chronic pulmonary hypertension. Am J Respir Cell Mol Biol 1989;1:489-98.
    • (1989) Am J Respir Cell Mol Biol , vol.1 , pp. 489-498
    • Badesch, D.B.1    Orton, E.C.2    Zapp, L.M.3
  • 14
    • 17144452827 scopus 로고    scopus 로고
    • Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial
    • Badesch DB, Tapson VF, McGoon MD, et al. Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease. A randomized, controlled trial. Ann Intern Med 2000;132(6):425-34.
    • (2000) Ann Intern Med , vol.132 , Issue.6 , pp. 425-434
    • Badesch, D.B.1    Tapson, V.F.2    McGoon, M.D.3
  • 15
    • 0032739285 scopus 로고    scopus 로고
    • Effects of long-term infusion of prostacyclin on exercise performance in patients with primary pulmonary hypertension
    • Wax D, Garofano R, Barst RJ. Effects of long-term infusion of prostacyclin on exercise performance in patients with primary pulmonary hypertension. Chest 1999;116:914-20.
    • (1999) Chest , vol.116 , pp. 914-920
    • Wax, D.1    Garofano, R.2    Barst, R.J.3
  • 16
    • 0034804704 scopus 로고    scopus 로고
    • Medical therapy of pulmonary hypertension. The prostacyclin
    • Galie N, Manes A, Branzi A. Medical therapy of pulmonary hypertension. The prostacyclin. Clin Chest Med 2001;22(3):529-37.
    • (2001) Clin Chest Med , vol.22 , Issue.3 , pp. 529-537
    • Galie, N.1    Manes, A.2    Branzi, A.3
  • 17
    • 0037086133 scopus 로고    scopus 로고
    • Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: A double-blind, randomized, placebo-controlled trial
    • Simonneau G, Barst RJ, Galie N, et al. Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: a double-blind, randomized, placebo-controlled trial. Am J Respir Crit Care Med 2002;165(6):800-4.
    • (2002) Am J Respir Crit Care Med , vol.165 , Issue.6 , pp. 800-804
    • Simonneau, G.1    Barst, R.J.2    Galie, N.3
  • 18
    • 0035818316 scopus 로고    scopus 로고
    • Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: A randomized placebo-controlled study
    • Channick RN, Simonnea G, Sitbon O, et al. Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomized placebo-controlled study. Lancet 2001;358:1119-23.
    • (2001) Lancet , vol.358 , pp. 1119-1123
    • Channick, R.N.1    Simonnea, G.2    Sitbon, O.3
  • 19
    • 0037149718 scopus 로고    scopus 로고
    • Bosentan therapy for pulmonary arterial hypertension
    • Rubin LF, Badesch DB, Barst RJ. Bosentan therapy for pulmonary arterial hypertension. NEJM 2002;346:896-903.
    • (2002) NEJM , vol.346 , pp. 896-903
    • Rubin, L.F.1    Badesch, D.B.2    Barst, R.J.3
  • 20
    • 0032982157 scopus 로고    scopus 로고
    • Downregulation of intercellular adhesion molecule-1 expression on human synovial fibroblasts by endothelin-1
    • Iwabuchi H, Kasama T, Hanaoka R. Downregulation of intercellular adhesion molecule-1 expression on human synovial fibroblasts by endothelin-1. J Rheumatol 1999;26(3):522-31.
    • (1999) J Rheumatol , vol.26 , Issue.3 , pp. 522-531
    • Iwabuchi, H.1    Kasama, T.2    Hanaoka, R.3
  • 21
    • 0029953420 scopus 로고    scopus 로고
    • Scleroderma renal crisis
    • Steen VD. Scleroderma renal crisis. Rheum Dis Clin North Am 1996;22(4):861-78.
    • (1996) Rheum Dis Clin North Am , vol.22 , Issue.4 , pp. 861-878
    • Steen, V.D.1
  • 22
    • 0019390793 scopus 로고
    • Clinical course of patients with scleroderma renal crisis treated with captopril
    • Zawada Jr ET, Clements PJ, Furst DA, et al. Clinical course of patients with scleroderma renal crisis treated with captopril. Nephron 1981;27:74-8.
    • (1981) Nephron , vol.27 , pp. 74-78
    • Zawada E.T., Jr.1    Clements, P.J.2    Furst, D.A.3
  • 23
    • 0021354889 scopus 로고
    • Captopril in the treatment of scleroderma renal crisis
    • Thurm RH, Alexander JC. Captopril in the treatment of scleroderma renal crisis. Arch Intern Med 1984;144:733-55.
    • (1984) Arch Intern Med , vol.144 , pp. 733-755
    • Thurm, R.H.1    Alexander, J.C.2
  • 24
    • 0022385396 scopus 로고
    • Use of captopril as early therapy for renal scleroderma: A prospective study
    • Beckett VL, Donadio JV, Brennan Jr LA, et al. Use of captopril as early therapy for renal scleroderma: A prospective study. Mayo Clin Proc 1985;60:763-71.
    • (1985) Mayo Clin Proc , vol.60 , pp. 763-771
    • Beckett, V.L.1    Donadio, J.V.2    Brennan L.A., Jr.3
  • 25
    • 0025152770 scopus 로고
    • Outcome of renal crisis in systemic sclerosis: Relation to availability of angiotensin converting enzyme (ACE) inhibitors
    • Steen VD, Costantino JP, Shapiro AP, et al. Outcome of renal crisis in systemic sclerosis: relation to availability of angiotensin converting enzyme (ACE) inhibitors. Ann Intern Med 1990;113:352-7.
    • (1990) Ann Intern Med , vol.113 , pp. 352-357
    • Steen, V.D.1    Costantino, J.P.2    Shapiro, A.P.3
  • 26
    • 0033771114 scopus 로고    scopus 로고
    • Long-term outcomes of scleroderma renal crisis
    • Steen VD, Medsger Jr TA. Long-term outcomes of scleroderma renal crisis. Ann Intern Med 2000;17:600-3.
    • (2000) Ann Intern Med , vol.17 , pp. 600-603
    • Steen, V.D.1    Medsger T.A., Jr.2
  • 27
    • 0027314630 scopus 로고
    • Cyclophosphamide and low-dose prednisone therapy in patients with systemic sclerosis (scleroderma) with interstitial lung disease
    • Silver RM, Warrick JH, Kinsella MB, et al. Cyclophosphamide and low-dose prednisone therapy in patients with systemic sclerosis (scleroderma) with interstitial lung disease. J Rheumatol 1993;20:838-44.
    • (1993) J Rheumatol , vol.20 , pp. 838-844
    • Silver, R.M.1    Warrick, J.H.2    Kinsella, M.B.3
  • 28
    • 0034691244 scopus 로고    scopus 로고
    • Cyclophosphamide is associated with pulmonary function and survival benefit in patients with scleroderma and alveolitis
    • White B, Moore W, Wigley F, et al. Cyclophosphamide is associated with pulmonary function and survival benefit in patients with scleroderma and alveolitis. Ann Int Med 2000;132:947-54.
    • (2000) Ann Int Med , vol.132 , pp. 947-954
    • White, B.1    Moore, W.2    Wigley, F.3
  • 29
    • 0029867337 scopus 로고    scopus 로고
    • Comparison of methotrexate with placebo in the treatment of systemic sclerosis: A 24 week randomized double-blind trial, followed by a 24 week observational trial
    • Van den Hoogen FH, Boerbooms AM, Swaak AJ, et al. Comparison of methotrexate with placebo in the treatment of systemic sclerosis: a 24 week randomized double-blind trial, followed by a 24 week observational trial. Br J Rheumatol 1996;35(4):364-72.
    • (1996) Br J Rheumatol , vol.35 , Issue.4 , pp. 364-372
    • Van den Hoogen, F.H.1    Boerbooms, A.M.2    Swaak, A.J.3
  • 30
    • 0034970031 scopus 로고    scopus 로고
    • A randomized controlled trial of methotrexate versus placebo in early diffuse scleroderma
    • Pope J, Bellamy N, Seibold J, et al. A randomized controlled trial of methotrexate versus placebo in early diffuse scleroderma. Arthritis Rheum 2001;44:1351-8.
    • (2001) Arthritis Rheum , vol.44 , pp. 1351-1358
    • Pope, J.1    Bellamy, N.2    Seibold, J.3
  • 31
    • 0025012321 scopus 로고
    • 5-Fluorouracil in the treatment of scleroderma: A randomized, double-blind, placebo-controlled international collaborative study
    • Casas JA, Saway PA, Villarreal I, et al. 5-Fluorouracil in the treatment of scleroderma: a randomized, double-blind, placebo-controlled international collaborative study. Ann Rheum Dis 1990;49:926-8.
    • (1990) Ann Rheum Dis , vol.49 , pp. 926-928
    • Casas, J.A.1    Saway, P.A.2    Villarreal, I.3
  • 32
    • 0035017415 scopus 로고    scopus 로고
    • Phase I/II trial of autologous stem cell transplantation in systemic sclerosis: Procedure related mortality and impact on skin disease
    • Binks M, Passweg JR, Furst D, et al. Phase I/II trial of autologous stem cell transplantation in systemic sclerosis: procedure related mortality and impact on skin disease. Ann Rheum Dis 2001;60(6):577-84.
    • (2001) Ann Rheum Dis , vol.60 , Issue.6 , pp. 577-584
    • Binks, M.1    Passweg, J.R.2    Furst, D.3
  • 33
    • 85086684350 scopus 로고    scopus 로고
    • High-dose immunosuppressive therapy with autologous stem cell transplantation for systemic sclerosis
    • Furst DE, McSweeney PA, Nash R, et al. High-dose immunosuppressive therapy with autologous stem cell transplantation for systemic sclerosis. Blood 2002;100:1602-10.
    • (2002) Blood , vol.100 , pp. 1602-1610
    • Furst, D.E.1    McSweeney, P.A.2    Nash, R.3
  • 34
    • 0036228253 scopus 로고    scopus 로고
    • Stem cell transplantation for autoimmune disease: Progress and problems
    • Furst DE. Stem cell transplantation for autoimmune disease: progress and problems. Curr Opin Rheumatol 2002;14:220-4.
    • (2002) Curr Opin Rheumatol , vol.14 , pp. 220-224
    • Furst, D.E.1
  • 35
    • 0034121227 scopus 로고    scopus 로고
    • Induction of immune tolerance to human type I collagen in patients with systemic sclerosis by oral administration of bovine type I collagen
    • McKown KM, Carbone LD, Bustillo J, et al. Induction of immune tolerance to human type I collagen in patients with systemic sclerosis by oral administration of bovine type I collagen. Arthritis Rheum 2000;43(5):1054-61.
    • (2000) Arthritis Rheum , vol.43 , Issue.5 , pp. 1054-1061
    • McKown, K.M.1    Carbone, L.D.2    Bustillo, J.3
  • 36
    • 7844237877 scopus 로고    scopus 로고
    • Interferon-gamma in the treatment of systemic sclerosis: A randomized controlled multicentre trial
    • Grassegger A, Schuler G, Hessenberger G, et al. Interferon-gamma in the treatment of systemic sclerosis: a randomized controlled multicentre trial. British J Derm 1998;139:639-48.
    • (1998) British J Derm , vol.139 , pp. 639-648
    • Grassegger, A.1    Schuler, G.2    Hessenberger, G.3
  • 37
    • 0033592753 scopus 로고    scopus 로고
    • A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis
    • Ziesche R, Hofbauer E, Wittman K, et al. A preliminary study of long-term treatment with interferon gamma-1b and low-dose prednisolone in patients with idiopathic pulmonary fibrosis. NEJM 1999;341:264-9.
    • (1999) NEJM , vol.341 , pp. 264-269
    • Ziesche, R.1    Hofbauer, E.2    Wittman, K.3
  • 38
    • 0029878115 scopus 로고    scopus 로고
    • A multicenter trial of recombinant human interferon gamma in patients with systemic sclerosis: Effects on cutaneous fibrosis and interleukin 2 receptor levels
    • Polisson RP, Gilkeson GS, Pyun EH, et al. A multicenter trial of recombinant human interferon gamma in patients with systemic sclerosis: effects on cutaneous fibrosis and interleukin 2 receptor levels. J Rheumatol 1996;23(4):654-8.
    • (1996) J Rheumatol , vol.23 , Issue.4 , pp. 654-658
    • Polisson, R.P.1    Gilkeson, G.S.2    Pyun, E.H.3
  • 39
    • 0032588623 scopus 로고    scopus 로고
    • Interferon-alpha does not improve outcome at one year in patients with diffuse cutaneous scleroderma: Results of a randomized, double-blind, placebo-controlled trial
    • Black CM, Silman AJ, Herrick AI, et al. Interferon-alpha does not improve outcome at one year in patients with diffuse cutaneous scleroderma: results of a randomized, double-blind, placebo-controlled trial. Arthritis Rheum 1999;42(2):299-305.
    • (1999) Arthritis Rheum , vol.42 , Issue.2 , pp. 299-305
    • Black, C.M.1    Silman, A.J.2    Herrick, A.I.3
  • 40
    • 0034612234 scopus 로고    scopus 로고
    • Recombinant human relaxin in the treatment of scleroderma
    • Seibold JR, Koran JH, Simons R, et al. Recombinant human relaxin in the treatment of scleroderma. Ann Intern Med 2000;132:871-9.
    • (2000) Ann Intern Med , vol.132 , pp. 871-879
    • Seibold, J.R.1    Koran, J.H.2    Simons, R.3
  • 41
    • 0035161153 scopus 로고    scopus 로고
    • Transforming growth factor-beta and connective tissue growth factor: Key cytokines in scleroderma pathogenesis
    • Denton CP, Abraham DJ. Transforming growth factor-beta and connective tissue growth factor: key cytokines in scleroderma pathogenesis. Curr Opin 2001;13(6):505-11.
    • (2001) Curr Opin , vol.13 , Issue.6 , pp. 505-511
    • Denton, C.P.1    Abraham, D.J.2
  • 42
    • 0036190919 scopus 로고    scopus 로고
    • Human antitransforming growth factor beta(2) monoclonal antibody-a new modulator of wound healing in trabeculectomy: A randomized placebo controlled clinical study
    • Siriwardena D, Khaw PT, King AJ, et al. Human antitransforming growth factor beta(2) monoclonal antibody-a new modulator of wound healing in trabeculectomy: a randomized placebo controlled clinical study. Ophthalmology 2002;109:427-31.
    • (2002) Ophthalmology , vol.109 , pp. 427-431
    • Siriwardena, D.1    Khaw, P.T.2    King, A.J.3
  • 43
    • 0018645674 scopus 로고
    • Measurement of clinical change in progressive systemic sclerosis: A 1 year double-blind placebo-controlled trial of N-acetylcysteine
    • Furst DE, Clements PJ, Harris R, et al. Measurement of clinical change in progressive systemic sclerosis: a 1 year double-blind placebo-controlled trial of N-acetylcysteine. Ann Rheum Dis 1979;38:356-61.
    • (1979) Ann Rheum Dis , vol.38 , pp. 356-361
    • Furst, D.E.1    Clements, P.J.2    Harris, R.3
  • 44
    • 0021209649 scopus 로고
    • Trial of platelet-inhibiting drug in scleroderma. Double-blind study with dipyridamole and aspirin
    • Beckett VL, Conn DL, Ruster V, et al. Trial of platelet-inhibiting drug in scleroderma. Double-blind study with dipyridamole and aspirin. Arthritis Rheum 1984;27:1137-43.
    • (1984) Arthritis Rheum , vol.27 , pp. 1137-1143
    • Beckett, V.L.1    Conn, D.L.2    Ruster, V.3
  • 45
    • 0021991505 scopus 로고
    • Double-blind, multi-center controlled trial comparing topical dimethyl sulfoxide and normal saline for treatment of hand ulcers in patients with systemic sclerosis
    • Williams HJ, Furst DE, Dahl SL, et al. Double-blind, multi-center controlled trial comparing topical dimethyl sulfoxide and normal saline for treatment of hand ulcers in patients with systemic sclerosis. Arthritis Rheum 1985;28:308-14.
    • (1985) Arthritis Rheum , vol.28 , pp. 308-314
    • Williams, H.J.1    Furst, D.E.2    Dahl, S.L.3
  • 46
    • 0021037758 scopus 로고
    • Cyclofenil treatment of scleroderma - A controlled study
    • Gibson T, Graham R. Cyclofenil treatment of scleroderma - a controlled study. Br J Rheumatol 1983;22:218-23.
    • (1983) Br J Rheumatol , vol.22 , pp. 218-223
    • Gibson, T.1    Graham, R.2
  • 47
    • 0019843558 scopus 로고
    • Cyclofenil versus placebo in progressive systemic sclerosis. A one-year double-blind crossover study of 27 patients
    • Blom-Bulow B, Berg K, Wilhelm RA, et al. Cyclofenil versus placebo in progressive systemic sclerosis. A one-year double-blind crossover study of 27 patients. Act Med Scand 1981;210:419-28.
    • (1981) Act Med Scand , vol.210 , pp. 419-428
    • Blom-Bulow, B.1    Berg, K.2    Wilhelm, R.A.3
  • 48
    • 0023686172 scopus 로고
    • Retrospective studies in scleroderma: Skin response to para-aminobenzoate therapy
    • Zarafonetis CJD, Dubach L, Skovronski JJ, et al. Retrospective studies in scleroderma: skin response to para-aminobenzoate therapy. Clin Exp Rheumatol 1988;6:261-8.
    • (1988) Clin Exp Rheumatol , vol.6 , pp. 261-268
    • Zarafonetis, C.J.D.1    Dubach, L.2    Skovronski, J.J.3
  • 49
    • 0028014279 scopus 로고
    • Comparison of aminobenzoate potassium and placebo in the treatment of scleroderma
    • Clegg DO, Reading JC, Mayes MD, et al. Comparison of aminobenzoate potassium and placebo in the treatment of scleroderma. J Rheumatol 1994;21:105-10.
    • (1994) J Rheumatol , vol.21 , pp. 105-110
    • Clegg, D.O.1    Reading, J.C.2    Mayes, M.D.3
  • 50
    • 0026096920 scopus 로고
    • A double-blind randomized controlled trial of ketotifen versus placebo in early diffuse scleroderma
    • Gruber BL, Kaufman LD. A double-blind randomized controlled trial of ketotifen versus placebo in early diffuse scleroderma. Arthritis Rheum 1991;34:362-5.
    • (1991) Arthritis Rheum , vol.34 , pp. 362-365
    • Gruber, B.L.1    Kaufman, L.D.2
  • 51
    • 0027403879 scopus 로고
    • Cyclosporine in systemic sclerosis: Results of a forty-eight-week open safety study in ten patients
    • Clements PJ, Lachenbruch PA, Sterz M, et al. Cyclosporine in systemic sclerosis: results of a forty-eight-week open safety study in ten patients. Arthritis Rheum 1993;36(1):75-83.
    • (1993) Arthritis Rheum , vol.36 , Issue.1 , pp. 75-83
    • Clements, P.J.1    Lachenbruch, P.A.2    Sterz, M.3


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