Safety of inhaled corticosteroids delivered by plastic and metal spacers

Archives of Disease in Childhood

Volumn 88, Issue 6, 2003, Pages 527-528

  Amirav, I ^b   Mansour, Y ^b   Tiosano, T ^b   Chamny, S ^b   Chirurg, S ^b   Oren, S ^b   Grossman, Z ^b   Kahana, L ^b   Kahan, E ^b   Newhouse, M T ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b IPROS Network of the Israel Ambulatory Pediatric Association   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BUDESONIDE; CORTICOSTEROID; METAL; PLASTIC; POLYPROPYLENE;

ADRENAL SUPPRESSION; AEROSOL; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE CLEARANCE; CROSSOVER PROCEDURE; DISEASE ASSOCIATION; DOSE RESPONSE; DRUG ABSORPTION; DRUG DELIVERY SYSTEM; DRUG SAFETY; ELECTRICITY; EQUIPMENT DESIGN; HUMAN; HYPOPHYSIS ADRENAL SYSTEM; INHALATION; LUNG DISEASE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STEROID THERAPY;

ANTI-INFLAMMATORY AGENTS; ASTHMA; BRONCHODILATOR AGENTS; BUDESONIDE; CHILD; CHILD, PRESCHOOL; CROSS-OVER STUDIES; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; INHALATION SPACERS; PITUITARY-ADRENAL SYSTEM; POLYPROPYLENES; STAINLESS STEEL;

EID: 0038359140     PISSN: 00039888     EISSN: 14682044     Source Type: Journal    
DOI: 10.1136/adc.88.6.527     Document Type: Article

References (9)

1. National Institutes of Health: National Heart Lung and Blood Institute, Global Initiative for Asthma. Global strategy for asthma management and prevention. NHLBI/WHO Workshop Report. Bethesda, MD: National Institutes of Health (publication No. 96-3659), 1995.
2. Bisgaard H. A metal aerosol holding chamber devised for young children with asthma. Eur Respir J 1995;8:856-60.
3. Bisgaard H, Anhoj J, Klug B, et al. A non-electrostatic spacer for aerosol delivery. Arch Dis Child 1995;73:226-30.
4. Barry PW, O'Callaghan C. The output of budesonide from spacer devices assessed under simulated breathing conditions. J Allergy Clin Immunol 1999;104:1205-10.
5. Agertoft L, Pedersen S. Effect of long-term treatment with inhaled budesonide on adult height in children with asthma. N Engl J Med 2000;343:1064-9.
6. Pedersen S, Fuglsang G. Urine cortisol excretion in children treated with high doses of inhaled corticosteroids: a comparison of budesonide and beclomethasone. Eur Respir J 1988;1:433-5.
7. Borgstrom L, Asking L, Beckman O, et al. Discrepancy between in vitro and in vivo dose variability for a pressurized metered dose inhaler and a dry powder inhaler. J Aerosol Med 1998;11(suppl 1):S59-64.
8. Amirav I, Newhouse MT. Aerosol therapy with valved holding chambers in young children: importance of the facemask seal. Pediatrics 2001;108:389-94.
9. Berg E. In vitro properties of pressurized metered dose inhalers with and without spacer devices. J Aerosol Med 1995;8(suppl 3):S3-10.