Inhibition of peptidases in the control of blood pressure

Essays in Biochemistry

Volumn 38, Issue , 2002, Pages 129-139

  Kubota, Eiji ^a   Dean, Rachel G ^a   Balding, Leanne C ^a   Burrell, Louise M ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; ANTIHYPERTENSIVE AGENT; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRILAT; MDL 100173; MEMBRANE METALLOENDOPEPTIDASE; OMAPATRILAT; PEPTIDASE; SCH 424345; THIORPHAN; VASOPEPTIDASE INHIBITOR; ZINC;

ATHEROSCLEROSIS; BLOOD PRESSURE; CHRONIC KIDNEY FAILURE; DIABETIC NEPHROPATHY; ENDOTHELIUM LESION; ENZYME INHIBITION; HEART FAILURE; HUMAN; HYPERTENSION; MEMBRANE; NONHUMAN; PHYSIOLOGY; PROTEIN DEGRADATION; REGULATORY MECHANISM; REVIEW;

EID: 0038394534     PISSN: 00711365     EISSN: None     Source Type: Journal    
DOI: 10.1042/bse0380129     Document Type: Review

References (18)

1. Johnston, C.I., Hodsman, P.G., Kohzuki, M., Casley, D.J., Fabris, B. & Phillips, P.A. (1989) Interaction between atrial natriuretic peptide and the renin angiotensin aldosterone system. Endogenous antagonists. Am. J. Med. 87, 24S-28S
2. Levin, E.R., Gardner, D.G. & Samson, W.K. (1998) Mechanisms of disease - natriuretic peptides. N. EngI. J. Med. 339, 321-328
3. Cushman, D.W. & Ondetti, M.A. (1999) Design of angiotensin converting enzyme inhibitors. Nat. Med. 5, 1110-1112
4. Turner, A.J., Isaac, R.E. & Coates, D. (2001) The neprilysin (NEP) family of zinc metalloendopeptidoses: genomics and function. Bioessays 23, 261-269
5. Burrell, L.M. & Johnston, C.I. (2000) Clinical trials of ACE inhibitors: pathogenetic insights and therapeutic advances. In Drugs, Enzymes and Receptors of the Renin - Angiotensin System: Celebrating a Century of Discovery (Husain, A. and Graham, R.M., eds), pp. 191-200, Harwood, Amsterdam
6. Roques, B.P., Noble, F., Dauge, V., Fournie-Zaluski, M.-C. & Beaumont, A. (1993) Neutral endopeptidase 24. II: structure, inhibition and experimental and clinical pharmacology. Pharmacol. Rev. 45, 118-146
7. Bralet, J. & Schwartz, J.-C. (2001) Vasopeptidase inhibitors: an emerging class of cardiovascular drugs. Trends Pharmacol. Sci. 22, 106-109
8. Burrell, L.M., Chai, S.Y. & Johnston, C.I. (1996) Tissue and cellular renin-angiotensin systems In Handbook of Hypertension (Zanchetti, A. & Mancia, G., eds), pp. 822-841, Elsevier, Amsterdam
9. Johnston, C.I. (1994) Tissue angiotensin converting enzyme in cardiac and vascular hypertrophy, repair and remodeling. Hypertension 23, 258-268
10. Kerr, M.A. & Kenny, A.J. (1974) The purification and specificity of a neutral endopeptidase from rabbit kidney brush border. Biochem. J. 137, 477-488
11. Watanabe, Y., Nakajima, K., Shimamori, Y. & Fujimoto, Y. (1997) Comparison of the hydrolysis of the three types of natriuretic peptides by human kidney neutral endopeptidase 24. II. Biochem. Mol. Med. 61, 47-51
12. Richards, A.M., Crozier, I.G., Kosoglou, T., Railings, M., Espiner, E.A., Nicholls, M.G., Yandle, T.G., Ikram, H. & Frampton, C. (1993) Endopeptidase-24. II inhibition by SCH-42495 in essential hypertension. Hypertension 22, 119-126
13. Corti, R., Burnett, J.C., Rouleau, J.L., Ruschitzka, F. & Luscher, T.F. (2001) Vasopeptidase inhibitors - a new therapeutic concept in cardiovascular disease? Circulation 104, 1856-1862
14. Farina, N.K., Johnston, C.I. & Burrell, L.M. (2000) Reversal of cardiac hypertrophy and fibrosis by S21402, a dual inhibitor of neutral endopeptidase and angiotensin converting enzyme in SHRs. J. Hypertens. 18, 749-755
15. Burrell, L.M., Droogh, J., Manintveld, O., Rockell, M.D., Farina, N.K. & Johnston, C.I. (2000) Antihypertensive and antihypertrophic effects of omapatrilat in SHR. Am. J. Hypertens. 13, 1110-1116
16. Trippodo, N.C., Robl, J.A., Asaad, M.M., Fox, M., Panchal, B.C. & Schaeffer, T.R. (1998) Effects of omapatrilat in low, normal and high renin experimental hypertension. Am. J. Hypertens. 11, 363-372
17. Cooper, M.E. & Johnston, C.I. (2000) Optimizing treatment of hypertension in patients with diabetes. JAMA, J. Am. Med. Assoc 283, 3177-3179
18. Cao, Z.M., Burrell, L.M., Tikkanen, I., Bonnet, F., Cooper, M.E. & Gilbert, R.E. (2001) Vasopeptidase inhibition attenuates the progression of renal injury in subtotal nephrectomized rats. Kidney Int. 60, 715-721