A convenient one-pot synthesis of 1,8-naphthyridones

Journal of Organic Chemistry

Volumn 68, Issue 11, 2003, Pages 4598-4599

  Springfield, Shawn A ^a   Marcantonio, Karen ^a   Ceglia, Scott ^a   Albaneze Walker, Jennifer ^a   Dormer, Peter G ^a   Nelson, Todd D ^a   Murry, Jerry A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ONE-POT SYNTHESIS;

BENZENE; CRYSTALLIZATION; IMPURITIES; SUBSTITUTION REACTIONS;

SYNTHESIS (CHEMICAL);

1,8 NAPHTHYRIDIN 4 ONE DERIVATIVE; 1,8 NAPHTHYRIDINE DERIVATIVE; ACETONITRILE DERIVATIVE; ACRYLIC ACID DERIVATIVE; ANILINE DERIVATIVE; BENZENE DERIVATIVE; TRICARBOXYLIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CRYSTALLIZATION; POLYMERIZATION; REACTION TIME; SYNTHESIS;

EID: 0038441368     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo034321f     Document Type: Article

References (11)

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10. Chemistry involving the use of 3,3-dimethylaminoacrylate to form a 2-benzoylacrylic carboxylate was demonstrated in the following: Grohe, K. U.S. Patent 2 699 992, 1987. Bose, P.; Kumar, N.; Kiyoto, T. W.O. Patent 01 66512 A1, 2001. Neither utilized this chemistry for preparing 1,8-naphthyridin-4-ones.
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