Analysis of immunodominance among minor histocompatibility antigens in allogeneic hematopoietic stem cell transplantation

Bone Marrow Transplantation

Volumn 31, Issue 10, 2003, Pages 865-875

  Mori, S ^a   El Baki, H ^a   Mullen, C A ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

Graft versus host disease; Minor histocompatibility antigen

Indexed keywords

EPITOPE; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; MINOR HISTOCOMPATIBILITY ANTIGEN;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ALLOIMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PURIFICATION; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DONOR; FEMALE; GRAFT VERSUS HOST REACTION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HLA MATCHING; HOST CELL; IMMUNOBIOLOGY; IMMUNOMODULATION; IMMUNOTHERAPY; MISMATCH REPAIR; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; BONE MARROW TRANSPLANTATION; CYTOTOXICITY, IMMUNOLOGIC; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLYCOSYLTRANSFERASES; GRAFT VS HOST DISEASE; IMMUNODOMINANT EPITOPES; IMMUNOSUPPRESSION; ISCHEMIC PRECONDITIONING; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MINOR HISTOCOMPATIBILITY ANTIGENS; PEPTIDE FRAGMENTS; STEM CELL TRANSPLANTATION; T-LYMPHOCYTES; TRANSPLANTATION, HOMOLOGOUS; WHOLE-BODY IRRADIATION;

EID: 0038282773     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1704021     Document Type: Article

References (25)

1. Green MC, Witham BA. Handbook on Genetically Standardized Jax Mice. 4th edn. Jackson Laboratory: Bar Harbor, ME, 1991.
2. Korngold R, Sprent J. Variable capacity of L3T4+ T cells to cause lethal graft-versus-host disease across minor histocompatibility barriers in mice. J Exp Med 1987; 165: 1552-1564.
3. Eden PA, Christianson GJ, Fontaine P et al. Biochemical and immunogenetic analysis of an immunodominant peptide (B6dom1) encoded by the classical H7 minor histocompatibility locus. J. Immunol. 1999; 162: 4502-4510.
4. Zuberi AR, Christianson GJ, Mendoza LM et al. Positional cloning and molecular characterization of an immunodominant cytotoxic determinant of the mouse H3 minor histocompatibility complex. Immunity 1998; 9: 687-698.
5. Mendoza LM, Paz P, Zuberi A et al. Minors held by majors: the H13 minor histocompatibility locus defined as a peptide/MHC class I complex. Immunity 1997; 7: 461-472.
6. Chen W, Anton LC, Bennink JR, Yewdell JW. Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses. Immunity 2000; 12: 83-93.
7. Pion S, Fontaine P, Desaulniers M et al. On the mechanisms of immunodominance in cytotoxic T lymphocyte responses to minor histocompatibility antigens. Eur J Immunol 1997; 27: 421-430.
8. Pion S, Christianson GJ, Fontaine P et al. Shaping the repertoire of cytotoxic T-lymphocyte responses: explanation for the immunodominance effect whereby cytotoxic T lymphocytes specific for immunodominant antigens prevent recognition of nondominant antigens. Blood 1999; 93: 952-962.
9. Anderson LD, Savary CA, Mullen CA. Immunization of allogeneic bone marrow transplant recipients with tumor cell vaccines enhances graft-versus-tumor activity without exacerbating graft-versus-host disease. Blood 2000; 95: 2426-2433.
10. Anderson LJ, Petropoulos D, Everse LA, Mullen CA. Enhancement of graft-versus-tumor activity and graft-versus-host disease by pretransplant immunization of allogeneic bone marrow donors with a recipient-derived tumor cell vaccine. Cancer Res 1999; 59: 1525-1530.
11. Fontaine P, Roy-Proulx G, Knafo L et al. Adoptive transfer of minor histocompatibility antigen-specific T lymphocytes eradicates leukemia cells without causing graft-versus-host disease. Nat Med 2001; 7: 789-794.
12. Wei ML, Cresswell P. HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides. Nature 1992; 356: 443-446.
13. Restifo, NP, Esquivel F, Asher AL et al. Defective presentation of endogenous antigens by a murine sarcoma: implications for the failure of an anti-tumor immune response. J Immunol 1991; 147: 1453-1459.
14. Townsend A, Bodmer H. Antigen recognition by class I-restricted T lymphocytes. Ann Rev Immunol 1989; 7: 601-624.
15. Greenfield A, Scott D, Pennisi D et al. An H-YDb epitope is encoded by a novel mouse Y chromosome gene. Nat Genet 1996; 14: 474-478.
16. Everse LA, Anderson LD, Rooijen N, Mullen CA. Bone marrow transplant conditioning intensified with liposomal clodronate to eliminate residual host antigen presenting cells fails to ameliorate GVHD and increases peri-BMT mortality. Transplantation 2001; 71: 611-618.
17. Sercarz EE, Lehmann PV, Ametani A et al. Dominance and crypticity of T cell antigenic determinants. Annu Rev Immunol 1993; 11: 729-766.
18. Yewdell JW, Bennink JR. Immunodominance in major histocompatibility complex class I-restricted T lymphocyte responses. Annu Rev Immunol 1999; 17: 51-88.
19. Bastin J, Rothbard J, Davey J et al. Use of synthetic peptides of influenza nucleoprotein to define epitopes recognized by class I-restricted cytotoxic T lymphocytes. J Exp Med 1987; 165: 1508-1523.
20. Townsend AR, Gotch FM, Davey J. Cytotoxic T cells recognize fragments of the influenza nucleoprotein. Cell 1985; 42: 457-467.
21. Villanueva MS, Sijts AJ, Pamer EG. Listeriolysin is processed efficiently into an MHC class I-associated epitope in Listeria monocytogenes-infected cells. J Immunol 1995; 155: 5227-5233.
22. Choi EY, Yoshimura Y, Christianson GJ et al. Quantitative analysis of the immune response to mouse non-MHC transplantation antigens in vivo: the H60 histocompatibility antigen dominates over all others. J Immunol 2001; 166: 4370-A379.
23. Dey B, Yang Y-G, Preffer F et al. The fate of donor T-cell receptor transgenic T cells with known host antigen specificity in a graft-versus-host disease model. Transplantation 1999; 68: 141-149.
24. Walter EA, Greenberg PD, Gilbert MJ et al. Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor. N Engl J Med 1995; 333: 1038-1044.
25. Scott D, Addey C, Ellis P et al. Dendritic cells permit identification of genes encoding MHC class II-restricted epitopes of transplantation antigens. Immunity 2000; 12: 711-720.