Detection and analysis of urinary peptides by on-line liquid chromatography and mass spectrometry: Application to patients with renal Fanconi syndrome

Clinical Science

Volumn 104, Issue 5, 2003, Pages 483-490

  Cutillas, Pedro R ^a,b,c   Norden, Anthony G W ^d   Cramer, Rainer ^a,b   Burlingame, Alma L ^a,b,e   Unwin, Robert J ^c  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^d ADDENBROOKE S HOSPITAL   (United Kingdom)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Dent's disease; Liquid chromatography; Mass spectrometry; Peptide analysis; Proteomics; Renal Fanconi syndrome; Urine

Indexed keywords

CHEMOKINE; DIAZEPAM BINDING INHIBITOR; GASTRIC INHIBITORY POLYPEPTIDE; GUANYLIN; KALLIDIN; PIGMENT EPITHELIUM DERIVED FACTOR; POLYPEPTIDE; SOMATOMEDIN B; SOMATOMEDIN C;

ANALYTIC METHOD; ARTICLE; CASE REPORT; DATA BASE; DENT DISEASE; FANCONI RENOTUBULAR SYNDROME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ION EXCHANGE CHROMATOGRAPHY; KIDNEY DISEASE; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; ONLINE SYSTEM; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN URINE LEVEL; PROTEOMICS; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; URINALYSIS;

BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CHROMATOGRAPHY, LIQUID; DATABASES, PROTEIN; FANCONI SYNDROME; HUMANS; MALE; MASS SPECTROMETRY; NANOTECHNOLOGY; PEPTIDES; PROTEOMICS; SENSITIVITY AND SPECIFICITY;

EID: 0038355369     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20020342     Document Type: Article

References (41)

1. Ibrahim, H. N., Rosenberg, M. E. and Hostetter, T. H. (2000) Proteinuria. In The Kidney: Physiology and Pathophysiology (Seldin, D. W. and Giebisch, G., eds), pp. 2269-2294, Lippincott Williams and Wilkins, Philadelphia
2. Johnson, D. W. (2000) Growth factors in progressive renal disease. Nephrology 5, 251-261
3. Norden, A. G. W., Lapsley, M., Lee, P. J. et al. (2001) Glomerular sieving and implications for renal failure in Fanconi syndrome. Kidney Int. 60, 1885
4. Norden, A. G. W., Lapsley, M., Igarashi, T. et al. (2002) Urinary megalin deficiency implicates abnormal tubular endocytic function in Fanconi syndrome. J. Am. Soc. Nephrol. 13, 125-133
5. + transporter proteins in urine. J. Am. Soc. Nephrol. 11, 2128-2132
6. Naaby-Hansen, S., Waterfield, M. D. and Cramer, R. (2001) Proteomics-post-genomic cartography to understand gene function. Trends Pharmacol. Sci. 22, 376-384
7. Mann, M., Hendrickson, R. C. and Pandey, A. (2001) Analysis of proteins and proteomes by mass spectrometry. Annu. Rev. Biochem. 70, 437-473
8. Burlingame, A., Boyd, R. and Gaskell, S. (1998) Mass Spectrometry. Anal. Chem. 70, 647R-716R
9. Gygi, S. P., Rist, B., Gerber, S. A., Turekk, F., Gelb, M. H. and Aebersold, R. (1999) Quantitative analysis of complex protein mixtures using isotope coded affinity tags. Nat. Biotechnol. 17, 994-999
10. Washburn, M., Wolters, D. and Yates, III, J. (2001) Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat. Biotechnol. 19, 242-248
11. Gharbi, S., Gaffney, P., Yang, A. et al. (2002) Evaluation of two-dimensional differential gel electrophoresis for proteomic expression analysis of a model breast cancer cell system. Mol. Cell Proteomics 1, 91-98
12. Thongboonkerd, V., McLeish, K. R., Arthur, J. M. and Klein, J. B. (2002) Proteomic analysis of normal human urinary proteins isolated by acetone precipitation or ultracentrifugation. Kidney Int. 62, 1461-1469
13. Lloyd, S., Pearce, S., Fisher, S. et al. (1996) A common molecular basis for three inherited kidney stone diseases. Nature (London) 379, 445-449
14. Wrong, O., Norden, A. and Feest, T. (1994) Dent's disease: a familial proximal renal tubular syndrome with low-molecular-weight proteinuria, hypercalciuria, nephrocalcinosis, metabolic bone disease, progressive renal failure and a marked male predominance. Q. J. Med. 87, 473-493
15. Cappiello, A., Berloni, A., Famiglini, G., Mangani, F. and Palma, P. (2001) Micro-SPE method for sample introduction in capillary HPLC. Anal. Chem. 73, 298-302
16. Shen, Y., Zhao, R., Belov, M. E. et al. (2001) Packed capillary reversed-phase liquid chromatography with high-performance electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry for proteomics. Anal. Chem. 73, 1766-1775
17. Morris, H. R., Thanai, P., Anne, D. et al. (1996) High sensitivity collisionally-activated decomposition tandem mass spectrometry on a novel quadrupole/orthogonal-acceleration time-of-flight mass spectrometer. Rapid Commun. Mass Spectrom. 10, 889-896
18. Perkins, D. N., Pappin, D. J., Creasy, D. M. and Cottrell, J. S. (1999) Probability-based protein identification by searching sequence databases using mass spectrometry data. Electrophoresis 20, 3551-3567
19. Clauser, K. R., Baker, P. R. and Burlingame, A. L. (1999) Role of accurate mass measurement (± 10 ppm) in protein identification strategies employing MS or MS/MS and database searching. Anal. Chem. 71, 2871
20. Blomback, B. and Hanson, L. A. (1979) Plasma Proteins. John Wiley and Sons Chichester
21. Richter, R., Schulz-Knappe, P., Schrader, M. et al. (1999) Composition of the peptide fraction in human blood plasma: database of circulating human peptides. J. Chromatogr. B 726, 25-35
22. Spahr, C. S., Davis, M. T., McGinley, M. D. et al. (2001) Towards defining the urinary proteome using liquid chromatography-tandem mass spectrometry I. Profiling an unfractionated tryptic digest. Proteomics 1, 93-107
23. Davis, M. T., Stahl, D. C., Swiderek, K. M. and Lee, T. D. (1994) Capillary liquid chromatography/mass spectrometry for peptide and protein characterization. Methods 6, 304-314
24. Wagner, K., Racaityte, K., Unger, K. K. et al. (2000) Protein mapping by two-dimensional high performance liquid chromatography. J. Chromatogr. A 893, 293-305
25. Dongre, A., Eng, J. and Yates, III, J. (1997) Emerging tandem-mass spectrometry techniques for the rapid identification of proteins. Trends Biotechnol. 15, 418-425
26. Crimmins, D. (1997) Strong cation-exchange high performance liquid chromatography as a versatile tool for the characterization and purification of peptides. Anal. Chim. Acta 352, 21-30
27. Kim, M., Warren, T. and Kimball, E. (1985) Purification and characterization of a low molecular weight transforming growth factor from the urine of melanoma patients. J. Biol. Chem. 260, 9237-9243
28. Meng, Q., Balcells, E., Dell'Italia, L., Durand, J. and Oparil, S. (1995) Sensitive method for quantitation of angiotensin converting enzyme (ACE) activity in tissue. Biochem. Pharmacol. 50, 1445-1450
29. Sato, K., Hirata, Y., Imai, T., Iwashima, M. and Morumo, F. (1995) Characterization of immunoreactive adrenomedullin in human plasma and urine. Life Sci. 57, 189-194
30. Walters, A. E., Myrdal, P. B., Pinsuwan, S., Manka, A. M. and Yalkowsky, S. H. (1997) Determination of melatonan II in rabbit urine using solid-phase extraction sample preparation followed by reversed-phase high-performance liquid chromatography. J. Chromatogr. B 690, 99-103
31. Sanchez, J. and Hochstrasser, D. (1999) Preparation and solubilization of body fluids for 2-D. In 2-D Proteome Analysis Protocols (Link, A. J., ed.), pp. 87-94, Humana Press, Totowa, New Jersey
32. Fierens, C., Thienpont, L. M. R., Stockl, D., Willekens, E. and Leenheer, A. (2000) Quantitative analysis of urinary C-peptide by liquid chromatography-tandem mass spectrometry with a stable isotopically labeled internal standard. J. Chromatogr. A 896, 275-278
33. Marshall, T. and Williams, K. M. (1998) High-resolution two-dimensional electrophoresis of human urinary proteins. Anal Chim. Acta 372, 147-160
34. Cutler, P., Bell, D. J., Birrell, H. C. et al. (1999) An integrated proteomic approach to studying glomerular nephrotoxicity. Electrophoresis 20, 3647-3658
35. Ostergaard, M., Wolf, H., Orntoft, T. F. and Celis, J. E. (1999) Psoriasin (S100A7): A putative urinary marker for the follow-up of patients with bladder squamous cell carcinomas. Electrophoresis 20, 349-354
36. Heine, G., Raida, M. and Forssmann, W. G. (1997) Mapping of peptides and protein fragments in human urine using liquid chromatography-mass spectrometry. J. Chromatogr. A 776, 117-124
37. Hampel, D. J., Sansome, C., Sha, M., Brodsky, S., Lawson, W. E. and Goligorsky, M. S. (2001) Toward proteomics in uroscopy: urinary protein profiles after radiocontrast medium administration. J. Am. Soc. Nephrol. 12, 1026-1035
38. Gaskell, S. J. (1997) Electrospray: principles and practice. J. Mass. Spectrom. 32, 677-688
39. Wang, S. N. and Hirschberg, R. (1999) Tubular epithelial cell activation and interstitial fibrosis. The role of glomerular ultrafiltration of growth factors in the nephrotic syndrome and diabetic nephropathy. Nephrol. Dial. Transplant. 14, 2072-2074
40. Hammerman, M. R. and Rogers, S. (1987) Distribution of IGF receptors in the plasma membrane of proximal tubular cells. Am. J. Physiol. 253, F841-F847
41. Capasso, G., Unwin, R. and Debnam, E. (2000) Hormonal influences on renal tubule transport: glucagon, somatostatin, insulin, glucocorticoid and thyroid hormones, catecholamines and selected gut-renal peptides. The Kidney (Seldin, D. W. and Giebisch, G., eds), pp. 1411-1439, Lippincott Williams and Wilkins, Philadelphia