Acid infusion enhances duodenal mechanosensitivity in healthy subjects

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 285, Issue 2 48-2, 2003, Pages

  Simrén, Magnus ^a   Vos, Rita ^a   Janssens, Jozef ^a   Tack, Jan ^a,b  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Antroduodenal motility; Compliance; Duodenal tone; Perception

Indexed keywords

ACID; HYDROCHLORIC ACID;

ADULT; ARTICLE; BAROSTAT; CONTROLLED STUDY; DUODENUM; DUODENUM MOTILITY; DYSPEPSIA; FEMALE; GASTROINTESTINAL MOTILITY; HUMAN; HUMAN EXPERIMENT; MALE; MANOMETRY; NORMAL HUMAN; PERCEPTION; PERCEPTIVE THRESHOLD; PRIORITY JOURNAL; STOMACH ANTRUM; SYMPTOMATOLOGY;

EID: 0038442089     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00242.2002     Document Type: Article

References (34)

1. Andrioli A. Automated analysis of small bowel motility recordings. Leuven, Belgium: Katholieke Universiteit Leuven, 1998.
2. Björnsson ES and Abrahamsson H. Contractile patterns in patients with severe chronic dyspepsia. Am J Gastroenterol 94: 54-64, 1999.
3. Coffin B, Azpiroz F, Guarner F, and Malagelada JR. Selective gastric hypersensitivity and reflex hyporeactivity in functional dyspepsia. Gastroenterology 107: 1345-1351, 1994.
4. Coffin B, Chollet R, Flourie B, Lemann M, Franchisseur C, Rambaud JC, and Jian R. Intraluminal modulation of gastric sensitivity to distension: effects of hydrochloric acid and meal. Am J Physiol Gastrointest Liver Physiol 280: G904-G909, 2001.
5. Collen MJ and Loebenberg MJ. Basal gastric acid secretion in nonulcer dyspepsia with or without duodenitis. Dig Dis Sci 34: 246-250, 1989.
6. Feinle C, Meier O, Otto B, D'Amato M, and Fried M. Role of duodenal lipid and cholecystokinin A receptors in the pathophysiology of functional dyspepsia. Gut 48: 347-355, 2001.
7. George AA, Tsuchiyose M, and Dooley CP. Sensitivity of the gastric mucosa to acid and duodenal contents in patients with nonulcer dyspepsia. Gastroenterology 101: 3-6, 1991.
8. Greydanus MP, Vassallo M, Camilleri M, Nelson DK, Hanson RB, and Thomforde GM. Neurohormonal factors in functional dyspepsia: insights on pathophysiological mechanisms. Gastroenterology 100: 1311-1318, 1991.
9. Haug TT, Svebak S, Wilhelmsen I, Berstad A, and Ursin H. Psychological factors and somatic symptoms in functional dyspepsia. A comparison with duodenal ulcer and healthy controls. J Psychosom Res 38: 281-291, 1994.
10. Holtmann G, Goebell H, Jockenhoevel F, and Talley NJ. Altered vagal and intestinal mechanosensory function in chronic unexplained dyspepsia. Gut 42: 501-506, 1998.
11. Holtmann G, Talley NJ, and Goebell H. Association between H. pylori, duodenal mechanosensory thresholds, and small intestinal motility in chronic unexplained dyspepsia. Dig Dis Sci 41: 1285-1291, 1996.
12. Houghton LA, Kerrigan DD, and Read NW. Effect of intraduodenal infusion of acid on the antropyloroduodenal motor unit in human volunteers. J Gastrointest Motil 2: 202-208, 1990.
13. Hu WH, Martin CJ, and Talley NJ. Intraesophageal acid perfusion sensitizes the esophagus to mechanical distension: a barostat study. Am J Gastroenterol 95: 2189-2194, 2000.
14. Jones RH, Lydeard SE, Hobbs FD, Kenkre JE, Williams El, Jones SJ, Repper JA, Caldow JL, Dunwoodie WM, and Bottomley JM. Dyspepsia in England and Scotland. Gut 31: 401-405, 1990.
15. Lee KJ, Demarchi B, Vos R, Demedts I, Janssens J, and Tack J. Comparison of duodenal acid exposure in functional dyspepsia patients and healthy controls using 24-hour ambulatory duodenal pH monitoring (Abstract). Gastroenterology 122: A102, 2002.
16. Lewis TD, Collins SM, Fox JE, and Daniel EE. Initiation of duodenal acid-induced motor complexes. Gastroenterology 77: 1217-1224, 1979.
17. Lin HC, Doty JE, Reedy TJ, and Meyer JH. Inhibition of gastric emptying by acids depends on pH, titratable acidity, and length of intestine exposed to acid. Am J Physiol Gastrointest Liver Physiol 259: G1025-G1030, 1990.
18. Mearadji B, Straathof JW, Lamers CB, and Masclee AA. Effect of gastrin on proximal gastric motor function in humans. Neurogastroenterol Motil 11: 449-455, 1999.
19. Notivol R, Coffin B, Azpiroz F, Mearin F, Serra J, and Malagelada JR. Gastric tone determines the sensitivity of the stomach to distention. Gastroenterology 108: 330-336, 1995.
20. Parkman HP, Urbain JL, Knight LC, Brown KL, Trate DM, Miller MA, Maurer AH, and Fisher RS. Effect of gastric acid suppressants on human gastric motility. Gut 42: 243-250, 1998.
21. Rao SS, Lu C, and Schulze-Delrieu K. Duodenum as a immediate brake to gastric outflow: a videofluoroscopic and manometric assessment. Gastroenterology 110: 740-747, 1996.
22. Samsom M, Verhagen MA, Van Berge Henegouwen GP, and Smout AJ. Abnormal clearance of exogenous acid and increased acid sensitivity of the proximal duodenum in dyspeptic patients. Gastroenterology 116: 515-520, 1999.
23. Schwartz MP, Samsom M, Van Berge Henegouwen GP, and Smout AJ. Effect of inhibition of gastric acid secretion on antropyloroduodenal motor activity and duodenal acid hypersensitivity in functional dyspepsia. Aliment Pharmacol Ther 15: 1921-1928, 2001.
24. Stanghellini V, Ghidini C, Maccarini MR, Paparo GF, Corinaldesi R, and Barbara L. Fasting and postprandial gastrointestinal motility in ulcer and non-ulcer dyspepsia. Gut 33: 184-190, 1992.
25. Stanghellini V, Tosetti C, Paternico A, Barbara G, Morselli-Labate AM, Monetti N, Marengo M, and Corinaldesi R. Risk indicators of delayed gastric emptying of solids in patients with functional dyspepsia. Gastroenterology 110: 1036-1042, 1996.
26. Tack J, Caenepeel P, Fischler B, Piessevaux H, and Janssens J. Symptoms associated with hypersensitivity to gastric distention in functional dyspepsia. Gastroenterology 121: 526-535, 2001.
27. Tack J, Coulie B, Wilmer A, Andrioli A, and Janssens J. Influence of sumatriptan on gastric fundus tone and on the perception of gastric distension in man. Gut 46: 468-473, 2000.
28. Tack J, Piessevaux H, Coulie B, Caenepeel P, and Janssens J. Role of impaired gastric accommodation to a meal in functional dyspepsia. Gastroenterology 115: 1346-1352, 1998.
29. Talley NJ, Meineche-Schmidt V, Pare P, Duckworth M, Raisanen P, Pap A, Kordecki H, and Schmid V. Efficacy of omeprazole in functional dyspepsia: double-blind, randomized, placebo-controlled trials (the Bond and Opera studies). Aliment Pharmacol Ther 12: 1055-1065, 1998.
30. Talley NJ, Stanghellini V, Heading RC, Koch KL, Malagelada JR, and Tytgat GN. Functional gastroduodenal disorders. Gut 45, Suppl 2: 1137-1142, 1999.
31. Tucci A, Corinaldesi R, Stanghellini V, Tosetti C, Di Febo G, Paparo GF, Varoli O, Paganelli GM, Labate AM, Masci C, Zoccoli M, Nonelti N, and Barbara L. Helicobacter pylori infection and gastric function in patients with chronic idiopathic dyspepsia. Gastroenterology 103: 768-774, 1992.
32. Verkijk M, Gielkens HA, Lamers CB, and Masclee AA. Effect of gastrin on antroduodenal motility: role of intraluminal acidity. Am J Physiol Gastrointest Liver Physiol 275: G1209-G1216, 1998.
33. Wilmer A, Van Cutsem E, Andrioli A, Tack J, Coremans G, and Janssens J. Ambulatory gastrojejunal manometry in severe motility-like dyspepsia: lack of correlation between dysmotility, symptoms, and gastric emptying. Gut 42: 235-242, 1998.
34. Woodtli W and Owyang C. Duodenal pH governs interdigestive motility in humans. Am J Physiol Gastrointest Liver Physiol 268: G146-G152, 1995.