Assessment of antimicrobial activity of hydrophilic betaines in osmotically stressed bacteria

Antonie van Leeuwenhoek, International Journal of General and Molecular Microbiology

Volumn 83, Issue 2, 2003, Pages 175-181

  Peddie, Barbara A ^a   Wood, Jacqueline E ^b   Lever, Michael ^b   Happer, D Alan R ^c   de Zwart, Frederick ^b   Chambers, Stephen T ^b  

^a CHRISTCHURCH HOSPITAL   (New Zealand)

^b CANTERBURY HEALTH LABORATORIES   (New Zealand)

^c UNIVERSITY OF CANTERBURY   (New Zealand)

Author keywords

4 Methylthiazolium betaine; Heterocyclic betaines; Trigonelline

Indexed keywords

1 METHYLIMADAZOLIUM BETAINE; 1,2 DIMETHYLIMADAZOLIUM BETAINE; 3 CARBOXYMETHYLBENZOTHIAZOLIUM; 3 CYANOPYRIDINE BETAINE; 4 DIMETHYLPYRIDINIUM BETAINE; 4 METHYLTHIAZOLIUM BETAINE; ANTIINFECTIVE AGENT; AROMATIC COMPOUND; BETAINE DERIVATIVE; NICOTINAMIDE BETAINE; QUINUCLIDINE BETAINE; TRIGONELLINE; UNCLASSIFIED DRUG; UREA;

ANTIMICROBIAL ACTIVITY; BACTERIUM;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM CULTURE; CELL MEMBRANE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG SYNTHESIS; ESCHERICHIA COLI; ESCHERICHIA COLI K 12; GRAM NEGATIVE BACTERIUM; HYDROPHILICITY; NONHUMAN; OSMOTIC PRESSURE; OSMOTIC STRESS; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ALKALOIDS; ANIMALS; BETAINE; CELL LINE; DOGS; ESCHERICHIA COLI; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; OSMOLAR CONCENTRATION; OSMOTIC PRESSURE; STAPHYLOCOCCUS AUREUS; UREA;

BACTERIA (MICROORGANISMS); ESCHERICHIA; ESCHERICHIA COLI K12; NEGIBACTERIA;

EID: 0038324270     PISSN: 00036072     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1023305326164     Document Type: Article

References (29)

1. Abdel-Ghany Y.S., Ihnat M.A., Miller D.D., Kunin C.M. and Tong H.H. 1993. Structure-activity relationship of glycine betaine analogues on osmotolerance of enteric bacteria. J. Med. Chem. 36: 784-789.
2. Amin U.S., Lash T.D. and Wilkinson B.J. 1995. Proline betaine is a highly effective osmoprotectant for Staphylococcus aureus. Arch. Microbiol. 163: 138-142.
3. Bochner B.R. and Savageau M.A. 1997. Generalized indicator plates for genetic, metabolic, and taxonomic studies with micro-organisms. Appl. Environ. Microbiol. 33: 434-444.
4. Chambers S.T. and Kunin C.M. 1985. The osmoprotective properties of urine for bacteria: the protective effect of betaine and human urine against tow pH and high concentrations of electrolytes, sugars and urea. J. Infect. Dis. 152: 1308-131.
5. Csonka L.N. 1989. Physiological and genetic responses of bacteria to osmotic stress. Microbiol. Rev. 53: 121-147.
6. Davis B.D., Dulbecco R., Eisen H.W. and Wood W.D. 1973. Microbiology. 2nd edn. Harper Row, Maryland, (p 95).
7. Dunlap V.J. and Csonka L.N. 1985. Regulation of the osmotically stimulated transport of proline and glycinebetaine in Salmonella typhimurium. J. Bacteriol. 163: 296-304.
8. Galinski E.A. and Trüper H.G. 1994. Microbial behaviour in salt-stressed ecosystems. FEMS Microbiol. Rev. 15: 95-108.
9. Gilles R. 1997. "Compensatory" organic osmolytes in high osmolarity and dehydration stresses: history and perspectives. Comp. Biochem. Physiol. 117A: 279-290.
10. Landfald B. and Strøm A.R. 1986. Choline-glycine betaine pathway confers a high level osmotic tolerance in Escherichia coli. J. Bacteriol. 165: 849-855.
11. Larsen P.I., Sydnes L.K., Landfald L.K. and Strøm A.R. 1987. Osmoregulation in Escherichia coli by accumulation of organic osmolytes: betaines, glutamic acid, and trehalose. Arch. Microbiol. 147: 1-7.
12. Lever M., Sizeland P.C.B., Bason, Hayman C.M. and Chambers S.T. 1994. Glycine betaine and proline betaine in human blood and urine. Biochim. Biophys. Acta 1200: 259-264.
13. Nakanishi T., Turner R.J. and Burg M.B. 1990. Osmoregulation of betaine transport in mammalian renal medullary cells. Am. J. Physiol. 258: F1061-F1067.
14. Neihardt F.C., Bloch P.L. and Smith D.F. 1974. Culture medium for enterobacteria. J. Bacteriol. 119: 736-747.
15. Pattee P.A. and Neveln D.S. 1975. Transformation analysis of three linkage groups in Staphylococcus aureus. J. Bacteriol. 124: 201-211.
16. Peddie B.A. and Chambers S.T. 1993. Effects of betaines and urine on the antibacterial activity of aminoglycosides. J. Antimicrob. Chemotherapy 31: 481-488.
17. Peddie B.A., Lever M., Hayman C.M., Randall K. and Chambers S.T. 1994. Relationship between osmoprotection and the structure and intracellular accumulation of betaines by Escherichia coli. FEMS Microbiol. Lett. 120: 125-132.
18. Peddie B.A., Wong-She J., Randall K., Lever M. and Chambers S.T. 1998. Osmoprotective properties and accumulation of betaine analogues by Staphylococcus aureus. FEMS Microbiol. Lett. 160: 25-30.
19. Perroud B. and Le Rudulier D. 1985. Glycine betaine transport in Escherichia coli: osmotic modulation. J. Bacteriol. 161: 393-401.
20. Randall K. 1997. What makes betaines effective compatible solutes?, University of Otago, Dunedin, New Zealand.
21. Randall K., Lever M., Happer D.A.R., Peddie B.A. and Chambers S.T. 1998. Protective effects of homarine, trigonelline and isomeric pyridinium betaines. J. Biochem. Mol. Biol. Biophys. 1: 205-212.
22. Randall K., Lever M., Peddie B.A. and Chambers S.T. 1995. Competitive accumulation of betaines by Escherichia coli K-12 and derivative strains lacking betaine porters. Biochim. Biophys. Acta 1245: 116-120.
23. Randall K., Lever M., Peddie B.A. and Chambers S.T. 1996a. Accumulation of natural and synthetic betaines by a mammalian renal cell line. Biochem. Cell Biol. 74: 283-287.
24. Randall K., Lever M., Peddie B.A. and Chambers S.T. 1996b. Natural and synthetic betaines counter the effects of high NaCl and urea concentrations. Biochim. Biophys. Acta 1291: 189-194.
25. Severin J., Wohlfarth A. and Galinski E.A. 1992. The predominant role of recently discovered tetrahydropyrimidines for the osmoadaptation of halophilic eubacteria. J. Gen. Microbiol. 138: 1629-1638.
26. Timasheff S.N. 1993. The control of protein stability and association by weak interactions with water: how do solvents affect these processes? Ann. Rev. Biophys. Biomol. Struct. 22: 67-9725.
27. Wood J.M. and Zadworny G. 1979. Characterization of an inducible porter required for L-proline catabolism by Escherichia coli K12. Can. J. Biochem. 57: 1191-1199.
28. Yancey P.H., Clark M.E., Hand S.C., Bowlus R.D. and Somero G.N. 1982. Living with water stress: evolution of osmolyte systems. Science 217: 1214-1222.
29. Yeo A. 1998. Molecular biology of salt tolerance in the context of whole-plant physiology. J. Exptl Bot. 49: 915-929.