Synthesis of 1-boraadamantaneamine derivatives with selective astrocyte vs C6 glioma antiproliferative activity. A novel class of anti-hepatitis C agents with potential to bind CD81

Journal of Medicinal Chemistry

Volumn 46, Issue 14, 2003, Pages 2823-2833

  Wagner, Carl E ^a   Mohler, Michael L ^b   Kang, Gyong Suk ^b   Miller, Duane D ^b   Geisert, Eldon E ^c   Chang, Yu An ^d   Fleischer, Everly B ^a   Shea, Kenneth J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d RIC Biotech and Trading Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 BORAADAMANTANE PHENYLALANINE METHYL ESTER; 1 BORAADAMANTANEAMINE DERIVATIVE; 1 BORAADAMANTANEETHANOLAMINE; 2 [(ADAMANTANE 1 CARBONYL)AMINO] 3 PHENYLPROPIONIC ACID; AMANTADINE DERIVATIVE; ANTIVIRUS AGENT; CD81 ANTIGEN; MEMBRANE PROTEIN; TETRASPANIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN BINDING; ANTIVIRAL ACTIVITY; ARTICLE; ASTROCYTE; CELL LINEAGE; CONTROLLED STUDY; DRUG BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; GLIOMA; HEPATITIS C; HEPATITIS C VIRUS; NONHUMAN; PROTEIN BINDING; RAT; VIRUS ADSORPTION; VIRUS CELL INTERACTION; VIRUS TRANSMISSION;

ADAMANTANE; ANIMALS; ANTIGENS, CD; ANTINEOPLASTIC AGENTS; ANTIVIRAL AGENTS; ASTROCYTES; BORON COMPOUNDS; CRYSTALLOGRAPHY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; GLIOMA; HEPACIVIRUS; MEMBRANE PROTEINS; MODELS, MOLECULAR; PROTEIN BINDING; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0038460864     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020326d     Document Type: Article

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