Acute gastroenteritis in children: What role for antibacterials?

Pediatric Drugs

Volumn 5, Issue 5, 2003, Pages 279-290

  Phavichitr, Nopaorn ^a   Catto Smith, Anthony G ^a  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; ANTIBIOTIC AGENT; AZITHROMYCIN; AZTREONAM; BISMUTH SALICYLATE; CEFOTAXIME; CEFTRIAXONE; CEPHALOSPORIN DERIVATIVE; CHLORAMPHENICOL; CIPROFLOXACIN; CLARITHROMYCIN; CLINDAMYCIN; COLISTIN; COTRIMOXAZOLE; DOXYCYCLINE; ERYTHROMYCIN; FURAZOLIDONE; GENTAMICIN; METRONIDAZOLE; NALIDIXIC ACID; NEOMYCIN; PROBIOTIC AGENT; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TETRACYCLINE; TRIMETHOPRIM; UNINDEXED DRUG; VANCOMYCIN; ZINC;

ACUTE GASTROENTERITIS; AEROMONAS; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTHROPATHY; BACTERIAL TRANSMISSION; BREAST FEEDING; CAMPYLOBACTER; CHOLERA; CHONDROPATHY; CLINICAL FEATURE; CLINICAL TRIAL; CLOSTRIDIUM DIFFICILE; DIET SUPPLEMENTATION; DISEASE COURSE; DISEASE SEVERITY; DRUG CHOICE; DRUG CONTRAINDICATION; DRUG INDICATION; DRUG INDUCED DISEASE; ERADICATION THERAPY; ESCHERICHIA COLI; FECES ANALYSIS; HUMAN; IMMUNOCOMPETENCE; INFECTION CONTROL; INFECTION PREVENTION; LACTOBACILLUS; PLESIOMONAS; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; SALMONELLA; SHIGELLA; SHIGELLOSIS; TRAVELLER DIARRHEA; TREATMENT INDICATION; TYPHOID FEVER; VIBRIO CHOLERAE; VIRUS INFECTION; YERSINIA;

EID: 0038240864     PISSN: 11745878     EISSN: None     Source Type: Journal    
DOI: 10.2165/00128072-200305050-00001     Document Type: Review

References (108)

1. Armon K, Stephenson T, MacFaul R, et al. An evidence and consensus based guideline for acute diarrhoea management. Arch Dis Child 2001; 85: 132-42
2. Harlem G. WHO report on infectious disease: removing the obstacle to healthy development. Brunotland: World Health Organization, 1999
3. Khuffash FA, Sethi SK, Shaltout AA. Acute gastroenteritis: clinical features according to etiologic agents. Clin Pediatr 1988; 27 (8): 365-8
4. Fruhwirth M, Heininger U, Ehlken B, et al. International variation in disease burden of rotavirus gastroenteritis in children with community- and nosocomically-acquired infection. Pediatr Infect Dis J 2001; 20 (8): 784-91
5. Gastanaduy AS, Begue RE. Acute gastroenteritis. Clin Pediatr 1999; 38: 1-12
6. Crowley DS, Ryan MJ, Wall PG. Gastroenteritis in children under 5 years of age in England and Wales. Communicable Dis Rep CDR Rev 1997; 7: R82-6
7. Picketing LK. Antimicrobial therapy of gastrointestinal infections. Pediatr Clin North Am 1983; 30 (2): 373-85
8. Fasano A. Intestinal infections. In: Walker WA, Durie PR, Hamilton JR, et al., editors. Pediatric gastrointestinal disease: pathophysiology, diagnosis, management. 3rd ed. Hamilton (ON): BC Decker Inc., 2000: 463-84
9. Ashkenazi S, Cleary TG. Antibiotic treatment of bacterial gastroenteritis. Pediatr Infect Dis J 1991; 10: 140-8
10. Guerrant RL, Gilder TV, Steiner TS, et al. Practice guidelines for the management of infectious diarrhea. Clin Infect Dis 2001; 32: 331-50
11. Sazawal S, Black RE, Bhan MK, et al. Zinc supplementation in young children with acute diarrhoea in India. N Engl J Med 1995; 333: 839-44
12. Goossens H, Sprenger MJ. Community acquired infections and bacterial resistance. BMJ 1998; 317: 654-7
13. Red book 2000: report of the committee on infectious diseases. 25th ed. Elk Grove Village (IL): American Academy of Pediatrics, 2000
14. Murphy MS. Guidelines for managing acute gastroenteritis based on a systematic review of published research. Arch Dis Child 1998; 79: 279-84
15. Tauze RV, Puhr ND, Wells JG, et al. Antimicrobial resistance of Shigella isolates in the USA: the importance of international travelers. J Infect Dis 1990; 162: 1107-11
16. Ahmed AA, Osman H, Mansour AM, et al. Antimicrobial agent resistance in bacterial isolates from patients with diarrhea and urinary tract infection in the Sudan. Am J Trop Med Hyg 2000; 63 (5-6): 259-63
17. Wasfy MO, Oyofo BA, David JC, et al. Isolation and antibiotic susceptibility of Salmonella, Shigella, and Campylobacter from acute enteric infections in Egypt. J Health Pop Nutr 2000; 18 (1): 33-8
18. Sirivichayakul C, Thisyakorn U. Severe shigellosis in childhood. Southeast Asian J Trop Med Public Health 1998; 29 (3): 555-9
19. Jamal WY, Rotimi VO, Chugh TD, et al. Prevalence and susceptibility of Shigella species to 11 antibiotics in Kuwait teaching hospital. J Chemother 1998; 10 (4): 285-90
20. Salam MA, Dhar U, Khan WA, et al. Randomised comparison of ciprofloxacin suspension and pivmecillinam for childhood shigellosis. Lancet 1998; 352 (9127): 522-7
21. Rawashdeh MO, Ababneh AM, Shurman AA. Shigellosis in Jordanian children: a clinico-epidemiologic prospective study and susceptibility to antibiotics. J Trop Pediatr 1994; 40: 355-9
22. Hoge CW, Gambel JM, Srijan A, et al. Trends in antibiotic resistance among diarrheal pathogens isolated in Thailand over 15 years. Clin Infect Dis 1998; 26: 341-5
23. Khan WA, Seas C, Dhar U, et al. Treatment of shigellosis (V): comparison of azithromycin and ciprofloxacin: a double-blind, randomised, controlled trial. Ann Intern Med 1997; 126: 697-703
24. Lee WS, Puthucheary SD, Parasakthi N. Extra-intestinal non-typhoidal Salmonella infections in children. Ann Trop Paediatr 2000; 20: 125-9
25. Kupperman N. Occult bacteremia in young febrile children. Pediatr Clin North Am 1999; 46: 1073-109
26. Wittler RR, Bass JW. Non-typhoidal Salmonella enteric infections and bacteremia. Pediatr Infect Dis J 1989; 8: 364-7
27. Edelman R, Levine MM. Summary of an international workshop on typhoid fever. Rev Infect Dis 1986; 8: 329-49
28. Kabra SK, Madhulika, Talati A, et al. Multidrug-resistance typhoid fever. Trop Doctor 2000; 30 (4): 195-7
29. Okome-Nkoumou M, Ayo Nkana E, Bekale J, et al. Typhoid and paratyphoid fever in adults in the internal medicine department at Libreville (Gabon) [in French]. Sante 2000; 10 (3): 205-9
30. Barbara G, Stanghellini V, Berti-Ceroni C, et al. Role of antibiotic therapy on long-term germ excretion in faeces and digestive symptoms after Salmonella infection. Aliment Pharmacol Ther 2000; 14 (9): 1127-31
31. Murase T, Yamada M, Muto T, et al. Fecal excretion of Salmonella enterica serovar typhimurium following a food-borne outbreak. J Clin Microbiol 2000; 38 (9): 3495-7
32. Sirinavin S, Garner P. Antibiotics for treating salmonella gut infections (Cochrane Review). Available in the Cochrane Library (database on disk and CD ROM]. Updated quarterly. The Cochrane Collaboration; issue 2. Oxford: Oxford Update Software, 2000
33. Fey PD, Safranek TJ, Rupp ME, et al. Ceftriaxone-resistant salmonella infection acquired by a child from cattle. N Engl J Med 2000; 342 (17): 1242-9
34. Doherty CP, Saha SK, Cutting WA. Typhoid fever, ciprofloxacin and growth in young children. Ann Trop Paediatr 2000; 20 (4): 297-303
35. Cherubin CE, Kowalsky J. Non-typhoidal Salmonella carrier state treated with norfloxacin. Am J Gastroenterol 1990; 85: 100-1
36. Frenck Jr RW, Nakhla I, Sultan Y, et al. Azithromycin versus ceftriaxone for the treatment of uncomplicated typhoid fever in children. Clin Infect Dis 2000; 31 (5): 1134-8
37. Chinh NT, Parry CM, Ly NT, et al. A randomized controlled comparison of azithromycin and ofloxacin for treatment of multidrug-resistant or nalidixic acid-resistant enteric fever. Antimicrob Agents Chemother 2000; 44 (7): 1855-9
38. Butler T, Sridhar CB, Daga MK, et al. Treatment of typhoid fever with azithromycin versus chloramphenicol in a randomized multicentre trial in India. J Antimicrob Chemother 1999; 44 (2): 243-50
39. Girgis NI, Butler T, Frenck RW, et al. Azithromycin versus ciprofloxacin for treatment of uncomplicated typhoid fever in a randomized trial in Egypt that included patients with multidrug resistance. Antimicrob Agents Chemother 1999; 43 (6): 1441-4
40. Ashkenazi S, Danziger Y, Varsano Y, et al. Treatment of campylobacter gastroenteritis. Arch Dis Child 1987; 62: 84-5
41. Allos BM. Campylobacter jejuni infections: update on emerging issues and trends. Clin Infect Dis 2001; 32: 1201-6
42. Wassenaar TM, Blaser MJ. Pathophysiology of Campylobacter jejuni infections of humans. Microb Infect 1999; 1 (12): 1023-33
43. Altekruse SF, Stern NJ, Fields PI, et al. Campylobacter jejuni: an emerging foodborne pathogen. Emerg Infect Dis 1999; 5 (1): 28-35
44. Allos BM. Association between Campylobacter infection and Guillain-Barre syndrome. J Infect Dis 1997; 176 Suppl. 2: S125-8
45. Salazar-Lindo E, Sack RB, Chea-Woo E, et al. Early treatment with erythromycin of Campylobacter jejuni-associated dysentery in children. J Pediatr 1986; 109: 355-60
46. Afset JE, Maeland JA. Erythromycin and ciprofloxacin resistant Campylobacter jejuni [in Norwegian]. Tidsskrift for Den Norske Laegeforening 2001; 121 (18): 2152-4
47. Smith KE, Besser JM, Hedberg CW, et al. Quinolone-resistant Campylobacter jejuni infections in Minnesota, 1992-1998. Investigation Team. N Engl J Med 1999; 340 (20): 1525-32
48. Fields PI, Swerdlow DL. Campylobacter jejuni. Clin Lab Med 1999; 19 (3): 489-504
49. Aarestrup FM, Wegener HC. The effects of antibiotic usage in food animals on the development of antimicrobial resistance of importance for humans in Campylobacter and Escherichia coli. Microb Infect 1999; 1 (8): 639-44
50. Teuber M. Spread of antibiotic resistance with food-borne pathogens. Cellular Mol Life Sci 1999; 56 (9-10): 755-63
51. Noguera-Obenza M, Cleary TG. Diarrheogenic Escherichia coli. Curr Probl Pediatr 1999; 29: 208-16
52. Fagundes-Neto U, Scaletsky IC. The gut at war: the consequences of enteropathogenic Escherichia coli infection as a factor of diarrhea and malnutrition. Sao Paulo Med J 2000; 118 (1): 21-9
53. Clausen CR, Christie DL. Chronic diarrhea in infants caused by adherent enteropathogenic Escherichia coli. J Pediatr 1982; 100 (3): 358-61
54. DeVinney R, Gauthier A, Abe A, et al. Enteropathogenic Escherichia coli: a pathogen that inserts its own receptor into host cells. Cell Mol Life Sci 1999; 55 (6-7): 961-76
55. Newburg DS. Do the binding properties of oligosaccharides in milk protect human infants from gastrointestinal bacteria. J Nutr 1997; 127 (5 Suppl.): 980-4S
56. DuPont HL, Ericsson CD. Prevention and treatment of traveler's diarrhea. N Engl J Med 1993; 328 (25): 1821-6
57. Wolfe MS. Protection of travelers. Clin Infect Dis 1997; 25: 177-86
58. Gomi H, Jiang ZD, Adachi JA, et al. In vitro antimicrobial susceptibility testing of bacterial enteropathogens causing traveler's diarrhea in four geographic regions. Antimicrob Agents Chemother 2001; 45 (1): 212-6
59. Vila J, Vargas M, Ruiz J, et al. Quinolone resistance in enterotoxigenic Escherichia coli causing diarrhea in travelers to India in comparison with other geographical areas. Antimicrob Agents Chemother 2000; 44 (6): 1731-3
60. Ansdell VE, Ericsson CD. Prevention and empiric treatment of traveler's diarrhea. Med Clin North Am 1999; 83 (4): 945-73
61. Rocchi G, Capozzi M. Enterohemorrhagic Escherichia coli O157:H7 infection [in Italian]. Recenti Prog Med 1999; 90 (11): 613-8
62. Robson WL. Haemolytic uraemic syndrome. Pediatr Drugs 2001; 2 (4): 243-52
63. Keene WE, McAnulty JM, Hoesly FC, et al. A swimming-associated outbreak of hemorrhagic colitis caused by Escherichia coli O157:H7 and Shigella sonnei. N Engl J Med 1994; 331: 579-84
64. Mariani-Kurkdjian P, Bingen E. Hemolytic-uremic syndrome: microbiological aspects. Arch Pediatr 2001; 8 Suppl. 4: 785-91S
65. Loirat C. Post-diarrhea hemolytic-uremic syndrome: clinical aspects. Arch de Pediatr 2001; 8 Suppl. 4: 776-84S
66. Pavia AT, Nichols CR, Green DP, et al. Hemolytic-uremic syndrome during an outbreak of Escherichia coli O157:H7 infections in institutions for mentally retarded persons: clinical and epidemiologic observations. J Pediatr 1990; 116: 544-51
67. Griffin PM, Tauxe RV. The epidemiology of infections caused by Escherichia coli O157:H7, other enterohemorrhagic E. coli and the associated hemolytic uremic syndrome. Epidemiol Rev 1991; 13: 60-98
68. Siegler RL, Pavia AT, Christofferson RD, et al. A 20-year population-based study of postdiarrheal hemolytic uremic syndrome in Utah. Pediatrics 1994; 94: 35-40
69. Wong CS, Jelacic S, Habeeb RL, et al. The risk of the hemolytic-uremic syndrome after antibiotic treatment of Escherichia coli O157:H7 infections. N Engl J Med 2000; 342: 1930-6
70. Igarashi T, Inatomi J, Wake A, et al. Failure of pre-diarrheal antibiotics to prevent hemolytic uremic syndrome in serologically proven Escherichia coli O157:H7 gastrointestinal infection. J Pediatr 1999; 135: 768-9
71. Law D, Chart H. Enteroaggregative Escherichia coli. J Applied Microbiol 1998; 84 (5): 685-97
72. Chan KN, Phillips AD, Knutton S, et al. Enteroaggregative Escherichia coli: another cause of acute and chronic diarrhoea in England. J Pediatr Gastroenterol Nutr 1994; 18: 87-91
73. Itoh Y, Nagano I, Kunishima M. Laboratory investigation of enteroaggregative Escherichia coli O untypeable:H10 associated with a massive outbreak of gastrointestinal illness. J Clin Microbiol 1997; 35: 2546-50
74. Yamamoto T, Echeverria P, Yokota T. Drug resistance and adherence to human intestines of enteroaggregative Escherichia coli. J Infect Dis 1992; 165: 744-9
75. Faruque SM, Albert MJ, Mekalanos JJ. Epidemiology, genetics, and ecology of toxigenic Vibrio cholerae. Microbiol Mol Biol Rev 1998; 62 (4): 1301-14
76. Swerdlow DL, Ries AA. Vibrio cholerae non-OI: the eighth pandemic. Lancet 1993; 342: 382-3
77. Rabbani GH, Greenough III WB. Food as a vehicle of transmission of cholera. J Diarrhoeal Dis Res 1999; 17 (1): 1-9
78. Hossain MS, Salam MA, Rabbani GH, et al. Vibrio cholerae O139 Bengal: a descriptive study. J Health Pop Nutr 2000; 18 (1): 27-32
79. McFarland LV, Brandmarker SA, Guandalini S. Pediatric Clostridium difficile: a phantom menace or clinical reality. J Pediatr Gastroenterol Nutr 2000; 31: 220-31
80. Yassin SF, Young-Fadok TM, Zein NN, et al. Clostridium difficile-associated diarrhea and colitis. Mayo Clin Proc 2001; 76 (7): 725-30
81. Freeman J, Wilcox MH. Antibiotics and Clostridium difficile. Microbes Infect 1999; 1 (5): 377-84
82. Gorenek L, Dizer U, Besirbellioglu B, et al. The diagnosis and treatment of Clostridium difficile in antibiotic-associated diarrhea. Hepatogastroenterology 1999; 46 (25): 343-8
83. Gorschluter M, Glasmacher A, Hahn C, et al. Clostridium difficile infection in patients with neutropenia. Clin Infect Dis 2001; 33 (6): 786-91
84. Wilcox MH, Smyth ET. Incidence and impact of Clostridium difficile infection in the UK, 1993-1996. J Hospital Infect 1998; 39 (3): 181-7
85. Alvarez-Olmos MI, Oberhelman RA. Probiotic agents and infectious diseases: a modern perspective on a traditional therapy. Clin Infect Dis 2001; 32: 1567-76
86. Vanderhoof JA. Probiotics: future directions. Am J Clin Nutr 2001; 73: 1152-5S
87. Vanderhoof JA, Young RJ. Use of probiotics in childhood gastrointestinal disorders. J Pediatr Gastroenterol Nutr 1998; 27: 323-32
88. Biller JA, Katz AJ, Flores AF, et al. Treatment of recurrent Clostridium difficile colitis with Lactobacillus GG. J Pediatr Gastroenterol Nutr 1995; 21: 224-6
89. Buts JP, Corthier G, Delmee M. Saccharomyces boulardii for Clostridium difficile-associated enteropathies in infants. J Pediatr Gastroenterol Nutr 1993; 16: 419-25
90. Vanderhoof JA, Whitney DB, Antonson DL, et al. Lactobacillus GG in the prevention of antibiotic-associated diarrhea in children. J Pediatr 1999; 135: 564-8
91. Arvola T, Laiho K, Torkkeli S, et al. Prophylactic Lactobacillus GG reduces antibiotic-associated diarrhea in children with respiratory infections: a randomized study. Pediatrics 1999; 104: 1121-2
92. Cover TL, Aber RC. Yersinia enterocolitica. N Engl J Med 1989; 321 (1): 16-24
93. Abdel-Haq NM, Asmar BI, Abuhammour WM, et al. Yersinia enterocolitica infection in children. Pediatr Infect Dis J 2000; 19: 954-8
94. Tuohy AM, O'Gorman M, Byington C, et al. Yersinia enterocolitis mimicking Crohn's disease in toddler. Pediatrics 1999; 104 (3): E36
95. Lamps LW, Madhusudham KT, Greenson JK, et al. The role of Yersinia enterocolitica and Yersinia pseudotuberculosis in granulomatous appendicitis: a histologic and molecular study. Am J Surg Pathol 2001; 25 (4): 508-15
96. Bien JP. Anticipatory guidance and chitterlings. J Pediatr 1998; 133 (5): 712-3
97. Satterthwaite P, Pritchard K, Floyd D, et al. A case-control study of Yersinia enterocolitica infections in Auckland. Aust NZ Public Health 1999; 23 (5): 482-5
98. Pai CH, Gillis F, Tuomanen E, et al. Clinical and laboratory observations: placebo-controlled double-blind evaluation of trimethoprim-sulfamethoxazole treatment of Yersinia enterocolitica gastroenteritis. J Pediatr 1984; 104 (2): 308-11
99. San Joaquin VH, Pickett DA. Aeromonas-associated gastroenteritis in children. Pediatr Infect Dis J 1988; 7 (1): 53-7
100. Teka T, Faruque AS, Hossain MI, et al. Aeromonas-associated diarhoea in Bangladeshi children: clinical and epidemiological characteristics. Ann Trop Paediatr 1999; 19: 15-20
101. Albert MJ, Ansaruzzaman M, Talukder KA, et al. Prevalence of enterotoxin genes in Aeromonas spp isolated from children with diarrhea, healthy controls and the environment. J Clin Microbiol 2000; 38 (10): 3785-90
102. Ko WC, Lee HC, Chuang YC, et al. Clinical features and therapeutic implications of 104 episodes of monomicrobial Aeromonas bacteraemia. J Infect 2000; 40 (3): 267-73
103. Ghenghesh KS, Bara F, Bukris B, et al. Characterization of virulence factors of Aeromonas isolated from children with and without diarrhoea in Tripoli, Libya. J Diarrhoeal Dis Res 1999; 17 (2): 75-80
104. Taher AA, Rao BN, Alganay KG, et al. An outbreak of acute gastroenteritis due to Aeromonas sobria in Benghazi, Libyan Arab Jamahiriya. East Mediterr Health J 2000; 6 (2-3): 497-9
105. Juan HJ, Tang RB, Wu TC, et al. Isolation of Aeromonas hydrophila in children with diarrhea. J Microbiol Immunol Infect 2000; 33 (2): 115-7
106. Kain KC, Kelly MT. Clinical features, epidemiology, and treatment of Plesiomonas shigelloides diarrhea. J Clin Microbiol 1989; 27: 998-1001
107. Wong TY, Tsui HY, So MK, et al. Plesiomonas shigelloides infection in Hong Kong: retrospective study of 167 laboratory-confirmed cases. Hong Kong Med J 2000; 6 (4): 375-80
108. Shigematsu M, Kaufmann ME, Charlett A, et al. An epidemiological study of Plesiomonas shigelloides diarrhoea among Japanese travelers. Epidemiol Infect 2000; 125 (3): 523-30