메뉴 건너뛰기




Volumn 46, Issue SUPPL. 1, 2003, Pages

Rationale and options for combination therapy in the treatment of Type 2 diabetes

Author keywords

Combination therapy; D phenylalanine derivative; Insulin secretion enhancer; Nateglinide; Postprandial glucose; Type 2 diabetes

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ACARBOSE; ALPHA GLUCOSIDASE INHIBITOR; AMINO ACID DERIVATIVE; ANTIDIABETIC AGENT; BENZOIC ACID DERIVATIVE; BIGUANIDE DERIVATIVE; GLIBENCLAMIDE; INSULIN; METFORMIN; MIGLITOL; NATEGLINIDE; ORAL ANTIDIABETIC AGENT; PIOGLITAZONE; REPAGLINIDE; ROSIGLITAZONE; SULFONYLUREA DERIVATIVE; TROGLITAZONE;

EID: 0038415951     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-002-0936-0     Document Type: Article
Times cited : (69)

References (43)
  • 1
    • 0030831056 scopus 로고    scopus 로고
    • Nonfasting plasma glucose is a better marker of diabetic control than fasting plasma glucose in Type 2 diabetes
    • Avignon A, Radauceanu A, Monnier L (1997) Nonfasting plasma glucose is a better marker of diabetic control than fasting plasma glucose in Type 2 diabetes. Diabetes Care 20:1822-1826
    • (1997) Diabetes Care , vol.20 , pp. 1822-1826
    • Avignon, A.1    Radauceanu, A.2    Monnier, L.3
  • 2
    • 0023916553 scopus 로고
    • Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus
    • Polonsky KS, Given BD, Hirsch LJ et al. (1988) Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus. N Engl J Med 318:231-239
    • (1988) N Engl J Med , vol.318 , pp. 231-239
    • Polonsky, K.S.1    Given, B.D.2    Hirsch, L.J.3
  • 3
    • 0034851942 scopus 로고    scopus 로고
    • Insulin resistance and β-cell dysfunction as therapeutic targets in type 2 diabetes
    • Evans AJ, Krenz AJ (2001) Insulin resistance and β-cell dysfunction as therapeutic targets in type 2 diabetes. Diabetes Obes Metab 3:219-229
    • (2001) Diabetes Obes Metab , vol.3 , pp. 219-229
    • Evans, A.J.1    Krenz, A.J.2
  • 4
    • 0033853912 scopus 로고    scopus 로고
    • Is postprandial glucose a neglected cardiovascular risk factor in Type 2 diabetes?
    • Monnier L (2000) Is postprandial glucose a neglected cardiovascular risk factor in Type 2 diabetes? Eur J Clin Invest 30 [Suppl 2]:3-11
    • (2000) Eur J Clin Invest , vol.30 , Issue.SUPPL. 2 , pp. 3-11
    • Monnier, L.1
  • 5
    • 0024216182 scopus 로고
    • Physiological importance of deficiency in early prandial insulin secretion in non-insulin-dependent diabetes
    • Bruce DG, Chisholm DJ, Storlien LH, Kraegen EW (1988) Physiological importance of deficiency in early prandial insulin secretion in non-insulin-dependent diabetes. Diabetes 37:736-744
    • (1988) Diabetes , vol.37 , pp. 736-744
    • Bruce, D.G.1    Chisholm, D.J.2    Storlien, L.H.3    Kraegen, E.W.4
  • 6
    • 0029094533 scopus 로고
    • 1c) to the risk of development and progression of retinopathy in the Diabetes Control and Complications Trial
    • 1c) to the risk of development and progression of retinopathy in the Diabetes Control and Complications Trial. Diabetes 44:968-983
    • (1995) Diabetes , vol.44 , pp. 968-983
  • 7
    • 0032511580 scopus 로고    scopus 로고
    • Tight blood pressure control and risk of macrovascular and microvascular complications in Type 2 diabetes. (UKPDS 38)
    • UK Prospective Diabetes Study (UKPDS) Group
    • UKPDS 38 (1998) Tight blood pressure control and risk of macrovascular and microvascular complications in Type 2 diabetes. (UKPDS 38). UK Prospective Diabetes Study (UKPDS) Group. BMJ 317:703-713
    • (1998) BMJ , vol.317 , pp. 703-713
  • 8
    • 0033592101 scopus 로고    scopus 로고
    • Glucose tolerance and mortality: Comparison of WHO and American Diabetes Association diagnostic criteria
    • The DECODE study group on behalf of the European Diabetes Epidemiology Group (1999) Glucose tolerance and mortality: comparison of WHO and American Diabetes Association diagnostic criteria. Lancet 354:617-621
    • (1999) Lancet , vol.354 , pp. 617-621
  • 9
    • 0029147687 scopus 로고
    • Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin dependent diabetes mellitus: A randomized prospective 6-year study
    • Okhubo Y, Kishikawa H, Araki E et al. (1995) Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin dependent diabetes mellitus: a randomized prospective 6-year study. Diabetes Res Clin Pract 28:103-117
    • (1995) Diabetes Res Clin Pract , vol.28 , pp. 103-117
    • Okhubo, Y.1    Kishikawa, H.2    Araki, E.3
  • 10
    • 0034005755 scopus 로고    scopus 로고
    • The postprandial state and cardiovascular disease: Relevance to diabetes mellitus
    • Ceriello A (2000) The postprandial state and cardiovascular disease: relevance to diabetes mellitus. Diabetes Metab Res Rev 16:125-132
    • (2000) Diabetes Metab Res Rev , vol.16 , pp. 125-132
    • Ceriello, A.1
  • 12
    • 0029957413 scopus 로고    scopus 로고
    • Risk factors for myocardial infarction and death in newly detected NIDDM: The Diabetes Intervention Study, 11-year follow-up
    • Hanefeld M, Fischer S, Julius U et al. The DIS Group (1996) Risk factors for myocardial infarction and death in newly detected NIDDM: the Diabetes Intervention Study, 11-year follow-up. Diabetologia 39:1577-1583
    • (1996) Diabetologia , vol.39 , pp. 1577-1583
    • Hanefeld, M.1    Fischer, S.2    Julius, U.3
  • 13
    • 0035814611 scopus 로고    scopus 로고
    • Glycated haemoglobin, diabetes and mortality in men in Norfolk cohort of European prospective investigation of cancer and nutrition (EPIC-Norfolk)
    • Khaw K-T, Wareham N, Luben R et al. (2001) Glycated haemoglobin, diabetes and mortality in men in Norfolk cohort of European prospective investigation of cancer and nutrition (EPIC-Norfolk). BMJ 322:1-6
    • (2001) BMJ , vol.322 , pp. 1-6
    • Khaw, K.-T.1    Wareham, N.2    Luben, R.3
  • 14
    • 0032983666 scopus 로고    scopus 로고
    • Glycemic control with diet, sulphonylurea, metformin, or insulin in patients with Type 2 diabetes mellitus: Progressive requirement for multiple therapies (UKPDS 49)
    • UK Prospective Diabetes Study (UKPDS) Group
    • Turner RC, Cull CA, Frighi V, Holman RR (1999) Glycemic control with diet, sulphonylurea, metformin, or insulin in patients with Type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group. JAMA 281: 2005-2012
    • (1999) JAMA , vol.281 , pp. 2005-2012
    • Turner, R.C.1    Cull, C.A.2    Frighi, V.3    Holman, R.R.4
  • 15
    • 0031964322 scopus 로고    scopus 로고
    • A randomized trial of efficacy of early addition of metformin in sulphonylurea-treated Type 2 diabetes
    • UK Prospective Diabetes Study (UKPDS) Group
    • UKPDS 28 (1998) A randomized trial of efficacy of early addition of metformin in sulphonylurea-treated Type 2 diabetes. UK Prospective Diabetes Study (UKPDS) Group. Diabetes Care 21:87-92
    • (1998) Diabetes Care , vol.21 , pp. 87-92
  • 16
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with Type 2 diabetes
    • UK Prospective Diabetes Study (UKPDS) Group
    • UKPDS 33 (1998) Intensive blood glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with Type 2 diabetes. UK Prospective Diabetes Study (UKPDS) Group. Lancet 352:837-853
    • (1998) Lancet , vol.352 , pp. 837-853
  • 17
    • 0032511566 scopus 로고    scopus 로고
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with Type 2 diabetes (UKPDS 34)
    • UK Prospective Diabetes Study (UKPDS) Group
    • UKPDS 34 (1998) Effect of intensive blood-glucose control with metformin on complications in overweight patients with Type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet 352:354-365
    • (1998) Lancet , vol.352 , pp. 354-365
  • 18
    • 0034678764 scopus 로고    scopus 로고
    • Combining sulphonylureas and other oral agents
    • Riddle M (2000) Combining sulphonylureas and other oral agents. Am J Med 108:15S-22S
    • (2000) Am J Med , vol.108
    • Riddle, M.1
  • 19
    • 0037116638 scopus 로고    scopus 로고
    • Oral antihyperglycemic therapy for type 2 diabetes. Scientific review
    • Inzucchi SE (2002) Oral antihyperglycemic therapy for type 2 diabetes. Scientific review. JAMA 287:360-372
    • (2002) JAMA , vol.287 , pp. 360-372
    • Inzucchi, S.E.1
  • 20
    • 0027935577 scopus 로고
    • Therapeutic comparison of metformin and sulfonylurea, alone and in various combinations. A double-blind controlled study
    • Hermann LS, Schersten B, Bitzen PO et al. (1994) Therapeutic comparison of metformin and sulfonylurea, alone and in various combinations. A double-blind controlled study. Diabetes Care: 17:1100-1109
    • (1994) Diabetes Care , vol.17 , pp. 1100-1109
    • Hermann, L.S.1    Schersten, B.2    Bitzen, P.O.3
  • 21
    • 0029064970 scopus 로고
    • Multicentre, placebo controlled trial comparing acarbose (BAY g 5421) with placebo, tolbutamide and tolbutamide plus acarbose in non-insulin dependent diabetes mellitus
    • Coniff RF, Shapiro JA, Seaton TB, Bray GA (1995) Multicentre, placebo controlled trial comparing acarbose (BAY g 5421) with placebo, tolbutamide and tolbutamide plus acarbose in non-insulin dependent diabetes mellitus. Am J Med 98:443-451
    • (1995) Am J Med , vol.98 , pp. 443-451
    • Coniff, R.F.1    Shapiro, J.A.2    Seaton, T.B.3    Bray, G.A.4
  • 22
  • 24
    • 0343724362 scopus 로고    scopus 로고
    • Comparison of bedtime insulin regimens in patients with Type 2 diabetes mellitus. A randomised, controlled trial
    • Yki-Järvinen H, Ryysy L, Nikkila K, Tulokas T, Vanamo R, Heikkila M (1999) Comparison of bedtime insulin regimens in patients with Type 2 diabetes mellitus. A randomised, controlled trial. Ann Intern Med 130:389-396
    • (1999) Ann Intern Med , vol.130 , pp. 389-396
    • Yki-Järvinen, H.1    Ryysy, L.2    Nikkila, K.3    Tulokas, T.4    Vanamo, R.5    Heikkila, M.6
  • 25
    • 0031755644 scopus 로고    scopus 로고
    • Advantages of alpha-glucosidase inhibition as monotherapy in elderly Type 2 diabetic patients
    • Johnston PS, Lebovitz HE, Coniff RF et al. (1998) Advantages of alpha-glucosidase inhibition as monotherapy in elderly Type 2 diabetic patients. J Clin Endocrinol Metab 83:1515-1522
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1515-1522
    • Johnston, P.S.1    Lebovitz, H.E.2    Coniff, R.F.3
  • 26
    • 0038099356 scopus 로고
    • Metformin: A review of its pharmacological properties and therapeutic use
    • Hermann LS (1979) Metformin: a review of its pharmacological properties and therapeutic use. Diabetes Metab 5233-5245
    • (1979) Diabetes Metab , pp. 5233-5245
    • Hermann, L.S.1
  • 28
    • 0035146515 scopus 로고    scopus 로고
    • Once- and twice-daily dosing with rosiglitazone improves glycemia control in patients with type 2 diabetes
    • Phillips LS, Grunberger G, Miller E, Patwardhan R, Rappaport EB, Salzman A, The Rosiglitazone Clinical Trials Study Group (2001) Once- and twice-daily dosing with rosiglitazone improves glycemia control in patients with type 2 diabetes. Diabetes Care 24:308-315
    • (2001) Diabetes Care , vol.24 , pp. 308-315
    • Phillips, L.S.1    Grunberger, G.2    Miller, E.3    Patwardhan, R.4    Rappaport, E.B.5    Salzman, A.6
  • 29
    • 0034607438 scopus 로고    scopus 로고
    • Effect of metformin and rosiglitazone combination therapy in patients with Type 2 diabetes mellitus: A randomised controlled trial
    • Fonseca V, Rosenstock J, Patwardhan R, Salzman A (2000) Effect of metformin and rosiglitazone combination therapy in patients with Type 2 diabetes mellitus: a randomised controlled trial. JAMA 283:1695-1702
    • (2000) JAMA , vol.283 , pp. 1695-1702
    • Fonseca, V.1    Rosenstock, J.2    Patwardhan, R.3    Salzman, A.4
  • 30
    • 0034531195 scopus 로고    scopus 로고
    • Pioglitazone hydrochloride in combination with metformin in the treatment of type 2 diabetes mellitus: A randomized, placebo-controlled study
    • The Pioglitazone 027 Study Group
    • Einhorn D, Rendell M, Rosenzweig J, Egan JW, Mathisen AL, Schneider RL (2000) Pioglitazone hydrochloride in combination with metformin in the treatment of type 2 diabetes mellitus: a randomized, placebo-controlled study, The Pioglitazone 027 Study Group. Clin Ther 22:1395-1409
    • (2000) Clin Ther , vol.22 , pp. 1395-1409
    • Einhorn, D.1    Rendell, M.2    Rosenzweig, J.3    Egan, J.W.4    Mathisen, A.L.5    Schneider, R.L.6
  • 31
    • 0034933056 scopus 로고    scopus 로고
    • Pioglitazone hydrochloride in combination with sulfonylurea therapy improves glycemic control in patients with type 2 diabetes mellitus: A randomized, placebo-controlled trial
    • Kipnes MS, Krosnick A, Rendell MS, Egan JW, Mathisen AL, Schneider RL (2001) Pioglitazone hydrochloride in combination with sulfonylurea therapy improves glycemic control in patients with type 2 diabetes mellitus: a randomized, placebo-controlled trial. Am J Med 111:10-17
    • (2001) Am J Med , vol.111 , pp. 10-17
    • Kipnes, M.S.1    Krosnick, A.2    Rendell, M.S.3    Egan, J.W.4    Mathisen, A.L.5    Schneider, R.L.6
  • 32
    • 0030065192 scopus 로고    scopus 로고
    • Efficacy of insulin and sulphonylurea combination therapy in Type 2 diabetes. A meta-analysis of the randomised placebo-controlled trials
    • Johnson JL, Wolf SL, Kabadi UM (1996) Efficacy of insulin and sulphonylurea combination therapy in Type 2 diabetes. A meta-analysis of the randomised placebo-controlled trials. Arch Intern Med 156:259-264
    • (1996) Arch Intern Med , vol.156 , pp. 259-264
    • Johnson, J.L.1    Wolf, S.L.2    Kabadi, U.M.3
  • 33
    • 0034098771 scopus 로고    scopus 로고
    • Rosiglitazone short-term monotherapy lowers fasting and postprandial glucose in patients with Type 2 diabetes
    • Raskin P, Rappaport EB, Cole ST, Yan Y, Patwardhan R, Freed MI (2000) Rosiglitazone short-term monotherapy lowers fasting and postprandial glucose in patients with Type 2 diabetes. Diabetologia 43:278-284
    • (2000) Diabetologia , vol.43 , pp. 278-284
    • Raskin, P.1    Rappaport, E.B.2    Cole, S.T.3    Yan, Y.4    Patwardhan, R.5    Freed, M.I.6
  • 34
    • 0033985728 scopus 로고    scopus 로고
    • Rapid and short-acting mealtime insulin secretion with nateglinide controls both prandial and mean glycemia
    • Hanefeld M, Bouter KP, Dickinson S, Guitard C (2000) Rapid and short-acting mealtime insulin secretion with nateglinide controls both prandial and mean glycemia. Diabetes Care 23:202-207
    • (2000) Diabetes Care , vol.23 , pp. 202-207
    • Hanefeld, M.1    Bouter, K.P.2    Dickinson, S.3    Guitard, C.4
  • 35
    • 0345434811 scopus 로고    scopus 로고
    • Effect of repaglinide addition to metformin monotherapy on glycemic control in patients with Type 2 diabetes
    • Moses R, Slobodniuk R, Boyages S et al. (1999) Effect of repaglinide addition to metformin monotherapy on glycemic control in patients with Type 2 diabetes. Diabetes Care 22:119-124
    • (1999) Diabetes Care , vol.22 , pp. 119-124
    • Moses, R.1    Slobodniuk, R.2    Boyages, S.3
  • 36
    • 0033754777 scopus 로고    scopus 로고
    • Nateglinide alone and in combination with metformin improves glycemic control by reducing mealtime glucose spikes in Type 2 diabetes
    • Horton E, Clinkingbeard C, Gatlin M, Foley J, Mallows S, Shen S (2000) Nateglinide alone and in combination with metformin improves glycemic control by reducing mealtime glucose spikes in Type 2 diabetes. Diabetes Care 23:1660-1665
    • (2000) Diabetes Care , vol.23 , pp. 1660-1665
    • Horton, E.1    Clinkingbeard, C.2    Gatlin, M.3    Foley, J.4    Mallows, S.5    Shen, S.6
  • 37
    • 0036265936 scopus 로고    scopus 로고
    • Nateglinide improves glycaemic control when added to metformin monotherapy: Results of a randomised trial with type 2 diabetes patients
    • Marre M, Van Gaal L, Usadel K-H, Ball M, Whatmough I, Guitard C (2002) Nateglinide improves glycaemic control when added to metformin monotherapy: results of a randomised trial with type 2 diabetes patients. Diabetes Obes Metab 4:177-186
    • (2002) Diabetes Obes Metab , vol.4 , pp. 177-186
    • Marre, M.1    Van Gaal, L.2    Usadel, K.-H.3    Ball, M.4    Whatmough, I.5    Guitard, C.6
  • 38
    • 0000414191 scopus 로고    scopus 로고
    • Nateglinide improves glycemic control alone and in combination with troglitazone in patients with Type 2 diabetes
    • Rosenstock J, Gatlin M, Mallows S, Bush C (2000) Nateglinide improves glycemic control alone and in combination with troglitazone in patients with Type 2 diabetes. Diabetes 49 [Suppl 1]:498
    • (2000) Diabetes , vol.49 , Issue.SUPPL. 1 , pp. 498
    • Rosenstock, J.1    Gatlin, M.2    Mallows, S.3    Bush, C.4
  • 39
    • 0033927081 scopus 로고    scopus 로고
    • Repaglinide/troglitazone combination therapy: Improved glycemic control in type 2 diabetes
    • Raskin P, Jovanovic L, Berger S et al. (2000) Repaglinide/troglitazone combination therapy: improved glycemic control in type 2 diabetes. Diabetes Care 23:979-983
    • (2000) Diabetes Care , vol.23 , pp. 979-983
    • Raskin, P.1    Jovanovic, L.2    Berger, S.3
  • 40
    • 0034898982 scopus 로고    scopus 로고
    • Repaglinide improves blood glucose control in sulphonylurea-naïve type 2 diabetes
    • Van Gaal L, Van Acker K, De Leeuw IH (2001) Repaglinide improves blood glucose control in sulphonylurea-naïve type 2 diabetes. Diabetes Res Clin Pract 53:141-148
    • (2001) Diabetes Res Clin Pract , vol.53 , pp. 141-148
    • Van Gaal, L.1    Van Acker, K.2    De Leeuw, I.H.3
  • 41
    • 0035490421 scopus 로고    scopus 로고
    • Effect of repaglinide addition to NPH insulin monotherapy on glycemic control in patients with type 2 diabetes
    • De Luis DA, Aller R, Cuellar L et al. (2001) Effect of repaglinide addition to NPH insulin monotherapy on glycemic control in patients with type 2 diabetes. Diabetes Care 24:1844-1845
    • (2001) Diabetes Care , vol.24 , pp. 1844-1845
    • De Luis, D.A.1    Aller, R.2    Cuellar, L.3
  • 42
    • 0024586640 scopus 로고
    • Drug-induced hypoglycaemia: A review of 1418 cases
    • Seltzer HS (1989) Drug-induced hypoglycaemia: a review of 1418 cases. Endocr Metab Clin North Am 18:163-183
    • (1989) Endocr Metab Clin North Am , vol.18 , pp. 163-183
    • Seltzer, H.S.1
  • 43
    • 0035132993 scopus 로고    scopus 로고
    • Mealtime glucose regulation with nateglinide in healthy volunteers: Comparison with repaglinide and placebo
    • Kalbag JB, Walter YH, Nedelman JR, McLeod JF (2001) Mealtime glucose regulation with nateglinide in healthy volunteers: comparison with repaglinide and placebo. Diabetes Care 24:73-77
    • (2001) Diabetes Care , vol.24 , pp. 73-77
    • Kalbag, J.B.1    Walter, Y.H.2    Nedelman, J.R.3    McLeod, J.F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.