Alternative surgical procedures to help drug-resistant epilepsy - A review

Epileptic Disorders

Volumn 5, Issue 2, 2003, Pages 63-75

  Polkey, Charles E ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Callosotomy; Epilepsy surgery; Intracerebral stimulation; Radiosurgery; Subpial transection; Vagus nerve

Indexed keywords

ANTICONVULSIVE AGENT;

CALLOSTOMY; COUGHING; DISEASE SEVERITY; ELECTROENCEPHALOGRAM; EPILEPSY; HOARSENESS; HUMAN; METHODOLOGY; MORBIDITY; MORTALITY; PARESTHESIA; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RADIOSURGERY; REVIEW; SCLEROSIS; SEIZURE; SIDE EFFECT; STEREOTAXIC SURGERY; SURGICAL TECHNIQUE; VAGUS NERVE STIMULATION;

BRAIN; CORPUS CALLOSUM; ELECTRIC STIMULATION THERAPY; ELECTRODES, IMPLANTED; EPILEPSY; HUMANS; OUTCOME AND PROCESS ASSESSMENT (HEALTH CARE); RADIOSURGERY; VAGUS NERVE;

EID: 0038384004     PISSN: 12949361     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (126)

1. Barcia-Salorio JL, Barcia JA, Hernandez G, Lopez-Gomez L. Radiosurgery of epilepsy. Long-term results. Acta Neurochir Suppl (Wien) 1994; 62: 111-3.
2. Chen ZF, Kamiryo T, Henson SL, et al. Anticonvulsant effects of gamma surgery in a model of chronic spontaneous limbic epilepsy in rats. J Neurosurg 2001; 94: 270-80.
3. Maesawa S, Kondziolka D, Dixon CE, Balzer J, Fellows W, Lunsford LD. Subnecrotic stereotactic radiosurgery controlling epilepsy produced by kainic acid injection in rats. J Neurosurg 2000; 93: 1033-40.
4. Regis J, Bartolomei F, Hayashi M, Roberts D, Chauvel P, Peragut JC. The role of gamma knife surgery in the treatment of severe epilepsies. Epileptic Disord 2000; 2: 113-22.
5. Regis J, Bartolomei F, Rey M, Hayashi M, Chauvel P, Peragut JC. Gamma knife surgery for mesial temporal lobe epilepsy. J Neurosurg 2000; 93 Suppl 3: 141-6.
6. Kawai K, Suzuki I, Kurita H, Shin M, Arai N, Kirino T. Failure of low-dose radiosurgery to control temporal lobe epilepsy. J Neurosurg 2001; 95: 883-7.
7. Regis J, Bartolomei F, de Toffol B, et al. Gamma knife surgery for epilepsy related to hypothalamic hamartomas. Neurosurgery 2000; 47: 1343-51.
8. Whang CJ, Kwon Y. Long-term follow-up of stereotactic Gamma Knife radiosurgery in epilepsy. Stereotact Funct Neurosurg 1996; 66 Suppl 1: 349-56.
9. Van Wagenen WP, Herren RY. Surgical division of commissural pathways in the corpus callosum. Arch Neurol Psychiatry 1940; 44: 740-59.
10. Anonymous. A global survey on epilepsy surgery, 1980-1990: a report by the Commission on Neurosurgery of Epilepsy, the International League Against Epilepsy. Epilepsia 1997; 38: 249-55.
11. Engel J, Van Ness PC, Rasmussen T, Ojemann LM. Outcome with respect to epileptic seizures. In: Engel J, editor. Surgical Treatment of the Epilepsies. New York: Raven Press, 1993: 609-22.
12. Spencer SS, Spencer DD, Glaser GH, Williamson PD, Mattson RH. More intense focal seizure types after callosal section: the role of inhibition. Ann Neurol 1984; 6: 686-93.
13. Matsuzaka T, Ono K, Baba H, et al. Quantitative EEG analyses and surgical outcome after corpus callosotomy. Epilepsia 1999; 40: 1269-78.
14. Joseph R. Reversal of cerebral dominance for language and emotion in a corpus callosotomy patient. J Neurol Neurosurg Psychiatry 1986; 49: 628-34.
15. Sass KJ, Spencer SS, Spencer DD, Novelly RA, Williamson PD, Mattson RH. Corpus callosotomy for epilepsy. II Neurologic and neuropsychological outcome. Neurology 1988; 38: 24-8.
16. Fiol ME, Gates JR, Mireles R, Maxwell RE, Erickson DM. Value of intraoperative EEG changes during corpus callosotomy in predicting surgical results. Epilepsia 1993; 34: 74-8.
17. Sakas DE, Phillips J. Anterior callosotomy in the management of intractable epileptic seizures: significance of the extent of resection. Acta Neurochirurgica 1996; 138: 700-7.
18. Kuzniecky R, Andermann F, Guerrini R. The epileptic spectrum in the congenital bilateral perisylvian syndrome. CBPS Multicenter Collaborative Study. Neurology 1994; 44: 379-85.
19. Pallini R, Aglioti S, Tassinari G, Berlucchi G, Colosimo C, Rossi GF. Callosotomy for intractable epilepsy from bihemispheric cortical dysplasias. Acta Neurochirurgica 1995; 132: 79-86.
20. Palmini A, Andermann F, Aicardi J, et al. Diffuse cortical dysplasia, or the 'double cortex' syndrome: the clinical and epileptic spectrum in 10 patients. Neurology 1991; 41: 1656-62.
21. Bernasconi A, Martinez V, Rosa-Neto P, et al. Surgical resection for intractable epilepsy in "double cortex" syndrome yields inadequate results. Epilepsia 2001; 42: 1124-9.
22. Daszkiewicz P, Dabrowski D, Bachanski M. [Callosotomy in the treatment of "catastrophic" drug-resistant epilepsy in children]. Neurol Neurochir Pol 1999; 33: 839-46.
23. Ma X, Liporace J, O'Connor MJ, Sperling MR. Neurosurgical treatment of medically intractable status epilepticus. Epilepsy Res 2001; 46: 33-8.
24. Kwan SY, Wong TT, Chang KP, et al. Postcallosotomy seizure outcome in hemiconvulsion-hemiatrophy-epilepsy syndrome. Zhonghua Yi Xue Za Zhi (Taipei) 2000; 63: 503-11.
25. Fandino-Franky J, Torres M, Narino D, Fandino J. Corpus callosotomy in Colombia and some reflections on care and research among the poor in developing countries. Epilepsia 2000; 41 Suppl 4: S22-S27.
26. Kamida T, Baba H, Ono K, Ono T, Yonekura M. [Staged total callosotomy for medically intractable seizures]. No To Shinkei 2000; 52: 1085-90.
27. Kwan SY, Wong TT, Chang KP, et al. Seizure outcome after corpus callosotomy: the Taiwan experience. Childs Nerv Syst 2000; 16: 87-92.
28. Rossi GF, Colicchio G, Marchese E, Pompucci A. Callosotomy for severe epilepsies with generalized seizures: outcome and prognostic factors. Acta Neurochirurgica 1996; 138: 221-7.
29. Quattrini A, Del Pesce M, Provinciali L, et al. Mutism in 36 patients who underwent callosotomy for drug- resistant epilepsy. J Neurosurg Sci 1997; 41: 93-6.
30. Zaidel D, Sperry RW. Some long-term motor effects of cerebral commissurotomy in man. Neuropsychologia 1977; 15: 193-204.
31. Roberts DW. The role of callosal section in surgical treatment of epilepsies. Neurosurg Clin N Am 1993; 4: 293-300.
32. Sass KJ, Spencer DD, Spencer SS, Novelly RA, Williamson PD, Mattson RH. Corpus callosotomy for epilepsy. II. Neurologic and neuropsychological outcome. Neurology 1988; 38: 24-8.
33. Oguni H, Olivier A, Andermann F, Comair J. Anterior callosotomy in the treatment of medically intractable epilepsies: a study of 43 patients with a mean follow-up of 39 months. Ann Neurol 1991; 30: 357-64.
34. Pressler R, Binnie CD, Polkey CE. Return of generalised seizures and discharges after callosotomy. Epilepsia 1996; 37: 209.
35. Maehara T, Shimizu H. Surgical outcome of corpus callosotomy in patients with drop attacks. Epilepsia 2001; 42: 67-71.
36. Pinard JM, Delalande O, Chiron C, et al. Callosotomy for epilepsy after West syndrome. Epilepsia 1999; 40: 1727-34.
37. Mamelak AN, Barbaro NM, Walker JA, Laxer KD. Corpus callosotomy: a quantitative study of the extent of resection, seizure control, and neuropsychological outcome. J Neurosurg 1993; 5: 688-95.
38. Rougier A, Claverie B, Marchal C, Pedespan JM, Loiseau P. [Social outcome of 20 anterior callosotomies for drug-resistant epilepsy]. Neurochirurgie 1995; 41: 413-8.
39. Sassower KC, Rollinson DC, Duchowny M. Outcome of corpus callosotomy and other pediatric epilepsy surgery: parental perceptions. Epileptic Disord 2001; 3: 197-202.
40. Morrell F, Whisler WW, Bleck TP. Multiple subpial transection. A new approach to the surgical treatment of focal epilepsy. J Neurosurg 1989; 70: 231-9.
41. Smith MC. Multiple subpial transection in patients with extratemporal epilepsy. Epilepsia 1998; 39 Suppl 4: S81-S89.
42. Spencer SS, Schramm J, Wyler A, et al. Multiple subpial transection for intractable partial epilepsy: an international meta-analysis. Epilepsia 2002; 43: 141-5.
43. Orbach D, Romanelli P, Devinsky O, Doyle W. Late seizure recurrence after multiple subpial transections. Epilepsia 2001; 42: 1316-9.
44. D'Giano CH, Del CG, Pomata H, Rabinowicz AL. Treatment of refractory partial status epilepticus with multiple subpial transection: case report. Seizure 2001; 10: 382-5.
45. Otsubo H, Chitoku S, Ochi A, et al. Malignant rolandicsylvian epilepsy in children: diagnosis, treatment, and outcomes. Neurology 2001; 57: 590-6.
46. Shimizu H, Maehara T. Neuronal disconnection for the surgical treatment of pediatric epilepsy. Epilepsia 2000; 41 Suppl 9: 28-30.
47. Morrell F, Whisler WW, Smith MC. Multiple subpial transection in Rasmussen's encephalitis. In: Andermann F, ed. Chronic Encephalitis and Epilpesy: Rasmussen's Syndrome. Boston: Butterworth-Heinemann, 1991: 219-33.
48. Schramm J, Aliashkevich AF, Grunwald T. Multiple subpial transections: outcome and complications in 20 patients who did not undergo resection. J Neurosurg 2002; 97: 39-47.
49. Shimizu T, Maehara T, Hino T, et al. Effect of multiple subpial transection on motor cortical excitability in cortical dysgenesis. Brain 2001; 124(Pt 7): 1336-49.
50. Morrell F, Whisler WW, Smith MC, et al. Landau-Kleffner syndrome. Treatment with subpial intracortical transection. Brain 1995; 118(Pt 6): 1529-46.
51. Sobel DF, Aung M, Otsubo H, Smith MC. Magnetoencephalography in children with Landau-Kleffner syndrome and acquired epileptic aphasia. Am J Neuroradiol 2000; 21: 301-7.
52. Paetau R, Granstrom ML, Blomstedt G, et al. Magnetoencephalography in presurgical evaluation of children with the Landau-Kleffner syndrome. Epilepsia 1999; 40: 326-35.
53. Robinson RO, Baird G, Robinson G, Simonoff E. Landau-Kleffner syndrome: course and correlates with outcome. Dev Med Child Neurol 2001; 43: 243-7.
54. Grote CL, Van Slyke P, Hoeppner JA. Language outcome following multiple subpial transection for Landau-Kleffner syndrome. Brain 1999; 122(Pt 3): 561-6.
55. Irwin K, Birch V, Lees J, et al. Multiple subpial transection in Landau-Kleffner syndrome. Dev Med Child Neurol 2001; 43: 248-52.
56. Lewine JD, Andrews R, Chez M, et al. Magnetoencephalographic patterns of epileptiform activity in children with regressive autism spectrum disorders. Pediatrics 1999; 104(3 Pt 1): 405-18.
57. Proctor M, Gale K. Basal Ganglia and Brainstem Anatomy and Physiology. In: Engel J, Pedley TA, ed. Epilepsy: A Comprehensive Textbook. Philadelphia: Lippincott-Raven, 1997: 353-368.
58. Fisher RS. Animal models of the epilepsies. Brain Res Rev 1989; 14: 245-78.
59. Krahl SE, Clark KB, Smith DC, Browning RA. Locus coeruleus lesions suppress the seizure-attenuating effects of vagus nerve stimulation. Epilepsia 1998; 39: 709-14.
60. Zagon A, Kemeny AA. Slow hyperpolarization in cortical neurons: a possible mechanism behind vagus nerve simulation therapy for refractory epilepsy? Epilepsia 2000; 41: 1382-9.
61. Henry TR, Votaw JR, Pennell PB, et al. Acute blood flow changes and efficacy of vagus nerve stimulation in partial epilepsy. Neurology 1999; 52: 1166-73.
62. Van Laere K, Vonck K, Boon P, Brans B, Vandekerckhove T, Dierckx R. Vagus nerve stimulation in refractory epilepsy: SPECT activation study. J Nucl Med 2000; 41: 1145-54.
63. Van Laere K, Vonck K, Boon P, Versijpt J, Dierckx R. Perfusion SPECT Changes After Acute and Chronic Vagus Nerve Stimulation in Relation to Prestimulus Condition and Long-Term Clinical Efficacy. J Nucl Med 2002; 43: 733-44.
64. Narayanan JT, Watts R, Haddad N, Labar DR, Li PM, Filippi CG. Cerebral Activation during Vagus Nerve Stimulation: A Functional MR Study. Epilepsia 2002; 43: 1509-14.
65. Koo B. EEG changes with vagus nerve stimulation. J Clin Neurophysiol 2001; 18: 434-41.
66. Olejniczak PW, Fisch BJ, Carey M, Butterbaugh G, Happel L, Tardo C. The effect of vagus nerve stimulation on epileptiform activity recorded from hippocampal depth electrodes. Epilepsia 2001; 42: 423-9.
67. Dempsey EW, Morison RS. The production of rythmically recurrent cortical potentials after localised thalamic stimulation. Am J Physiol 1942; 135: 293-300.
68. Monnier M, Kalberer M, Krupp P. Functional antagonism between diffuse reticular and intralaminary recruiting projections in the medial thalamus. Exp Neurol 1960; 2: 271-89.
69. Avanzini G, Panzica F, de Curtis M. The role of the thalamus in vigilance and epileptogenic mechanisms. Clin Neurophysiol 2000; 111: S19-S26.
70. Meeren HK, Pijn JP, van Luijtelaar EL, Coenen AM, Lopes da Silva FH. Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats. J Neurosci 2002; 22: 1480-95.
71. Steriade M, Amzica F, Neckelmann D, Timofeev I. Spikewave complexes and fast components of cortically generated seizures. II. Extra- and intracellular patterns. J Neurophysiol 1998; 80: 1456-79.
72. Timofeev I, Grenier F, Steriade M. Spike-wave complexes and fast components of cortically generated seizures. IV. Paroxysmal fast runs in cortical and thalamic neurons. J Neurophysiol 1998; 80: 1495-513.
73. Mirski MA, Rossell LA, Terry JB, Fisher RS. Anticonvulsant effect of anterior thalamic high frequency electrical stimulation in the rat. Epilepsy Res 1997; 28: 89-100.
74. Mirski MA, Ferrendelli JA. Anterior thalamic mediation of generalized pentylenetetrazol seizures. Brain Res 1986; 399: 212-23.
75. Sherman DL, Tsai YC, Rossell LA, Mirski MA, Thakor NV. Spectral analysis of a thalamus-to-cortex seizure pathway. IEEE Trans Biomed Eng 1997; 44: 657-64.
76. Fisher RS, Uematsu S, Krauss GL, et al. Placebo-controlled pilot study of centromedian thalamic stimulation in treatment of intractable seizures. Epilepsia 1992; 33: 841-51.
77. Vercueil L, Benazzouz A, Deransart C, et al. High-frequency stimulation of the subthalamic nucleus suppresses absence seizures in the rat: comparison with neurotoxic lesions. Epilepsy Res 1998; 31: 39-46.
78. Krauss JK, Loher TJ, Weigel R, Capelle HH, Weber S, Burgunder JM. Chronic stimulation of the globus pallidus internus for treatment of non-dYT1 generalized dystonia and choreoathetosis: 2-year follow up. J Neurosurg 2003; 98: 785-92.
79. Handforth A, DeGiorgio CM, Schachter SC, et al. Vagus nerve stimulation therapy for partial-onset seizures: a randomized active-control trial. Neurology 1998; 51: 48-55.
80. Morris GL, III, Mueller WM. Long-term treatment with vagus nerve stimulation in patients with refractory epilepsy. The Vagus Nerve Stimulation Study Group E01-E05. Neurology 1999; 53: 1731-5.
81. Lundgren J, Ekberg O, Olsson R. Aspiration: a potential complication to vagus nerve stimulation. Epilepsia 1998; 39: 998-1000.
82. Tatum WO, Moore DB, Stecker MM, et al. Ventricular asystole during vagus nerve stimulation for epilepsy in humans. Neurology 1999; 52: 1267-9.
83. Lotvall J, Lunde H, Augustinson LE, Hedner T, Svedmyr N, Ben Menachem E. Airway effects of direct left-sided cervical vagal stimulation in patients with complex partial seizures. Epilepsy Res 1994; 18: 149-54.
84. Annegers JF, Coan SP, Hauser WA, Leestma J. Epilepsy, vagal nerve stimulation by the NCP system, all-cause mortality, and sudden, unexpected, unexplained death. Epilepsia 2000; 41: 549-53.
85. Morris G, Pallagi J. Long-term follow-up of 454 patients with epilepsy receiving vagus nerve stimulation. Epilepsia 1998; 39[S6]: 93.
86. Privitera MD, Welty TE, Ficker DM, Welge J. Vagus nerve stimulation for partial seizures (Cochrane Review). Cochrane Database Syst Rev 2002; (1): CD002896.
87. Blumer D, Davies K, Alexander A, Morgan S. Major psychiatric disorders subsequent to treating epilepsy by vagus nerve stimulation. Epilepsy Behav 2001; 2: 466-72.
88. Boon P, Vonck K, Van Walleghem P, D'Have M, Caemaert J, De Reuck J. Vagus nerve stimulation for epilepsy, clinical efficacy of programmed and magnet stimulation. Acta Neurochir Suppl 2002; 79: 93-8.
89. Kuba R, Guzaninova M, Brazdil M, Novak Z, Chrastina J, Rektor I. Effect of vagal nerve stimulation on interictal epileptiform discharges: a scalp EEG study. Epilepsia 2002; 43: 1181-8.
90. Murphy JV. Left vagal nerve stimulation in children with medically refractory epilepsy. The Pediatric VNS Study Group. J Pediatr 1999; 134: 563-6.
91. Helmers SL, Wheless JW, Frost M, Gates J, Levisohn P, Tardo C, et al. Vagus nerve stimulation therapy in pediatric patients with refractory epilepsy: retrospective study. J Child Neurol 2001; 16: 843-8.
92. Patwardhan RV, Stong B, Bebin EM, Mathisen J, Grabb PA. Efficacy of vagal nerve stimulation in children with medically refractory epilepsy. Neurosurgery 2000; 47: 1353-7.
93. Frost M, Gates J, Helmers SL, et al. Vagus nerve stimulation in children with refractory seizures associated with Lennox-Gastaut syndrome. Epilepsia 2001; 42: 1148-52.
94. Andriola MR, Vitale SA. Vagus Nerve Stimulation in the Developmentally Disabled. Epilepsy Behav 2001; 2: 129-34.
95. Gates J, Huf R, Frost M. Vagus Nerve Stimulation for Patients in Residential Treatment Facilities. Epilepsy Behav 2001; 2: 563-7.
96. Alsaadi TM, Laxer KD, Barbaro NM, Marks WJ, Jr, Garcia PA. Vagus nerve stimulation for the treatment of bilateral independent temporal lobe epilepsy. Epilepsia 2001; 42: 954-6.
97. Koutroumanidis M, Binnie CD, Hennessy MJ, et al. VNS in patients with previous unsuccessful resective epilepsy surgery: antiepileptic and psychotropic effects. Acta Neurol Scand 2003; 107: 117-21.
98. Ergene E, Behr PK, Shih JJ. Quality-of-Life Assessment in Patients Treated with Vagus Nerve Stimulation. Epilepsy Behav 2001; 2: 284-7.
99. Boon P, Vonck K, Vandekerckhove T, D'Have M, Nieuwenhuis L, Michielsen G, et al. Vagus nerve stimulation for medically refractory epilepsy; efficacy and cost-benefit analysis. Acta Neurochir (Wien) 1999; 141: 447-52.
100. Majoie HJ, Berfelo MW, Aldenkamp AP, Evers SM, Kessels AG, Renier WO. Vagus nerve stimulation in children with therapy-resistant epilepsy diagnosed as Lennox-Gastaut syndrome: clinical results, neuropsychological effects, and cost-effectiveness. J Clin Neurophysiol 2001; 18: 419-28.
101. Fandino-Franky J, Torres M, Narino D, Fandino J. Corpus callosotomy in Colombia and some reflections on care and research among the poor in developing countries. Epilepsia 2000; 41 Suppl 4: 2001; S22-S27.
102. Cooper IS, Amin I, Riklan M, Waltz JM, Poon TP. Chronic cerebellar stimulation in epilepsy. Clinical and anatomical studies. Arch Neurol 1976; 33: 559-70.
103. Upton AR, Cooper IS, Springman M, Amin I. Suppression of seizures and psychosis of limbic system origin by chronic stimulation of anterior nucleus of the thalamus. Int J Neurol 1986; 19: 223-30.
104. Van Buren JM, Wood JH, Oakley J, Hambrecht F. Preliminary evaluation of cerebellar stimulation by double-blind stimulation and biological criteria in the treatment of epilepsy. J Neurosurg 1978; 48: 407-16.
105. Wright GDS, McLellan DL, Brice JG. A double-blind trial of chronic cerebellar stimulation in twelve patients with severe epilepsy. J Neurol Neurosurg Psychiat 1985; 47: 769-74.
106. Fisher RS, Mirski M, Krauss GL. Brain stimulation. In: Engel JJ, Pedley TA, ed. Epilepsy: A Comprehensive Textbook. Philadelphia: Lippincott-Raven, 1997: 1867-75.
107. Ciganek L, Sramka M, Nadvornik P, Fritz G. Effects of stereotactic operations in the treatment of epilepsies-neurological aspects. Acta Neurochir (Wien) 1976; 23: 201-4.
108. Sramka M, Fritz G, Gajdosova D, Nadvornik P. Central stimulation treatment of epilepsy. Acta Neurochir Suppl (Wien) 1980; 30: 183-7.
109. Velasco F, Velasco M, Ogarrio C, Fanghanel G. Electrical stimulation of the centromedian thalamic nucleus in the treatment of convulsive seizures: a preliminary report. Epilepsia 1987; 28: 421-30.
110. Gale K. Role of the substantia nigra in GABA-mediated anticonvulsant actions. Adv Neurol 1986; 44: 343-64.
111. Benabid AL, Minotti L, Koudsie A, de Saint MA, Hirsch E. Antiepileptic effect of high-frequency stimulation of the subthalamic nucleus (corpus luysi) in a case of medically intractable epilepsy caused by focal dysplasia: a 30-month follow-up: technical case report. Neurosurgery 2002; 50: 1385-91.
112. Chkhenkeli SA, Chkhenkeli IS. Effects of therapeutic stimulation of nucleus caudatus on epileptic electrical activity of brain in patients with intractable epilepsy. Stereotact Funct Neurosurg 1997; 69(1-4 Pt 2): 221-4.
113. Sramka M, Chkhenkeli SA. Clinical experience in intraoperational determination of brain inhibitory structures and application of implanted neurostimulators in epilepsy. Stereotact Funct Neurosurg 1990; 54-5: 56-9, 1990; 54: 56-9.
114. Velasco F, Velasco M, Velasco AL, Jimenez F, Genton P, Portera-Sanchez A. Effect of chronic electrical stimulation of the centromedian thalamic nuclei on various intractable seizure patterns: I. Clinical seizures and paroxysmal EEG activity. Epilepsia 1993; 34: 1052-64.
115. Velasco F, Velasco M, Jimenez F, et al. Predictors in the treatment of difficult-to-control seizures by electrical stimulation of the centromedian thalamic nucleus. Neurosurgery 2000; 47: 295-304.
116. Velasco AL, Boleaga B, Santos N, Velasco F, Velasco M. Electroencephalographic and magnetic resonance correlations in children with intractable seizures of Lennox-Gastaut syndrome and epilepsia partialis continua. Epilepsia 1993; 34: 262-70.
117. Velasco M, Velasco F, Velasco AL, Velasco G, Jimenez F. Effect of chronic electrical stimulation of the centromedian thalamic nuclei on various intractable seizure patterns: II. Psychological performance and background EEG activity. Epilepsia 1 1993; 34: 1065-74.
118. Velasco F, Velasco M, Jimenez F, Velasco AL, Marquez I. Stimulation of the central median thalamic nucleus for epilepsy. Stereotact Funct Neurosurg 2001; 77: 228-32.
119. Hodaie M, Wennberg RA, Dostrovsky JO, Lozano AM. Chronic anterior thalamus stimulation for intractable epilepsy. Epilepsia 2002; 43: 603-8.
120. Chabardes S, Kahane P, Minotti L, Koudsie A, Hirsch E, Benabid AL. Deep brain stimulation in epilepsy with particular reference to the subthalamic nucleus. Epileptic Disord 2002; 4: S83-S93.
121. Velasco AL, Velasco M, Velasco F, Menes D, Gordon F, Rocha L, et al. Subacute and chronic electrical stimulation of the hippocampus on intractable temporal lobe seizures: preliminary report. Arch Med Res 2000; 31: 316-28.
122. Velasco M, Velasco F, Velasco AL, et al. Subacute electrical stimulation of the hippocampus blocks intractable temporal lobe seizures and paroxysmal EEG activities. Epilepsia 2000; 41: 158-69.
123. Vonck K, Boon P, Achten E, De Reuck J, Caemaert J. Long-term amygdalohippocampal stimulation for refractory temporal lobe epilepsy. Ann Neurol 2002; 52: 556-65.
124. Peters TE, Bhavaraju NC, Frei MG, Osorio I. Network system for automated seizure detection and contingent delivery of therapy. J Clin Neurophysiol 2001; 18: 545-9.
125. Bergey GK, Britton JW, Cascino GD, et al. Implementation of an externally responsive neurostimulator system (eRNS) in patients with intractable epilepsy undergoing intracraniial seizure monitoring. AES 2002; 6-12-2002.
126. Osorio I, Frei MG, Giftakis J, et al. Performance reassessment of a real-time seizure-detection algorithm on long ECoG series. Epilepsia 2000; 43: 1522-35.