Anti-complement activity in the saliva of phlebotomine sand flies and other haematophagous insects

Parasitology

Volumn 127, Issue 1, 2003, Pages 87-93

  Cavalcante, R R ^a   Pereira, M H ^b   Gontijo, N F ^b  

^a FEDERAL UNIVERSITY OF PIAUÍ   (Brazil)

^b FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

Author keywords

Complement inhibition; Haematophagous insects; Haematophagy; Insect saliva; Leishmania transmission; Lutzomyia longipalpis

Indexed keywords

COMPLEMENT; IMMUNOMODULATING AGENT; VACCINE;

AEDES AEGYPTI; ARTICLE; BLOOD; COMPLEMENT INHIBITION; COMPLEMENT SYSTEM; CONTROLLED STUDY; CTENOCEPHALIDES; DRUG ACTIVITY; DRUG TARGETING; HEAT TOLERANCE; IMMUNOMODULATION; LEISHMANIA; NONHUMAN; PANSTRONGYLUS; PARASITE TRANSMISSION; PARASITE VECTOR; PHLEBOTOMUS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DENATURATION; PROTEIN STABILITY; PSYCHODIDAE; RHODNIUS; SALIVA; THERMOSTABILITY; TRIATOMA; TRIATOMINAE;

ANIMALS; COMPLEMENT INACTIVATOR PROTEINS; COMPLEMENT PATHWAY, CLASSICAL; CRICETINAE; DOGS; FLEAS; INSECT VECTORS; INSECTS; MOLECULAR WEIGHT; PSYCHODIDAE; SALIVARY GLANDS;

AEDES AEGYPTI; ARACHNIDA; CTENOCEPHALIDES; CTENOCEPHALIDES FELIS; FELIS; HEXAPODA; INSECTA; LUTZOMYIA LONGIPALPIS; PANSTRONGYLUS; PANSTRONGYLUS MEGISTUS; PHLEBOTOMINAE; PSYCHODIDAE; RHODNIUS; RHODNIUS PROLIXUS; SIPHONAPTERA (FLEAS); TRIATOMA; TRIATOMA BRASILIENSIS; TRIATOMINAE; VERTEBRATA;

EID: 0038235210     PISSN: 00311820     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0031182003003329     Document Type: Article

References (37)

1. ADLER, S. & THEODOR, O. (1926). The mouthparts, alimentary tract, and salivary apparatus of the female in Phlebotomus papatasi. Annals of Tropical Medicine and Parasitology 20, 109-140.
2. ARLAUD, G. J., VOLANAKIS, J. E., THIELENS, N. M., NARAYANA, S. V., ROSSI, V. & XU, Y. (1998). The atypical serine proteases of the complement system. Advances in Immunology 69, 249-307.
3. BELKAID, Y., VALENZUELA, J. G., KAMHAWI, S., ROWTON, E., SACKS, D. L. & RIBEIRO, J. M. C. (2000). Delayed-type hypersensitivity to Phlebotomus papatasi sand fly bite: an adaptative response induced by the fly ? Proceedings of the National Academy of Sciences, USA 97, 6704-6709.
4. BEZERRA, H. S. S. & TEIXEIRA, M. J. (2001). Effect of Lutzomyia whitmani (Diptera: Psychodidae) salivary gland lysates on Leishmania (Viannia) braziliensis infection in BALBl/c mice. Memórias do Instituto Oswaldo Cruz 96, 349-351.
5. CAVALCANTE, R. R., PERIERA, M. H. & GONTIJO, N. F. (2002). Inhibitory activity against the complement system in the Lutzomyia longipalpis and Lutzomyia migonei saliva. Entomologia y Vectores 9, 87.
6. CHARLAB, R., VALENZUELA, J. G., ROWTON, E. D. & RIBEIRO, J. M. C. (1999). Toward an understanding of the biochemical and pharmacological complexity of the saliva of a haematophagous sand fly Lutzomyia longipalpis. Proceedings of the National Academy of Sciences, USA 96, 15155-15160.
7. EIRAS, A. E. & JEPSON, P. C. (1991). Host location by Aedes aegypti (Diptera; Culicidae): a wind tunnel study of chemical cues. Bulletin of Entomological Research 81, 151-160.
8. GILLESPIE, R. D., MBOW, M. L. & TITUS, R. G. (2000). The immunomodulatory factors of bloodfeeding arthropod saliva. Parasite Immunology 7, 319-331.
9. HALL, L. R. & TITUS, R. G. (1995). Sand fly vector saliva selectively modulates macrophage functions that inhibit killing of Leishmania major and nitric oxide production. Journal of Immunology 155, 3501-3506.
10. KAMHAWI, S. (2000). The biological and immunomodulatory properties of sand fly saliva and its role in the establishment of Leishmania infections. Microbes and Infection 2, 1765-1773.
11. KAMHAWI, S., BELKAIDE, Y., MODI, G., ROWTON, E. & SACKS, D. (2000). Protection against cutaneous leishmaniasis resulting from bites of uninfected sand flies. Science 290, 1351-1354.
12. LAWRIE, C. H., RANDOLPH, S. E. & NUTTALL, P. A. (1999). Ixodes ticks: serum sensitivity of anticomplement activity. Experimental Parasitology 93, 207-214.
13. LIMA, H. C. & TITUS, R. G. (1996). Effects of sand fly vector saliva on development of cutaneous lesions and the immune response to Leishmania brasiliensis in BALB/c mice. Infection and Immunology 64, 5442-5445.
14. MAKRIDES, S. C. (1998). Therapeutic inhibition of the complement system. Pharmacological Reviews 50, 59-87.
15. MELO, M. N., WILLIAMS, P. & TAFURI, W. L. (2001). Influence of lysates of the salivary glands of Lutzomyia longipalpis on the development of a Leishmania major-like parasite in the skin of golden hamster. Annals of Tropical Medicine and Parasitology 95, 59-68.
16. MODI, G. B. & TESH, R. B. (1983). A simple technique for mass rearing Lutzomyia longipalpis and Phlebotomus papatasi (Diptera: Psychodidae) in the laboratory. Journal of Medical Entomology 20, 568-569.
17. MORRIS, R. V., SHOEMAKER, C. B., DAVID, J. R., LANZARO, G. C. & TITUS, R. G. (2001). Sandfly maxadilan exacerbates infection with Leishmania major and vaccinating against it protects against L. major infection. Journal of Immunology 167, 5226-5230.
18. MOSSER, D. M. & BRITTINGHAM, A. (1997). Leishmania, macrophages and complement: a tale of subversion and exploitation. Parasitology 115 (Suppl.), S9-S23.
19. NORONHA, F. S. M., NUNES, A. C., SOUZA, K. T., MELO, M. N. & RAMALHO-PINTO, F. J. (1998). Differential sensitivity of New World Leishmania spp. promastigotes to complement-mediated lysis: correlation with the expression of three parasite polypeptides. Acta Tropica 69, 17-29.
20. NUNES, A. C. & RAMALHO-PINTO, F. J. (1996). Complement resistance of Leishmania amazonensis promastigotes is independent of parasite proteases and lysis of sensitive forms is not due to natural antibodies in normal human serum. Brazilian Journal of Medical and Biological Research 29, 1633-1640.
21. PAPATEODOROU, V. & BROSSARD, M. (1987). C3 levels in the area of rabbits infested and reinfested with Ixodes ricinus L. and in midguts of fed ticks. Experimental and Applied Acarology 3, 53-59.
22. RIBEIRO, J. M., ROSSIGNOL, P. A. & SPIELMAN, A. (1986). Blood-finding strategy of a capillary-feeding sandfly, Lutzomyia longipalpis. Comparative Biochemistry and Physiology A83, 683-686.
23. RIBEIRO, J. M. (1987a). Role of saliva in blood-feeding by arthropods. Annual Review of Entomology 32, 463-478.
24. RIBEIRO, J. M. (1987b). Ixodes dammini: salivary anti-complement activity. Experimental Parasitology 64, 347-353.
25. RIBEIRO, J. M., VACHEREAU, A., MODI, G. B. & TESH, R. B. (1989). A novel vasodilatory peptide from the salivary glands of the sand fly Lutzomyia longipalpis. Science 243, 212-214.
26. RIBEIRO, J. M. C. (1995). Blood-feeding Arthropods: live syringes or invertebrate pharmacologists? Infectious Agents and Disease 4, 143-152.
27. RIBEIRO, J. M. C., SCHNEIDER, M., ISAIAS, T., JURBERG, J. C., GALVÃO, C. & GUIMARÃES, J. A. (1998). Role of salivary antihemostatic components in blood feeding by triatomine bugs (Heteroptera). Journal of Medical Entomology 35, 599-610.
28. TITUS, R. G. & RIBEIRO, J. M. C. (1988). Salivary gland lysates from the sand fly Lutzomyia longipalpis enhance Leishmania infectivity. Science 239, 1307-1308.
29. TITUS, R. G. & RIBEIRO, J. M. C. (1990). The role of vector saliva in transmission of arthropod borne disease. Parasitology 6, 157-160.
30. THEODOS, C. M., RIBEIRO, J. M. C. & TITUS, R. G. (1991) Analyses of the enhancing effect of the sand fly saliva on Leishmania infection in mice. Infection and Immunity 59, 1592-1598.
31. THEODOS, C. M. & TITUS, R. G. (1993). Salivary gland material from the sand fly Lutzomyia longipalpis has an inhibitory effect on macrophage function in vitro. Parasite Immunology 15, 481-487.
32. VALENZUELA, J. G., CHARLAB, R., MATHER, T. N. & RIBEIRO, J. M. (2000). Purification, cloning, and expression of a novel salivary anticomplement protein from the tick, Ixodes scapularis. Journal of Biological Chemistry 25, 18717-18723.
33. VALENZUELA, J. G., BELKAIDE, Y., GARFIELD, M. K., MENDEZ, S., KAMHAWI, S., ROWTON, E. D., SACKS, D. L. & RIBEIRO, J. M. C. (2001). Toward a defined anti-Leishmania vaccine targeting vector antigens: characterization of a protective salivary protein. Journal of Experimental Medicine 194, 331-342.
34. WARBURG, A., SARAIVA, E., LANZARO, G. C., TITUS, R. G. & NEVA, F. (1994). Saliva of Lutzomyia longipalpis sibling species differs in its composition and capacity to enhance leishmaniasis. Philosophical Transactions of the Royal Society of London, B 345, 223-230.
35. WHALEY, K. & NORTH, J. (1997). Haemolytic assays for whole complement activity and individual components. In Complement: a Practical Approach (ed. Dodds, A. W. & Sim, R. B., I.P.), pp. 19-47. Oxford University Press Oxford.
36. WIKEL, S. K. & ALLEN, J. R. (1977). Acquired resistance to ticks. III. Cobra venom factor and the resistance response. Immunology 32, 457-465.
37. ZER, R., YAROSLAVISKI, I., ROSEN, L. & WARBURG, A. (2001). Effect of sand fly saliva on Leishmania uptake by murine macrophages. International Journal for Parasitology 31, 810-814.