The herpes simplex virus type 1 DNA polymerase processivity factor increases fidelity without altering pre-steady-state rate constants for polymerization or excision

Journal of Biological Chemistry

Volumn 278, Issue 11, 2003, Pages 8996-9004

  Chaudhuri, Murari ^b   Song, Liping ^b   Parris, Deborah S ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; DNA; ENZYMES; RATE CONSTANTS; VIRUSES;

ENZYME DISSOCIATION;

BIOCHEMISTRY;

DNA POLYMERASE; PROTEIN UL42; UNCLASSIFIED DRUG; VIRUS PROTEIN; DNA; DNA DIRECTED DNA POLYMERASE; DNA POLYMERASE, SIMPLEXVIRUS; EXODEOXYRIBONUCLEASE; PYRIMIDINE NUCLEOTIDE; THYMIDINE 5'-TRIPHOSPHATE; THYMIDINE TRIPHOSPHATE;

ADDITION REACTION; ARTICLE; COMPLEX FORMATION; DISSOCIATION CONSTANT; DNA BINDING; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME MECHANISM; EXCISION; HERPES SIMPLEX VIRUS 1; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; STEADY STATE; ANIMAL; BASE MISPAIRING; BINDING SITE; BIOSYNTHESIS; CELL LINE; CHEMISTRY; DOSE RESPONSE; INSECT; KINETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; TEMPERATURE; TIME;

DNA VIRUSES; HERPES; HUMAN HERPESVIRUS 1;

ANIMALS; BASE PAIR MISMATCH; BASE SEQUENCE; BINDING SITES; CATALYTIC DOMAIN; CELL LINE; DNA; DNA-DIRECTED DNA POLYMERASE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXODEOXYRIBONUCLEASES; INSECTS; KINETICS; MOLECULAR SEQUENCE DATA; TEMPERATURE; THYMINE NUCLEOTIDES; TIME FACTORS; VIRAL PROTEINS;

EID: 0038322040     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M210023200     Document Type: Article

References (50)

1. Crute, J. J., and Lehman, I. R. (1989) J. Biol. Chem. 264, 19266-19270
2. Gallo, M. L., Jackwood, D. H., Murphy, M., Marsden, H. S., and Parris, D. S. (1988) J. Virol. 62, 2874-2883
3. Gottlieb, J., Marcy, A. I., Coen, D. M., and Challberg, M. D. (1990) J. Virol. 64, 5976-5987
4. Parris, D. S., Cross, A., Haarr, L., Orr, A., Frame, M. C., McGeoch, D. J., and Marsden, H. S. (1988) J. Virol. 62, 818-825
5. Dorsky, D. I., and Crumpacker, C. S. (1988) J. Virol. 62, 3224-3232
6. Haffey, M. L., Stevens, J. T., Terry, B. J., Dorsky, D. I., Crumpacker, C. S., Wietstock, S. M., Ruyechan, W. T., and Field, A. K. (1988) J. Virol. 62, 4493-4498
7. Marcy, A. I., Olivo, P. D., Challberg, M. D., and Coen, D. M. (1990) Nucleic Acids Res. 18, 1207-1215
8. Hernandez, T. R., and Lehman, I. R. (1990) J. Biol. Chem. 265, 11227-11232
9. Jofre, J. T., Schaffer, P. A., and Parris, D. S. (1977) J. Virol. 23, 833-836
10. Wu, C. A., Nelson, J. J., McGeoch, D. J., and Challberg, M. D. (1988) J. Virol. 62, 435-443
11. Stow, N. D. (1992) J. Gen. Virol. 73, 313-321
12. Johnson, P. A., Best, M. G., Friedmann, T., and Parris, D. S. (1991) J. Virol. 65, 700-710
13. Marchetti, M. E., Smith, C. A., and Schaffer, P. A. (1988) J. Virol. 62, 715-721
14. Kelman, Z., and O'Donnell, M. (1995) Nucleic Acids Res. 23, 3613-3620
15. Knopf, K.-W. (1979) Eur. J. Biochem. 98, 231-244
16. Hwang, Y. T., Liu, B.-Y., Coen, D. M., and Hwang, C. B. C. (1997) J. Virol. 71, 7791-7798
17. Hwang, Y. T., Liu, B.-Y., Hong, C.-Y., Shillitoe, E. J., and Hwang, C. B. C. (1999) J. Virol. 73, 5326-5332
18. Kühn, F. J. P., and Knopf, C. W. (1996) J. Biol. Chem. 271, 29245-29254
19. Mozzherin, D. J., McConnell, M., Jasko, M. V., Krayevsky, A. A., Tan, C.-K., Downey, K. M., and Fisher, P. A. (1996) J. Biol. Chem. 271, 31711-31717
20. Daube, S. S., Tomer, G., and Livneh, Z. (2000) Biochemistry 39, 348-355
21. Kunkel, T. A., Patel, S. S., and Johnson, K. A. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 6830-6834
22. Chaudhuri, M., and Parris, D. S. (2002) J. Virol. 76, 10270-10281
23. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd Ed., pp. 11.31-11.32, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
24. Johnson, K. A. (1986) Methods Enzymol. 134, 677-705
25. Hart, G. J., and Boehme, R. E. (1992) FEBS Lett. 30, 97-100
26. Berthommé, H., Monahan, S. J., Parris, D. S., Jacquemont, B., and Epstein, A. L. (1995) J. Virol. 69, 2811-2818
27. Patel, S. S., Wong, I., and Johnson, K. A. (1991) Biochemistry 30, 511-525
28. Ahn, J., Werneburg, B. G., and Tsai, M.-D. (1997) Biochemistry 36, 1100-1107
29. Capson, T. L., Peliska, J. A., Kaboord, B. F., Frey, M. W., Lively, C., Dahlberg, M., and Benkovic, S. J. (1992) Biochemistry 31, 10984-10994
30. Donlin, M. J., Patel, S. S., and Johnson, K. A. (1991) Biochemistry 30, 536-546
31. Johnson, A. A., and Johnson, K. A. (2001) J. Biol. Chem. 276, 38090-38096
32. Gottlieb, J., and Challberg, M. D. (1994) J. Virol. 68, 4937-4945
33. Weisshart, K., Chow, C. S., and Coen, D. M. (1999) J. Virol. 73, 55-66
34. Kati, W. M., Johnson, K. A., Jerva, L. F., and Anderson, K. S. (1992) J. Biol. Chem. 267, 25988-25997
35. Benkovic, S. J., and Schray, K. J. (1971) in The Enzymes (Boyer, P. D., ed) 3rd Ed., Vol. 8, pp. 201-238, Academic Press, New York
36. Mizrahi, V., Henrie, R. N., Marlier, J. F., Johnson, K. A., and Benkovic, S. J. (1985) Biochemistry 24, 4010-4018
37. Herschlag, D., Piccirilli, J. A., and Cech, T. R. (1991) Biochemistry 30, 4844-4854
38. Kuchta, R. D., Mizrahi, V., Benkovic, P. A., Johnson, K. A., and Benkovic, S. J. (1987) Biochemistry 26, 8410-8417
39. Dahlberg, M. E., and Benkovic, S. J. (1991) Biochemistry 30, 4835-4843
40. Einolf, H. J., and Guengerich, F. P. (2000) J. Biol. Chem. 275, 16316-16322
41. Werneburg, B. G., Ahn, J., Zhong, X., Hondal, R. J., Kraynov, V. S., and Tsai, M.-D. (1996) Biochemistry 35, 7041-7050
42. Joyce, C. M., and Steitz, T. A. (1994) Annu. Rev. Biochem. 63, 777-822
43. Kumar, J. K., Tabor, S., and Richardson, C. C. (2001) J. Biol. Chem. 276, 34905-34912
44. Ng, L., McConnell, M., Tan, C.-K., Downey, K. M., and Fisher, P. A. (1993) J. Biol. Chem. 268, 13571-13576
45. Johnson, A. A., Tsai, Y.-C., Graves, S. W., and Johnson, K. A. (2000) Biochemistry 39, 1702-1708
46. Kaboord, B. F., and Benkovic, S. J. (1996) Biochemistry 35, 1084-1092
47. Monahan, S. J., Grinstead, L. A., Olivieri, W., and Parris, D. S. (1998) Virology 241, 122-130
48. Goodrich, L. D., Schaffer, P. A., Dorsky, D. I., Crumpacker, C. S., and Parris, D. S. (1990) J. Virol. 64, 5738-5749
49. Wu, P., Nossal, N., and Benkovic, S. J. (1998) Biochemistry 37, 14748-14755
50. Wong, I., Patel, S. S., and Johnson, K. A. (1991) Biochemistry 30, 526-537