Safety assessment for genetically modified sweet pepper and tomato

Toxicology

Volumn 188, Issue 2-3, 2003, Pages 297-307

  Chen, Zhang Liang ^a   Gu, Hongya ^a   Li, Yi ^a   Su, Yilan ^b   Wu, Ping ^b   Jiang, Zhicheng ^b   Ming, Xiaotian ^a   Tian, Jinhua ^a   Pan, Naisui ^a   Qu, Li Jia ^a  

^a PEKING UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

CMV cp; Feeding test; GM plants; Safety assessment

Indexed keywords

AMES TEST; ANIMAL EXPERIMENT; ARTICLE; BLOOD ANALYSIS; BODY GROWTH; CUCUMBER MOSAIC VIRUS; DNA MODIFICATION; FEMALE; FOOD INTAKE; FOOD SAFETY; GENE CONSTRUCT; GENOTOXICITY; HEMATOLOGY; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; MALE; MICRONUCLEUS TEST; MOLECULAR CLONING; NONHUMAN; ORGAN WEIGHT; PRIORITY JOURNAL; PROMOTER REGION; RAT; RISK ASSESSMENT; SWEET PEPPER; TOMATO; VIRUS GENE; VIRUS RESISTANCE; WEIGHT GAIN;

ANIMALIA; CAPSICUM ANNUUM VAR. ANNUUM; CUCUMBER MOSAIC VIRUS; CUCUMIS SATIVUS; LYCOPERSICON ESCULENTUM;

EID: 0038398991     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(03)00111-2     Document Type: Article

References (26)

1. Abel P.P., Nelson R.S., De B., Hoffmann N., Roger S.G., Fraley R.T., Beachy R.N. Delay of disease development in transgenic plants that express the tobacco mosaic virus coat protein gene. Science. 232:1986;738-743.
2. Chen Z.L., Gu H.Y. Plant biotechnology in China. Science. 262:1993;377-378.
3. Dunnett C.W. A multiple comparison procedure for comparing several treatments with a control. J. Am. Stat. Assoc. 50:1955;1089-1121.
4. Ewen S.W., Pusztai A. Effect of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine. Lancet. 354:(1):1999;353-354.
5. Fitchen J., Beachy R.N. Genetically engineered protection against viruses in transgenic plants. Annu. Rev. Microbiol. 47:1993;739-763.
6. Hammond B.G., Vicini J.L., Hartnell G.F., Naylor M.W., Knight C.D., Robinson E.H., Fuchs R.L., Padgette S.R. The feeding value of soybeans fed to rats, chickens, catfish and dairy cattle is not altered by genetic incorporation of glyphosate tolerance. J. Nutr. 126:1996;717-727.
7. Harrison L.A., Bailey M.R., Burnette B., Naylor M.W., Nida D.L., Nickson T., Ream J., Taylor M., Padgette S.R. The expressed protein in glyphosate-tolerant soybeans, 5-enolpyruvyl-shikimate-3-phosphate synthase from Agrobacterium sp. Strain CP4, is rapidly digested in vitro and is not toxic to acutely gavaged mice. J. Nutr. 126:1996;728-740.
8. Hu T.H., Wu L., Liu W., Mi J.J., Pan N.S., Chen Z.L. cDNA cloning of gene encoding coat protein of cucumber mosaic virus infecting tobacco in China. Chin. Sci. Bull. 35:1990;1209-1214.
9. James, C., 1998. Global review of commercialized transgenic crops: ISAAA Briefs No.8. ISAAA, Ithaca, NY.
10. James, C., 1999. Global review of commercialized transgenic crops: ISAAA Briefs No.12. ISAAA, Ithaca, NY.
11. Joint FAO/WHO Expert Consultation on Foods Derived from Biotechnology, 2000. Safety aspects of genetically modified foods of plant origin, World Health Organization, Geneva, pp. 1-23.
12. Lavrik P.B., Bartnicki D.E., Feldman J., Hammond B.G., Keck P.J., Love S.L., Naylor M.W., Rogan G.J., Sims S.R., Fuchs R.L. Safety assessment of potatoes resistant to Colorado potato beetle. Engel K.H., Takeoka G.R., Teranishi R. Genetically Modified Foods, Safety Issues. 1995;148-158 ACS, Washington, DC.
13. Losey J.E., Rayor L.S., Carter M.E. Transgenic pollen harms monarch larvae. Nature. 399:1999;214.
14. Maron D.M., Ames B.N. Revised methods for the Salmonella mutagenicity test. Mutat. Res. 113:1983;173-215.
15. Ming X.T., Gu H.Y., Pan N.S., Zhu Y.X., Sun B.J., Chen Z.L. Field release and biosafety assessment of transgenic plants. JIRCAS-Int. Symp. Ser. 5:1997;279-289.
16. Nordlee J.A., Taylor S.L., Townsend J.A., Thomas L.A., Bush R.K. Identification of Brasil nut allergen in transgenic soybeans. New Engl. J. Med. 334:1996;688-692.
17. Padgette S.R., Taylor N.B., Nida D.L., Bailey M.R., MacDonald J., Holden L.R., Fuchs R.L. The composition of glyphosate-tolerant soybean seeds is equivalent to that of conventional soybeans. J. Nutr. 126:1996;702-716.
18. Pusztai A., Bardocz G.G., Alonso R., Chrispeels M.J., Schroeder H.E., Tabe L.M., Higgins T.L. Expression of the insecticidal bean alpha-amylase inhibitor transgene has minimal detrimental effect on the nutritional value of peas fed to rats at 30% of the diet. J. Nutr. 129:1999;1597-1603.
19. Redenbaugh K., Hiatt W., Martineau B., Kramer M., Sheehy R., Sanders R., Houck C., Emlay D. Safety Assessment of Genetically Engineered Fruits and Vegetables: A Case Study of the Flavr Savr™ Tomato. 1992;4-31 CRC Press, Boca Raton, FL.
20. Reed A.J., Kretzmer K.A., Naylor M.W., Finn R.F., Magin K.M., Hammond B.G., Leimgruber R.M., Rogers S.G., Fuchs R.L. A safety assessment of 1-aminocyclopropane-l-carboxylic acid deaminase (ACCd) protein expressed in delayed ripening tomatoes. J. Agric. Food Chem. 44:1996;388-394.
21. Sanders P.R., Lee T.C., Groth M.E., Astwood J.D., Fuchs R.L. Safety assessment of the insect-protected corn. Thomas J.A. Biotechnology and Safety Assessment. second ed:1998;241-256 Taylor & Francis.
22. Wang Y.W., Yang M.Z., Pan N.S., Chen Z.L. Plant regeneration and transformation of sweet pepper (Capsicum frutescens). Acta Bot. Sin. 33:1991;780-786.
23. WHO GEMS/Food Regional Diets, 1998. Global Environment Monitoring System/Food Contamination Monitoring and Assessment Programme, Document WHO/FSF/FOS/98.3, World Health Organization, Geneva, pp. 1-22.
24. Wu, G., 1992. The expression of CMV-cp gene in transgenic tomato plants. M.S. thesis, Peking University.
25. Yang R.C., Xu H.L., Yu W.G., Lu C.G., Long M.S., Liu C.Q., Pan N.S., Chen Z.L. Transgenic tomato expressing CMV-CP gene and its resistance to CMV. Acta Agric. Jiangsu. 11:1995;42-46.
26. Zhu Y.X., Ou-Yang W.J., Zhang Y.F., Chen Z.L. Transgenic sweet pepper plants from Agrobacterium mediated transformation. Plant Cell Rep. 16:1996;71-75.