Variability in PAH-DNA adduct measurements in peripheral mononuclear cells: Implications for quantitative cancer risk assessment

Risk Analysis

Volumn 17, Issue 5, 1997, Pages 649-656

  Dickey, Christopher ^a   Santella, Regina M ^a   Hattis, Dale ^b   Tang, Deliang ^a   Hsu, Yanzhi ^a   Cooper, Tom ^c   Young, Tie Lan ^a   Perera, Frederica P ^a  

^a Columbia University ^*  (United States)

^b CLARK UNIVERSITY   (United States)

^c NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

PAH DNA adducts; Risk assessment; Uncertainty; Variability

Indexed keywords

AROMATIC HYDROCARBONS; CELLS; DNA; HEALTH RISKS;

POLYCYCLIC AROMATIC HYDROCARBONS (PAH); QUANTITATIVE CANCER RISK ASSESSMENT;

RISK ASSESSMENT;

POLYCYCLIC AROMATIC HYDROCARBON;

CANCER RISK; CANCER SUSCEPTIBILITY; CIGARETTE SMOKING; DNA ADDUCT; DNA DAMAGE; FEMALE; GENOTOXICITY; HUMAN; HUMAN CELL; MALE; MONONUCLEAR CELL; REVIEW; RISK ASSESSMENT;

EID: 0031257475     PISSN: 02724332     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1539-6924.1997.tb00905.x     Document Type: Review

References (38)

1. EPA, Proposed Guidelines for Carcinogen Risk Assessment, Office of Research and Development, Report No. EPA/600/P-92/003C, Washington, D.C. (1996).
2. J. Griffith, R. C. Duncan, J. R. Goldsmith, and B. S. Hulka, "Biochemical and Biological Markers: Implications for Epidemiologic Studies," Arch. Environ. Health 44, 375-381 (1989).
3. F. P. Perera, J. Mayer, R. M. Santella, D. Brenner, W. Y. Tsai, P. Brandt-Rauf, and K. Hemminki, "DNA Adducts and Other Biological Markers in Risk Assessment for Environmental Carcinogens," Ann. Ist Super Sanita 27, 615-620 (1991).
4. N. E. Caporaso, "Molecular Epidemiology: A New Perspective for the Study of Toxic Exposures in Man. A Consideration of the Influence of Genetic Susceptibility Factors on Risk Different Lung Cancer Histologies," Med. Lay. 85, 68-77 (1994).
5. G. F. Combs, Jr., The Vitamins: Fundamental Aspects in Nutrition and Health (Academic Press, New York 1992).
6. F. P. Perera, "Validation of DNA Adducts as Biological Markers of Carcinogen Exposure and Effects," in M. L. Mendelsohn (eds.), Biomarkers and Occupational Health (Joseph Henry Press, Washington, D.C., 1995), pp. 105-108.
7. J. Lewtas, J. Mumford, R. B Everson, B. Hulka, T. Wilcosky, W. Kozumbo, C. Thompson, M. George, S. R. Dobiaa, X. Li et al., "Comparison of DNA Adducts from Exposure to Complex Mixtures in Various Human Tissues and Experimental Systems. Env. Health Perspect. 99, 89-97 (1993).
8. S. J. Stowers, and M. W. Anderson, "Formation and Persistence of Benzo[a]pyrene Metabolite-DNA Adducts," Env. Health Perspect. 62, 31-39 (1985).
9. M. C. Poirier, F. A. Beland, "DNA Adduct Measurements and Tumor Incidence During Chronic Carcinogen Exposure in Animal Models: Implications for DNA Adduct-Based Human Cancer Risk Assessment," Chem Res. Toxicol. 5, 749-755 (1992).
10. D. H. Phillips, B. Schoket, A. Hewer, E. Bailey, S. Kostic, and I. Vincze, "Influence of Cigarette Smoking on the Levels of DNA Adducts in Human Bronchial Epithelium and White Blood Cells," Int. J. Cancer 46, 569-675 (1990).
11. F. J. van Schooten, M. J. X Hillebrand, F. F. van Leeuwen, N. van Zandwijk, H. M. Jansen, L. den Engelse, and E. Kriek, "Polycyclic Aromatic Hydrocarbon-DNA Adducts in White Blood Cells from Lung Cancer Patients: No Correlation with Adduct Levels in Lung," Carcinogenesis 13, 987-993 (1992).
12. D. Tang, R. M. Santella, A. Blackwood, T. I. Young, J. Mayer, A. Jaretzki, S. Grantham, D. Carberry, K. M. Steinglass, W. Y. Tsai et al., "A Case-Control Molecular Epidemiologic Study of Lung Cancer," Cancer Epidemiol Biomed. Prevent. 4, 341-346 (1995)
13. B. J. K. Wiencke, K. T. Kelsey, A. Varkonyi, K. Semey, J. C. Wain, E. Mark, and D. C. Christiani, "Correlation of DNA Adducts in Blood Mononuclear Cells with Tobacco Carcinogen-Induced Damage in Human Lung," Cancer Res 55(21), 4910-4914 (1995).
14. F. P. Perera, K. Hemminki, E. Grzybowska, G. Motykiewicz, J. Michalska, R. M. Santella, T. L. Young, C. Dickey, P. BrandtRauf, I. DeVivo, et al, "Molecular and Genetic Damage from Environmental Pollution in Poland," Nature 360, 256-258 (1992).
15. L. A. Mooney, D. A. Bell. G. Lucier, R. Ottman, R. M. Santella, W. Y. Tsai, L. Covey, T. L. Young, and F. R. Perera, "Modulation of DNA Adducts in Heavy Smokers by Genetic Factors," Proc. AACR Annual Meeting 36, 711 (1995).
16. F. P. Perera, "Molecular Epidemiology in Cancer Prevention," Proc AACR 35, 656 (1994).
17. F. P. Perera, "Molecular Epidemiology: Insights into Cancer Susceptibility, Risk Assessment, and Prevention," JNCI 88, 496-509 (1996).
18. K. M. Thompson, D. E. Burmaster, and E. A. C. Crouch, "Monte Carlo Techniques for Quantitative Uncertainty Analysis in Public Health Risk Assessments," Risk Anal. 12(1), 53-63 (1992).
19. F. P. Perera, "Uncovering New Clues to Cancer Risk," Sci. Am. 40, 6 (May 1996).
20. E. Taioli, P. Kinney, A. Zhitkovich, H. Fulton, V. Voitkun, G. Cosma, K. Frenkel, P. Tomolo, S. Garte, and M. Costa, "Application of Reliability Models to Studies of Biomarker Validation," Env. Health Perspect. 102(3), 306-309 (1994).
21. F. Oesch, W. Aulmann, K. L. Platt, G. Doerjer, "Individual Differences in DNA Repair Capacities in Man," Arch. Toxicol. (Suppl.) 10, 172-179 (1987).
22. P. C. Hanawalt, "Heterogeneity of DNA Repair at the Gene Level," Mutat. Res. 247, 203-211 (1991).
23. H. Vainio, M. Waters, and H. Norppa, "Mutagenicity of Selected Organic Solvents," Scand. J. Work Environ. Health (Suppl.) 1, 75-82.
24. R. V. Cooney, A. A. Franke, J. H. Hankin, L. J. Custer, L. R. Wilkens, P. J. Harwood, and L. Le Marchand, "Seasonal Variations in Plasma Micronutrients and Antioxidants," Cancer Epidemiol. Biomed. Prevent. 4, 207-215 (1995).
25. F. Oesch, H. Schmassmann, E. Ohnhaus, U. Althaus, and J. Lorenz, "Monooxygenase, Epoxide Hydrolase, and Glutathione-s-Transferase Activities in Human Lung. Variation Between Groups of Bronchogenic Carcinoma and Non-Cancer Patients and Interindividual Differences," Carcinogenesis 1(10), 827-835 (1980).
26. W. C. Willet, "Micronutrients and Cancer Risk," Am. J. Clin. Nutr. 59, 1162s-1165s (1994).
27. I. G. C. Robertson, C. Guthenberg, B. Mannervik, and B. Jernstrom, "Differences in Stereoselectivity and Catalytic Efficiency of Three Human Glutathione Transferases in the Conjugation of Glutathione with 7B, 8 a-dihydroxy-9a, 10 a-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene," Cancer Res. 46, 2220-2224 (1986).
28. J. E. McWilliams, B. I. S. Sanderson, E. L. Harris, K. E. Richert-Boe, and W. D. Henner, "Glutathione S-transferase M1 (GSTM1) Deficiency and Lung Cancer Risk," Cancer Epidemiol. Biomed. Prevent. 4, 589-594 (1995).
29. R. A. Davis, "The Determination of Nicotine and Cotinine in Plasma," J. Chromat. Sci. 24, 134-341 (1986).
30. I. K. O'Neill, K. D. Brunnemann, B. Dodet, and D. Hoffmann, "Environmental Carcinogens: Methods of Analysis and Exposure Measurement," IARC Sci. Publ No. 81 9, 3-5 (1987).
31. F. P. Perera, K. Hemminki, T. I. Young, D. Brenner, G. Kelly, and R. M. Santella, "Detection of Polycyclic Aromatic Hydrocarbon-DNA Adducts in White Blood Cells of Foundry Workers," Cancer Res. 48, 2288-2291 (1988).
32. D. A. Bell, "Detection of DNA Sequenced Polymorphisms in Carcinogen Metabolism Genes by Polymerase Chain Reaction," Environ. Molec. Mutat. 18, 245-248 (1991).
33. C. P. Dickey, R. M. Santella, W. Blaner, D. Tang, D. Hattis, Y. Hsu, T. Cooper, A. van Bennekum, T. L. Young, and F. P. Perera, "Genetic and Nutritional Susceptibility Factors Related to PAH-DNA Adducts in Peripheral Mononuclear Cells from Smokers and Non-Smokers. In preparation.
34. N. M. Laird, and J. H. Ware, "Random-Effects Models for Longitudinal Data," Biometrics 38, 963-974 (1982).
35. M. Nelson, A. E. Black, J. A. Morris, and T. J. Cole, "Between and Within-Subject Variation in Nutrient Intake from Infancy to Old Age: Estimating the Number of Days Required to Rank Dietary Intakes with Desired Precision," Am J. Clin. Nutr. 50, 155-167 (1989).
36. R. H. Steirum, M. H. M. van Herwijnen, L. M. Maas, G. J. Hageman, and J. C. S. Kleinjans, "Measurement by 32P-Postlabeling of (+/-)Anti-benzo(a)pyrene-diolepoxide-N2-Deoxyguanosine Adduct Persistence in Unstimulated Human Peripheral Blood Lymphocytes," Mutat Res. 325, 31-37 (1994).
37. O. Holz, T. Krause, G. Scherer, U. Schmidt-Preub, and H. W. Rudiger, "32P-postlabelling Analysis of DNA Adducts in Monocytes of Smokers and Passive Smokers," Int. Arch. Occup. Environ. Health 62, 299-303 (1990).
38. B. Paigen, E. Ward, A. Reilly, L. Houten, H. L. Gurtoo, J. Minowada, K. Steenland, M. B. Havens, and P. Sartori, "Seasonal Variation of Aryl Hydrocarbon Hydroxylase Activity in Human Lymphocites," Cancer Res. 41, 2757-2761 (1981).