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Volumn 5, Issue 2, 2003, Pages 160-167

Mechanisms of ischemic brain damage

Author keywords

[No Author keywords available]

Indexed keywords

ARZOXIFENE; ASPARTIC ACID; ATYPICAL ANTIPSYCHOTIC AGENT; CALCIUM; CATECHOLAMINE; CYSTEINE; ELIPRODIL; ESTRADIOL; ESTROGEN; GLUTAMIC ACID; HOMOCYSTEINE; IFENPRODIL; INDUCIBLE NITRIC OXIDE SYNTHASE; KAPPA OPIATE RECEPTOR AGONIST; N METHYL DEXTRO ASPARTIC ACID; NALMEFENE; NITRIC OXIDE; PIPERIDINE DERIVATIVE; RALOXIFENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; SEX HORMONE; SIGMA OPIATE RECEPTOR;

EID: 0038348714     PISSN: 15233782     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11886-003-0085-1     Document Type: Review
Times cited : (36)

References (76)
  • 1
    • 0037148929 scopus 로고    scopus 로고
    • Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia
    • Bernard SA, Gray TW, Buist MD, et al.: Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med 2002, 346:557-563.
    • (2002) N. Engl. J. Med. , vol.346 , pp. 557-563
    • Bernard, S.A.1    Gray, T.W.2    Buist, M.D.3
  • 2
    • 0037148926 scopus 로고    scopus 로고
    • Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest
    • The Hypothermia After Cardiac Arrest Study Group
    • The Hypothermia After Cardiac Arrest Study Group: Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med 2002, 346:549-556.
    • (2002) N. Engl. J. Med. , vol.346 , pp. 549-556
  • 3
    • 0034774096 scopus 로고    scopus 로고
    • Stroke after cardiac surgery: Short- and long-term outcomes
    • Salazaar JD, Wityk RJ, Grega MA, et al.: Stroke after cardiac surgery: short- and long-term outcomes. Ann Thorac Surg 2001, 72:1195-1201.
    • (2001) Ann. Thorac. Surg. , vol.72 , pp. 1195-1201
    • Salazaar, J.D.1    Wityk, R.J.2    Grega, M.A.3
  • 4
    • 0036193188 scopus 로고    scopus 로고
    • A review of risk factors for adverse neurologic outcome after cardiac surgery
    • Nussmeier NA: A review of risk factors for adverse neurologic outcome after cardiac surgery. J Extra Corpor Technol 2002, 34:4-10.
    • (2002) J. Extra Corpor. Technol. , vol.34 , pp. 4-10
    • Nussmeier, N.A.1
  • 5
    • 0032839765 scopus 로고    scopus 로고
    • Etiology and incidence of brain dysfunction after cardiac surgery
    • Murkin JM: Etiology and incidence of brain dysfunction after cardiac surgery. J Cardiothorac Vasc Anesth 1999, 13:12-37.
    • (1999) J. Cardiothorac. Vasc. Anesth. , vol.13 , pp. 12-37
    • Murkin, J.M.1
  • 7
    • 0035068882 scopus 로고    scopus 로고
    • Diffusion- and perfusion-weighted brain magnetic resonance imaging in patients with neurologic complications after cardiac surgery
    • Wityk RJ, Glodsborough MA, Hillis A, et al.: Diffusion- and perfusion-weighted brain magnetic resonance imaging in patients with neurologic complications after cardiac surgery. Arch Neurol 2001, 58:571-576.
    • (2001) Arch. Neurol. , vol.58 , pp. 571-576
    • Wityk, R.J.1    Glodsborough, M.A.2    Hillis, A.3
  • 8
    • 0022333159 scopus 로고
    • Selective neuronal vulnerability, morphological and molecular characteristics
    • Pulsinelli WA: Selective neuronal vulnerability, morphological and molecular characteristics. Prog Brain Res 1995, 63:29-37.
    • (1995) Prog. Brain Res. , vol.63 , pp. 29-37
    • Pulsinelli, W.A.1
  • 9
    • 0021186446 scopus 로고
    • Delayed neuronal recovery and neuronal death in rat hippocampus following severe cerebral ischemia: Possible relationship to abnormalities in neuronal processes
    • Petito CK, Pulsinelli WA: Delayed neuronal recovery and neuronal death in rat hippocampus following severe cerebral ischemia: Possible relationship to abnormalities in neuronal processes. J Cereb Blood Flow Metab 1984, 4:194-205.
    • (1984) J. Cereb. Blood Flow. Metab. , vol.4 , pp. 194-205
    • Petito, C.K.1    Pulsinelli, W.A.2
  • 10
    • 0025913062 scopus 로고
    • Temporal thresholds for neocortical infarction in rats subjected to irreversible focal cerebral ischemia
    • Kaplan B, Brint S, Tanabe J, et al.: Temporal thresholds for neocortical infarction in rats subjected to irreversible focal cerebral ischemia. Stroke 1991, 22:1032-1039.
    • (1991) Stroke , vol.22 , pp. 1032-1039
    • Kaplan, B.1    Brint, S.2    Tanabe, J.3
  • 11
    • 0019854850 scopus 로고
    • Ventricular fibrillation in the cat: A model for global cerebral ischemia
    • Todd MM, Dunlop BJ, Shapiro HM, et al.: Chadwick HC, Powell HC. Ventricular fibrillation in the cat: a model for global cerebral ischemia. Stroke 1991, 12:808-815.
    • (1991) Stroke , vol.12 , pp. 808-815
    • Todd, M.M.1    Dunlop, B.J.2    Shapiro, H.M.3    Chadwick, H.C.4    Powell, H.C.5
  • 12
    • 0021135660 scopus 로고
    • Total cerebral ischemia: Effect of alterations in arterial PCO2 on cerebral microcirculation
    • Koch KA, Jackson DL, Schmiedl M, et al.: Total cerebral ischemia: effect of alterations in arterial PCO2 on cerebral microcirculation. J Cereb Blood Flow Metab 1984, 4:343-349.
    • (1984) J. Cereb. Blood Flow. Metab. , vol.4 , pp. 343-349
    • Koch, K.A.1    Jackson, D.L.2    Schmiedl, M.3
  • 13
    • 0024850739 scopus 로고
    • Postischemic recovery rate of cerebral ATP, phosphocreatine, pH, and evoked potentials
    • Nishijima MK, Koehler RC, Hurn PD, et al.: Postischemic recovery rate of cerebral ATP, phosphocreatine, pH, and evoked potentials. Am J Physiol 1989, 257:H1860-H1870.
    • (1989) Am. J. Physiol. , vol.257
    • Nishijima, M.K.1    Koehler, R.C.2    Hurn, P.D.3
  • 14
    • 0020959273 scopus 로고
    • Local cerebral blood flow in the recovery period following complete cerebral ischemia in the rat
    • Kagstorm E, Smith M-L, Siesjo BK: Local cerebral blood flow in the recovery period following complete cerebral ischemia in the rat. J Cereb Blood Flow Metab 1983, 3:170-182.
    • (1983) J. Cereb. Blood Flow. Metab. , vol.3 , pp. 170-182
    • Kagstorm, E.1    Smith, M.-L.2    Siesjo, B.K.3
  • 15
    • 0020584664 scopus 로고
    • Regional energy balance in rat brain after transient forebrain ischemia
    • Pulsinelli WA, Duffy DE: Regional energy balance in rat brain after transient forebrain ischemia. J Neurochem 1983, 40:1500-1503.
    • (1983) J. Neurochem. , vol.40 , pp. 1500-1503
    • Pulsinelli, W.A.1    Duffy, D.E.2
  • 16
    • 0021330769 scopus 로고
    • Glutamate: A neurotransmitter in mammalian brain
    • Fonnum F: Glutamate: a neurotransmitter in mammalian brain. J Neurochem 1984, 42:1-11.
    • (1984) J. Neurochem. , vol.42 , pp. 1-11
    • Fonnum, F.1
  • 18
    • 0027513268 scopus 로고
    • Overview: Mechanisms of apoptosis
    • Cohen JJ: Overview: Mechanisms of apoptosis. Immunol Today 1993, 14:126-130.
    • (1993) Immunol. Today , vol.14 , pp. 126-130
    • Cohen, J.J.1
  • 19
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson CB: Apoptosis in the pathogenesis and treatment of disease. Science 1995, 267:1456-1462.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 20
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: An integrated view
    • Dirnagl U, Iadecola C, Moskowitz MA: Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci 1999, 22:391-397.
    • (1999) Trends Neurosci. , vol.22 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 21
    • 0028326952 scopus 로고
    • An evolutionary perspective on apoptosis
    • Vaux L, Haecker G, Strasser A: An evolutionary perspective on apoptosis. Cell 1994, 76:777-779.
    • (1994) Cell , vol.76 , pp. 777-779
    • Vaux, L.1    Haecker, G.2    Strasser, A.3
  • 23
    • 0028793257 scopus 로고
    • Necrosis and apoptosis elicited by glutamate in cerebellar granule cells: A temporal sequence depending on mitochondrial function
    • Ankarcrona M, Dypbukt JM, Bonfoco E, et al.: Necrosis and apoptosis elicited by glutamate in cerebellar granule cells: a temporal sequence depending on mitochondrial function. Neuron 1995, 15:961-973.
    • (1995) Neuron. , vol.15 , pp. 961-973
    • Ankarcrona, M.1    Dypbukt, J.M.2    Bonfoco, E.3
  • 25
    • 0014668762 scopus 로고
    • Brain lesion, obesity and other disturbances in mice treated with monosodium glutamate
    • Olney TW: Brain lesion, obesity and other disturbances in mice treated with monosodium glutamate. Science 1969, 164:719-721.
    • (1969) Science , vol.164 , pp. 719-721
    • Olney, T.W.1
  • 26
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi DW: Glutamate neurotoxicity and diseases of the nervous system. Neuron 1988, 1:299-634.
    • (1988) Neuron. , vol.1 , pp. 299-634
    • Choi, D.W.1
  • 27
    • 0021707433 scopus 로고
    • Elevation of extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis
    • Benveniste H, Drejer J, Schoushoe A, et al.: Elevation of extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem 1984, 43:1369-1374.
    • (1984) J. Neurochem. , vol.43 , pp. 1369-1374
    • Benveniste, H.1    Drejer, J.2    Schoushoe, A.3
  • 28
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • Choi DW. Excitotoxic cell death. J Neurobiol 1992, 23:1261-1276.
    • (1992) J. Neurobiol. , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 29
    • 0026717588 scopus 로고
    • Glutamate receptor channels: Novel properties and new clones
    • Sommer B, Seeburg PH: Glutamate receptor channels: novel properties and new clones. Trends Pharmacol Sci 1992, 13:291-296.
    • (1992) Trends Pharmacol. Sci. , vol.13 , pp. 291-296
    • Sommer, B.1    Seeburg, P.H.2
  • 30
    • 0025438029 scopus 로고
    • Methods of antagonizing glutamate neurotoxicity
    • Choi DW: Methods of antagonizing glutamate neurotoxicity. Cerebrovasc Brain Metab Rev 1990, 2:105-147.
    • (1990) Cerebrovasc. Brain Metab. Rev. , vol.2 , pp. 105-147
    • Choi, D.W.1
  • 31
    • 0025360957 scopus 로고
    • Ischemia in the dorsal hippocampus is associated with acute release of dopamine and norepinephrine
    • Bhardwaj A, Brannan T, Martinez-Tica J, et al.: Ischemia in the dorsal hippocampus is associated with acute release of dopamine and norepinephrine. J Neural Transm 1990, 80:195-201.
    • (1990) J. Neural. Transm. , vol.80 , pp. 195-201
    • Bhardwaj, A.1    Brannan, T.2    Martinez-Tica, J.3
  • 32
    • 0025164510 scopus 로고
    • Pentobarbital inhibits extracellular release of dopamine in the ischemic striatum
    • Bhardwaj A, Brannan T, Weinberger J: Pentobarbital inhibits extracellular release of dopamine in the ischemic striatum. J Neural Transm 1990, 82:111-117.
    • (1990) J. Neural. Transm. , vol.82 , pp. 111-117
    • Bhardwaj, A.1    Brannan, T.2    Weinberger, J.3
  • 33
    • 0023885833 scopus 로고
    • Increase in extracellular dopamine in the straitum during cerebral ischemia: A study utilizing cerebral microdialysis
    • Slivka A, Brannan TS, Weinberger J, et al.: Increase in extracellular dopamine in the straitum during cerebral ischemia: a study utilizing cerebral microdialysis. J Neurochem 1988, 50:1714-1718.
    • (1988) J. Neurochem. , vol.50 , pp. 1714-1718
    • Slivka, A.1    Brannan, T.S.2    Weinberger, J.3
  • 34
    • 0023680850 scopus 로고
    • Intraischemic extracellular release of dopamine and glutamate is associated with striatal vulnerability to ischemia
    • Globus MY-T, Busto R, Dietrich WD, et al.: Intraischemic extracellular release of dopamine and glutamate is associated with striatal vulnerability to ischemia. Neurosci Lett 1988, 91:36-40.
    • (1988) Neurosci. Lett. , vol.91 , pp. 36-40
    • Globus, M.Y.-T.1    Busto, R.2    Dietrich, W.D.3
  • 35
    • 0028120862 scopus 로고
    • Effect of etomidate on in vivo ischemia-induced dopamine release in the corpus striatum of the rat: A study using cerebral microdialysis
    • Koorn R, Brannan TS, Martinez-Tica J, et al.: Effect of etomidate on in vivo ischemia-induced dopamine release in the corpus striatum of the rat: a study using cerebral microdialysis. Anesth Analg 1994, 78:73-79.
    • (1994) Anesth. Analg. , vol.78 , pp. 73-79
    • Koorn, R.1    Brannan, T.S.2    Martinez-Tica, J.3
  • 36
    • 0027421186 scopus 로고
    • Effect of isoflurane and halothane on in vivo ischemia-induced dopamine release in the corpus striatum of the rat: A study utilizing cerebral microdialysis
    • Koorn R, Kahn RA, Martinez-Tica, et al.: Effect of isoflurane and halothane on in vivo ischemia-induced dopamine release in the corpus striatum of the rat: a study utilizing cerebral microdialysis. Anesthesiology 1993, 79:827-835.
    • (1993) Anesthesiology , vol.79 , pp. 827-835
    • Koorn, R.1    Kahn, R.A.2    Martinez-Tica, A.3
  • 37
    • 0021023811 scopus 로고
    • Nerve terminal damage in cerebral ischemia: Greater susceptibility of catecholamine nerve terminals relative to serotonin nerve terminals
    • Weinberger J, Cohen G, Nieves-Rosa J: Nerve terminal damage in cerebral ischemia: greater susceptibility of catecholamine nerve terminals relative to serotonin nerve terminals. Stroke 1983, 14:986-989.
    • (1983) Stroke , vol.14 , pp. 986-989
    • Weinberger, J.1    Cohen, G.2    Nieves-Rosa, J.3
  • 38
    • 0022004746 scopus 로고
    • Nerve terminal damage in cerebral ischemia: Protective effect of alpha-methyl-paratyrosine
    • Weinberger J, Nieves-Rosa J, Cohen G: Nerve terminal damage in cerebral ischemia: protective effect of alpha-methyl-paratyrosine. Stroke 1985, 16:864-870.
    • (1985) Stroke , vol.16 , pp. 864-870
    • Weinberger, J.1    Nieves-Rosa, J.2    Cohen, G.3
  • 39
    • 0023182260 scopus 로고
    • Subsantia nigra lesion protects against ischemic damage in the striatum
    • Globus MY-T, Ginsberg MD, Dietrich WD, et al.: Subsantia nigra lesion protects against ischemic damage in the striatum. Neurosci Lett 1987, 80:251-256.
    • (1987) Neurosci. Lett. , vol.80 , pp. 251-256
    • Globus, M.Y.-T.1    Ginsberg, M.D.2    Dietrich, W.D.3
  • 40
    • 0029062920 scopus 로고
    • Nitric oxide modulates dopamine release during global temporary cerebral ischemia
    • Kahn RA, Weinberger J, Brannan T, et al.: Nitric oxide modulates dopamine release during global temporary cerebral ischemia. Anesth Analg 1995, 80:1116-1121.
    • (1995) Anesth. Analg. , vol.80 , pp. 1116-1121
    • Kahn, R.A.1    Weinberger, J.2    Brannan, T.3
  • 41
    • 0026760948 scopus 로고
    • A novel neuronal messenger in brain: The free radical, nitric oxide
    • Dawson TM, Dawson VL, Snyder SH: A novel neuronal messenger in brain: the free radical, nitric oxide. Ann Neurol 1992, 32:297-311.
    • (1992) Ann. Neurol. , vol.32 , pp. 297-311
    • Dawson, T.M.1    Dawson, V.L.2    Snyder, S.H.3
  • 42
    • 84970313214 scopus 로고
    • Nitric oxide: Actions and pathological roles
    • Dawson TM, Dawson VL: Nitric oxide: actions and pathological roles. Neuroscientist 1995, 1:7-18.
    • (1995) Neuroscientist , vol.1 , pp. 7-18
    • Dawson, T.M.1    Dawson, V.L.2
  • 43
    • 0030988138 scopus 로고    scopus 로고
    • Nitric oxide synthase in models of focal ischemia
    • Samdani AF, Dawson TM, Dawson VL: Nitric oxide synthase in models of focal ischemia. Stroke 1997, 28:1283-1288.
    • (1997) Stroke , vol.28 , pp. 1283-1288
    • Samdani, A.F.1    Dawson, T.M.2    Dawson, V.L.3
  • 45
    • 0036218940 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase impairs early and long-term experimental stroke recovery
    • Goto S, Xue R, Sugo N, et al.: Poly(ADP-ribose) polymerase impairs early and long-term experimental stroke recovery. Stroke 2002, 33:1101-1106.
    • (2002) Stroke , vol.33 , pp. 1101-1106
    • Goto, S.1    Xue, R.2    Sugo, N.3
  • 46
    • 0028037988 scopus 로고
    • Blood flow-dependent functional recovery in a rat model of cerebral ischemia
    • Dalkara T, Morikawa H, Moskowitz MA, et al.: Blood flow-dependent functional recovery in a rat model of cerebral ischemia. Am J Physiol 1994, 267:H678-H683.
    • (1994) Am. J. Physiol. , vol.267
    • Dalkara, T.1    Morikawa, H.2    Moskowitz, M.A.3
  • 47
    • 0029780767 scopus 로고    scopus 로고
    • Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine
    • Huang Z, Huang PL, Ma J, et al.: Enlarged infarcts in endothelial nitric oxide synthase knockout mice are attenuated by nitro-L-arginine. J Cereb Blood Flow Metab 1996, 16:981-987.
    • (1996) J. Cereb. Blood Flow. Metab. , vol.16 , pp. 981-987
    • Huang, Z.1    Huang, P.L.2    Ma, J.3
  • 48
    • 0027945658 scopus 로고
    • Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase
    • Huang Z, Huang PL, Panahian N, et al.: Effects of cerebral ischemia in mice deficient in neuronal nitric oxide synthase. Science 1994, 265:1883-1885.
    • (1994) Science , vol.265 , pp. 1883-1885
    • Huang, Z.1    Huang, P.L.2    Panahian, N.3
  • 49
    • 2942572497 scopus 로고    scopus 로고
    • Role of P450 Arachidonic acid epoxygenase in ischemic preconditioning in brain
    • Edited by Krieglstein J. Stuttgart: Medpharm Scientific Publishers
    • Alkayed NJ, Goyagi T, Peng X, et al.: Role of P450 Arachidonic acid epoxygenase in ischemic preconditioning in brain. In Pharmacology of Cerebral Ischemia. Edited by Krieglstein J. Stuttgart: Medpharm Scientific Publishers; 2002.
    • (2002) Pharmacology of Cerebral Ischemia
    • Alkayed, N.J.1    Goyagi, T.2    Peng, X.3
  • 50
    • 0036277938 scopus 로고    scopus 로고
    • Neuroprotection and P450 2C11 upregulation after experimental transient ischemic attack
    • Alkayed NJ, Goyagi T, Joh HD, et al.: Neuroprotection and P450 2C11 upregulation after experimental transient ischemic attack. Stroke 2002, 33:1677-1684.
    • (2002) Stroke , vol.33 , pp. 1677-1684
    • Alkayed, N.J.1    Goyagi, T.2    Joh, H.D.3
  • 51
    • 0030965729 scopus 로고    scopus 로고
    • Role of P-450 arachidonic acid epoxygenase in the response of cerebral blood flow to glutamate in rats
    • Alkayed NJ, Birks EK, Narayanan J, et al.: Role of P-450 arachidonic acid epoxygenase in the response of cerebral blood flow to glutamate in rats. Stroke 1997, 28:1066-1072.
    • (1997) Stroke , vol.28 , pp. 1066-1072
    • Alkayed, N.J.1    Birks, E.K.2    Narayanan, J.3
  • 52
    • 33750807720 scopus 로고    scopus 로고
    • Inhibition of brain P-450 arachidonic acid epoxygenase decreases baseline cerebral blood flow
    • Alkayed NJ, Birks EK, Hudetz AG, et al.: Inhibition of brain P-450 arachidonic acid epoxygenase decreases baseline cerebral blood flow. Am J Physiol 1996, 271:H1541-H1546.
    • (1996) Am. J. Physiol. , vol.271
    • Alkayed, N.J.1    Birks, E.K.2    Hudetz, A.G.3
  • 53
    • 0031963859 scopus 로고    scopus 로고
    • Functional hyperemia in the brain: Hypothesis for astrocyte-derived vasodilator metabolites
    • Harder DR, Alkayed NJ, Lange AR, et al.: Functional hyperemia in the brain: hypothesis for astrocyte-derived vasodilator metabolites. Stroke 1998, 29:229-234.
    • (1998) Stroke , vol.29 , pp. 229-234
    • Harder, D.R.1    Alkayed, N.J.2    Lange, A.R.3
  • 54
    • 0023554153 scopus 로고
    • Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury
    • Busto R, Dietrich WD, Globus MYT, et al.: Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury. J Cereb Blood Flow Metab 1987, 7:729-738.
    • (1987) J. Cereb. Blood Flow. Metab. , vol.7 , pp. 729-738
    • Busto, R.1    Dietrich, W.D.2    Globus, M.Y.T.3
  • 55
    • 0028365406 scopus 로고
    • Hyperthermia complicates middle cerebral artery occlusion induced by an intraluminal filament
    • Zhao O, Memezawa H, Smith ML, et al.: Hyperthermia complicates middle cerebral artery occlusion induced by an intraluminal filament. Brain Res 1994, 649:253-259.
    • (1994) Brain Res. , vol.649 , pp. 253-259
    • Zhao, O.1    Memezawa, H.2    Smith, M.L.3
  • 56
    • 0025352099 scopus 로고
    • The effect of mild hyperthermia and hypothermia on brain damage following 5, 10 and 15 min of forebrain ischemia
    • Minamisawa H, Smith ML, Siesjo BK: The effect of mild hyperthermia and hypothermia on brain damage following 5, 10 and 15 min of forebrain ischemia. Ann Neurol 1990, 28:26-33.
    • (1990) Ann. Neurol. , vol.28 , pp. 26-33
    • Minamisawa, H.1    Smith, M.L.2    Siesjo, B.K.3
  • 57
    • 0023188094 scopus 로고
    • Opioid peptide levels in gerbil brain after transient ischemia: Lasting depletion of hippocampal dynorphin
    • Fried RL, Nowak TS: Opioid peptide levels in gerbil brain after transient ischemia: Lasting depletion of hippocampal dynorphin. Stroke 1987, 18:765-770.
    • (1987) Stroke , vol.18 , pp. 765-770
    • Fried, R.L.1    Nowak, T.S.2
  • 58
    • 0021267334 scopus 로고
    • Nalaxone therapy during focal cerebral ischemia evaluation in a primate model
    • Zabramski JM, Spetzler RF, Selman WR, et al.: Nalaxone therapy during focal cerebral ischemia evaluation in a primate model. Stroke 1984, 15:621-627.
    • (1984) Stroke , vol.15 , pp. 621-627
    • Zabramski, J.M.1    Spetzler, R.F.2    Selman, W.R.3
  • 59
    • 0021962769 scopus 로고
    • Protection from cerebral ischemia by U-50,488E, a specific kappa opioid analgesic agent
    • Tang AH: Protection from cerebral ischemia by U-50,488E, a specific kappa opioid analgesic agent. Life Sci 1985, 37:1475-1482.
    • (1985) Life Sci. , vol.37 , pp. 1475-1482
    • Tang, A.H.1
  • 60
    • 0027507561 scopus 로고
    • Effect of kappa-1 opioid agonist CI-977 on ischemic brain damage and cerebral blood flow after middle cerebral artery occlusion in the rat
    • Mackay KB, Kusomoto K, Graham DI, et al.: Effect of kappa-1 opioid agonist CI-977 on ischemic brain damage and cerebral blood flow after middle cerebral artery occlusion in the rat. Brain Res 1993, 629:10-18.
    • (1993) Brain Res. , vol.629 , pp. 10-18
    • Mackay, K.B.1    Kusomoto, K.2    Graham, D.I.3
  • 61
    • 0028083252 scopus 로고
    • Evaluation of delayed treatment of focal cerebral ischemia with three selective kappa-opioid agonists in cats
    • Baskin DS, Widmayer MA, Browning JL, et al.: Evaluation of delayed treatment of focal cerebral ischemia with three selective kappa-opioid agonists in cats. Stroke 1994, 25:2047-2054.
    • (1994) Stroke , vol.25 , pp. 2047-2054
    • Baskin, D.S.1    Widmayer, M.A.2    Browning, J.L.3
  • 62
    • 0033003009 scopus 로고    scopus 로고
    • Differential time-course decreases in nonselective mu-, delta-, and kappa-opioid receptors after focal cerebral ischemia in mice
    • Boutin H, Dauphin F, MacKenzie ET, et al.: Differential time-course decreases in nonselective mu-, delta-, and kappa-opioid receptors after focal cerebral ischemia in mice. Stroke 1999, 30:1271-1277.
    • (1999) Stroke , vol.30 , pp. 1271-1277
    • Boutin, H.1    Dauphin, F.2    MacKenzie, E.T.3
  • 63
    • 0022468287 scopus 로고
    • Inhibitory actions of opioid compounds on calcium fluxes and neurotransmitter release from mammalian cerebral cortical slices
    • Bradford HF, Crowder JM, White EJ: Inhibitory actions of opioid compounds on calcium fluxes and neurotransmitter release from mammalian cerebral cortical slices. Br J Pharmac 1986, 88:87-93.
    • (1986) Br. J. Pharmac. , vol.88 , pp. 87-93
    • Bradford, H.F.1    Crowder, J.M.2    White, E.J.3
  • 64
    • 0025274176 scopus 로고
    • The -opiate agonist U50488H decreases the entry of 45Ca into rat cortical synaptosomes by inhibiting N-but not L-type calcium channels
    • Xiang J-Z, Adamson P, Brammer MJ, et al.: The -opiate agonist U50488H decreases the entry of 45Ca into rat cortical synaptosomes by inhibiting N-but not L-type calcium channels. Neuropharmacology 1990, 29:439.
    • (1990) Neuropharmacology , vol.29 , pp. 439
    • Xiang, J.-Z.1    Adamson, P.2    Brammer, M.J.3
  • 65
    • 0034034434 scopus 로고    scopus 로고
    • Cervene (Nalmefene) in acute ischemic stroke. Final results of a phase III efficacy study
    • for the Cervene Stroke Study Investigators
    • Clark WM, Raps EC, Tong DC, et al.: for the Cervene Stroke Study Investigators. Cervene (Nalmefene) in acute ischemic stroke. Final results of a phase III efficacy study. Stroke 2000, 31:1234-1239.
    • (2000) Stroke , vol.31 , pp. 1234-1239
    • Clark, W.M.1    Raps, E.C.2    Tong, D.C.3
  • 66
    • 0025181385 scopus 로고
    • Pharmacological characteristics and distribution of s- and phencyclidine receptors in the animal kingdom
    • Vu TH, Weissmann AD, London ED: Pharmacological characteristics and distribution of s- and phencyclidine receptors in the animal kingdom. J Neurochem 1990, 54:598-604.
    • (1990) J. Neurochem. , vol.54 , pp. 598-604
    • Vu, T.H.1    Weissmann, A.D.2    London, E.D.3
  • 67
    • 0024281403 scopus 로고
    • Steroid binding at sigma receptors suggests a link between endocrine, nervous, and immune systems
    • Su T-P, London ED, Jaffe JH: Steroid binding at sigma receptors suggests a link between endocrine, nervous, and immune systems. Science 1988, 240:219-221.
    • (1988) Science , vol.240 , pp. 219-221
    • Su, T.-P.1    London, E.D.2    Jaffe, J.H.3
  • 68
    • 0029797712 scopus 로고    scopus 로고
    • Purification, molecular cloning, and expression of the mammalian sigma 1-binding site
    • Hanner M, Moebius FF, Flandorfer A, et al.: Purification, molecular cloning, and expression of the mammalian sigma 1-binding site. Proc Natl Acad Sci U S A 1996, 93:8072-8077.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 8072-8077
    • Hanner, M.1    Moebius, F.F.2    Flandorfer, A.3
  • 69
    • 0027853934 scopus 로고
    • Delineating biochemical and functional properties of sigma receptors: Emerging concepts
    • Su T-P: Delineating biochemical and functional properties of sigma receptors: Emerging concepts. Crit Rev Neurobiol 1993, 7:187-203.
    • (1993) Crit. Rev. Neurobiol. , vol.7 , pp. 187-203
    • Su, T.-P.1
  • 70
    • 0028232612 scopus 로고
    • Regional variation in the ratio of s1 to s2 binding in rat brain
    • Leitner ML, Hohmann AG, Patrick SL, et al.: Regional variation in the ratio of s1 to s2 binding in rat brain. Eur J Pharmacol 1994, 259:65-69.
    • (1994) Eur. J. Pharmacol. , vol.259 , pp. 65-69
    • Leitner, M.L.1    Hohmann, A.G.2    Patrick, S.L.3
  • 71
    • 0026733437 scopus 로고
    • BMY-14802 protects against ischemia-induced neuronal damage in the gerbil
    • Contreras PC, Gray NM, Ragan DM, et al.: BMY-14802 protects against ischemia-induced neuronal damage in the gerbil. Life Sci 1992, 51:1145-1149.
    • (1992) Life Sci. , vol.51 , pp. 1145-1149
    • Contreras, P.C.1    Gray, N.M.2    Ragan, D.M.3
  • 72
    • 0034930737 scopus 로고    scopus 로고
    • Neuroprotective effect of s1-receptor ligand, 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) is linked to reduced neuronal nitric oxide production
    • Goyagi T, Coto S, Bhardwaj A, et al.: Neuroprotective effect of s1-receptor ligand, 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) is linked to reduced neuronal nitric oxide production. Stroke 2001, 32:1613-1620.
    • (2001) Stroke , vol.32 , pp. 1613-1620
    • Goyagi, T.1    Coto, S.2    Bhardwaj, A.3
  • 73
    • 0033614617 scopus 로고    scopus 로고
    • Expression of nitric oxide synthase (NOS)-2 following permanent focal ischemia and the role of nitric oxide in infarct generation in male, female and NOS-2 gene deficient mice
    • Loihl AK, Asensio V, Campbell IL, et al.: Expression of nitric oxide synthase (NOS)-2 following permanent focal ischemia and the role of nitric oxide in infarct generation in male, female and NOS-2 gene deficient mice. Brain Res 1999, 830:155-164.
    • (1999) Brain Res. , vol.830 , pp. 155-164
    • Loihl, A.K.1    Asensio, V.2    Campbell, I.L.3
  • 74
    • 0033755322 scopus 로고    scopus 로고
    • Stroke Outcome in Double Mutant Antioxidant Transgenics
    • Sampei K, Mandir AS, Asano Y, et al.: Stroke Outcome in Double Mutant Antioxidant Transgenics. Stroke 2000, 31:2685-2691.
    • (2000) Stroke , vol.31 , pp. 2685-2691
    • Sampei, K.1    Mandir, A.S.2    Asano, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.