Locus coeruleus lesions suppress the seizure-attenuating effects of vagus nerve stimulation

Epilepsia

Volumn 39, Issue 7, 1998, Pages 709-714

  Krahl, Scott E ^a   Clark, Kevin B ^b   Smith, Douglas C ^b   Browning, Ronald A ^c  

^a VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

^b SOUTHERN ILLINOIS UNIVERSITY   (United States)

^c SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anticonvulsant; Epilepsy; Locus coeruleus; Norepinephrine; Vagus nerve

Indexed keywords

ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ANTINOCICEPTION; ARTICLE; DOPAMINE BRAIN LEVEL; EPILEPSY; FEMALE; LOCUS CERULEUS; NERVE INJURY; NONHUMAN; NORADRENALIN BRAIN LEVEL; PRIORITY JOURNAL; RAT; TREATMENT OUTCOME; VAGUS NERVE STIMULATION;

ANIMALS; ELECTRIC STIMULATION THERAPY; ELECTROSHOCK; FEMALE; HYDROXYDOPAMINES; LIDOCAINE; LOCUS COERULEUS; NOREPINEPHRINE; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; SEVERITY OF ILLNESS INDEX; VAGUS NERVE;

EID: 0031821408     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1528-1157.1998.tb01155.x     Document Type: Article

References (32)

1. Vagus Nerve Stimulation Study Group. A randomized controlled trial of chronic vagus nerve stimulation for treatment of medically intractable seizures. Neurology 1995;45:224-30.
2. Zanchetti A, Wang SC, Moruzzi G. The effect of vagal afferent stimulation on the EEG pattern of the cat. Electroencephalogr Clin Neurophysiol 1952;4:357-61.
3. Stoica I, Tudor I. Effects of vagus afferents on strychninic focus of coronal gyrus. Rev Roum Neurol 1967;4:287-95.
4. Stoica I, Tudor I. Vagal trunk stimulation influences on epileptic spiking focus activity. Rev Roum Neurol 1968;5:203-10.
5. Woodbury DM, Woodbury JW. Effects of vagal stimulation on experimentally induced seizures in rats. Epilepsia 1990;31(suppl 2):S7-19.
6. Woodbury JW, Woodbury DM. Vagal stimulation reduces the severity of maximal electroshock seizures in intact rats: use of a cuff electrode for stimulating and recording. Pacing Clin Electrophysiol 1991;14:94-107.
7. McLachlan RS. Suppression of interictal spikes and seizures by stimulation of the vagus nerve. Epilepsia 1993;34:918-23.
8. Godlevsky L, Shandra A, Mazarati A. Effects of vagus stimulation on epileptic activity in rats. Epilepsia 1994;35(suppl 7):39.
9. Zabara J. Inhibition of experimental seizures in canines by repetitive vagal stimulation. Epilepsia 1992;33:1005-12.
10. Lockard JS, Congdon WC, DuCharme LL. Feasibility and safety of vagal stimulation in monkey model. Epilepsia 1990;31(suppl 2):S20-7.
11. Rutecki P. Anatomical, physiological, and theoretical basis for the antiepileptic effect of vagus nerve stimulation. Epilepsia 1990;31 (suppl 2):S1-6.
12. Randich A, Ren K, Gebhart GF. Electrical stimulation of cervical vagal afferents. II. Central relays for behavioral antinociception and arterial blood pressure decreases. J Neurophysiol 1990;64: 1115-24.
13. Ren K, Randich A, Gebhart GF. Electrical stimulation of cervical vagal afferents. I. Central relays for modulation of spinal nociceptive transmission. J Neurophysiol 1990;64:1098-114.
14. Randich A, Gebhart GF. Vagal afferent modulation of nociception. Brain Res Brain Res Rev 1992;17:77-99.
15. Libet B, Gleason CA, Wright EW, Feinstein B. Suppression of an epileptiform type of electrocortical activity in the rat by stimulation in the vicinity of the locus coeruleus. Epilepsia 1977;18:451-61.
16. Neuman RS. Suppression of penicillin-induced focal epileptiform activity by locus coeruleus stimulation: mediation by an alpha 1-adrenoceptor. Epilepsia 1986;27:359-66.
17. Jimenez-Rivera CA, Voltura A, Weiss GK. Effects of locus coeruleus stimulation on the development of kindled seizures. Exp Neurol 1987;95:13-20.
18. Flaber J, Vladyka V. Antiepileptic effects of electrical stimulation of the locus coeruleus in man. Activ Nerv Sup 1983;25:304-8.
19. Browning RA. The role of neurotransmitters in electroshock seizure models. In: Jobe PC, Laird HE, II, eds. Neurotransmitters and epilepsy. Clifton, NJ: Humana Press, 1987:277-320.
20. Browning RA, Wang C, Faingold CL. Effect of norepinephrine depletion on audiogenic-like seizures elicited by microinfusion of an excitant amino acid into the inferior colliculus of normal rats. Exp Neurol 1991;112:200-5.
21. Browning RA, Maynert EW. Effect of intracisternal 6-hydroxydopamine on seizure susceptibility in rats. Fed Proc 1978;29:966.
22. Corcoran ME, Mason ST. Role of forebrain catecholamines in amygdaloid kindling. Brain Res 1980;190:473-84.
23. McIntyre DC. Amygdala kindling in rats: facilitation after local amygdala norepinephrine depletion with 6-hydroxydopamine. Exp Neurol 1980;69:395-407.
24. Altman IM, Corcoran ME. Facilitation of neocortical kindling by depletion of forebrain noradrenaline. Brain Res 1983;270:174-7.
25. Wang C, Mishra PK, Dailey JW, Jobe PC, Browning RA. Noradrenergic terminal fields as determinants of seizure predisposition in GEPR-3s: a neuroanatomic assessment with intracerebral microinjections of 6-hydroxydopamine. Epilepsy Res 1994;18:1-9.
26. Fearon Z, Munoz FG. Development of kindling: whole-brain stimulation in rats. Exp Neurol 1985;90:268.
27. Rudzik AD, Johnson GA. Effect of amphetamine and amphetamine analogs on convulsive thresholds. In: Costa E, Gyration S, eds. International symposium on amphetamines and related compounds. New York: Raven Press, 1970.
28. Gieroba ZJ, Blessing WW. Fos-containing neurons in medulla and pons after unilateral stimulation of the afferent abdominal vagus in conscious rabbits. Neuroscience 1994;59:851-8.
29. Naritoku DK, Terry WJ, Helfert RH. Regional induction of fos immunoreactivity in the brain by anticonvulsant stimulation of the vagus nerve. Epilepsy Res 1995;22:53-62.
30. Krahl SE, Browning RA, Clark KB, Smith DC. Possible mechanism of the seizure attenuating effects of vagus nerve stimulation. Soc Neurosci Abstr 1994;20:1453.
31. Sole MJ, Hussain MN, Versteeg DHG, et al. The identification of specific brain nuclei in which catecholamine turnover is increased by left ventricular receptors during acute myocardial infarction in the rat. Brain Res 1982;235:315-25.
32. Oishi R, Suenaga N, Hidaka T, Fukuda T. Inhibitory effect of intraspinal injection of 6-hydroxydopamine on the clonic convulsion in maximal electroshock seizure. Brain Res 1979;169:189-93.