Issues in the epidemiological analysis and interpretation of intermediate biomarkers

Cancer Epidemiology Biomarkers and Prevention

Volumn 12, Issue 6, 2003, Pages 491-496

  Rundle, Andrew ^a   Schwartz, Sharon ^a  

^a Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN; BIOLOGICAL MARKER; CARCINOGEN; GLUTATHIONE TRANSFERASE; POLYCYCLIC AROMATIC HYDROCARBON;

ARTICLE; CANCER DIAGNOSIS; CANCER RISK; CARCINOGEN DNA INTERACTION; DETOXIFICATION; DNA POLYMORPHISM; ENVIRONMENTAL FACTOR; EXPOSURE; GENOTYPE; LIVER CELL CARCINOMA; PRIORITY JOURNAL;

BIAS (EPIDEMIOLOGY); BIOLOGICAL MARKERS; CARCINOGENS, ENVIRONMENTAL; COHORT STUDIES; DATA INTERPRETATION, STATISTICAL; ENVIRONMENTAL EXPOSURE; EPIDEMIOLOGIC METHODS; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; MODELS, THEORETICAL; ODDS RATIO; POLYMORPHISM, GENETIC; RESEARCH DESIGN; SELECTION BIAS; STATISTICS;

EID: 0038458957     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Perera, F., and Weinstein, I. Molecular epidemiology and carcinogen-DNA adduct detection: new approaches to studies of human cancer causation. J. Chronic Dis., 35: 581-600, 1982.
2. Rothman, N., Stewart, W., and Schulte, P. Incorporating biomarkers into cancer epidemiology: a matrix of biomarker and study design categories. Cancer Epidemiol. Biomark. Prev., 4: 301-311, 1995.
3. Wild, C., and Pisani, P. Carcinogen-DNA and carcinogen-protein adducts in molecular epidemiology. IARC Sci. Publ., 142:143-158, 1997.
4. Chen, C., Yu, M., Liaw, Y., Wang, L., Chiamprasert, S., Matin, F., Hirvonen, A., Bell, D., and Santella, R. M. Chronic hepatitis B carriers with null genotypes of glutathione S-transferase M1 and T1 polymorphisms who are exposed to aflatoxin are at increased risk of hepatocellular carcinoma. Am. J. Hum. Genet., 59:128-134, 1996.
5. Vineis, P., Bartsch, H., Caporaso, N., Harrington, A., Kadlubar, F., Landi, M., Malaveille, C., Shields, P., Skipper, P., Talaska, G., et al. Genetically based N-acetyltransferase metabolic polymorphism and low-level environmental exposure to carcinogens. Nature (Lond.), 369:154-156, 1994.
6. Dickey, C., Santella, R., Hattis, D., Tang, D., Hsu, Y., Cooper, T., Young, T., and Perera, F. Variability in PAH-DNA adduct measurements in peripheral mononuclear cells: implications for quantitative cancer risk. Risk Anal., 17: 649-656, 1997.
7. Garte, S., Zocchetti, C., and Taioli, E. Gene-environment interactions in the application of biomarkers of cancer susceptibility in epidemiology. IARC Sci. Publ., 142: 251-264, 1997.
8. Tang, D., Rundle, A., Warburton, D., Santella, R., Tsai, W., Chiamprasert, S., Hsu, Y., and Perera, F. P. Associations between both genetic and environmental biomarkers and lung cancer: evidence of a greater risk of lung cancer in women smokers. Carcinogenesis (Lond.), 19:1949-1953, 1998.
9. Rundle, A., Tang. D., Hibshoosh, H., Estabrook, A., Schnabel, F., Cao, W., Grumet, S., and Perera, F. P. The relationship between genetic damage from polycyclic aromatic hydrocarbons in breast tissue and breast cancer. Carcinogenesis (Lond.), 21:1281-1289, 2000.
10. Tang, D., Phillips, D., Stampfer, M., Mooney, L., Hsu, Y., Cho, S., Tsai, W., Ma, J., Cole, K., She, M., and Perera, F. Association between carcinogen-DNA adducts in white blood cells and lung cancer risk in the physicians health study. Cancer Res., 61: 6708-6712, 2001.
11. Yu, M., Lien, J., Chiu, Y., Santella, R., Liaw, Y., and Chen, C. Effect of aflatoxin metabolism and DNA adduct formation on hepatocellular carcinoma among chronic hepatitis B carriers in Taiwan. J. Hepatol., 2: 320-330, 1997.
12. Hulka, B., and Margolin, B. Methodological issues in epidemiologic studies using biologic markers. Am. J. Epidemiol., 135: 200-209, 1992.
13. Sun, C., Wang, L., Chen, C., Lu, S., You, S., Wang, L., Wang, Q., Wu, D., and Santella, R. M. Genetic polymorphisms of glutathione S-transferases M1 and T1 associated with susceptibility to aflatoxin-related hepatocarcinogenesis among chronic hepatitis B carriers: a nested case-control study in Taiwan. Carcinogenesis (Lond.), 22:1289-1294, 2001.
14. Tang, D., Santella, R., Blackwood, A., Young, T., Mayer, J., Jaretzki, A., Grantham, S., Tsai, W., and Perera, F. A molecular epidemiologic case-control study of lung cancer. Cancer Epidemiol. Biomark. Prev., 4: 341-346, 1995.
15. Garcia-Closas, M., Rothman, N., and Lubin, J. Misclassification in case-control studies of gene-environment interactions: assessment of bias and sample size. Cancer Epidemiol Biomark. Prev., 8:1043-1050, 1999.
16. Rundle, A., Tang, D., Hibshoosh, H., Schnabel, F., Kelly, A., Levine, R., Zhou, J., Link, B., and Perera, F. Molecular epidemiologic studies of polycyclic aromatic hydrocarbon-DNA adducts and breast cancer. Environ. Mol. Mutagen., 39: 201-207, 2002.
17. Armstrong, B. Effect of measurement error on epidemiological studies of environmental and occupational exposures. Occup. Environ. Med., 55: 651-656, 1998.