Neurotrophin-3 modifies potassium currents in isolated inner hair cells from guinea-pig cochlea

Auris Nasus Larynx

Volumn 30, Issue 2, 2003, Pages 141-145

  Kimitsuki, Takashi ^a   Nakashima, Takahiro ^a   Kawano, Hirokazu ^a   Komune, Shizuo ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Cochlea; Inner hair cell; Neurotrophin; Potassium current

Indexed keywords

NEUROTROPHIN 3;

AMPLITUDE MODULATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CELL KINETICS; CELL MEMBRANE POTENTIAL; COCHLEA; CONTROLLED STUDY; CYTOMETRY; EAR PROTECTION; GUINEA PIG; HAIR CELL; HEARING IMPAIRMENT; INNER EAR; MEMBRANE CURRENT; NONHUMAN; POTASSIUM CURRENT; VOLTAGE CLAMP;

ANIMALS; GUINEA PIGS; HAIR CELLS, INNER; MEMBRANE POTENTIALS; NEUROTROPHIN 3; POTASSIUM CHANNELS;

EID: 0038335069     PISSN: 03858146     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0385-8146(02)00116-5     Document Type: Article

References (24)

1. Lindsay R.M., Wiegand S.J., Altar C.A., Sistefano P.S. Neurotrophic factors: from molecule to man. Trends Neurosci. 17:1994;182-190.
2. Gao W.-Q. Therapeutic potential of neurotrophins for treatment of hearing loss. Mol. Neurobiol. 17:1998;17-31.
3. Fritzsch B., Pirvola U., Ylikoski J. Making and breaking the innervation of the ear: Neurotrophic support during ear development and its clinical implications. Cell Tissue Res. 295:1999;369-382.
4. Farinãs I., Jones K.R., Tessarollo L., Vigers A.J., Huang E., Kirstein M., et al. Spatial shaping of cochlear innervation by temporally regulated neurotrophin expression. J. Neurosci. 21:2001;6170-6180.
5. Pirvola U., Ylikoski J., Palgi J., Lehtonen E., Arumae U., Saarma M. Brain-derived neurotrophic factor and neurotrophin 3 mRNAs in the peripheral target fields of developing inner ear gabglia. Proc. Natl. Acad. Sci. USA. 89:1992;9915-9919.
6. Pirvola U., Arumae U., Moshnyakov M., Palgi J., Saarma M., Ylikoski J. Coordinated expression and function of neurotrophins and their receptors in the rat inner ear during target innervation. Hear. Res. 75:1994;131-144.
7. Lohof A.M., Ip N.Y., Poo M.M. Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF. Nature. 363:1993;350-353.
8. Numakawa T., Takei N., Yamagishi S., Sakaki N., Hatanaka H. Neurotrophin-elicited short-term glutamate release from cultured cerebellar granule neurons. Brain Res. 842:1999;431-438.
9. He D.Z.Z., Zheng R., Edge R., Dallos P. Isolation of cochlear inner hair cells. Hear. Res. 145:2000;156-160.
10. Holm N.R., Christophersen P., Olesen S.P., Gammeltoft S. Activation of calcium-dependent potassium channels in rat brain neurons by neurotrophin-3 and nerve growth factor. Proc. Natl. Acad. Sci. USA. 94:1997;1002-1006.
11. Jia M., Li M., Liu X.-W., Jiang H., Nelson P.G., Guroff G. Voltage-sensitive calcium currents are acutely increased by nerve growth factor in PC12 cells. J. Neurophysiol. 82:1999;2847-2852.
12. 2+ chelators. Pflüg. Arch. 430:1995;365-373.
13. k,f, in guinea-pig inner hair cells is regulated by protein kinase A. Neurosci. Lett. 263:1999;145-148.
14. Hudspeth A.J., Lewis R.S. Kinetic analysis of voltage-and ion-dependent conductances in saccular hair cells of the bull-frog, Rana Catesbeiana. J. Physiol. 400:1988;237-274.
15. Jiménez C., Giréldez F., Represa J., García-Díaz J.F. Calcium currents in dissociated cochlear neurons from the chick embryo and their modification by neurotrophin-3. Neuroscience. 77:1997;673-682.
16. 2+ channels in adult frog sympathetic ganglion B cells by nerve growth factor in vitro and in vivo. J. Neurophysiol. 78:1997;3359-3370.
17. Lesser S.S., Sherwood N.T., Lo D.C. Neurotrophins differentially regulate voltage-gated ion channels. Mol. Cell. Neurosci. 10:1997;173-183.
18. 2+ elevation in hippocampal neurons. Neuroreport. 4:1993;1303-1306.
19. Li Y.-X., Zhang Y., Lester H.A., Schuman E.M., Davidson N. Enhancement of neurotransmitter release induced by brain-derived neurotrophic factor in cultured hippocampal neurons. J. Neurosci. 18:1998;10231-10240.
20. Stoop R., Poo M.-M. Synaptic modulation by neurotrophic factors: differential and synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor. J. Neurosci. 6:1996;3256-3264.
21. Parsons T.D., Lenzi D., Almers W., Roberts W.M. Calcium-triggered exocytosis and endocytosis in an isolated presynaptic cell: capacitance measurements in saccular hair cells. Neuron. 13:1994;875-883.
22. Mosers T., Beutner D. Kinetics of exocytosis and endocytosis at the cochlear inner hair cell afferent synapse of the mouse. PNAS. 97:2000;883-888.
23. Spassova M., Eisen M.D., Saunders J.C., Parsons T.D. Chick cochlear hair cell exocytosis mediated by dihydropyridine-sensitive calcium channels. J. Physiol. 535.3:2001;689-696.
24. Oestreicher E., Knipper M., Arnold A., Zenner H.P. Neurotrophin 3 potentiates glutamatergic responses of IHC afferents in the cochlea in vivo. Eur. J. Neurosci. 12:(5):2000;1584-1590.