Design, synthesis and pharmacological evaluation of new anticancer fused pentacycles

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 18, Issue 2, 2003, Pages 95-99

  Chackal, Sarah ^a   Houssin, Raymond ^a   Pommery, Nicole ^a   Henichart, Jean Pierre ^a  

^a Faculté des Sciences Pharmaceutiques et Biologiques Université de Lille   (France)

Author keywords

Ascididemin; Benzopyridoacridine; Cytotoxicity; DHDMC; Prostatic cell lines

Indexed keywords

10 (2 AMINOETHOXY) 4,5 DIMETHOXY 3 [2 (4 METHYL)PIPERAZIN 1 YLACETYL] 2,3,12,13 TETRAHYDRO 1H BENZO[C]PYRIDO[2,3,4 KL]ACRIDINE; 10 (3 AMINOETHOXY) 4,5 DIMETHOXY 2,3,12,13 TETRAHYDRO 1H BENZO[C]PYRIDO[2,3,4 KL]ACRIDINE; 10 (3 AMINOPROPOXY) 4,5 DIMETHOXY 2,3,12,13 TETRAHYDRO 1H BENZO[C]PYRIDO[2,3,4 KL]ACRIDINE; 10 (3 AMINOPROPOXY) 4,5 DIMETHOXY 3 [2 (4 METHYL)PIPERAZIN 1 YLACETYL] 2,3,12,13 TETRAHYDRO 1H BENZO[C]PYRIDO[2,3,4 KL]ACRIDINE; 10 HYDROXY 4,5 DIMETHOXY 3 [2 (4 METHYL) PIPERAZIN 1 YLACETYL] 2,3,12,13 TETRAHYDRO 1H BENZO[C]PYRIDO[2,3,4 KL]ACRIDINE; 3 ACETYL 10 (2 AMINOETHOXY) 4,5 DIMETHOXY 2,3,12,13 TETRAHYDRO 1H BENZO[C]PYRIDO[2,3,4 KL]ACRIDINE; 3 ACETYL 10 (2 AMINOPROPOXY) 4,5 DIMETHOXY 2,3,12,13 TETRAHYDRO 1H BENZO[C]PYRIDO[2,3,4 KL]ACRIDINE; 3 ACETYL 10 HYDROXY 4,5 DIMETHOXY 2,3,12,13 TETRAHYDRO 1H BENZO[C]PYRIDO[2,3,4 KL]ACRIDINE; 4,5 DIMETHOXY 10 [3 (4 METHYL)PIPERAZIN 1 YLPROPOXY] 2,3,12,13 TETRAHYDRO 1H BENZO[C]PYRIDO[2,3,4 KL]ACRIDINE; 5,6 DIHYDRO 8 DESMETHYLCORALYNE; ANTINEOPLASTIC AGENT; ASCIDIDEMIN; BENZO[C]PYRIDO[2,3,4 KL]ACRIDINE DERIVATIVE; CAMPTOTHECIN DERIVATIVE; CYTOTOXIC AGENT; PROTOBERBERINE DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CHROMATOPHORE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; PROSTATE CANCER;

ACRIDINES; ANTINEOPLASTIC AGENTS; CELL DIVISION; CELL SURVIVAL; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INHIBITORY CONCENTRATION 50; MALE; MOLECULAR STRUCTURE; PROSTATIC NEOPLASMS; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0038440623     PISSN: 14756366     EISSN: None     Source Type: Journal    
DOI: 10.1080/1475636031000093525     Document Type: Article

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