메뉴 건너뛰기




Volumn 12, Issue 2, 2003, Pages 94-97

Meeting unmet needs in patients with sepsis: The role of drotrecogin alfa (activated)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; DROTRECOGIN; PROTEIN C; RECOMBINANT PROTEIN;

EID: 0038283073     PISSN: 10623264     EISSN: None     Source Type: Journal    
DOI: 10.4037/ajcc2003.12.2.94     Document Type: Editorial
Times cited : (2)

References (30)
  • 3
    • 34748898595 scopus 로고    scopus 로고
    • The Leapfrog Group for Patient Safety, November, Available at:, Accessed December 20
    • The Leapfrog Group for Patient Safety. ICU physician staffing [fact sheet]. November 2000. Available at: http://www.leapfroggroup.org/FactSheets. htm. Accessed December 20, 2002.
    • (2000) ICU physician staffing [fact sheet]
  • 4
  • 5
    • 0033590515 scopus 로고    scopus 로고
    • Treating patients with severe sepsis
    • Wheeler AP, Bernard GR. Treating patients with severe sepsis. N Engl J Med. 1999;340:207-214.
    • (1999) N Engl J Med , vol.340 , pp. 207-214
    • Wheeler, A.P.1    Bernard, G.R.2
  • 6
    • 0343893748 scopus 로고    scopus 로고
    • Ventilation with lower tidal as compared with traditional tidal for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med. 2000;342:1301-1308
    • Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med. 2000;342:1301-1308.
  • 7
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
    • Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001;29:1303-1310.
    • (2001) Crit Care Med , vol.29 , pp. 1303-1310
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Lidicker, J.3    Clermont, G.4    Carcillo, J.5    Pinsky, M.R.6
  • 8
    • 0030746482 scopus 로고    scopus 로고
    • Anti-inflammatory therapies to treat sepsis and septic shock: A reassessment
    • Zeni F, Freeman B, Natanson C. Anti-inflammatory therapies to treat sepsis and septic shock: a reassessment. Crit Care Med. 1997;25:1095-1100.
    • (1997) Crit Care Med , vol.25 , pp. 1095-1100
    • Zeni, F.1    Freeman, B.2    Natanson, C.3
  • 9
    • 0030854780 scopus 로고    scopus 로고
    • Epidemiology of sepsis syndrome in 8 academic medical centers. Academic Medical Center Consortium Sepsis Project Working Group
    • Sands KE, Bates DW, Lanken PN, et al. Epidemiology of sepsis syndrome in 8 academic medical centers. Academic Medical Center Consortium Sepsis Project Working Group. JAMA. 1997;278:234-240.
    • (1997) JAMA , vol.278 , pp. 234-240
    • Sands, K.E.1    Bates, D.W.2    Lanken, P.N.3
  • 10
    • 0029147346 scopus 로고
    • Incidence, risk factors, and outcome of severe sepsis and septic shock in adults: A multicenter prospective study in intensive care units. French ICU Group for Severe Sepsis
    • Brun-Buisson C, Doyon F, Carlet J, et al. Incidence, risk factors, and outcome of severe sepsis and septic shock in adults: a multicenter prospective study in intensive care units. French ICU Group for Severe Sepsis. JAMA. 1995;274:968-974.
    • (1995) JAMA , vol.274 , pp. 968-974
    • Brun-Buisson, C.1    Doyon, F.2    Carlet, J.3
  • 11
    • 0034948270 scopus 로고    scopus 로고
    • Severe sepsis: National estimates
    • Wenzel RP, Edmond MB. Severe sepsis: national estimates. Crit Care Med. 2001;29:1472-1474.
    • (2001) Crit Care Med , vol.29 , pp. 1472-1474
    • Wenzel, R.P.1    Edmond, M.B.2
  • 13
    • 0031035860 scopus 로고    scopus 로고
    • I'm sorry to say that I don't like you . .
    • Vincent JL. Dear SIRS, I'm sorry to say that I don't like you . . . Crit Care Med. 1997;25:372-374.
    • (1997) Crit Care Med , vol.25 , pp. 372-374
    • Vincent, J.L.1    Dear, S.I.R.S.2
  • 14
    • 0033054742 scopus 로고    scopus 로고
    • Clinical trials for severe sepsis: Past failures, and future hopes
    • Opal SM, Cross AS. Clinical trials for severe sepsis: past failures, and future hopes. Infect Dis Clin North Am. 1999;13:285-297.
    • (1999) Infect Dis Clin North Am , vol.13 , pp. 285-297
    • Opal, S.M.1    Cross, A.S.2
  • 15
    • 0033586986 scopus 로고    scopus 로고
    • Vascular bed-specific hemostasis and hypercoagulable states
    • Rosenberg RD, Aird WC. Vascular bed-specific hemostasis and hypercoagulable states. N Engl J Med. 1999;340:1555-1564.
    • (1999) N Engl J Med , vol.340 , pp. 1555-1564
    • Rosenberg, R.D.1    Aird, W.C.2
  • 16
    • 0031945092 scopus 로고    scopus 로고
    • Increased circulating thrombomodulin in children with septic shock
    • Krafte-Jacobs B, Brilli R. Increased circulating thrombomodulin in children with septic shock. Crit Care Med. 1998;26:933-938.
    • (1998) Crit Care Med , vol.26 , pp. 933-938
    • Krafte-Jacobs, B.1    Brilli, R.2
  • 17
    • 0029800805 scopus 로고    scopus 로고
    • Endothelial cell activity varies in patients at risk for the adult respiratory distress syndrome
    • Moss M, Gillespie MK, Ackerson L, Moore FA, Moore EE, Parsons PE. Endothelial cell activity varies in patients at risk for the adult respiratory distress syndrome. Crit Care Med. 1996;24:1782-1786.
    • (1996) Crit Care Med , vol.24 , pp. 1782-1786
    • Moss, M.1    Gillespie, M.K.2    Ackerson, L.3    Moore, F.A.4    Moore, E.E.5    Parsons, P.E.6
  • 18
    • 0035833529 scopus 로고    scopus 로고
    • Dysfunction of endothelial protein C activation in severe meningococcal sepsis
    • Faust SN, Levin M, Harrison OB, et al. Dysfunction of endothelial protein C activation in severe meningococcal sepsis. N Engl J Med. 2001;345:408-416.
    • (2001) N Engl J Med , vol.345 , pp. 408-416
    • Faust, S.N.1    Levin, M.2    Harrison, O.B.3
  • 19
    • 0034834039 scopus 로고    scopus 로고
    • Low levels of protein C are associated with poor outcome in severe sepsis
    • Yan SB, Helterbrand JD, Hartman DL, Wright TJ, Bernard GR. Low levels of protein C are associated with poor outcome in severe sepsis. Chest. 2001;120:915-922.
    • (2001) Chest , vol.120 , pp. 915-922
    • Yan, S.B.1    Helterbrand, J.D.2    Hartman, D.L.3    Wright, T.J.4    Bernard, G.R.5
  • 20
    • 0034912330 scopus 로고    scopus 로고
    • Role of coagulation inhibitors in inflammation
    • Esmon CT. Role of coagulation inhibitors in inflammation. Thromb Haemost. 2001;86:51-56.
    • (2001) Thromb Haemost , vol.86 , pp. 51-56
    • Esmon, C.T.1
  • 21
    • 0033638851 scopus 로고    scopus 로고
    • 13th Annual Congress of the European Society of Intensive Care Medicine, Rome, Italy, 1-4 October 2000
    • Smith D. 13th Annual Congress of the European Society of Intensive Care Medicine, Rome, Italy, 1-4 October 2000. Crit Care. 2000;4:347-351.
    • (2000) Crit Care , vol.4 , pp. 347-351
    • Smith, D.1
  • 23
    • 0033815369 scopus 로고    scopus 로고
    • The protein C pathway
    • Esmon C. The protein C pathway. Crit Care Med. 2000;28(9 suppl):S44-S48.
    • (2000) Crit Care Med , vol.28 , Issue.9 SUPPL.
    • Esmon, C.1
  • 24
    • 0038621982 scopus 로고    scopus 로고
    • Advances in the understanding of clinical manifestations and therapy of severe sepsis: An update for critical care nurses
    • Ely EW, Kleinpell RM, Goyette RE. Advances in the understanding of clinical manifestations and therapy of severe sepsis: an update for critical care nurses. Am J Crit Care. 2003;12:120-135.
    • (2003) Am J Crit Care , vol.12 , pp. 120-135
    • Ely, E.W.1    Kleinpell, R.M.2    Goyette, R.E.3
  • 26
    • 0037179680 scopus 로고    scopus 로고
    • An economic evaluation of activated protein C treatment for severe sepsis
    • Manns BJ, Lee H, Doig CJ, Johnson D, Donaldson C. An economic evaluation of activated protein C treatment for severe sepsis. N Engl J Med. 2002;347:993-1000.
    • (2002) N Engl J Med , vol.347 , pp. 993-1000
    • Manns, B.J.1    Lee, H.2    Doig, C.J.3    Johnson, D.4    Donaldson, C.5
  • 27
    • 0037253093 scopus 로고    scopus 로고
    • Cost-effectiveness of drotrecogin alfa (activated) in the treatment of severe sepsis
    • Angus DC, Linde-Zwirble WT, Clermont G, et al. Cost-effectiveness of drotrecogin alfa (activated) in the treatment of severe sepsis. Crit Care Med. 2003;31:1-11.
    • (2003) Crit Care Med , vol.31 , pp. 1-11
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Clermont, G.3
  • 28
    • 0029011305 scopus 로고
    • A cost-effectiveness model of thrombolytic therapy for acute myocardial infarction
    • Kalish SC, Gurwitz JH, Krumholz HM, Avorn J. A cost-effectiveness model of thrombolytic therapy for acute myocardial infarction. J Gen Intern Med. 1995;10:321-330.
    • (1995) J Gen Intern Med , vol.10 , pp. 321-330
    • Kalish, S.C.1    Gurwitz, J.H.2    Krumholz, H.M.3    Avorn, J.4
  • 29
    • 0031028592 scopus 로고    scopus 로고
    • Cost-effectiveness of implantable cardioverter defibrillators relative to amiodarone for prevention of sudden cardiac death
    • Owens DK, Sanders GD, Harris RA, et al. Cost-effectiveness of implantable cardioverter defibrillators relative to amiodarone for prevention of sudden cardiac death. Ann Intern Med. 1997;126:1-12.
    • (1997) Ann Intern Med , vol.126 , pp. 1-12
    • Owens, D.K.1    Sanders, G.D.2    Harris, R.A.3
  • 30
    • 0036939629 scopus 로고    scopus 로고
    • Selecting patients with severe sepsis for drotrecogin alfa (activated) therapy
    • Sollet JP, Garber GE. Selecting patients with severe sepsis for drotrecogin alfa (activated) therapy. Am J Surg. 2002;184:S11-S18.
    • (2002) Am J Surg , vol.184
    • Sollet, J.P.1    Garber, G.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.