Synthesis, pharmacological study and modeling of 7-methoxyindazole and related substituted indazoles as neuronal nitric oxide synthase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 18, Issue 2, 2003, Pages 195-199

  Collot, Valérie ^a   Sopkova De Oliveira Santos, Jana ^a   Schumann Bard, Pascale ^a   Colloc'h, Nathalie ^a   Mackenzie, Eric T ^a   Rault, Sylvain ^a  

^a UNIVERSITÉ DE CAEN   (France)

Author keywords

7 Methoxyindazole; Inhibitors; Molecular modelling; Neuronal nitric oxide synthase; Structure activity relationships

Indexed keywords

7 BENZYLOXYINDAZOLE; 7 BUTOXYINDAZOLE; 7 ETHOXYINDAZOLE; 7 HYDROXYINDAZOLE; 7 METHOXYINDAZOLE; 7 PROPOXYINDAZOLE; INDAZOLE DERIVATIVE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME ASSAY; IN VITRO STUDY; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; RAT; STRUCTURE ACTIVITY RELATION;

ANIMALS; CEREBELLUM; ENZYME INHIBITORS; INDAZOLES; MODELS, CHEMICAL; MOLECULAR STRUCTURE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA;

EID: 0038440567     PISSN: 14756366     EISSN: None     Source Type: Journal    
DOI: 10.1080/1475636032000069864     Document Type: Article

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